Clinical trials: Pneumonia; Pulmonary Infection
Convalescence, Corona Virus Infection
Convalescent Plasma Therapy in Patients With COVID-19
Scientists and medical workers all around the world were running out of time to manage COVID-19. Several studies have been done to understand the disease and ultimately to find possible treatment.
- Conditions
- Convalescence, Corona Virus Infection, Plaque
- Trial name
- NCT04407208
- Testing
- Convalescent plasma
- Where
- Indonesia
- Volunteers
- 10 people
- Sponsor
- Biofarma
Virus; Pneumonia
A Survey of Psychological Status of Medical Workers and Residents in the Context of 2019 Novel Coronavirus Pneumonia
Due to the outbreak of 2019 Novel Coronavirus Pneumonia in Wuhan, Hubei province, medical staff and residents are facing great psychological pressure, the investigator plan to use electronic questionnaire to carry out…
- Trial name
- NCT04260308
- Where
- China
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology
Adjustment Disorder, Anxiety
Online MBCT for Adjustment Disorder During COVID-19: Efficacy, Mechanisms, and RCT
This study tested a 4-week, internet-based Mindfulness-Based Cognitive Therapy (MBCT) program designed to help people experiencing adjustment disorder during the COVID-19 pandemic.
- Conditions
- Adjustment Disorder, Anxiety, Depressive
- Trial name
- NCT07128017
- Testing
- Mindfulness-Based Cognitive Therapy (Internet-delivered), Progressive Muscle Relaxation (Internet-delivered), No Intervention - Waitlist Control
- Where
- Poland
- Volunteers
- 301 people
- Sponsor
- University of Warsaw
Severe Acute Respiratory Syndrome, Coronavirus
A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Vaccine CVnCoV in Healthy Adults for COVID-19
This study aims to evaluate the safety and reactogenicity profile after 1 and 2 dose administrations of CVnCoV at different dose levels.
- Conditions
- Severe Acute Respiratory Syndrome, Coronavirus, SARS-CoV-2, COVID-19
- Trial name
- NCT04449276
- Testing
- CVnCoV Vaccine
- Where
- 4 sites in Belgium, Germany
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- CureVac
COVID-19 Pandemic, Transplantation, Kidney
Seroprevalence of the Anti-SARS-CoV-2 Antibodies (Causing COVID-19) in Kidney Transplant Recipients in Severely Affected Region
Goal of this study is to evaluate the seroprevalence of anti-SARS-CoV-2 antibodies in patients after kidney transplantation who are one of the risk groups for the severe course of the infection and map the progression of the…
- Trial name
- SECOVtx (NCT04874740)
- Testing
- No intervention
- Where
- Czechia
- Volunteers
- 300 people
- Sponsor
- University Hospital Ostrava
COVID-19, Respiratory Distress Syndrome
Comparison of Two Respiratory Physiotherapy Treatments in Postcovid-19 Patients.
To test the effectiveness of a respiratory physiotherapy treatment plan in patients who have passed COVID-19, comparing two randomized groups, for the performance of different respiratory musculature training protocols.
- Trial name
- NCT05435443
- Testing
- PowerBreathe and PEP Therosold tools
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Universidad Católica de Ávila
COVID-19 Pneumonia, COVID-19 Respiratory Infection
Cromolyn Sodium for Treatment of COVID-19 Pneumonia
The study hypothesis is that cromolyn, when combined with standard COVID-19 treatment, will improve patient symptoms and reduce the number of days to improved quality of life.
- Conditions
- COVID-19 Pneumonia, COVID-19 Respiratory Infection, Pneumonia, Viral
- Trial name
- NCT05077917
- Testing
- Cromolyn Sodium
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Community-Acquired Pneumonia (CAP), Pneumonia
PromotIng Optimal Treatment for Community-acquired PNeumonia in EmErgency Rooms
In North America, up to 5% of preschoolers develop community-acquired pneumonia (CAP) every year. Pneumonia is the second-leading reason for paediatric hospitalization in both Canada and the US; approximately 20% of children…
- Trial name
- PIONEERS (NCT07099976)
- Testing
- The novel care pathway intervention, Usual Care Alone
- Where
- 6 sites in Canada
- Volunteers
- 698 people
- Sponsor
- Jeffrey Pernica
SARS-CoV2
Clinical Features of Severe Patients With COVID-19
As coronavirus disease 2019 (COVID-19) spreads across the world, the intensive care unit (ICU) community must prepare for the challenges associated with this pandemic.
- Trial name
- NCT04450017
- Testing
- The demographic, clinical, laboratory, and instrumental data
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Federal Research Clinical Center of Federal Medical & Biological Agency, Russia
Pulmonary Diseases, Tonsillar Hypertrophy
The Influence of Feeding Position on Pulmonary Morbidity in Young Children
Supine feeding position is associated with serous otitis media. The hypothesis is that supine feeding is associated with recurrent otitis media, tonsillar and adenoid hypertrophy and recurrent pneumonia secondary to recurrent…
- Conditions
- Pulmonary Diseases, Tonsillar Hypertrophy, Otitis Media, Dental Caries
- Trial name
- NCT00248391
- Testing
- upright feeding
- Where
- Israel
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Covid19
COVidIVERmectin: Ivermectin for Treatment of Covid-19
Prospective, multi-centre, randomized, double-blind trial to assess efficacy and safety of ivermectin for the treatment of initial infection with SARS-CoV2 infection.
- Trial name
- COVER (NCT04438850)
- Testing
- Ivermectin
- Where
- 5 sites in Italy
- Volunteers
- 93 people
- Sponsor
- IRCCS Sacro Cuore Don Calabria di Negrar
Child Development, Prenatal Infection
HEALthy Brain and Child Development Study - COVID-19 Supplement
The purpose of this study is to advance the scientific understanding of how a prenatal COVID-19 infection and associated psychological distress influences infant neurodevelopment.
- Conditions
- Child Development, Prenatal Infection, Prenatal Stress, Covid19
- Trial name
- NCT04713150
- Testing
- No Intervention
- Where
- 4 sites in United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
COVID-19, SARS-CoV 2
Convalescent Plasma for the Treatment of Patients With COVID-19
This expanded access program will provide access to COVID-19 convalescent plasma 150 or more individuals with moderate to severe or life-threatening manifestations of COVID-19, or documented to be at high risk of developing such…
- Trial name
- NCT04372368
- Testing
- COVID-19 Convalescent Plasma
- Where
- 6 sites in United States
- Sponsor
- University of Colorado, Denver
Hepatitis B, Chronic (CHB), Hepatitis B
Real-world Study Evaluating the Long-term Outcomes of Pegylated Interferon α-2b Treatment in the Families With Clusters of HBV Infection and Unfavorable Prognosis - A Prospective, Controlled, Multicenter, Cohort Study
Chronic hepatitis B can develop into cirrhosis and liver cancer, which seriously endangers the life and health of people. In China, HBV is mainly transmitted from mother to child, showing the phenomenon of family clusters.
- Conditions
- Hepatitis B, Chronic (CHB), Hepatitis B, Hepatitis B Virus (HBV)
- Trial name
- NCT07079150
- Testing
- Peg IFN-α-2b
- Where
- 2 sites in China
- Volunteers
- 1,500 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Pneumonia
Decreasing Unnecessary Antibiotics Prescribed for Possible Pneumonia Despite Normal Respiratory Rate and Oxygenation
The purpose of this study is to decrease unnecessary antibiotics prescribed to hospitalized patients for possible pneumonia by flagging patients with respiratory rates and oxygenation levels within reference ranges given prior…
- Trial name
- NCT05172791
- Testing
- Antibiotic stewardship messaging
- Where
- United States
- Volunteers
- 643 people
- Sponsor
- Brigham and Women's Hospital
Hospital Acquired Pneumonia
Pneumonia After Cardiovascular Surgery With Artificial Intelligence
This multicenter, prospective, observational study aims to address two primary objectives. The first objective is to demonstrate that hospital-acquired pneumonia (nosocomial pneumonia) following cardiac surgery can be predicted…
- Trial name
- NCT07745491
- Testing
- Not applicable- observational study
- Where
- Russia
- Volunteers
- 700 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
COVID-19, SARS CoV 2 Virus
Passive Detection- SARS-CoV-2 (COVID-19) A&M Breathalyzer (PROTECT Kiosk) for Operational Medicine
The primary objective of this effort will be to optimize and operationalize innovative passive surveillance systems and in parallel, the effort will identify, evaluate, and transition groundbreaking new technologies in…
- Conditions
- COVID-19, SARS CoV 2 Virus, COVID-19 Pneumonia, COVID-19 Respiratory Infection
- Trial name
- COVID-19 (NCT06402318)
- Testing
- A&M Breathalyzer PROTECT Kiosk
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Geneva Foundation
Pneumonia, Covid19
The Role of Sodium Bicarbonate as Adjuvant Treatment of Computed Tomography Identified COVID-19 Pneumonia
To report the possible role of S.B 8.4% in the treatment of COVID-19pneumonia.
- Trial name
- NCT04374591
- Testing
- Sodium Bicarbonate
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Mansoura University
Covid19
Lactoferrin in Covid-19 Hospitalized Patients
TRIAL LAC is a randomized double-blind non profit multicenter study with a nutritional product: bovine lactoferrin - Mosiac 200 mg.
- Trial name
- LAC (NCT04847791)
- Testing
- Bovine lactoferrin
- Where
- 2 sites in Italy
- Volunteers
- 194 people
- Sponsor
- Paolo Manzoni
COVID-19
Study Evaluating Diltiazem in Combination With Standard Treatment in the Management of Patients Hospitalized With COVID-19 Pneumonia
SARS-CoV-2 infection is responsible for hypoxemic pneumonia, which is sometimes serious and associated with excess mortality. To date, with the exception of dexamethasone, which has shown clinical efficacy by reducing the…
- Trial name
- DICOV (NCT05563168)
- Where
- 21 sites in France
- Sponsor
- Hospices Civils de Lyon
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