Clinical trials: Pneumonia
COVID-19, Molecular Sequence Variation
COVID-19 Genomic Sequencing for Nosocomial Outbreak Investigations
This is a tertiary care hospital-based prospective molecular epidemiology study in Montreal, Canada. When nosocomial transmission was suspected by local infection control teams' investigations, SARS-CoV-2 viral genomic sequencing…
- Conditions
- COVID-19, Molecular Sequence Variation, Nosocomial Infection
- Trial name
- NOSO-COVID (NCT05411562)
- Testing
- SARS-CoV-2 genomic sequencing
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
COVID-19
A Phase II Clinical Trial to Evaluate the Recombinant Vaccine for COVID-19 (Adenovirus Vector)
This is a phase II, randomised, double-blinded and placebo-controlled clinical trial in healthy adults above 18 years of age. This clinical trial is designed to evaluate the immunogenicity and safety of Ad5-nCoV which encodes for…
- Trial name
- CTII-nCoV (NCT04341389)
- Testing
- Recombinant novel coronavirus vaccine (Adenovirus type 5 vector)
- Where
- China
- Volunteers
- 508 people, healthy volunteers welcome
- Sponsor
- Institute of Biotechnology, Academy of Military Medical Sciences, PLA of China
Postoperative Pain, Postherniotomy Pain
Neurophysiological Characterization of Postherniotomy Pain
Sensory function is different in persistent postherniotomy pain patients than in operated controls, suggesting this to be a neuropathic pain syndrome.
- Conditions
- Postoperative Pain, Postherniotomy Pain, Neuropathic Pain
- Trial name
- NCT00719368
- Where
- 2 sites in Denmark
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
COVID-19 Respiratory Infection
Spa Rehabilitation, Antioxidant and Bioenergetic Supportive Treatment of Patients With Post-Covid-19 Syndrome
Our hypothesis - that 21 days of mountain spa rehabilitation with ubiquinol supplementation could to accelerate regeneration of patients with post-COVID-19 syndrome, based on the improving platelet mitochondrial bioenergetic…
- Trial name
- SpaCOVID (NCT05178225)
- Testing
- ubiquinol (reduced coenzyme Q10), mountain spa rehabilitation, 2x14 ml of peripheral blood collected in a tube with anticoagulant
- Where
- Slovakia
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Comenius University
Pneumococcal Pneumonia, Pneumonia, Bacterial
Phase I to Test a New Pneumococcal Vaccine
To obtain first-in-human data on a new candidate vaccine against Streptococcus pneumoniae in healthy adult and elderly volunteers.
- Trial name
- NCT03303976
- Testing
- Bioconjugate pneumococcal vaccine, Multivalent plain polysaccharide vaccine
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- LimmaTech Biologics AG
COVID-19
Hydroxychloroquine and Azithromycin as Prophylaxis for Healthcare Workers Dealing With COVID19 Patients
The main objective of this study is to assess the efficacy of the combination hydroxychloroquine and Azithromycin (HCQ and AZ) in reducing the infection risk among health care professionals in direct contact with COVID-19…
- Trial name
- MOPHYDA (NCT04354597)
- Testing
- HCQ & AZ
- Where
- Jordan
- Volunteers
- healthy volunteers welcome
- Sponsor
- King Hussein Cancer Center
COVID-19, Renal Transplant Infection
COVID-19 Infection
Post-transplant patients with COVID-19 infection who attended Shenzhen No. 3 Hospital from December 2022 to February 2023, and enrolled the general population with COVID-19 infection who were hospitalized during the same period…
- Trial name
- NCT05926076
- Testing
- Treatment plan
- Where
- China
- Volunteers
- 610 people, healthy volunteers welcome
- Sponsor
- Tianjin First Central Hospital
Lung Function Decreased, Obesity
Lung Functions in Menopausal Obese Women After COVID 19 Recovery
The COVID-19 pandemic has presented considerable challenges to global health services and dictates almost every aspect of medical practice and policy.
- Conditions
- Lung Function Decreased, Obesity, Menopause, Covid19
- Trial name
- NCT05008991
- Testing
- Spirometry
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Badr University
COVID19- Infection with SARS-CoV-2 Virus, SARS-CoV-2 Positive Patients
Impact of the Elevation Training Mask in CrossFit® Post-SARS-CoV-2 Infection.
Introduction: The Elevation Training Mask (ETM) could restore respiratory or hematological organic damages from the acute or post-infection phase of severe acute respiratory syndrome coronavirus 2 (SARSCoV2) because it would…
- Conditions
- COVID19- Infection with SARS-CoV-2 Virus, SARS-CoV-2 Positive Patients, COVID-19 Pulmonary Complications, SARS-CoV-2 Infection (Symptomatic)
- Trial name
- ETMEXCOVID (NCT06806124)
- Testing
- Elevation Training Mask
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Valladolid
COVID-19, Post-Acute COVID-19
Genetic Risk Factors for Multi-system Inflammatory Syndrome in Children and Pediatric Post COVID Condition
We will perform Whole Exome Sequencing on DNA from saliva. We will include: Children with a history of MIS-C; children with post-COVID condition; and controls in order to identify rare, high impact genetic variants in…
- Conditions
- COVID-19, Post-Acute COVID-19, Post-Acute COVID19 Syndrome, Multi-System Inflammatory Syndrome in Children
- Trial name
- GRIP (NCT05722717)
- Testing
- Saliva collection at home
- Where
- Netherlands
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Depression
Organized Self-Management Support Services for Chronic Depression
The purpose is to test the effectiveness of an organized care program for chronic or recurrent depression. Using a two-arm design, the investigators will randomly assign 300 participants with chronic or recurrent depression to…
- Trial name
- Stride (NCT01139060)
- Testing
- organized care program for chronic or recurrent depression
- Where
- 2 sites in United States
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
COVID-19
Antibody Responses in Contacts of COVID-19 Patients
After several cases of pneumonia with an unfamiliar etiology were observed at the end of 2019, the National Health Commission of China released more details about the epidemic in early 2020.
- Trial name
- NCT04444310
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cognitive Impairment, Covid19
The MentalPlus® for Assessment and Rehabilitation of Cognitive Function After Remission of the Symptoms of COVID-19
This study evaluates and rehabilitates the cognitive functions of attention, memory, visual perception, language, and executive by the mentalPlus® digital game of COVID-19 surviving patients after remission of symptoms.
- Conditions
- Cognitive Impairment, Covid19, Cognitive Dysfunction, Depression, Anxiety
- Trial name
- MP-COVID (NCT04632719)
- Testing
- The use of the MentalPlus® digital game for assessment and rehabilitation of cognitive function after remission of the symptoms of COVID-19
- Where
- 2 sites in Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
COVID-19
COVID-19 Prevalence in UNIVI Geriatric Institutions: Epidemiological Study of Immunological Status With Rapid Serological Tests
To date, little information is available on the prevalence of Covid-19 and data are lacking on the proportion of patients, institutional residents and caregivers who have actually been exposed to SARS Cov-2.
- Trial name
- NCT04790994
- Where
- France
- Volunteers
- 1,145 people, healthy volunteers welcome
- Sponsor
- Centre Médical Porte Verte
SARS-CoV-2 Infection, Covid19
Tobacco Use and COVID-19 Incidence in the Finnish General Population
This is an observational study of participants in three general population health surveys (FinSote 2018, 2019, 2020) who are followed up until the incidence of SARS-CoV-2 infection or end of follow-up.
- Trial name
- Tobrisk-CoV (NCT04915781)
- Testing
- Not applicable, this is an observational study
- Where
- Finland
- Volunteers
- 60,872 people, healthy volunteers welcome
- Sponsor
- Finnish Institute for Health and Welfare
Covid-19, SARS Pneumonia
Assess the Safety and Immunogenicity of NDV-HXP-S Vaccine in Thailand
This study will be conducted in 2 phases. Phase 1 designed to evaluate safety, tolerability and immunogenicity COVID-19 vaccine (NDV-HXP-S) administered at different doses levels (1, 3, and 10 µg) without adjuvant, and at two…
- Conditions
- Covid-19, SARS Pneumonia, Pneumonia, Viral, Covid-19 Vaccine
- Trial name
- NCT04764422
- Testing
- Normal Saline, NDV-HXP-S vaccine
- Where
- Thailand
- Volunteers
- 455 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Covid19 Vaccine, Covid19
IntraDermal Versus Intramuscular Comirnaty® Efficacy Study
The 8-week, Prospective, Randomized controlled of IntraDermal administration of Comirnaty® 6 microgram compare to Intramuscular Comirnaty® 30 microgram by 28 days interval Efficacy Study in 4 groups of healthy volunteer ( 1…
- Trial name
- PRIDE (NCT05029245)
- Testing
- Comirnaty®
- Volunteers
- healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Pain, Healthy
Predicting Central Pain Among People With a Spinal Cord Injury by Evaluating Mechanisms Regulating Pain and Efficacy Testing of the TENS Apparatus
People with a Spinal Cord Injury can develop chronic pain within months of the injury. Up to 80% of the patients will develop chronic pain called "central pain" and describe the pain as: burning, stabbing, or "like electricity."…
- Trial name
- NCT01726881
- Testing
- Thermal stimulation, Mechanical stimulation, Transcutaneous Electrical Nerve Stimulator (TENS)
- Where
- Israel
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Pneumonia, Respiratory Failure
Pneumonia in the Intensive Care Unit (ICU) Setting
The purpose of this observational study is to collect prospective data on the occurrence of bacterial and viral pneumonia in the ICU setting.
- Trial name
- NCT02685930
- Testing
- Antibiotic de-escalation by ICU stewardship team with decreased exposure to broad spectrum antibiotics and shorter duration of therapy
- Where
- United States
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Covid19, Telogen Effluvium
COVID-19 Induced Telogen Effluvium
This study inquires about the development of Telogen effluvium following the SARS-CoV-2 infection
- Conditions
- Covid19, Telogen Effluvium, SARS-CoV Infection, Alopecia
- Trial name
- NCT04834102
- Testing
- Blood Tests
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
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