Clinical trials: Pneumonia, completed
Malnutrition, Diarrhea
Evaluation of Zinc and / or Micronutrient Supplementation on Intestinal Flora, Diarrheal Disease Burden, Intestinal Mucosal Integrity and Growth Among Children of Pakistan
Information on the mechanisms of zinc is still in developing phase. Ecological and biological implications of long term zinc supplementation at population level requires assessment.
- Conditions
- Malnutrition, Diarrhea, Pneumonia, Growth
- Trial name
- NCT00705445
- Testing
- Micronutrient Supplementation without Zinc, Micronutrient Supplementation with Zinc, Nutritional Counselling and Education
- Where
- 2 sites in Pakistan
- Volunteers
- 2,745 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Covid19, Symptoms and Signs
COVID-19 And Lingering Symptoms In Primary Care Patients
The ongoing corona virus disease 2019 (COVID-19) is a viral acute respiratory tract infection caused by server acute respiratory syndrom coronavirus typ 2 (SARS-CoV-2).
- Trial name
- CALIP (NCT04813731)
- Where
- 13 sites in Belgium, Denmark and 9 more
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Katarina Hedin
Severe Acute Respiratory Syndrome (SARS) Pneumonia, COVID-19 Pneumonia
GM-CSF Inhalation to Prevent ARDS in COVID-19 Pneumonia
To assess the safety and tolerability of inhaled molgramostim nebuliser solution in patients with COVID-19 pneumonia.
- Trial name
- GI-COVID (NCT04569877)
- Testing
- Molgramostim nebuliser solution
- Where
- 9 sites in Germany
- Volunteers
- 63 people
- Sponsor
- University of Giessen
COVID-19, Diabetes Mellitus
Insulin Regulation and Severity of Severe Acute Respiratory Syndrome COVID-19 Infection
The Coronavirus Disease of 2019 (COVID-19) pandemic has caused an international healthcare crisis and produced a large healthcare burden.
- Conditions
- COVID-19, Diabetes Mellitus, COVID-19 Pneumonia, COVID-19 Respiratory Infection
- Trial name
- NCT05897528
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 589 people
- Sponsor
- Arrowhead Regional Medical Center
Covid19
ACTIV-6: COVID-19 Study of Repurposed Medications
The purpose of this study is to evaluate the effectiveness of repurposed medications (study drug(s) in reducing symptoms of non-hospitalized participants with mild to moderate COVID-19.
- Trial name
- NCT04885530
- Testing
- Ivermectin, Fluvoxamine, Fluticasone
- Where
- 110 sites in United States
- Volunteers
- 10,956 people
- Sponsor
- Susanna Naggie, MD
Sickle Cell Disease, COVID-19
COVID-19 Vaccine Response in Sickle Cell Disease
The purpose of this study is to assess the antibody response to COVID-19 vaccination in a cohort of patients with sickle cell disease (SCD) and to assess vaccine and SCD related complications around the time of vaccination.
- Trial name
- NCT05139992
- Testing
- COVID-19 Vaccine
- Where
- 8 sites in United States
- Volunteers
- 59 people
- Sponsor
- ASH Research Collaborative
Coronavirus Infection
Inhaled Corticosteroid Treatment of COVID19 Patients With Pneumonia
Randomized, prospective, controlled open label clinical trial aimed at investigating if the addition of inhaled corticosteroids (budesonide) reduces treatment failure (defined as a composite variable by the initiation of…
- Trial name
- NCT04355637
- Testing
- Inhaled budesonide
- Where
- 14 sites in Argentina, Spain
- Volunteers
- 120 people
- Sponsor
- Sara Varea
Influenza
Pooled Analysis of Methodologically Harmonized Pragmatic Randomized Trials of High-Dose vs. Standard-Dose Influenza Vaccine Against Severe Clinical Outcomes
This prespecified analysis will pool the datasets from two pragmatic randomized trials evaluating the relative vaccine effectiveness of high-dose vs.
- Trial name
- FLUNITY-HD (NCT06506812)
- Testing
- High-Dose Influenza Vaccine, Standard-Dose Influenza Vaccine
- Where
- Denmark
- Volunteers
- 466,320 people
- Sponsor
- Tor Biering-Sørensen
Community-acquired Acute Lower Respiratory Infection
Advanced Diagnostics for Enhanced QUality of Antibiotic Prescription in Respiratory Tract Infections in Emergency Rooms
This study is a randomized controlled trial where participants are randomly assigned in a 1:1 ratio to either a rapid test group or a control group. Standard care is provided in the control group.
- Trial name
- ADEQUATE (NCT04781530)
- Testing
- BioFire FilmArray Respiratory Panel 2.1 plus (RP2.1plus)
- Where
- 6 sites in Germany, Greece and 3 more
- Volunteers
- 522 people
- Sponsor
- PENTA Foundation
Covid19, Measles Vaccine
Do Childhood Measles and DTaP Vaccination Decrease the Mortality Rate Caused by COVID-19 in OECD Countries?
Mortality rates caused by SARS CoV-2 differ between countries and this difference might be explained by several reasons. Childhood vaccination rate is thought to be one of them.
- Conditions
- Covid19, Measles Vaccine, Mortality
- Trial name
- NCT04468802
- Testing
- Case fatality rate
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
COVID-19 Pneumonia
RALE Versus CORADS/CT-Severity Score in COVID-19
Rationale Patients with severe coronavirus disease 2019 (COVID-19) frequently fulfill the criteria for acute respiratory distress syndrome (ARDS), with extensive and bilateral abnormalities on the chest radiography (CXR) and the…
- Trial name
- RALE-CORADS (NCT05047653)
- Testing
- RALE score vs. severity score
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
COVID-19
COVID-19 Variant Immunologic Landscape Trial (COVAIL Trial)
This phase 2 clinical trial will evaluate the safety and immunogenicity of additional doses of prototype and variant (alone or in combination) vaccine candidates in previously vaccinated participants with or without prior severe…
- Trial name
- NCT05289037
- Testing
- AS03, BNT162b2, BNT162b2 (B.1.1.529)
- Where
- 22 sites in United States
- Volunteers
- 1,270 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Community-acquired Pneumonia, Pneumonia
Clinical Trial of the Efficacy and Safety of Raphamin in Combined Treatment of Community-acquired Pneumonia
Multicenter double-blind placebo-controlled randomized in parallel groups clinical trial.
- Trial name
- NCT06263881
- Testing
- Raphamin
- Where
- 38 sites in Russia
- Volunteers
- 370 people
- Sponsor
- Materia Medica Holding
COVID - 19, Influenza A
Evaluation of COVID-19 and Flu A/B 3 in 1 Combo Rapid Test
This observational study aims to evaluate the diagnostic performance of an investigational Influenza A/B and COVID-19 test in patients presenting with signs and symptoms of respiratory infection.
- Conditions
- COVID - 19, Influenza A, Influenza B
- Trial name
- NCT07190131
- Testing
- Investigational Flu A/B And Covid-19 Diagnostic Test
- Where
- 15 sites in United States, Puerto Rico
- Volunteers
- 588 people
- Sponsor
- iHealth Labs inc
Ventilatory Defect, COVID-19
Visualizing Regional Lung Ventilation in Patients With Postacute-COVID-19
There is a lack of data of spontaneous breathing patients with post-COVID-19 syndrome (PCS) examined by Electrical impedance tomography (EIT). We compare 100 patients with PCS with 50 healthy probands.
- Conditions
- Ventilatory Defect, COVID-19, Post-acute COVID-19 Syndrome, Electric Impedance Tomography
- Trial name
- ViReVentPoCov (NCT05441657)
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Jan-Christoph Lewejohann
Pneumonia
Efficacy and Safety of Rheosorbilact® Solution for Infusion, in a Complex Therapy of Pneumonia
This study evaluates the efficacy and safety of Rheosorbilact®, solution for infusion ("Yuria-Pharm" LLC), in comparison with Ringer's Lactate, solution for infusion, in a complex therapy of pneumonia.
- Trial name
- NCT03824457
- Testing
- Rheosorbilact®, Ringer lactate
- Where
- 12 sites in Georgia, Kazakhstan and 4 more
- Volunteers
- 150 people
- Sponsor
- Yuria-Pharm
Asthma, Asthma Attack
Optimisation of ASthma In Those With Uncontrolled Symptoms (OASIS)
A digital tool, called ReferID has been developed to facilitate the review of asthma patients. It aims to assist in the identification of patients with uncontrolled and/or severe asthma and to ensure a timely referral to…
- Conditions
- Asthma, Asthma Attack, Asthma Persistent, Covid19
- Trial name
- OASIS (NCT04941001)
- Testing
- ReferID
- Where
- United Kingdom
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Pneumonia
Effectiveness Study of Integrative Treatment for Pediatric Pneumonia
The purpose of this study is to evaluate the effectiveness of traditional Chinese medicine for treatment of pediatric pneumonia. It is a multicenter randomized controlled trial.
- Trial name
- NCT02069665
- Testing
- Fuxiong San, Xiyanping injection, Ribavirin Injection
- Where
- 6 sites in China
- Volunteers
- 451 people
- Sponsor
- Liaoning University of Traditional Chinese Medicine
HIV Infections, Syphilis
Impact of COVID-19 on Provision and Uptake of Prevention of Mother-to-child Transmission of HIV Services in Zimbabwe
The COVID-19 pandemic and response are likely to lead to severe unintended consequences for the prevention of mother-to-child transmission (PMTCT) of HIV and syphilis.
- Trial name
- NCT04782739
- Testing
- None - Descriptive study
- Where
- 2 sites in Zimbabwe
- Volunteers
- 30 people
- Sponsor
- University of Zimbabwe
Coronavirus Infection, Covid19
Renal Biomarkers in AKI and COVID-19
Severe pneumoniae related to Coronavirus Disease (COVID-19), had a high in-hospital mortality; this condition are worst in subjects with acute kidney disease (AKI); conditioning increased mortality, days of assisted mechanical…
- Conditions
- Coronavirus Infection, Covid19, SARS (Severe Acute Respiratory Syndrome), AKI
- Trial name
- NCT04517630
- Testing
- urinary NGAL, TIMP-2, IGFBP7, IL-6, viral load and metabolomic
- Where
- Mexico
- Volunteers
- 51 people
- Sponsor
- Instituto Nacional de Enfermedades Respiratorias