Clinical trials: Pneumothorax Spontaneous Primary
Primary Spontaneous Pneumothorax
Which is Better Between Single Chest Tube and Multiple Tubes Drainage in Primary Spontaneous Pneumothorax
There was no evidence that the number of chest tube do effect to the recurrence of pneumothorax, which placed after thoracoscopic wedge resection together with mechanical pleurodesis.This study evaluates the efficacy of single…
- Trial name
- NCT04831554
- Testing
- single chest tube drainage
- Volunteers
- 200 people
- Sponsor
- Peking University Third Hospital
Spontaneous Pneumothorax, Idiopathic Pneumothorax
Thoracoscopy for Idiopathic Pneumothorax in Children
The goal of this retrospective study is to describe the outcomes of spontaneous idiopathic pneumothorax treated by thoracoscopy with pleural abrasion and blebectomy.
- Conditions
- Spontaneous Pneumothorax, Idiopathic Pneumothorax, Bleb Lung, Child, Only
- Trial name
- THOPED (NCT06734442)
- Testing
- Video-Assisted Thoracoscopy with blebectomy and pleural abrasion
- Where
- France
- Volunteers
- 23 people
- Sponsor
- University Hospital, Clermont-Ferrand
PCL Pleurodesis
PCL (Poly-ε-caprolactone) Mesh Pleurodesis
Recent advances in thoracoscopic surgery have made it a commonly used technique for treating spontaneous pneumothoraces and preventing recurrence.
- Trial name
- NCT03227978
- Testing
- PCL mesh pleurodesis
- Volunteers
- 10 people
- Sponsor
- National Taiwan University Hospital
Pneumothorax
Intrapleural Minocycline Following Simple Aspiration for Primary Spontaneous Pneumothorax
The optimal initial management of primary spontaneous pneumothorax (PSP) remains controversial. This study was conducted to evaluate the safety and efficacy of additional minocycline pleurodesis after successful aspiration of the…
- Trial name
- NCT00520221
- Where
- Taiwan
- Volunteers
- 64 people
- Sponsor
- National Taiwan University Hospital
Pneumothorax, Pleurodesis
Improving Primary Spontaneous Pneumothorax (PSP) Treatment Techniques in VATS
The purpose of this study is to: 1. Evaluate the validity of using abnormal characteristics of the pneumothorax line, as evaluated from chest X-ray film, as the operative indications for video-assisted thoracic surgery (VATS) on…
- Trial name
- NCT01463553
- Testing
- VATS pleurodesis
- Where
- China
- Volunteers
- 320 people
- Sponsor
- Beijing Haidian Hospital
Pneumothorax
Comparison of Exsufflation Versus Drainage in Primary Spontaneous Pneumothorax
Management of primary spontaneous pneumothorax (PSP) remains unclear. Primary therapeutic goals for PSP include removal of air from the pleural space an prevention of recurrences.
- Trial name
- EXPRED (NCT01008228)
- Testing
- exsufflation, thoracic tube drainage
- Where
- 24 sites in France
- Volunteers
- 402 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Primary Spontaneous Pneumothorax
Comparative Study of Nonintubated Anesthesia Versus Intubated General Anesthesia in Single Port Thoracoscopic Bullectomy
Investigators compared the patients' subjective postoperative symptoms and complications between the double lumen endotracheal intubated patients under general anesthesia and non-intubated patients under sedation and local…
- Trial name
- NCT02109510
- Testing
- nonintubated sedation anesthesia with dexmedetomidine IV, ketamine IV and intercostal nerve block with lidocaine infiltration, intubated general anesthesia with propofol IV, rocuronium IV ,sevoflurane and N2O gas, single port thoracoscopic bullectomy
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Korea University
Pneumothorax, Primary Spontaneous, VATS
Optimal Postoperative Chest Tube and Pain Management in Patients Surgically Treated for Primary Spontaneous Pneumothorax (Pneumotrial)
Guidelines lack high quality evidence on optimal postoperative chest tube and pain management after surgery for primary spontaneous pneumothorax (PSP).
- Conditions
- Pneumothorax, Primary Spontaneous, VATS, Pain, Postoperative, Locoregional Anaesthesia
- Trial name
- NCT06053476
- Testing
- Thoracic epidural analgesia, Single-shot paravertebral block, Late chest tube removal
- Where
- Netherlands
- Volunteers
- 366 people
- Sponsor
- Maxima Medical Center
Primary Spontaneous Pneumothorax
Early Chest Tube Removal After Surgery for Primary Spontaneous Pneumothorax: A Randomized Controlled Trial
Video-assisted thoracoscopic surgery (VATS) with blebectomy/wedge resection plus pleurodesis is the standard of care for recurrent primary spontaneous pneumothorax (PSP) or, in certain instances, after the first episode.
- Trial name
- NCT06411431
- Testing
- Early Chest Tube Removal, Standard Chest Tube Removal, Apical Chest Tube
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Swedish Medical Center
Malignant Pleural Effusions, Recurrent Pleural Effusions
A Comparative Study of the Safety and Efficacy of Face Talc Slurry and Iodopovidone for Pleurodesis
Pleurodesis is a technique used to fuse the two layers of the lining over the lung. This is done to get rid of collections of fluid or air in this space.
- Conditions
- Malignant Pleural Effusions, Recurrent Pleural Effusions, Primary Spontaneous Pneumothorax, Secondary Spontaneous Pneumothorax
- Trial name
- NCT00430664
- Testing
- Pleurodesis with either talc or iodopovidone
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Pneumothorax
Intrapleural Minocycline After Aspiration of Spontaneous Pneumothorax
The estimated recurrence rate of primary spontaneous pneumothorax is 23-50% after the first episode, and the optimal treatment remains unknown.
- Trial name
- NCT00839553
- Testing
- Intrapleural Minocycline application
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Far Eastern Memorial Hospital
Pneumothorax
Primary Versus Delayed Surgical Therapy for Pediatric Spontaneous Pneumothorax
The purpose of this study is to compare the effectiveness of two treatment strategies--delayed versus immediate surgery-- for children with primary spontaneous pneumothorax (collapse of the lung).
- Trial name
- NCT02449980
- Testing
- Primary Surgery Group, Initial Non-operative management
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Baylor College of Medicine
Primary Spontaneous Pneumothorax, Pleural Disease
Study Designed to Optimize the Treatment of Primary Pneumothorax
Knowledge about incidence, risk factors and genetic predispositions of primary spontaneous pneumothorax in young adults is very limited, and treatment has also been controversial.The Aim of this study is to optimize the…
- Trial name
- TOPP (NCT02866305)
- Testing
- VATS bullectomy and mechanical pleuradesis., Chest tube insertion, Epidural
- Where
- 3 sites in Denmark
- Volunteers
- 300 people
- Sponsor
- Odense University Hospital
Pneumothorax Spontaneous Primary
Outpatient Management of Primary Spontaneous Pneumothorax: Pigtail Catheter With Unidirectional Valve vs. Exsufflation, Randomized Prospective Study
The management of large spontaneous pneumothorax is not consensual. Current practice involves placement of a Fuhrman catheter connected to a one-way valve, with outpatient monitoring in pneumology consultation.
- Trial name
- PNEUM-AMBU (NCT03691480)
- Testing
- Fuhrman catheter insertion, Three-way stopcock open, Manual aspiration
- Where
- 5 sites in France
- Volunteers
- 148 people
- Sponsor
- Rennes University Hospital
Thoracic Surgical Procedures
Thoracoscopic Bullectomy Versus Thoracoscopic Bullectomy With Pleurodesis in Primary Spontaneous Pneumothorax
The exact pathogenesis of PSP is controversial. A few theories has been proposed contributing to the pathogenesity of the PSP as emphysematous like changes (ELCs) which lead to the formation and rupture of the lung bullae or…
- Trial name
- NCT03943069
- Testing
- Thoracoscopic bullectomy alone, Thoracoscopic bullectomy with pleurodesis
- Where
- Saudi Arabia
- Volunteers
- 232 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Primary Spontaneous Pneumothorax
Effect of Tetracycline Pleurodesis on Prevention of Primary Spontaneous Pneumothorax Recurrence
Primary spontaneous pneumothorax (PSP) defines as presence of air in chest cavity occurs most commonly in young, tall, and smoker men without underlying lung disease. Trends for PSP treatment tend toward more invasive procedures.
- Trial name
- NCT03634605
- Testing
- Chemical pleurodesis, Tetracycline Topical Ointment, Normal saline
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Isfahan University of Medical Sciences
Primary Spontaneous Pneumothorax
Efficacy of the Additional Mechanical Pleurodesis for Surgical Management of Primary Spontaneous Pneumothorax
For the definite treatment of primary spontaneous pneumothorax(PSP), thoracoscopic bleb obliteration with pleural adhesive procedure is generally accepted as a standard.
- Trial name
- NCT00615849
- Testing
- thoracoscopic surgery
- Where
- South Korea
- Volunteers
- 1,440 people
- Sponsor
- Seoul National University Bundang Hospital
Primary Spontaneous Pneumothorax
Autologous Blood Patch for Primary Spontaneous Pneumothorax
The purpose of this study is to show that treatment with prophylactic autologous blood patch (ABP) after management of primary spontaneous pneumothorax (PSP) is feasible, reduces the incidence of prolonged air leaks, and reduces…
- Trial name
- NCT06088901
- Testing
- Autologous Blood Patch
- Where
- United States
- Sponsor
- Rush University Medical Center
Pneumothorax
Chest Tube Drainage or Thoracoscopic Surgery for Failed Aspiration of Spontaneous Pneumothorax
We hypothesize that VATS is more effective than CTD for management of primary spontaneous pneumothorax with aspiration failure. To this end, we will compare two groups of patients who had experienced unsuccessful aspiration of…
- Trial name
- NCT00713362
- Testing
- Video-assisted thoracoscopic surgery, chest tube drainage
- Where
- 2 sites in Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Pneumothorax Spontaneous Primary, Pneumothorax Spontaneous Secondary
Comparison of Talc Slurry Versus Talc Insufflation: A Study on Effectiveness, Safety, and Hospital Outcomes in Pleurodesis
Pleural effusion is characterized by the accumulation of fluid in the pleural space, which typically contains about 10-20 mL of pleural fluid that is crucial for the movement of the lungs against the chest wall.
- Conditions
- Pneumothorax Spontaneous Primary, Pneumothorax Spontaneous Secondary, Pleural Effusion, Malignant, Pleurodesis
- Trial name
- NCT07167992
- Testing
- Pleurodesis
- Where
- Pakistan
- Volunteers
- 160 people
- Sponsor
- University of Health Sciences Lahore