Clinical trials: Pocket, Periodontal
Periodontitis, Periodontal Pocket
Treatment of Advanced Periodontitis With a Chitosan Brush and a Chitosan Gel
In the here suggested study, the aim is to test non-surgical treatment of advanced periodontal disease with a chitosan brush with or without chitosan gel in patients with advanced periodontal disease having responded poorly to a…
- Conditions
- Periodontitis, Periodontal Pocket, Periodontal Diseases, Periodontal Inflammation
- Trial name
- Chitosangel (NCT05773911)
- Testing
- 4% chitosan gel (pH 3.48)., Reciprocal Chitosan brush
- Where
- Norway
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Caspar Wohlfahrt
Diabete Type 2
Pocket-X Gel Non-surgical Periodontal Therapy
Evaluate from a clinical and microbiological point of view the effect of an adjunctive therapy based on a thermal-gelling device Pocket-X® Gel (Hyaluronic acid, Poloxamer, 2-Phenoxyethanol, Octedine HCL, Water), in the…
- Trial name
- DEFECT_PERIO (NCT07372677)
- Testing
- Gel therapy after non surgical therapy
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Chronic Periodontitis (Disorder), Periodontitis
i-PRF & Root Surface Biomodification
This study is designed to evaluate a new method to improve healing in patients with gum disease (periodontitis). A total of 42 adults with gum pockets deeper than 5 millimeters will take part.
- Trial name
- iPRF-Perio (NCT07207668)
- Testing
- Open Flap Debridement (OFD), 24% EDTA Root Conditioning, Injectable Platelet-Rich Fibrin (i-PRF)
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Halil Ata BIÇAKÇIOGLU
Periodontal Diseases
Clinical Relevance of Different Time of Periodontal Re-evaluation
Treatment of periodontitis follows an incremental step approach. The results after step 1 (Oral Hygiene Instruction and Professional Mechanical Plaque Removal) and 2 (subgingival instrumentation) are re-evaluated in order to…
- Trial name
- NCT06086821
- Testing
- Periodontal Re-Evaluation
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Florence
Periodontal Bone Loss, Periodontal Pocket
Treatment of Intraosseous Periodontal Defects With Amelogenins
The aim of the present investigation will be evaluate the healing of periodontal intraosseous defects following Minimally Invasive Non Surgical Debridement (MINSD) and application of amelogenins, compared to MINSD alone.
- Trial name
- NCT05315804
- Testing
- MINSD and amelogenins, MINSD
- Where
- Italy
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Federico II University
Periodontal Attachment Loss, Periodontal Pocket
Dietary Intakes and Periodontal Health: A Follow-Up Study
A previous study, on which this study is based, found that a diet higher in fruits and vegetables, beta-carotene, vitamin C, alpha-tocopherol, and fish oils (specifically eicosapentaenoic acid (EPA) and docosahexaenoic acid…
- Trial name
- NCT03073174
- Where
- Canada
- Volunteers
- 43 people
- Sponsor
- Brock University
Periodontal Pocket, Tooth,Non Vital
Chlorhexidine Intracanal Medicament in Periodontal Healing in Concomitant Endo Perio Lesion With Communication
The aim of this prospective randomized controlled clinical trial is to evaluate the effectiveness of chlorhexidine intracanal medicament along with periodontal treatment in concomitant endodontic periodontal lesions with…
- Trial name
- NCT02627326
- Testing
- open flap debridement
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Periodontitis
Intra-pocket Application of Tea Tree Oil Gel in the Treatment of Stage-2 Periodontitis
This study aimed to assess clinically and biochemically the effect of intrapocket application of tea tree oil (TTO) gel adjunctive to SRP in the management of stage 2(moderate) periodontitis and to correlate the biochemical…
- Trial name
- NCT04769271
- Testing
- Scaling and Root Planing, Scaling and Root Planing with tea tree oil
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Periodontal Pocket, Periodontal Diseases
Periodontal Granulation Tissue Preservation in Surgical Periodontitis Treatment
The objective of this study will be to evaluate a new protocol for the surgical treatment of periodontal disease with two novelties: to make a single incision in the midline of the interproximal area to respect the vascular…
- Conditions
- Periodontal Pocket, Periodontal Diseases, Periodontal Bone Loss
- Trial name
- NCT05533528
- Testing
- periodontal surgery
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Universidad de Murcia
Periodontal Diseases, Wound Heal
Hyaluronic Acid and Polynucleotides for Supra-bony Defects
The goal of this pilot study is to describe the early wound healing molecular events and the vascularization pattern associated with the treatment of supra-bony defects with access flap alone or in association with a combined…
- Conditions
- Periodontal Diseases, Wound Heal, Periodontal Inflammation, Periodontal Pocket
- Trial name
- NCT06309719
- Testing
- Periodontal Access Flap (AF) + Combined Formulation of Hyaluronic acid and Polydeoxyribonucleotides (PNHA), Periodontal Access Flap (AF)
- Where
- 2 sites in United Kingdom
- Volunteers
- 24 people
- Sponsor
- Queen Mary University of London
Chronic Periodontitis
Clinical Trial of PeriZone PerioPatch in Subjects With Chronic Periodontitis
The purpose of this study is to determine if a topical, adhesive patch (PeriZone PerioPatch) applied to the gums after a deep tooth cleaning (scaling and root planing) reduces the signs of advanced gum disease (chronic…
- Trial name
- NCT01808703
- Testing
- PeriZone PerioPatch, Scaling and root planing alone
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- MIS Implant Technologies, Ltd
Periodontal Pocket, Periodontitis
Multicenter Study on the Use of a Collagen-based Hydrogel for the Treatment of 153 Periodontal Pockets in 38 Adults With Generalized Stage III Periodontitis
This is a prospective, observational, multicenter study designed to evaluate the real-world efficacy and safety of H42®, a collagen hydrogel, in the treatment of periodontal pockets.
- Trial name
- NCT07592377
- Testing
- H42® Collagen Hydrogel for the non-surgical treatment of periodontal pockets
- Where
- 2 sites in Italy
- Volunteers
- 38 people
- Sponsor
- Bioteck S.p.A.
Periodontitis
Efficacy of Guided Biofilm Therapy (GBT) for Treatment of Deep Periodontal Pockets.
the aim of the study is to evaluate the efficacy of guided biofilm therapy (GBT) for treatment of deep periodontal pockets. the objectives are 1- To compare the change in the clinical periodontal parameters and microbiological…
- Trial name
- NCT06319261
- Testing
- guided biofilm therapy, root surface debridement
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Periodontal Pocket
Efficacy of Locally Delivered Tea Tree Oil Gel as an Adjunct to Non-Surgical Periodontal Management
Periodontitis is an inflammatory disease of the teeth's supporting tissues caused by specific microbes or groups of microorganisms that contributes to gradual deterioration of the periodontal ligament and alveolar bone, leading…
- Trial name
- NCT05803031
- Testing
- Melaleuca Alternifolia Oil, Non-surgical periodontal debridement
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Periodontitis, Periodontitis Stage III
Diode Laser-Assisted Periodontal Therapy Enhances Clinical Outcomes for Deep Periodontal Pockets in Smokers
This study investigated the adjunctive effects of diode laser therapy in smokers with severe periodontitis. Thirty-three patients were randomized to non-surgical periodontal therapy (SRP) with or without diode laser.
- Conditions
- Periodontitis, Periodontitis Stage III, Periodontal Disease, Diode Laser Therapy
- Trial name
- NCT07213752
- Testing
- Diode Laser Application in Deep Periodontal Pockets, Professional Mechanical Plaque Removal, Scaling and Root Planing
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Periodontal Pocket
Concentrated Platelet Rich Fibrin (C-PRF) as Adjunct to Non-surgical Periodontal Therapy
The current study is a prospective randomised split mouth study to evaluate the effect of concentrated Platelet Rich Fibrin as an adjunct to the scaling and root planing
- Trial name
- NCT05958147
- Testing
- C-PRF
- Where
- India
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Periodontal Pocket, Impacted Third Molar Tooth
Evaluation of Two Different Grafting Techniques After Mandibular Impacted Third Molar Surgery
This study evaluates the effectiveness of using Mineralized Plasmatic Matrix and β-tricalcium phosphate that placed to extraction socket as a graft material in terms of periodontal damage occurred in the distal aspect of the…
- Conditions
- Periodontal Pocket, Impacted Third Molar Tooth, Impacted Teeth With Abnormal Position
- Trial name
- NCT04366635
- Testing
- Impacted third molar surgery, Application of mineralised plasmatic matrix, Application of β-tricalcium phosphate
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Konya Necmettin Erbakan Üniversitesi
Periodontitis, Periodontal Diseases
Clinical and Radiographic Evaluation of PPF With or Without NCHA Bone in Treatment of Intrabony Defects
This study is meant to assess clinically and radiographically the possible predictable results regarding the use of nanocrystalline hydroxyapatite bone graft substitute together with papilla preservation flap versus papilla…
- Conditions
- Periodontitis, Periodontal Diseases, Periodontal Pocket, Intrabony Periodontal Defect
- Trial name
- NCT03588507
- Testing
- PPF+NCHA bone graft substitute
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontitis
The Effect of Locally Delivered Ciclosporin as an Adjunct to Healing After Treatment of Periodontal Pockets
The main purpose of the trial is to investigate the effect of locally delivered ciclosporin as an adjunct to non-surgical mechanical debridement in the treatment of chronic periodontitis and to compare it to mechanical…
- Trial name
- NCT02366585
- Testing
- Ciclosporin
- Where
- Sweden
- Volunteers
- 23 people
- Sponsor
- PerioC Limited
Anxiety Disorders, Oral Disease
Effect of Trait Anxiety in Women on Oral Health Status and Oral Health Care-Seeking Behavior
Trait anxiety is the tendency of an individual to perceive environmental stimuli such as different events and situations as threatening; it's stable and reflects how an individual generally feels.
- Conditions
- Anxiety Disorders, Oral Disease, Periodontal Diseases, Periodontal Attachment Loss
- Trial name
- NCT04274855
- Where
- Egypt
- Volunteers
- 451 people, healthy volunteers welcome
- Sponsor
- Ain Shams University