Clinical trials: Point-of-Care Systems
HIV/AIDS
Reaching 90% HIV Suppression: The Role of POC Viral Load Monitoring in Nigeria
The UNAIDS 90-90-90 goals represents an ambitious strategy to end the acquired immunodeficiency syndrome (AIDS) epidemic by 2020 [UNAIDS, 2015].
- Trial name
- POC (NCT03533868)
- Testing
- Point-of-care viral load monitoring test
- Where
- 2 sites in Nigeria
- Volunteers
- 543 people
- Sponsor
- Harvard School of Public Health (HSPH)
Point of Care Ultrasound
A Novel Training Simulator for Portable Ultrasound Identification of Incorrect Newborn Endotracheal Tube Placement
First seconds after birth, new born baby go through physiologic changes to successfully adjust to the external environment specially establishment of independent respiration.
- Trial name
- NCT03533218
- Testing
- Point of care Ultrasound machine
- Where
- Pakistan
- Volunteers
- 292 people
- Sponsor
- Aga Khan University
Coagulation Disorder
INR Comparison Testing in Cardiac Surgery
The investigator is testing blood samples to compare the results of two different techniques. Since blood loss and the need for blood transfusions continue to be major problems after heart surgery and other types of surgery, the…
- Trial name
- NCT03267823
- Testing
- International Normal Ratio (INR)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Miami
Pneumothorax Iatrogenic Postprocedural
Clinical Value of Routine Chest Radiography and Point-of-Care Lung Ultrasound Following Ambulatory Thoracic Sympathectomy
The goal of this observational study is to find out whether routine chest X-rays after surgery actually change patient care, and whether lung ultrasound could be a suitable alternative for detecting important postoperative…
- Trial name
- LUNG_US_SIMP (NCT07854340)
- Where
- Chile
- Volunteers
- 200 people
- Sponsor
- Clinica Alemana de Santiago
Cerebral Hemorrhage
Emergency Management of Spontaneous Intracerebral Haemorrhage - Biomarkers
The bio-markers substudy of EsICH is designed to recruit patients with acute (first 8h) spontaneous intracerebral hemorrhage and assess a series of biological parameters (CBC, glucose, cholesterol, LDL cholesterol, triglycerides)…
- Trial name
- EsICH (NCT02935985)
- Testing
- Point-of-care bio-markers (cTnI, hsCRP, D-Dimer) and biological parameters (CBC, glucose, cholesterol, LDL cholesterol, triglycerides, fibrinogen)
- Where
- 2 sites in Romania
- Volunteers
- 39 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Educational Problems
Point-of-Care Ultrasound (PoCUS) Teleeducation Curriculum for Hospital-at-home Care
Since July 2024, the National Health Insurance Administration (NHIA) has been implementing a pilot Hospital-at-Home (HAH) Acute Care Program to curb hospital admissions.
- Trial name
- NCT07182162
- Testing
- Remote supervision + simulation
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Crohn Disease of Small Intestine
Implementation of Point Of Care UltraSound in the Assessment of Crohn's Disease -The POCUS Study
1. Explore Stakeholder perceptions of POCUS service development and implementation in the NHS in an interview Sub-study. We will assess whether stakeholders: Recognise the potential of POCUS for the management of small bowel CD…
- Trial name
- POCUS (NCT07157436)
- Testing
- Non-interventional study
- Where
- United Kingdom
- Volunteers
- 4 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Hypotension
Ultrasound in Undifferentiated Hypotension
Background Symptomatic undifferentiated hypotension represents a negative prognostic factor and the strongest predictor of in-hospital mortality.
- Trial name
- US-UHP (NCT01572571)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- San Luigi Gonzaga Hospital
Sepsis
Evaluation of Immunoassay Measurements of Pancreatic Stone Protein Performed on abioSCOPE® Device With the PSP Assay on ICU Patients at Risk of Sepsis as an Aid in Identifying Sepsis
This is a multicenter, prospective, biomarker-result-blinded observational study evaluating immunoassay measurements of pancreatic stone protein (PSP) performed on Abionic's abioSCOPE device with the PSP assay on ICU patients at…
- Trial name
- NCT04105699
- Testing
- Blood sampling
- Where
- 5 sites in United States
- Volunteers
- 544 people
- Sponsor
- Abionic SA
Syphilis, HIV Infections
Spotting Syphilis: A Dual Point-of-Care Syphilis Screening Initiative in a Low-Resource Healthcare Setting
The purpose of this study is to determine if a strategy utilizing the Chembio HIV/syphilis rapid point-of-care (POC) test for diagnosis of HIV and syphilis in pregnant women attending prenatal clinics in Guatemala will increase…
- Trial name
- NCT07498153
- Testing
- Chembio HIV/Syphilis rapid POC test
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- The University of Texas Health Science Center, Houston
Pulmonary Tuberculosis, Tuberculosis Diagnosis
Diagnostic Accuracy of CAD4TB and C-reactive Protein Assay as Triage Tests for Pulmonary Tuberculosis
In the TB TRIAGE+ ACCURACY study, the accuracy of the following products will be determined: CAD4TB (Delft Imaging System, NL), a digital chest x-ray analysis software Afinion CRP assay (Alere Afinion, USA), which detects a…
- Conditions
- Pulmonary Tuberculosis, Tuberculosis Diagnosis, Covid-19, HIV
- Trial name
- TB TRIAGE+ (NCT04666311)
- Testing
- Accuracy of CAD4TB and Afinion CRP assay for pulmonary TB, CAD4COVID+WBC and COVID-19 RDT for SARS-CoV-2 infection
- Where
- 2 sites in Lesotho, South Africa
- Volunteers
- 1,400 people
- Sponsor
- Klaus Reither
Oral Cavity Squamous Cell Carcinoma, Oropharynx Squamous Cell Carcinoma
Saliva-based Detection of CD44
The purpose of this study is to test the ability of OncAlert™ to screen for cancer and the reappearance of cancer. OncAlert™ was developed by Vigilant Biosciences, a collaborator in this research study.
- Conditions
- Oral Cavity Squamous Cell Carcinoma, Oropharynx Squamous Cell Carcinoma, Squamous Cell Carcinoma of the Oropharynx, Squamous Cell Carcinoma of the Head and Neck
- Trial name
- Detect 44 (NCT03148665)
- Testing
- OncAlert
- Where
- 4 sites in United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Joseph Califano
Rattlesnake Bite (Diagnosis)
Point-of-care Ultrasound in the Assessment of Snake Bite
Early identification of tissue injury from a rattlesnake bite is critical to prevent complications and reduce health care costs.
- Trial name
- NCT04188899
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Arizona
Subacromial Impingement Syndrome, Carpal Tunnel Syndrome (CTS)
Clinical and Economic Evaluation of Point-of-care Ultrasound-guided Infiltration for Subacromial and Carpal Tunnel Syndromes in Primary Care: a Cluster-randomized Study Protocol.
The aim of this clinical trial is to determine whether point-of-care ultrasound-guided corticosteroid injection is more effective than conventional injection guided by anatomical landmarks or standard oral medication for patients…
- Conditions
- Subacromial Impingement Syndrome, Carpal Tunnel Syndrome (CTS), Pain Management
- Trial name
- Q-EPICAP (NCT07692516)
- Testing
- Standard Oral Treatment, Conventional Infiltration, Ultrasound-Guided Infiltration
- Where
- Spain
- Volunteers
- 225 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Colles Fracture, Point of Care Ultrasound
Ultrasound Assisted Distal Radius Fracture Reduction
PURPOSE: to evaluate the utility of bedside ultrasound performed by emergency physicians in the evaluation and reduction of colles fractures as compared with traditional pre and post reduction radiographs.
- Conditions
- Colles Fracture, Point of Care Ultrasound, Emergency Ultrasound
- Trial name
- NCT01561573
- Testing
- Point of care ultrasound
- Where
- 8 sites in Canada
- Volunteers
- 136 people
- Sponsor
- University of British Columbia
Cardiac Surgical Procedures, Hemodynamics
Structured Hemodynamic Assessment to Guide Care After Cardiac Surgery
This multicenter pilot randomized controlled trial will evaluate whether providing treating physicians with a structured hemodynamic assessment influences care after cardiac surgery.
- Conditions
- Cardiac Surgical Procedures, Hemodynamics, Fluid Therapy, Acute Kidney Injury
- Trial name
- UTF-in-CVICU (NCT07792707)
- Testing
- Expert Report of a Structured Hemodynamic Assessment, Standard Care (in control arm)
- Where
- 2 sites in Canada
- Volunteers
- 75 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Coronavirus, Respiratory Failure
Prognostic Value of Point of Care Cardiac and Lung Ultrasound in COVID-19
This is a protocol-driven observational study of lung ultrasound and focused echocardiography images obtained in the Emergency Department (ED) and Intensive Care Unit (ICU) settings as a part of existing standard of care.
- Trial name
- CLUSCO (NCT04379544)
- Testing
- Observation only
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- University of Pennsylvania
Trauma, Burns
Point of Care Testing of Cholinesterase Activity During Burn- and Polytrauma
Goal of this study is to measure serum cholinesterase activity in patients with traumatic and/or burns injury admitted to the emergency room by using point-of- care-test system (POCT).
- Trial name
- POCCET (NCT02691650)
- Where
- Germany
- Volunteers
- 85 people
- Sponsor
- University Hospital Heidelberg
Critical Laboratory Values, Drug Laboratory Interactions
Effect of an Automated Paging System on Response to Critical Laboratory Values
Patients in hospitals may develop serious problems that are detected by blood tests. It is very important for the physicians to be notified of these abnormal blood tests as soon as possible.
- Conditions
- Critical Laboratory Values, Drug Laboratory Interactions, Drug Drug Interactions
- Trial name
- NCT00469924
- Testing
- Real Time Clinical Alerting
- Where
- Canada
- Volunteers
- 271 people
- Sponsor
- Sunnybrook Health Sciences Centre
Risk Reduction
Urine Tenofovir Point-of-care Test to Identify Patients in Need of ART Adherence Support (UTRA Study)
ART is given to people living with HIV in order to suppress the virus, resulting in improved health for the individual and decreased transmission of the virus to others. Success of ART is dependent on adherence.
- Trial name
- NCT05333679
- Testing
- UTRA, UTRA feedback
- Where
- South Africa
- Volunteers
- 200 people
- Sponsor
- University of California, San Francisco
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