Clinical trials: Point-of-Care Systems
COVID-19 Respiratory Infection
COVID-19 Novel Molecular Point of Care Diagnostics Evaluation
Point estimates of sensitivity and specificity of molecular POC platforms for SARS-CoV-2, with 95% confidence intervals, using RT-PCR as reference standard.
- Trial name
- NCT06055218
- Where
- 3 sites in Switzerland, Uganda and 1 more
- Volunteers
- 600 people
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Renal Colic
Renal Colic Fast Track Pathway in the Emergency Department.
Validation of a high-resolution, fast track pathway that combines the use of laboratory tests at the Point-of-Care Testing (POCT) and Point-of-Care ultrasound (POCUS) versus the classical pathway, in which blood samples are sent…
- Trial name
- NCT03706404
- Testing
- Point-of-Care ultrasound and testing
- Where
- Spain
- Volunteers
- 128 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario la Paz
Cirrhosis, Liver, Acute-On-Chronic Liver Failure
Point-of-Care Echocardiography to Assess Impact of Dynamic Cardiac Function, Renal and Cardiac Biomarkers in Cirrhosis With Refractory Ascites
Point-of-care echocardiography (POC-Echo) is used to determine left ventricular systolic and diastolic dysfunction (LVDD), inferior vena cava (IVC) dynamics and volume status in cirrhosis and Acute-on-chronic liver failure ACLF…
- Conditions
- Cirrhosis, Liver, Acute-On-Chronic Liver Failure, Refractory Ascites, Ascites
- Trial name
- NCT05700708
- Testing
- Echocardiographic assessment
- Where
- India
- Volunteers
- 80 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Infection, Bacterial, Antibiotic Side Effect
Medical Device (MD) Derived Pharmacokinetic (PK) Parameters for Vancomycin (MD-PK)
Getting the right dose of antibiotic promptly is an important part of treating infections. Unfortunately, when an infection is severe (sepsis) the body changes how it processes antibiotics.
- Conditions
- Infection, Bacterial, Antibiotic Side Effect, Antibiotic Resistant Infection, Sepsis
- Trial name
- MD-PK (NCT05950984)
- Testing
- Drug Infusion Pump Monitoring
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- St George's, University of London
Micronutrient Levels
VITAmin and Micronutrient Testing: Acceptability and SCOPE of Point-of-care Device
Childhood obesity is a global health crisis with 1.2 million children in England severely obese, predisposing them to multiple health risks which decrease lifespan and compromise health.
- Trial name
- VITASCOPE (NCT06882421)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
HIV Infections, Hiv
Diagnosis of HIV and Early Antiretroviral Therapy Initiation Among HIV-1 Infected Infants
The purpose of the study is to test the effect of the Alere™ q HIV-1/2 Detect (diagnostic assay) on uptake of HIV testing among HIV-exposed infants and young children, and health outcomes for HIV-infected infants and young…
- Trial name
- CDC Detect (NCT03133728)
- Testing
- Alere Q Testing
- Where
- 6 sites in Zambia
- Volunteers
- 1,682 people
- Sponsor
- University of Alabama at Birmingham
Aconite Poisoning
Development of an Aptamer-based Lateral Flow Device for Point-of-care Detection of Toxic Chinese Medicine Herbs (ALPTH Project)
Aconitine and related alkaloids are potent cardiotoxins and neurotoxins found in the Aconitum species used in traditional Chinese medicine (TCM), such as 'Chuanwu', 'Caowu' and 'Fuzi'.
- Trial name
- ALPTH1 (NCT07456592)
- Where
- 2 sites in Hong Kong
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Dry Eye
Point of Care Test of LTA Level in Tear Fluid, Measured With a POCT Test, in DE Patients Following IPL Treatment
To quantify and compare tear levels of Intense pulsed light (IPL) and traditional dry eye clinical tests in dry eye patients before and after Intense pulsed light (IPL) treatment.
- Trial name
- NCT06269237
- Testing
- M22
- Volunteers
- 30 people
- Sponsor
- He Eye Hospital
Cardiology, Acute Coronary Syndrome
Echocardiography by Non-cardiologist in Early Management of Patients With Chest Pain
The aim of the study is to find out the benefit of echocardiography, which is performed by a physican without a cardiological or radiological specialty.
- Conditions
- Cardiology, Acute Coronary Syndrome, Echocardiography
- Trial name
- ENDEMIC (NCT05306730)
- Testing
- ECHOcardiography, Point-of-Care UZ
- Volunteers
- 430 people
- Sponsor
- University of Defence, Faculty of Military Health Sciences
Pneumonia, Bacterial, Viral Infection
Diagnostic and Prognostic Biomarkers for Childhood Bacterial Pneumonia
Clinical pneumonia is a leading cause of pediatric hospitalization. The etiology is generally bacterial or viral. Prompt and optimal treatment of pneumonia is critical to reduce mortality.
- Conditions
- Pneumonia, Bacterial, Viral Infection, Clinical Pneumonia, Plasmodium Falciparum Malaria
- Trial name
- NCT03996967
- Where
- 3 sites in United States, Netherlands and 1 more
- Volunteers
- 837 people
- Sponsor
- Boston University
Vaginitis, Bacterial Vaginosis
Point of Care Diagnosis of Vaginal Infections
Vaginal infections are a common gynecologic issue and may cause significant symptoms and discomfort for individuals. Point of care tests are used to diagnose infections in the office, with an advantage of quick diagnosis and…
- Conditions
- Vaginitis, Bacterial Vaginosis, Yeast Vaginitis, Trichomonas Vaginitis
- Trial name
- PAT (NCT06438575)
- Testing
- Xpert® Xpress MVP test, Usual Care
- Where
- United States
- Volunteers
- 351 people
- Sponsor
- Sharon L Hillier
Surgery
The ImPreSS Trial: Pharmacogenomic Decision Making at Time of Surgery
The study is enrolling adults who are scheduled for either inpatient or outpatient elective surgical procedures at The University of Chicago.
- Trial name
- NCT03729180
- Testing
- Routine Elective Surgery- In patient or out patient elective surgery, Blood test for genetic testing, Drug-genetic Profile
- Where
- United States
- Volunteers
- 1,900 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Fracture Tibia, Fracture Femur
3D Planned Surgery of Acute Fractures Performed With 3D Guides Printed at the Point of Care
The aim of the study is to assess the accuracy of fracture reduction performed with surgical guides designed and 3D printed at the point of care in comminuted fractures of femur- and tibia-shaft.
- Conditions
- Fracture Tibia, Fracture Femur, Fracture, Comminuted
- Trial name
- 3DFRG (NCT05741892)
- Testing
- Fracture reposition with 3D printed patient specific repositions guides
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Ovarian Cancer, Endometrial Cancer
Predictors of Ovarian Cancer and Endometrial Cancer for Artificial-Intelligence-Based Screening Tools
The goal of this observational study is to explore the possible associated factors of ovarian cancer and endometrial cancer in Indonesia and develop screening tools that could predict the risk of both types of cancer The specific…
- Conditions
- Ovarian Cancer, Endometrial Cancer, Endometrial Hyperplasia
- Trial name
- NCT05697601
- Testing
- Artificial-Intelligence Based Screening Tools, Pathology analysis
- Where
- Indonesia
- Volunteers
- 2,905 people, healthy volunteers welcome
- Sponsor
- Hasanuddin University
Acute Heart Failure, Congestive Heart Failure
The Role of intraABDOminal Pressure and Point Of Care UltraSound to Guide Decongestive Therapy in Heart Failure
Systemic venous congestion is the primary therapeutic target of intravenous loop diuretics in patients admitted for acute heart failure (AHF).
- Conditions
- Acute Heart Failure, Congestive Heart Failure, Intraabdominal Hypertension, Cardio-Renal Syndrome
- Trial name
- ABDOPOCUS-HF (NCT07008365)
- Testing
- Furosemide 20 Milligrams
- Where
- 2 sites in Spain
- Volunteers
- 168 people
- Sponsor
- Instituto de Investigación Sanitaria Aragón
Intubation; Difficult or Failed
Comparison of Ultrasound Techniques for Assessment of Endotracheal Tube Placement
This study is a single-center, randomized clinical trial conducted in an emergency department on intubated patients with rapid sequence intubation.
- Trial name
- NCT06656546
- Testing
- Tracheal Ultrasound, Lung Ultrasound, Diaphragm Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
SARS-Cov-2, Covid19
Clinical Evaluation of a Point-of-Care (POC), SARS-CoV-2 (COVID-19) IgG Antibody Test in Fingerstick Whole Blood
Prospective, multi-center, observational, blinded clinical trial to compare a new point of care (POC) SARS-CoV-2 IgG antibody test to a reference SARS-CoV-2 PCR test using fingerstick whole blood.
- Trial name
- NCT04699903
- Testing
- POC SARS-Cov-2 IgG Antibody test
- Where
- 3 sites in United States
- Volunteers
- 201 people
- Sponsor
- Lumos Diagnostics
Psoriatic Arthritis
Validation of Handheld Ultrasound Devices in Rheumatology
The goal of this clinical trial is to test the concurrent validity of the Clarius handheld ultrasound devices versus gold-standard device to detect characteristic features of healthy and rheumatic joints in adults Psoriatic…
- Trial name
- NCT06580886
- Testing
- Ultrasound
- Where
- 3 sites in United States, Canada
- Volunteers
- 30 people
- Sponsor
- Ottawa Hospital Research Institute
Hip Effusion
Hip POCUS for the Diagnosis of Pediatric Hip Effusion.
Limping is a common complaint among children presenting in the Pediatric ED the evaluation of a limp among infants and toddlers is challenging doe to the lack of specific history and the difficulty in locating the pain …
- Trial name
- NCT04720066
- Testing
- Ultrasound test
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Meir Medical Center
Congenital Heart Disease
Evaluation of Coagulation Testing in Patients Undergoing Cardiac Surgery
Neonates, children with single ventricle congenital heart disease, and those undergoing multiple complex cardiac surgeries are at high risk of increased perioperative blood loss, and blood product transfusions.
- Trial name
- NCT02410473
- Testing
- Discarded blood samples, Discarded Urine Sample
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Boston Children's Hospital
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