Clinical trials: Poisoning, Lead
Male Infertility, Testicular Diseases
Effect of Environmental Exposures on the Egg Fertilizing Ability of Human Sperm
Our data indicate that environmental exposure to the heavy metal lead are more widespread than currently appreciated and that such exposures are associated with the production of human male subfertility.
- Conditions
- Male Infertility, Testicular Diseases, Urologic and Male Genital Diseases, Lead Poisoning
- Trial name
- NCT00012480
- Where
- 3 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Poisoning, Lead
Identifying Residential Hazards Using Home Test Kits
The purpose of this project is to help families and communities identify and reduce health risks from lead, pesticides and, ultimately, other environmental hazards.
- Trial name
- NCT00285532
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Lead Poisoning
Effects of Allium Sativum and Moringa Oleifera Extract on Dental Enamel
Primary objective is to observe the effects of lead on dental enamel of rabbit by measuring; Structural and morphological change by SEM, AFM Elemental composition by SEM-EDX Molecular composition and hydroxyapatite crystal…
- Trial name
- NCT05744752
- Testing
- Lead Acetate, Moringa oleifera Extract, Allium sativum Extract
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Arslan Saleem
Alpha-Gal Syndrome
The α-gal Syndrome - Investigating Immune Reactions to Tick Bites
Tick bites can transmit pathogens, but they can also induce a food allergy to mammalian meat. The goal of this clinical trial is to follow immune response and antibody build-up in individuals bitten by a tick.
- Trial name
- ImmunoGal (NCT07177729)
- Where
- 2 sites in Luxembourg
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Luxembourg Institute of Health
Lead Poisoning
Effects of Iron and/or Zinc Supplementation in Mexican School Children Exposed to Lead
Lead is negatively linked to nutritional status, behavior and cognition in children. Despite extensive knowledge of its toxicity and efforts to reduce exposure, lead continues to be a problem in developed and developing…
- Trial name
- NCT02346188
- Testing
- Ferrous fumarate, Zinc oxide
- Where
- United States
- Volunteers
- 602 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Lead Poisoning
RECLEAN Pilot Study
This is an exposure assessment pilot study tailored for families of construction workers living with a child. The investigators will compare home dust metal levels and resident's blood metal levels before and after an educational…
- Trial name
- RECLEAN (NCT04498845)
- Testing
- In-home assessment plan, Family educational session, Worker take home prevention training
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Boston University
Lead Poisoning, Environmental Exposure
A Study to Assess the Efficacy of Public Health Campaigns in Reducing Lead Exposure
This clinical trial aims to evaluate the effectiveness of targeted public health campaigns in reducing lead exposure among adults living in urban communities with known environmental lead hazards.
- Trial name
- NCT07632937
- Testing
- Intensive Public Health Campaign, Standard Information Dissemination
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- International Health Strategies LLC
Lead Poisoning
Bone Lead Levels and College Achievement Scores
This project studies the relationship between lead exposure and academic achievement in college students. Most studies of the neurobehavioral effects of lead have focused on performances at the low end of the distribution.
- Trial name
- NCT00014885
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Iron Deficiency, Lead Poisoning
Iron Fortification Trail Using NaFeEDTA in Iron Deficient Lead-exposed Children
In a cross-sectional study allotted by the ethical committee of the ETH Zurich, we are investigating the extent of anemia, iron deficiency and lead intoxication in young children.
- Trial name
- NCT01573013
- Testing
- iron fortified biscuits
- Where
- Switzerland
- Volunteers
- 457 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Lead Poisoning, Infertility
Lead, Endocrine Disruption and Reproductive Outcomes
This prospective cohort study of 400 lead exposed and 400 non-lead exposed women and their husbands assesses endocrine dysfunction and adverse reproductive outcomes.
- Trial name
- NCT00023101
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Vitamin D Deficiency, Iodine Deficiency
Vitamin D, Iodine, and Lead Levels in Haitian Infants and Children.
Vitamin D deficiency is common worldwide, including in infants and children, and rickets remains a public health concern in many developing countries.
- Conditions
- Vitamin D Deficiency, Iodine Deficiency, Hypothyroidism, Rickets
- Trial name
- Haiti (NCT02301520)
- Where
- 2 sites in Haiti
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Lead Poisoning, Neurotoxicity
Effects of Lead Exposure on Ferroptosis Pathway
The aim of this study was to investigate the effects of chronic lead exposure on iron metabolism and the Nrf2-dependent ferroptosis pathway in lead acid battery factory workers
- Trial name
- NCT05950386
- Testing
- Lead exposure
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Northern Jiangsu People's Hospital
Lead Poisoning
The Combined Effect of 2,3-Dimercaptosuccinic Acid and Multi-Nutrients on Children in Lead Poisoning
Lead poisoning remains a common disease among children despite successful public health efforts that reduced its prevalence.Our study was designed to test the hypothesis that lead-poisoning children (BLLs:100-440µg/L) who were…
- Trial name
- NCT00374894
- Testing
- 2,3-dimercaptosuccinic acid
- Where
- China
- Volunteers
- 500 people
- Sponsor
- China Medical University, China
Poisoning
Effectiveness of Environmental Measures to Eliminate the Risks of Lead Exposure in Infant Lead Poisoning
Infant lead poisoning is the clinical expression of lead poisoning. This environmental disease, still present in France, is the only notifiable non-infectious disease.
- Trial name
- NCT03640143
- Testing
- venous blood lead
- Where
- France
- Volunteers
- 165 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Lead Poisoning
Social Network Based Intervention to Reduce Lead Exposure Among Native American Children
The purpose of this study is to examine whether adding an inter-generational component to an existing social network-based lay health advisor intervention increases its effectiveness in mobilizing a Native American community to…
- Trial name
- NCT00011661
- Testing
- Education on behaviors to reduce lead exposure
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Dietary Habits, Lead Poisoning
Dietry Pattern and Lead Levels in Pregnancy
During pregnancy lead crosses the placenta freely and can have adverse effects on the fetus, with the potential for life-long impact on the child.
- Conditions
- Dietary Habits, Lead Poisoning, Pregnancy Related
- Trial name
- NCT03408275
- Testing
- None - observational
- Volunteers
- 2,167 people, healthy volunteers welcome
- Sponsor
- University of Bristol
Lead Poisoning, Lead Poison Children
Evaluation of the Impact of a Personal and Domestic Hygiene Intervention on Lead Exposure in a Community Close to a Mine Dump
The study evaluates the impact of a personal and domestic hygiene intervention on exposure to lead in a community close to a mine dump.
- Trial name
- NCT05265572
- Testing
- Domestic Hygiene and household hygiene Intervention
- Where
- South Africa
- Volunteers
- 576 people, healthy volunteers welcome
- Sponsor
- University of Johannesburg
Lead Poisoning
Does Lead Burden Alter Neuropsychological Development?
Inner city children are at an increased risk for lead overburden. This in turn affects cognitive functioning. However, the underlying neuropsychological effects of lead overburden and its age-specific effects have not been well…
- Trial name
- NCT00000104
- Testing
- ERP measures of attention and memory
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Center for Research Resources (NCRR)
Lead Poisoning
Early Exposure to Lead and Adult Antisocial Outcomes
Prior research indicates a link between early lead exposure and risk for delinquent behavior. In this study, we follow a large birth cohort from the Cincinnati Lead Study into early adulthood to determine whether this increased…
- Trial name
- NCT00285610
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Ischemic Heart Disease, Coronary Artery Disease
Heavy Metals, Angiogenesis Factors and Osteopontin in Coronary Artery Disease (CAD)
The present study aims is to investigate: 1. whether patients suffering from acute resp. chronic ischemic heart disease show higher levels for cadmium (Cd), lead (Pb) and mercury (Hg) than local and international reference levels…
- Conditions
- Ischemic Heart Disease, Coronary Artery Disease, Heavy Metal Toxicity
- Trial name
- NCT02159235
- Where
- Austria
- Volunteers
- 200 people
- Sponsor
- Medical University of Vienna