Clinical trials: Poisoning
Pain
Pilot Study of the Effect of Transcutaneous Stimulation of the Vagus Nerve on Pain Perception and Parameters of the Autonomic Nervous System
The increased incidence of pain syndromes requires the investigation of pathophysiological coherences as well as searching for new therapies.
- Trial name
- NCT01174498
- Testing
- Cerbomed t-VNS® transcutaneous stimulation
- Where
- Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- cerbomed GmbH
Anesthesia, Block
Evaluating the Effectiveness of Bilateral ESPB in Addition to Standard Analgesia at Reducing Opioid Consumption
Study the benefits of a Erector Spinae nerve block for pain control and decrease narcotics usage after mammoplasty in an ambulatory setting
- Trial name
- NCT03954249
- Testing
- Erecto Spinae nerve block, Multimodal Analgesia
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Hypercapnia, Exercise
Hypercapnia: Cognitive Effects and Monitoring
The investigators will simulate the conditions of a working, helmeted diver by using exercising, "head out" immersed subjects to test the following hypotheses: 1.
- Conditions
- Hypercapnia, Exercise, Nitrogen Narcosis, Diving
- Trial name
- NCT01782625
- Testing
- NO exercise at depth, exercise at depth
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Duke University
Dental Occlusion
Patient Perception and Oral Function of Implant Restorations
The overall aim is to evaluate the patient-reported outcome and efficiency of replacing posterior teeth with implant-supported crowns compared to RDPs and no treatment.
- Trial name
- REPLACE (NCT06463405)
- Testing
- Splinted
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Tuberculosis, Drug-Induced Liver Injury
A Pharamcogenomic Study for Isoniazid According to NAT2 Polymorphism Status
A clinical trial to investigate the appropriate dose of isoniazid according to NAT2 polymorphism status in Korean subjects
- Conditions
- Tuberculosis, Drug-Induced Liver Injury, Adverse Drug Event
- Trial name
- NCT03665402
- Testing
- Isoniazid
- Where
- South Korea
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Occlusion
Characterization of the Temporo-masseteric Nerve Block (TMNB) in Healthy Subjects
The proposed pilot study is aimed at preliminary characterization of the TMNB injection in 20 healthy volunteers. Assessment of bite-force distribution and surface electromyographic activity of the temporalis and the masseter…
- Trial name
- NCT05507164
- Testing
- Temporomasseteric Nerve Block
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Overjet, Dental
Sleep, Upper Airway and Dental Occlusion in Children With Large Overjet
This project examines sleep (e.g. prevalence of obstructive sleep apnea(OSA)), dimension of upper airway, jaw function, well-being and quality of life in children with large overjet compared to a control group.
- Trial name
- NCT04964830
- Testing
- Orthodontic treatment with functional appliance (MAD)
- Where
- Denmark
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Dental Occlusion, Occlusal Wear of Teeth
Evaluation of Occlusal Adjustment Material Removal on Monolithic Zirconia Blocks: An In Vitro Study
This study aims to improve understanding of the amount of tooth-replacement material removed during a single grinding "stroke" performed in the adjustment of a zirconia crown.
- Conditions
- Dental Occlusion, Occlusal Wear of Teeth, Fixed Dental Prosthesis
- Trial name
- NCT07280130
- Testing
- perform material removal on monolithic zirconia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Tick Bites, Tick Resistance
Acquired Tick Resistance in Naturally Exposed Participants
Tick-borne diseases are increasing worldwide, and there are currently few effective ways to prevent them. One promising new strategy is to develop a vaccine that targets the tick itself ("anti-tick vaccine") to block the…
- Trial name
- TICK REACT (NCT07479537)
- Testing
- Tick challenge
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Nitrous Oxide Poisoning
Effects of Low Concentrations of Nitrous Oxide
The aim of the study is to test the effects of low concentrations of nitrous oxide on cognitive functions and reaction time in human.
- Trial name
- NCT04050267
- Testing
- Nitrous Oxide
- Where
- Czechia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Czech Technical University in Prague
Dental Occlusion, Occlusal Analysis
Trueness of Digital Occlusal Analysis
The aims of this observational study are to evaluate the trueness of two different digital occlusal analyzers; handheld occlusal analyzer versus intraoral scanner in comparison to conventional methods in identifying true occlusal…
- Trial name
- NCT06672627
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Snakebite, Epidemiology
Mapping Snakebite Risk in Kenya and Eswatini
The goal of this observational study is to learn about how snakebite risk varies in different environments in Kenya and understand how this information can be used to support decision makers.
- Trial name
- NCT06124872
- Testing
- Survey questionnaire, Key informant interview
- Where
- Kenya
- Volunteers
- 70,000 people, healthy volunteers welcome
- Sponsor
- Liverpool School of Tropical Medicine
Alpha-Gal Syndrome
The α-gal Syndrome - Investigating Immune Reactions to Tick Bites
Tick bites can transmit pathogens, but they can also induce a food allergy to mammalian meat. The goal of this clinical trial is to follow immune response and antibody build-up in individuals bitten by a tick.
- Trial name
- ImmunoGal (NCT07177729)
- Where
- 2 sites in Luxembourg
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Luxembourg Institute of Health
Poisoning
Health Professions Students and Faculty Perceptions of Poisoning Severity
Inaccurate perceptions of the severity of an exposure may result in unnecessary visits to the Emergency Department or Health Care Facility which can result in crowding of Emergency Departments, unnecessary utilization of valuable…
- Trial name
- NCT02553070
- Testing
- Survey
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Florida
Heavy Metal Toxicity
Investigation of Wet Cupping Therapy on Heavy Metal Levels of Steel Industry Workers
This interventional study investigates the efficacy of Wet cupping therapy on heavy metal levels.The levels of the selected heavy metals will be measured in the blood samples obtained from the participants before and after the…
- Trial name
- NCT03693079
- Testing
- Wet cupping therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Pulmonary Hypertension, Metal Poison
Study Roles of Heavy Metals and Essential Metal Dyshomeostasis in Pulmonary Arterial Hypertension Patients
Investigators plan to recruit 50 PAH patients from UofL PAH Clinic, with various degrees of severity (25 intermediate risk patients and 20 high risk patients) and 10 age and gender matched controls.
- Trial name
- NCT04756076
- Testing
- Metal level measurements
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Jiapeng Huang
Iron Deficiency, Lead Poisoning
Iron Fortification Trail Using NaFeEDTA in Iron Deficient Lead-exposed Children
In a cross-sectional study allotted by the ethical committee of the ETH Zurich, we are investigating the extent of anemia, iron deficiency and lead intoxication in young children.
- Trial name
- NCT01573013
- Testing
- iron fortified biscuits
- Where
- Switzerland
- Volunteers
- 457 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Rheumatoid Arthritis, Osteoarthritis
Low Dose Dexamethasone in Supraclavicular Blocks
Brachial plexus nerve blocks provide superior analgesia over opioids while avoiding unwanted side effects. Single shot blocks with local anesthetic alone usually do not last the duration of the acute post-surgical pain period.
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Nerve Entrapment, Ligament Injury
- Trial name
- NCT02666443
- Testing
- Control intervention (no dexamethasone), Peri-neural Dexamethasone 1 mg, Intravenous Dexamethasone 1 mg
- Where
- Canada
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Botulism
Phase 3, Randomized, Safety, Lot Consistency and Clinical Benefit Study of Recombinant Botulinum Vaccine A/B
This Phase 3 clinical trial is a double blind, placebo-controlled, randomized, multicenter investigation of rBV A/B in male and female healthy adults 18 to 55 years of age.
- Trial name
- rBV A/B (NCT01940315)
- Testing
- rBV A/B
- Volunteers
- healthy volunteers welcome
- Sponsor
- DynPort Vaccine Company LLC, A GDIT Company
Crossbite, Openbite
Implications of Pacifier Use in Israeli Children
The purpose of this study is to examine pacifier sucking habits among children, and to assess implications of the oral habit - for example malocclusions and drooling.
- Conditions
- Crossbite, Openbite, Drooling
- Trial name
- NCT01249885
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization