Clinical trials: Poisoning
Ricin Poisoning
Booster Dose (50 µg) of Recombinant Ricin Toxin Vaccine (RVEc™) in Previously Vaccinated Healthy Adults
The purpose of this study is to evaluate the safety and immunogenicity of a single 50-μg booster dose of RVEc. Subjects will be recruited from the cohort that received three 50-μg doses of RVEc in a Phase 1 trial (NCT01317667).
- Trial name
- RVEc (NCT01846104)
- Testing
- 50-μg booster dose RVEc
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- U.S. Army Medical Research and Development Command
Volunteers Repeated Drug Poisoning, Alcoholic
Repeated Voluntary Drug Intoxication (IMVr): Characterization of a New Addictive Behavior by Clinical Phenotyping and Functional Imaging
France is one of the European countries with the highest rate of death by suicide, more than 10 400 deaths each year, about 16 people out of 100 000.
- Conditions
- Volunteers Repeated Drug Poisoning, Alcoholic, Volunteers
- Trial name
- Phenot IMVr (NCT02889042)
- Testing
- MRI and biological assessment
- Where
- France
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Carbon Monoxide Poisoning
Is Transcutaneous Carbon Monoxide Saturation of E-cigarette Users Comparable to That of Smokers?
Suspicions of carbon monoxide poisoning that lead to the treatment of victims are numerous. Measurement of transcutaneous carbon monoxide saturation (SpCO) is a useful diagnostic and triage tool for victims and the toxic…
- Trial name
- COVAP (NCT03669848)
- Testing
- Pulse CO-oximetry
- Where
- France
- Volunteers
- 1,116 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Drug Overdose, Overdose of Beta-adrenergic Blocking Drug
Glucagon's Cardiovascular Effects With and Without Beta-blocker-induced Cardioinhibition
This trial investigates effects of a glucagon bolus injection on heart rate, blood pressure and cardiac output during beta-blocker-induced cardiodepression.
- Trial name
- GLUCAGON (NCT03533179)
- Testing
- Glucagon, Esmolol, Physiologic saline - glucagon dummy
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Nitrous Oxide Poisoning
Effects of Low Concentrations of Nitrous Oxide
The aim of the study is to test the effects of low concentrations of nitrous oxide on cognitive functions and reaction time in human.
- Trial name
- NCT04050267
- Testing
- Nitrous Oxide
- Where
- Czechia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Czech Technical University in Prague
Pesticide Poisoning
A Community Trial to Determine Whether 'Safe Storage' Reduces Pesticide Self-poisoning in Rural Asia
A major global public health priority is to identify effective methods for preventing deaths from pesticide self-poisoning. The aim of this work is to determine whether the provision of lockable storage containers to poor…
- Trial name
- NCT01146496
- Testing
- Ultraviolet light-resistant plastic in-ground pesticide storage container
- Where
- Sri Lanka
- Volunteers
- 223,861 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Malnutrition, Child, Arsenic Poisoning Chronic
Effect of Chronic Arsenic Exposure on Malnutrition of Under Five Children
Early life malnutrition is associated with later life health problems, Particularly Stunting, which is a height-for-age Z score less than -2 standard deviation of World Health Organization median.Underweight is weight-for-age Z…
- Trial name
- NCT03893721
- Testing
- arsenic exposure
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Tutin Poisoning
A Study of How Tutin and Hyenanchin, Two Toxins Found in Honey, Are Absorbed and Processed by the Body
Honey available in New Zeland can contain the toxins tutin and hyenanchin. Tutin is produced by several plants native to New Zealand. Bees collect honeydew contaminated with tutin and hyenanchin for honey production.
- Trial name
- NCT03826537
- Testing
- Honey substance
- Where
- New Zealand
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Christchurch Clinical Studies Trust Ltd
Dental Fluorosis
Presence of Enamel Fluorosis in Libyan Children
Fluorosis is caused by hypomineralization in the enamel due to increased fluoride ingestion during early childhood (Cawson.1, Wong et al. 2, and Sudhir 3).
- Trial name
- NCT03746990
- Volunteers
- 1,935 people, healthy volunteers welcome
- Sponsor
- Ajman University
Heavy Metal Toxicity
Investigation of Wet Cupping Therapy on Heavy Metal Levels of Steel Industry Workers
This interventional study investigates the efficacy of Wet cupping therapy on heavy metal levels.The levels of the selected heavy metals will be measured in the blood samples obtained from the participants before and after the…
- Trial name
- NCT03693079
- Testing
- Wet cupping therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Pesticide Poisoning
Evaluation of Pesticide Exposure in the General Population
An association has been suggested with several diseases including cancer and IARC has classified several pesticides as carcinogenic, probably carcinogenic.
- Trial name
- SIGEXPOSOME (NCT02986763)
- Testing
- Questionnaire, blood, urine, hair and dust samplings
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Centre Leon Berard
Dietary Habits, Lead Poisoning
Dietry Pattern and Lead Levels in Pregnancy
During pregnancy lead crosses the placenta freely and can have adverse effects on the fetus, with the potential for life-long impact on the child.
- Conditions
- Dietary Habits, Lead Poisoning, Pregnancy Related
- Trial name
- NCT03408275
- Testing
- None - observational
- Volunteers
- 2,167 people, healthy volunteers welcome
- Sponsor
- University of Bristol
Arsenic Poisoning Chronic
Selenium and Arsenic Pharmacodynamics
This clinical trial should prove that selenium can treat arsenic exposure in humans by promoting excretion. The new trial differs from previous trials in that participants will be maintained in a local clinic and provided with…
- Trial name
- SEASP (NCT02377635)
- Testing
- Anhydrous selenite, Sodium chloride
- Where
- Bangladesh
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Heavy Metal Toxicity
Prolonged Gadolinium Retention After MRI Imaging
The researchers propose to investigate the prevalence of gadolinium in the urine of patients with a prior gadolinium-enhanced MRI before and after a edetate calcium disodium challenge.
- Trial name
- NCT02421029
- Testing
- edetate calcium disodium
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mt. Sinai Medical Center, Miami
Lead Poisoning
Plan for Testing Fingerstick Bloods on Magellan Systems
This study is to supplement our internal data that demonstrates the continued performance of capillary blood samples on Magellan's lead testing systems: LeadCare II, LeadCare Ultra (which have been cleared previously by FDA), and…
- Trial name
- NCT03256383
- Testing
- Lead testing
- Where
- 3 sites in United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Magellan Diagnostics
Acetaminophen Metabolism, Acetaminophen Poisoning
Effect on Acetaminophen Metabolism by Liquid Formulations
The purpose of this study is to determine whether excipients in the liquid formulation of acetaminophen prevent the formation of the toxic metabolites of acetaminophen.
- Conditions
- Acetaminophen Metabolism, Acetaminophen Poisoning, Drug Metabolism by Excipients
- Trial name
- NCT01246713
- Testing
- Acetaminophen liquid formulation, Acetaminophen solid formulation
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Arsenic Poisoning
High-selenium Lentils Versus Arsenic Toxicity
About 45 million people in Bangladesh are chronically exposed to unacceptable levels of arsenic in their drinking water. Chronic arsenic poisoning leads to cancers, and vascular diseases.
- Trial name
- NCT02429921
- Testing
- high-selenium lentils, Low-Se lentils
- Where
- Bangladesh
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Caries, Dental, Gingivitis
Dental Health Epidemiology Among Israel Defense Forces (IDF) Recruits
An epidemiological survey for prevalence description of dental morbidity (caries, gingivitis, dental trauma and fluorosis) among Israel Defense Forces (IDF) general recruits.
- Conditions
- Caries, Dental, Gingivitis, Fluorosis, Dental Trauma
- Trial name
- NCT02958891
- Testing
- Data collection
- Where
- Israel
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Medical Corps, Israel Defense Force
Healthy
Effect of Activated Charcoal on Rivaroxaban Pharmacokinetics in Healthy Subjects
Rivaroxaban is a direct oral anticoagulant that target specifically activated factor X. Bleeding events related to rivaroxaban are the consequence of physiopathologic, pharmacokinetic issues or poisoning.
- Trial name
- RICHAR (NCT02657512)
- Testing
- rivaroxaban, rivaroxaban and activated charcoal
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Dietary Carcinogenesis
Phase 2 Reduction of Dietary Mycotoxin Exposure by ACCS100"
The primary purpose of the study is to evaluate the effectiveness of a naturally occurring clay substance (ACCS100) in reducing harmful effects of aflatoxin exposure (a carcinogen) and fumonisin (a cancer promoter).
- Trial name
- RDMEACCS100 (NCT01677195)
- Testing
- ACCS100
- Where
- United States
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- Texas Enterosorbents Incorporated