Clinical trials: Pollen; Allergy, Asthma
Allergic Rhinoconjunctivitis
Subcutaneous Immunotherapy in Patients Sensitized to Phleum Pratense
Based on EMA (European Medicines Agency) new guidelines on the clinical development of products for immunotherapy for the treatment of allergic disease the aim of this study was to assess safety and tolerability of three…
- Trial name
- NCT01489033
- Testing
- Subcutaneous immunotherapy with Phleum pratense pollen extract
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Roxall Medicina España S.A
Pollen; Allergy, Asthma
Does Medicinal Mushroom Agaricus Blazei Protect Against Allergy and Asthma?
Asthma and allergy is increasing in Norway and Western countries. Treatment is still mostly symptomatic. Extracts of the immunomodulatory and edible mushroom Agaricus blazei, such as Andosan™, have been shown to protect against…
- Trial name
- NCT03198455
- Testing
- Agaricus blazei Murill-based mushroom extract, Andosan™
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Rhinitis, Allergic, Conjunctivitis, Allergic
Evaluation of Subcutaneous Immunotherapy Towards Pollen in Children
The objective is to prospectively explore associations between immunological parameters in blood and clinical effect of subcutaneous immunotherapy (SCIT) in children with severe allergy towards pollen.
- Conditions
- Rhinitis, Allergic, Conjunctivitis, Allergic, Asthma
- Trial name
- NCT03375775
- Testing
- Subcutaneous immunotherapy with ALK Alutard birch or ALK Alutard timothy, No immunotherapy, symptomatic treatment
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Rhinitis, Conjunctivitis
Study on Pharmacodynamic Parameter and Tolerability With Subcutaneous Immunotherapy in Grass Pollen Allergic Patients
The aim of this study is to test the pharmacodynamic equivalence with respect to IgE-blocking factor and to compare the tolerability of two different updosing schedules with ALK-Flex SQ
- Conditions
- Rhinitis, Conjunctivitis, Asthma
- Trial name
- NCT00857779
- Testing
- subcutaneous immunotherapy
- Where
- Germany
- Volunteers
- 473 people
- Sponsor
- ALK-Abelló A/S
Asthma
Safety and Efficacy of Ultra-Rush Sublingual Immunotherapy in Children With Asthma Allergic to Grass Pollen
The aim of the study is to assess the safety and efficacy of sublingual immunotherapy applied preseasonal and seasonal in ultra-rush scheme in children with bronchial asthma allergic to grass pollen.
- Trial name
- NCT00518518
- Testing
- Staloral 300
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Lodz
Rhinitis, Allergic, Seasonal, Asthma
Study of the Effectiveness and Safety of Desloratadine (Aerius) Syrup in Children With Hayfever With or Without Asthma (P03472)
The purpose of this study was to test the effectiveness and safety of desloratadine (Aerius) syrup in children with hayfever with or without asthma. Patients took desloratadine syrup once a day for 28 days.
- Trial name
- NCT00805324
- Testing
- Desloratadine
- Volunteers
- 54 people
- Sponsor
- Organon and Co
Rhinitis, Allergic, Seasonal
Grass Pollen Immunotherapy Using a Cluster Regime for Seasonal Rhinitis and Asthma
The purpose of this study was to assess the effects of grass pollen immunotherapy on symptoms, bronchial hyperresponsiveness and quality of life in seasonal rhinitis and asthma.
- Trial name
- NCT00135642
- Testing
- Subcutaneous Alutard SQ grass pollen (Phleum pratense), Venepuncture: 20 ml blood sample taken on 2 separate visits
- Where
- United Kingdom
- Volunteers
- 44 people
- Sponsor
- Imperial College London
Asthma, Rhinitis
Oral Bacteria and Allergic Disease in Children
This study will see if bacteria differ between children who have allergies or asthma and children who do not have allergies or asthma. Previous research suggests that some bacteria may protect against allergies and asthma.
- Conditions
- Asthma, Rhinitis, Eczema, Respiratory Sounds
- Trial name
- NCT00438646
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Type I-Allergy
Dose-Response-Study With a Recombinant Cocktail of Phleum (rPhleum) Allergens
Dose-response trial with a cocktail of recombinant major allergens of Timothy Grass Pollen (Phleum pratense)
- Trial name
- NCT00666341
- Testing
- rPhleum
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Allergopharma GmbH & Co. KG
Allergic Asthma, Thunderstorm Asthma
Creating A Risk Assessment Tool for Thunderstorm Asthma: the CARISTA Study
Thunderstorm asthma is a recurring public health emergency in South-Eastern Australia which occurs in springtime. The major identified risk factors for thunderstorm asthma is hay fever and allergy to ryegrass pollen.
- Conditions
- Allergic Asthma, Thunderstorm Asthma, Seasonal Allergic Rhinitis, Grass Pollen Allergy
- Trial name
- CARISTA (NCT07055542)
- Testing
- Observational
- Where
- 6 sites in Australia
- Volunteers
- 530 people, healthy volunteers welcome
- Sponsor
- University of Melbourne
Allergy
Biological Standardization of Allergen Extracts of Pollens of Betula Pendula, Phleum Pratense and Mite Extract of Dermatophagoides Pteronyssinus
Allergen extracts are complex mixtures of proteins and contain varying amounts of allergenic and non-allergenic components. Many factors such as the biovariability, differences in extraction process and subsequent handling of…
- Trial name
- NCT01147159
- Testing
- Extracts of allergens
- Where
- Switzerland
- Volunteers
- 68 people
- Sponsor
- Roxall Medicina España S.A
COVID-19, Coronavirus Infections
Audio Data Collection for Identification and Classification of Coughing
An open access study that will define and collect digital measures of coughing in multiple populations and public spaces using various means of audio data collection.
- Conditions
- COVID-19, Coronavirus Infections, Hay Fever, Asthma
- Trial name
- NCT04326309
- Where
- United States
- Volunteers
- 336 people, healthy volunteers welcome
- Sponsor
- HealthMode Inc.
Rhinitis, Asthma
The Safety and Efficacy of Intralymphatic Immunotherapy in Pollen Allergic Adolescents and Young Adults With Asthma
The study evaluates the safety and efficacy of intralymphatic allergen-specific immunotherapy given to adolescents and young adults who are allergic to grass or birch pollen and have mild or moderate asthma.
- Conditions
- Rhinitis, Asthma, Allergy
- Trial name
- NCT03394508
- Testing
- ALK Alutard birch or 5-grasses, ALK diluent 0,3% human albumin
- Volunteers
- 30 people
- Sponsor
- Karolinska Institutet
Asthma, Seasonal Allergic Rhinitis
Adolescent and Adult Subjects With Asthma and Seasonal Allergic Rhinitis Receiving Advair Diskus or Placebo
The four respiratory drugs being researched in this study have been approved by the US Food and Drug Administration (FDA) and are currently available by prescription at your drug store.
- Trial name
- NCT00385463
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Creighton University
Dermatitis, Atopic
Prevention of Asthma With Levocetirizine 18 Month Treatment in Infants (12 - 24 Months) Suffering From Eczema (Atopic Dermatitis) and Sensitized to Grass Pollen and/or House Dust Mite (HDM)
The Early Prevention of Asthma in Atopic Children (EPAAC™). 24 months study to evaluate the efficacy and safety of levocetirizine (LCTZ) in preventing the onset of asthma in 12 to 24 months old children.
- Trial name
- NCT00152464
- Testing
- Levocetirizine
- Volunteers
- 514 people
- Sponsor
- UCB Pharma SA
Seasonal Affective Rhinitis, Asthma
Seasonal Allergic Rhinitis Study
The study aims to examine the effect of probiotics on the clinical symptoms of allergic rhinitis and to elucidate some of the immunological mechanisms involved.
- Conditions
- Seasonal Affective Rhinitis, Asthma, Grass Allergy
- Trial name
- SAR (NCT01123252)
- Testing
- Lactobacillus casei Shirota (LcS)
- Where
- 4 sites in United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of East Anglia
Allergy
Efficacy and Safety of Grazax in Children
The purpose of this study is to investigate if immunotherapy with Grazax is safe and reduces the hayfever symptoms and the use of symptom relieving medications in children during the grass pollen season
- Trial name
- NCT00408616
- Testing
- Grazax-R
- Where
- Germany
- Volunteers
- 253 people
- Sponsor
- ALK-Abelló A/S
Rhinoconjunctivitis, Rhinitis
Efficacy and Safety of Grass Sublingual Tablet in Children and Adolescents (P05239 AM3)(COMPLETED)
The purpose of the study is to investigate the efficacy and safety of a grass sublingual tablet in children and adolescents with a history of grass-pollen induced rhinoconjunctivitis with or without asthma.
- Conditions
- Rhinoconjunctivitis, Rhinitis, Conjunctivitis, Allergy
- Trial name
- NCT00550550
- Testing
- SCH 697243, Loratadine Syrup 1 mg/mL Rescue Treatment, Loratadine 10 mg Rescue Treatment
- Volunteers
- 345 people
- Sponsor
- ALK-Abelló A/S
Allergic Rhinoconjunctivitis, Allergic Asthma
Validation of Combined Symptom Medication Score (cSMS) in Allergic Patients
The CSMS was defined by the European Academy of Allergy and Immunology Taskforce as a standardised tool to assess clinical effects of allergen-specific immunotherapy (AIT).
- Trial name
- NCT03850626
- Testing
- Immunotherapy
- Where
- Germany
- Volunteers
- 168 people
- Sponsor
- Leti Pharma GmbH
Allergic Rhinitis Due to Grass Pollens
Molecular and Cellular Mechanism in the Course of Immunotherapy With a Phleum Pratense Oral Lyophilisate
This trial is an exploratory randomised, parallel-group, double-blind, placebo- controlled, national, single-centre trial. The trial will be initiated before 2013 grass pollen season and subjects will be randomised in September…
- Trial name
- NCT01854736
- Testing
- Grazax
- Where
- 2 sites in Spain
- Volunteers
- 51 people
- Sponsor
- ALK-Abelló A/S