Clinical trials: Pollinosis
Rhinitis, Allergic
A Study to Compare the Efficacy of Levocetirizine to Placebo in Reducing Symptoms of Seasonal Allergic Rhinitis (SAR) in Sensitive Subjects Exposed to Ragweed Pollen
The purpose of the study is to assess the efficacy comparability of cetirizine and levocetirizine, by comparing the effects of single intake of the two drugs to placebo in reducing symptoms of seasonal allergic rhinitis (SAR) in…
- Conditions
- Rhinitis, Allergic, Seasonal
- Trial name
- NCT00291642
- Testing
- Levocetirizine drops, Levocetirizine tablets
- Where
- Canada
- Volunteers
- 551 people
- Sponsor
- UCB Pharma
Seasonal Allergic Rhinitis (SAR)
Study on the Treatment of Adolescent Patients With Seasonal Allergic Rhinitis
This is a multicenter, randomized, double-blind, placebo-controlled phase III clinical study aimed at evaluating the efficacy and safety of stapokibart in adolescent patients with seasonal allergic rhinitis, and observing the…
- Trial name
- NCT07678931
- Testing
- Stapokibart
- Where
- 27 sites in China
- Volunteers
- 136 people
- Sponsor
- Chengdu Kangnuoxing Biopharma,Inc.
Seasonal Allergic Rhinitis
Phase II Study of JT002 in the Treatment of Seasonal Allergic Rhinitis in Adults
The study included three phases: the treatment introduction period (4-7 days before randomization), the treatment period (14 days after randomization) and the follow-up period (7 days after the last dose).
- Trial name
- NCT06861101
- Testing
- JT002 Nasal spray
- Where
- 44 sites in China
- Volunteers
- 370 people
- Sponsor
- Shanghai JunTop Biosciences Co., LTD
Seasonal Allergic Rhinitis
Effect of a Nasal Bolus Allergen Challenge on Inflammatory Markers
The current study will investigate nasal inflammatory markers obtained by filter paper collection techniques, in subjects with allergic rhinitis, determining the most appropriate time points and handling conditions, prior to…
- Trial name
- NCT00483353
- Testing
- Intra-nasal allergen challenge with Phleum pratense., Collection of nasal effluent using filter paper., Measurement of nasal congestion using acoustic rhinometry.
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- Pfizer
Hayfever, Allergy Pollen
Breathe-Easy: Hayfever Care for Patients With Seasonal Allergic Rhinitis
This waitlist-controlled trial aims to evaluate the therapeutic effectiveness of Hayfever Care by assessing disease-specific symptoms over a 4-week period.
- Conditions
- Hayfever, Allergy Pollen, Allergic Rhinitis
- Trial name
- NCT06765239
- Testing
- Hayfever Care, Wait-list Control
- Where
- India
- Volunteers
- 63 people
- Sponsor
- Innowage Limited
Allergic Rhinitis/Rhinoconjunctivitis +- Intermittent Asthma, Sensitization Against Phleum Pratense Pollen
Dose Finding Study Depigoid Phleum: 4 Doses in Patients With Allergic Rhinitis/Rhinoconjunctivitis +-Asthma
Specific immunotherapy for IgE mediated sensitization to grass pollen 4 concentrations of a modified pollen extract of Phleum pratense are applied to find out the optimum dose.
- Conditions
- Allergic Rhinitis/Rhinoconjunctivitis +- Intermittent Asthma, Sensitization Against Phleum Pratense Pollen, Dose-Finding Study
- Trial name
- NCT01634958
- Testing
- Depigoid Phleum
- Where
- 2 sites in Germany
- Volunteers
- 308 people
- Sponsor
- Leti Pharma GmbH
Allergic Rhinoconjunctivitis, Perennial Allergic Rhinitis
Efficacy and Safety Evaluation for the Treatment of Asthma and Allergic Rhinitis/Rhinoconjunctivitis
Prospective, randomized, placebo-controlled, multicenter of 3 active treatment groups, compared to 1 placebo group, for the determination of the efficacy and safety of subcutaneous immunotherapy in patients with mild to moderate…
- Conditions
- Allergic Rhinoconjunctivitis, Perennial Allergic Rhinitis, House Dust Mite Allergy, Pollen Allergy
- Trial name
- NCT04874714
- Testing
- MM09-MG01(30.000-30.000), MG01(30.000), MM09(30.000)
- Where
- 13 sites in Spain
- Volunteers
- 18 people
- Sponsor
- Inmunotek S.L.
Allergic Rhinitis, Seasonal Allergic Rhinitis
Post Marketing Surveillance for Contac Bien Z in Japan
This is a post-marketing surveillance study on a marketed cetrizine hydrochloride formulation.
- Trial name
- NCT02020902
- Testing
- Cetrizine hydrochloride
- Where
- Japan
- Volunteers
- 1,552 people
- Sponsor
- GlaxoSmithKline
Seasonal Allergic Rhinitis
Subcutaneous Immunotherapy Treatment for Patients With Hypersensitivity to Grass Pollen
The objective of this trial is to assess the clinical efficacy of the modified extract (depigmented and polymerised with glutaraldehyde)of the subcutaneous injection of Phleum pratense pollen in the treatment of patients affected…
- Trial name
- NCT00916422
- Testing
- Allergen extract (Phleum pratense)
- Where
- 23 sites in Hungary, Spain
- Volunteers
- 153 people
- Sponsor
- Laboratorios Leti, S.L.
Hypersensitivity
Safety and Efficacy of an Allergen Vaccine in Grass-Pollen Allergy
The purpose of this study is to evaluate whether the use of a specific immunomodulatory principle (QbG10) together with conventional grass pollen allergen leads to a more rapid and more pronounced decrease of sensitivity against…
- Trial name
- NCT00293904
- Testing
- CYT005-AllQbG10
- Where
- Switzerland
- Volunteers
- 36 people
- Sponsor
- Cytos Biotechnology AG
Allergic Rhinitis
Phase 2 Study in Adults Sensitized to Short Ragweed
The purpose of this study is to identify an effective dose of allergen-specific immunotherapy for short ragweed (Ambrosia artemisiifolia) administered by an oral/sublingual route.
- Trial name
- NCT00670384
- Testing
- Standardized Allergenic Extract, Short Ragweed (Ambrosia artemisiifolia)
- Sponsor
- Antigen Laboratories, Inc.
Birch Pollen Allergy
Study of DM-101PX in Adults With Birch Pollen Allergy
Randomized, double-blind placebo-controlled phase 2 trial with the aim to investigate safety and efficacy of DM-101-PX in reducing allergic symptoms provoked by nasal allergen challenge in birch pollen allergic adults.
- Trial name
- BASIT (NCT07254871)
- Testing
- DM-101PX
- Where
- Canada
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Desentum Oy
Seasonal Allergic Rhinitis
Montelukast in Seasonal Allergic Rhinitis - Fall 1999 Study (0476A-117)
This study will evaluate the ability of oral montelukast/loratadine to improve the signs and symptoms of seasonal allergic rhinitis compared with loratadine alone, montelukast alone and placebo.
- Trial name
- NCT00963599
- Testing
- Comparator: montelukast/loratadine, Comparator: montelukast, Comparator: loratadine
- Volunteers
- 907 people
- Sponsor
- Organon and Co
Rhinitis, Allergic, Seasonal
Compare the Efficacy of Levocetirizine and Montelukast to Placebo in Reducing Seasonal Allergic Rhinitis (SAR) Symptoms in Ragweed Sensitive Subjects
To compare the clinical efficacy of levocetirizine 5 mg and montelukast 10 mg on symptoms of seasonal allergic rhinitis occurring in subjects exposed to ragweed pollen in an environmental exposure unit.
- Trial name
- NCT00295022
- Testing
- Montelukast, Levocetirizine
- Where
- Canada
- Volunteers
- 418 people
- Sponsor
- UCB S.A. - Pharma Sector
Allergic Rhinitis, Perennial Allergic Rhinitis
Clinical Trial to Evaluate the Safety and Efficacy of AGR Tablet as a Treatment of Perennial Allergic Rhinitis in Korean
The purpose of this study is to evaluate treatment of perennial allergic rhinitis in Korean patients with AGR tablet.
- Conditions
- Allergic Rhinitis, Perennial Allergic Rhinitis, Non-seasonal Allergic Rhinitis
- Trial name
- NCT01982916
- Testing
- AGR tablet, Active Comparator
- Where
- 9 sites in South Korea
- Volunteers
- 324 people
- Sponsor
- Ahn-Gook Pharmaceuticals Co.,Ltd
Allergy
A Trial of Grazax in Subjects With Hayfever
The trial is performed to evaluate the efficacy and safety of specific immunotherapy with Grazax for treatment of grass pollen induced allergy.
- Trial name
- NCT00421655
- Testing
- Grazax
- Where
- United States
- Volunteers
- 329 people
- Sponsor
- ALK-Abelló A/S
Seasonal Allergic Rhinitis
Phase II/III Seamless Clinical Study of MG-K10 Humanized Monoclonal Antibody Injection in Treatment of Seasonal Allergic Rhinitis
A multicenter, randomized, double-blind, placebo-controlled Phase II/III seamless clinical study evaluating the efficacy, safety, pharmacokinetic (PK) profile, pharmacodynamic (PD) profile, and immunogenicity of MG-K10 humanized…
- Trial name
- NCT06846385
- Testing
- MG-K10 Humanized Monoclonal Antibody Injection
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Shanghai Mabgeek Biotech.Co.Ltd
Rhinitis, Allergic, Perennial
Comparator Study Evaluating Patient Preference Of FFNS vs. FPNS
The purpose of this replicate study to FFU105927 is to provide data on subject preference of FFNS as compared with FPNS.
- Trial name
- NCT00539006
- Testing
- FPNS, FFNS
- Where
- 24 sites in United States
- Volunteers
- 377 people
- Sponsor
- GlaxoSmithKline
Seasonal Allergic Rhinitis
Mometasone Furoate on Sleep Disturbances in Subjects With Seasonal Allergic Rhinitis (Study P04608) (COMPLETED)
This study will hope to show that by relieving the participant's nasal symptoms of seasonal allergies using mometasone furoate nasal spray, the participant will obtain a better quality of night-time sleep, which in turn, causes…
- Trial name
- NCT00358527
- Testing
- Mometasone Furoate Nasal Spray (MFNS)
- Volunteers
- 401 people
- Sponsor
- Organon and Co
Rhinitis, Allergic, Seasonal
Study In Adults And Adolescents With Seasonal Allergic Rhinitis.
Compare the efficacy and safety of an investigational nasal spray compared with placebo nasal spray in the treatment of seasonal allergic rhinitis.
- Trial name
- NCT00225823
- Testing
- GW685698X
- Where
- 24 sites in Estonia, Latvia and 4 more
- Volunteers
- 288 people
- Sponsor
- GlaxoSmithKline