Clinical trials: Polycystic Ovary Syndrome
Polycystic Ovary Syndrome
Coenzyme Q10 and Clomiphene Citrate (CC) for Ovulation Induction in Polycystic Ovary Syndrome
Objective of the study was to evaluate the effect of combination of oral Coenzyme Q10 (CoQ10), with clomiphene citrate (CC) for ovulation induction in CC-resistant polycystic ovary syndrome (PCOS).In a prospective controlled…
- Trial name
- NCT01910766
- Testing
- Coenzyme Q10, clomiphene citrate
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Mansoura University
Polycystic Ovary Syndrome
Polycystic Ovary Syndrome (PCOS): Effect Of Letrozole and Berberine
Polycystic ovary syndrome (PCOS) is a heterogeneous disorder affecting almost4%-7% of the female population of reproductive age.
- Trial name
- NCT01116167
- Testing
- Letrozole -Berberine, Letrozole, Berberine
- Where
- 18 sites in China
- Volunteers
- 660 people
- Sponsor
- Heilongjiang University of Chinese Medicine
Clomiphene Citrate Resistant Polycystic Ovary Syndrome
NAC in CC Resistant PCOS After LOD
This prospective randomized placebo-controlled double blind clinical trial will conducted in Ain Shams University maternity Hospital including 120 women diagnosed with clomiphene citrate resistant polycystic ovary syndrome.
- Trial name
- NAC (NCT02775734)
- Testing
- N-acetyl-cysteine, Clomiphene citrate
- Where
- Egypt
- Volunteers
- 144 people
- Sponsor
- Ain Shams University
Anovulation, Obesity
An RCT of Metformin Vs Orlistat in Obese Anovulatory Women
This study aims to investigate the role of the weight reduction agent, Orlistat compared to the Metformin for the management of women who are obese and do not ovulate or have difficulty conceiving.
- Trial name
- NCT00292799
- Testing
- Orlistat Vs Metformin
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Polycystic Ovary Syndrome
Evaluation of Serum Prostatic Specific Antigen (PSA) After Cyproterone Compound Treatment Compared With Oral Contraceptives Pill in Hirsute Polycystic Ovary Syndrome Patients
The purpose of this study is to evaluate the effect of oral contraceptive on the serum free prostatic specific antigen (PSA)in women with polycystic ovary syndrome(PCOD)compared with cyproterone compound.
- Trial name
- PSA (NCT00955058)
- Testing
- OCP
- Where
- Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University
Polycystic Ovary Syndrome
Taste Function and Eating Habits in Polycystic Ovary Syndrome
This study evaluates taste function and eating habits in patients with PCOS compared to healthy women and before and after oral contraceptive use.
- Trial name
- NCT04238078
- Testing
- Contraceptive
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Pregnancy, Polycystic Ovary Syndrome
Metformin to Prevent Late Miscarriage and Preterm Delivery in Women With Polycystic Ovary Syndrome
The overall aim of the PregMet 2 Study is to investigate whether metformin prevents late miscarriages and preterm deliveries in PCOS women treated with metformin from first trimester of pregnancy to delivery in a large…
- Trial name
- PregMet2 (NCT01587378)
- Testing
- Metformin
- Where
- 13 sites in Iceland, Norway and 1 more
- Volunteers
- 489 people
- Sponsor
- Norwegian University of Science and Technology
PCOS (Polycystic Ovary Syndrome)
Effects of Folic Acid and Vitamin E on Hormones in Polycystic Ovary Syndrome
The goal of this prospective comparative interventional study is to evaluate serum Ezrin levels and investigate the effects of one-month supplementation with vitamin E and folic acid in Iraqi women of reproductive age diagnosed…
- Trial name
- NCT07723443
- Testing
- Vitamin E 400, Folic Acid 5 Mg Oral Tablet
- Where
- Iraq
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
PCOS (Polycystic Ovary Syndrome)
Anxiety and Depression in Adolescent PCOS
Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder in adolescent females, often accompanied by psychological symptoms such as anxiety and depression. These conditions are frequently underdiagnosed and untreated.
- Trial name
- NCT07127458
- Testing
- Adolescent PCOS group receiving oral contraceptives
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Ege University
Polycystic Ovarian Syndrome, Subfertility
A Comparison of Letrozole and Clomifene Citrate
Polycystic ovary syndrome (PCOS) is one of the most common endocrinopathies, affecting 5% to 10% of women of reproductive age. Women with PCOS suffer from anovulatory infertility.
- Trial name
- NCT02647424
- Testing
- Letrozole, Clomiphene
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- The University of Hong Kong
Induction of Ovulation
Laparoscopic Ovarian Drilling Versus Letrozole In Clomiphene Citrate Resistant Polycystic Ovary
The aim of this work is to compare the clinical outcomes of letrozole with laparoscopic ovarian drilling (LOD) in patients with clomiphene-citrate-resistant polycystic ovary syndrome (PCOS).
- Trial name
- NCT03664050
- Testing
- group A 2.5 mg letrozole oral tablets, laparoscopic ovarian drilling
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Polycystic Ovary Syndrome, Infertility
Live Birth After Fresh Embryo Transfer Vs Frozen-thawed Embryo Transfer in Women With Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women of childbearing age. However, the optimal infertility treatment for PCOS patients is still a matter of controversy.
- Trial name
- FreFro-PCOS (NCT01841528)
- Testing
- fresh embryo transfer, frozen-thawed embryo transfer
- Where
- 14 sites in China
- Volunteers
- 1,180 people
- Sponsor
- Zi-jiang Chen
PCOS (Polycystic Ovary Syndrome)
Comparative Effect of Myo-inositol With That of D-chiro-inositol on Insulin Resistance in Infertile Women With Polycystic Ovary Syndrome (PCOS).
This randomized controlled trial was conducted in the Department of Reproductive Endocrinology and Infertility, BSMMU.A total of 80 infertile women ofPCOS withinsulinresistanceparticipatedinthestudyandwere randomly allocated into…
- Trial name
- PCOS HOMA IR (NCT07453680)
- Testing
- Tab Myo-inositol 750mg, D-chiro-inositol 500mg
- Where
- Bangladesh
- Volunteers
- 80 people
- Sponsor
- Mst.Sumyara Khatun
Polycystic Ovary Syndrome (PCOS)
Blood Vessel Function in Adolescents and Women With Polycystic Ovary Syndrome
The purpose of this study is to determine if changes in blood vessel health lead to the menstrual irregularities that women with PCOS experience.
- Trial name
- NCT01615562
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Insulin Sensitivity
Insulin Sensitivity and Testosterone Response to Aerobic Exercise Versus Added Sugar Elimination in Polycystic Ovary Syndrome Women
the aim of this study is to investigate the effect of aerobic exercise versus the effect of added sugar elimination on the insulin sensitivity and testosterone levels in females with polycystic ovarian syndrome via measuring the…
- Trial name
- NCT07139275
- Testing
- aerobic exercise, added sugar elimination, aerobic exercise and added sugar elimination
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
PCOS
Cabergoline & Letrozole Versus Letrozole in Ovulation Induction in PCOS
Does combined Cabergoline and letrozole increase ovulation rate What medical problems do participants have when taking drug Cabergoline and Letrozole ? Researchers will compare drug combination of Cabergoline and letrozole to…
- Trial name
- PCOS OID (NCT07255911)
- Testing
- Letrozole 0.5mg, Cabergoline 0.5 mg
- Where
- Bangladesh
- Volunteers
- 72 people
- Sponsor
- Mst.Sumyara Khatun
Polycystic Ovary Syndrome, Body Weight
Weight Maintenance With Dipeptidyl Peptidase 4 (DPP4) Inhibitor Sitagliptin in Combination With Metformin After Liragludite Induced Weight Loss
Weight reduction is the most important treatment target in obese women with polycystic ovary syndrome (PCOS), yet it is usually hardly achievable with lifestyle intervention alone.
- Trial name
- NCT02941445
- Testing
- sitagliptin and metformin, Metformin
- Volunteers
- 24 people
- Sponsor
- University Medical Centre Ljubljana
Polycystic Ovary Syndrome (PCOS), Betatrophin
Serum Betatrophin Levels in Normal-Weight and Overweight Adolescents With PCOS
Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder in adolescents and women of reproductive age and is frequently associated with insulin resistance and an increased risk of metabolic complications.
- Conditions
- Polycystic Ovary Syndrome (PCOS), Betatrophin, Body Mass Index (BMI), Insulin Resistance
- Trial name
- NCT07480993
- Testing
- Serum betatrophin levels
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
PCOS, PCOS (Polycystic Ovary Syndrome)
PMOS in OSA Pilot Study
The goal of this study is to obtain pilot data investigating the effects of sleep apnea on mitochondrial function and cellular metabolism in Polyendocrine Metabolic Ovarian Syndrome (PMOS) patients.
- Conditions
- PCOS, PCOS (Polycystic Ovary Syndrome), OSA, OSA - Obstructive Sleep Apnea
- Trial name
- NCT07871149
- Testing
- Continuous Positive Airway Pressure (CPAP)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Chicago
PCOS, Hyperandrogenism
Ultrasound Three-dimensional Characterization of Ovarian Morphology in Women With Polycystic Ovary Syndrome (PCOS)
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders occurring in women of reproductive age. PCOS is considered a syndrome of ovarian dysfunction that is characterized by the heterogeneous clinical…
- Trial name
- NCT02402413
- Testing
- Ultrasound, Determination of concentrations of androgens, Three dimensional ultrasound probe
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
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