Clinical trials: Polycystic Ovary Syndrome
Polycystic Ovarian Syndrome
The Relationship Between Adipokines, Obesity and Insulin Resistance in Women With Polycystic Ovarian Syndrome
To evaluate possible clinical effects of adipokines , ( ghrelin, resistin and adiponectin), in obese and non-obese patients with polycystic ovary syndrome (PCOS).
- Trial name
- NCT02869750
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
PCOS
Role of Nesfatin-1 and Nicotinamide in Infertile Women With Polycystic Ovary Syndrome
evaluation of the potential role of circulating Nesfatin-1 and Nicotinamide in patients with polycystic ovary syndrome. and detection the correlation between Nesfatin-1 and body mass index (BMI), Waist hip ratio (WHR), blood…
- Trial name
- NCT03870035
- Volunteers
- 56 people
- Sponsor
- Assiut University
Polycystic Ovarian Syndrome, Vitamin D Deficiency
Health Benefits of Vitamin D and Calcium in Women With PCOS (Polycystic Ovarian Syndrome)
The investigators conducted a prospective un-blinded pilot study of Vitamin D plus Calcium (Ca) supplementation in overweight (BMI > 27) premenopausal women diagnosed with Polycystic Ovarian Syndrome (PCOS), as defined by the…
- Trial name
- NCT00743574
- Testing
- Vitamin D2 (Ergocalciferol), Medroxyprogesterone (Provera), Vitamin D3 (Cholecalciferol)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Yale University
PCOS (Polycystic Ovary Syndrome), Puberty
ActiveGirls: Physical Activity, Hormone Health, and Diabetes Risk in Early Adolescence
This study explores how a physical activity program can affect hormone health and diabetes risk in girls ages 8-12 who may be at higher risk.
- Conditions
- PCOS (Polycystic Ovary Syndrome), Puberty, Insulin Resistance, Physical Activity
- Trial name
- NCT07102797
- Testing
- ActiveGirls Physical Activity Program (Full), ActiveGirls Physical Activity Program (Delayed Lower Intensity)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Massachusetts General Hospital
Polycystic Ovary Syndrome
Novel Subtypes of Polycystic Ovary Syndrome
To classify subtypes of Polycystic Ovary Syndrome (PCOS) using machine-learning algorithms, and compare the reproductive and metabolic characteristics and IVF outcomes across these identified subtypes.
- Trial name
- NCT06124391
- Testing
- Long-term follow-up
- Where
- 11 sites in United States, Brazil and 4 more
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- Shandong University
Polycystic Ovary Syndrome (PCOS) Women
Metformin Effects on Metabolic, Vitamin B12, Iron, Erythropoietin, and Hematological Parameters in Women With PCOS
This double-blind, placebo-controlled, parallel-group randomized controlled trial evaluated changes in metabolic, vitamin B12, iron-status, erythropoietic, and hematological parameters among women with polycystic ovary syndrome…
- Trial name
- MET-PCOS (NCT07793838)
- Testing
- Metformin
- Where
- Jordan
- Volunteers
- 400 people
- Sponsor
- Jerash Private University
Polycystic Ovary Syndrome
Low Dose OC Therapy in Women With Polycystic Ovary Syndrome (PCOS): Impact of BMI on Hyperandrogenism
The classic description of polycystic ovary syndrome (PCOS) is that it is a disorder characterized by menstrual irregularity, chronic anovulation, androgen excess, and abnormal gonadotropin secretion.
- Trial name
- BEYAZ-PCOS (NCT01360996)
- Testing
- 3 mg DRSP/20 μg EE
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Woman's
PCOS (Polycystic Ovary Syndrome)
MeDiApp-PCOS: A Mobile Mediterranean Diet App for Women With Polycystic Ovary Syndrome
This randomized clinical trial will test whether a mobile application with personalized Mediterranean diet-based recommendations can improve health outcomes in women with polycystic ovary syndrome compared with standard lifestyle…
- Trial name
- MeDiApp-PCOS (NCT07598344)
- Testing
- Mobile Application-Based Personalized Mediterranean Diet and Lifestyle Intervention, Standard Lifestyle Advice for PCOS
- Volunteers
- 60 people
- Sponsor
- Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health
Infertility, Polycystic Ovarian Syndrome
LOD Before IVF/ICSI in PCOS Patients With High AMH
To evaluate the effect of performing laparoscopic ovarian drilling (LOD) before proceeding to in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) on the cycle outcomes in polycystic ovarian syndrome (PCOS)…
- Trial name
- NCT03358199
- Testing
- LOD
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Mansoura University
Polycystic Ovary Syndrome (PCOS), Female Endocrine Disorder
A Study of AZD4901 in Females With Polycystic Ovary Syndrome
To assess the effects of AZD4901 when given in multiple doses to females with Polycystic Ovary Syndrome
- Trial name
- NCT01872078
- Testing
- AZD4901 (oral)
- Where
- 7 sites in United States, Germany and 1 more
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Acanthosis Nigricans, Polycystic Ovary Syndrome
Phase II Study of the Effect of Leuprolide Acetate and Spironolactone on Insulin Resistance in Hyperandrogenic Women With Polycystic Ovarian Disease or Hyperandrogenism Insulin Resistance Acanthosis Nigricans Syndrome
OBJECTIVES: I. Evaluate insulin resistance in thin and obese hyperandrogenic women with polycystic ovarian disease or hyperandrogenism insulin resistance acanthosis nigricans syndrome and in thin and obese controls, using an…
- Trial name
- NCT00004311
- Testing
- leuprolide acetate, spironolactone
- Sponsor
- National Center for Research Resources (NCRR)
Infertility
The Effect of Ethinyl Estradiol on Polycystic Ovary Syndrome Women Undergoing Intrauterine Insemination
According to the studies CC is successful at inducing ovulation in 50%-75% of cases, but only 30-40% becomes pregnant. The difference has been attributed to a negative action of clomifen citrate(CC) in the form of prolonged…
- Trial name
- NCT01219101
- Testing
- clomiphene citrate with ethinyl esteradiol, clomiphene citrate with plasebo
- Where
- Iran
- Volunteers
- 95 people
- Sponsor
- Royan Institute
Anovulation
Predictors of Ovarian Response During Clomiphene Citrate Ovulation Induction in Patients With Polycystic Ovary Syndrome
The purpose of this study is to determine whether Visceral fat area and other criteria assessed during initial screening could predict the response to ovulation induction with clomiphene citrate (CC) in patients with polycystic…
- Trial name
- NCT02269306
- Testing
- clomiphen citrate
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Menoufia Obstetrics and Gynecology Group
Polycystic Ovary Syndrome
Theca Cell Function in Women With Polycystic Ovary Syndrome (PCOS)
The mechanism for increased androgen production in women with polycystic ovary syndrome (PCOS) is not well understood. Excess androgen production by the ovary is stimulated by increased pituitary luteinizing hormone (LH)…
- Trial name
- NCT00747617
- Testing
- recombinant human chorionic gonadotropin
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Polycystic Ovary Syndrome, Overweight
Clinical Sciences Research Proposal- The Effect of Physical Exercise on PCOS Overweight Female Adolescents
The Poly Cystic Ovary Syndrome (PCOS), is one of the most common reasons for subfertility, oligomenorrhea and amenorrhea. With the occurrence of 6-20% of the general adult women population.
- Trial name
- NCT03068221
- Testing
- anaerobic exercise
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Anovulatory Infertility, Abnormal Uterine Bleeding-Ovulatory Disorders
Effectiveness and Safety of Bushen Culuan Decoction for Anovulatory Infertility
This study is to evaluate the effectiveness and safety of Bushen Culuan Decoction in the treatment of anovulatory infertility, including anovulatory abnormal uterine bleeding, polycystic ovarian syndrome, hyperprolactinemia…
- Conditions
- Anovulatory Infertility, Abnormal Uterine Bleeding-Ovulatory Disorders, Polycystic Ovarian Syndrome, Hyperprolactinemia
- Trial name
- NCT03709849
- Volunteers
- 528 people
- Sponsor
- Xiyuan Hospital of China Academy of Chinese Medical Sciences
PCOS
Eye Evaluation in Patients With PCOS
To evaluate the macular, retinal nerve fiber layer (RNFL) and choroidal thickness alterations by using spectral-domain optical coherence tomography (SD-OCT) in polycystic ovary syndrome (PCOS) and to compare them with healthy…
- Trial name
- NCT01950832
- Testing
- Investigating clinically normal patients with optic coherence tomography
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Gökhan Açmaz
PCOS, Vitamin D
Effect of Vitamin D Supplementation on Testosterone Level in Women With Polycystic Ovary Syndrome
The goal of this randomized, double blind, placebo-controlled clinical trial is to learn about, the effect of low dose vitamin D supplementation compares with placebo-controlled group on testosterone level in women with…
- Trial name
- NCT06101147
- Testing
- Vitamin D3
- Where
- Bangladesh
- Volunteers
- 66 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Pregnancy, Polycystic Ovary Syndrome
Metformin to Prevent Late Miscarriage and Preterm Delivery in Women With Polycystic Ovary Syndrome
The overall aim of the PregMet 2 Study is to investigate whether metformin prevents late miscarriages and preterm deliveries in PCOS women treated with metformin from first trimester of pregnancy to delivery in a large…
- Trial name
- PregMet2 (NCT01587378)
- Testing
- Metformin
- Where
- 13 sites in Iceland, Norway and 1 more
- Volunteers
- 489 people
- Sponsor
- Norwegian University of Science and Technology
Polycystic Ovarian Syndrome (PCOS), Reproductive Health
Management of Polycystic Ovarian Syndrome-associated Reproductive Dysfunction Through Kefir Supplementation
Polycystic ovary syndrome (PCOS) affect around 6-12% of women of age 18-25 years. Kefir contains bioactive compounds such as lactic acid bacteria, yeast, peptides, polysaccharides and organic acids and acts as a good probiotic…
- Trial name
- NCT07711782
- Testing
- (C0) Control group, (G1) Experimental group
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- University of Lahore
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