Clinical trials: Polycystic Ovary Syndrome (PCOS)
Polycystic Ovarian Syndrome, Idiopathic Intracranial Hypertension
Astronaut Vision Issues in a Ground Analog Population: Polycystic Ovary Syndrome
The investigators have documented a genetic predisposition for some astronauts to develop ophthalmologic issues (e.g., choroidal folds, cotton wool spots, optic disc edema).
- Trial name
- PCOS (NCT02896452)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Aeronautics and Space Administration
Infertility
Influence of a Prematuration Culture With a Phosphodiesterase-3 Inhibitor (PDE3-I) on Embryonic Aneuploidy Rate and Developmental Potential
A single centre randomised controlled trial investigating the influence of a novel prematuration system (PMS) using a phosphodiesterase-3 inhibitor for in-vitro maturation of oocytes - pilot study.
- Trial name
- NCT00822874
- Testing
- prematuration culture
- Where
- Belgium
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Polycystic Ovary Syndrome
Targeting Pathways in Polycystic Ovary Syndrome (PCOS) Using Metformin (MET)
The investigator's global hypothesis is that women with Polycystic Ovary Syndrome (PCOS) can be separated into subtypes based on their response to metformin.
- Trial name
- NCT02086526
- Testing
- Metformin
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Mayo Clinic
Polycystic Ovary Syndrome, Overweight
Time-restricted Feeding for Treating Polycystic Ovary Syndrome (PCOS)
Intermittent fasting is an increasingly popular diet pattern of alternating eating and dieting.One particular form of intermittent fasting is the so-called time-restricted feeding (TRF).
- Conditions
- Polycystic Ovary Syndrome, Overweight, Obesity
- Trial name
- PCOS (NCT04580433)
- Testing
- Time-Restricted Feeding
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Chunzhu Li
Polycystic Ovary Syndrome Health-related Quality of Life
Translation and Validation of the French mPCOSQ (mPCOSQ-F).
This study is a prospective, observational, bicentric study, evaluating the validity and reliability of a French version of the mPCOSQ questionnaire (mPCOSQ-F), used to assess health-related quality of life (HRQOL) in women with…
- Trial name
- NCT07016035
- Testing
- mPCOSQ-F and SF-36
- Where
- France
- Volunteers
- 350 people
- Sponsor
- CHU de Reims
Hyperandrogenism, Insulin Resistance
Meal Timing on Glucose Metabolism and Hyperandrogenism in Lean Women With Polycystic Ovary Syndrome
In obese women with polycystic ovary syndrome (PCOS), weight loss improves insulin resistance and hyperandrogenism, resulting in improvement of clinical symptoms.
- Trial name
- M-PCOS (NCT01569425)
- Testing
- Dietary intervention
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Tel Aviv University
Polycystic Ovary Syndrome, Metabolic Syndrome
Metabolic Syndrome in PCOS: Precursors and Interventions
The purpose of this study is to investigate the metabolic effects of anti-androgens and oral contraceptive pills (OCPs), compared with placebo, in the treatment of women with PCOS.
- Trial name
- NCT00442689
- Testing
- flutamide, ethinyl estradiol 35 mcg and drospirenone 3 mg
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Northwestern University
Infertility
Extended Clomiphene Citrate Regimen in Women With Polycystic Ovary Syndrome
One hundred and thirty six anovulatory women with CC-resistant PCOS were scheduled randomly into two equal groups. Group A (n=68); received CC (100 mg/day from cycle day 3 for 10 days) for up to six cycles.
- Trial name
- NCT02381184
- Testing
- clomiphene citrate, laparoscopic ovarian drilling (LOD)
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Benha University
Polycystic Ovary Syndrome
The Secretion of Incretin Hormones in Patients With Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is an endocrine disease in reproductive women. It is characterized by anovulation and hyperandrogenism.
- Trial name
- NCT02126592
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Polycystic Ovary Syndrome, Infertility
New Application of Sequential in Vitro Muturation System for Infertility Patients With Polycystic Ovary Syndrome
Oocyte in vitro maturation (IVM) is an artificial reproductive technologies (ART) in which cumulus-oocyte complex (COC) are collected at the immature germinal vesicle (GV) stage from unstimulated or FSH-primed ovaries and matured…
- Trial name
- NCT03773263
- Testing
- sequential IVM system, intracytoplasmic sperm injection (ICSI), Thawed embryo transfer (TET)
- Where
- 5 sites in China
- Volunteers
- 300 people
- Sponsor
- Sun Yat-sen University
Polycystic Ovary Disease
"KETOGENIC MEDITERRANEAN VERSUS HYPOCALORIC BALANCED DIET ON POLYCYSTIC OVARIAN ADOLESCENTS"
study was designed to determine the effect of ketogenic Mediterranean diet versus hypocaloric balanced diet on adolescent female with polycystic ovary disease.
- Trial name
- keto- MEDITERR (NCT06610812)
- Testing
- KETOGENIC MEDITERRANEAN diet, hypo-caloric diet:, moderate aerobic exercises
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- MTI University
Polycystic Ovary Syndrome
A Trial of Personalized Acupuncture, Fixed Acupuncture, Letrozole and Placebo on Live Birth in Women With PCOS
This study is a randomized assessor-blind controlled trial. A total of 1,103 women with PCOS will be recruited from 20 hospitals and randomly allocated into four groups: personalized acupuncture, fixed acupuncture, letrozole or…
- Trial name
- NCT03625531
- Testing
- Acupuncture, Letrozole
- Where
- China
- Volunteers
- 1,103 people
- Sponsor
- Hongxia Ma
Sterility, Infertility
Myo-Inositol- Based Co-treatment in Women With PCOS Undergoing Assisted Reproductive Technology
This is a prospective comparative randomized controlled study investigating the effect of Myo-Inositol-based co-treatment on oocyte quality measures in women with PCOS.
- Trial name
- NCT03177122
- Testing
- Myo-inositol
- Where
- Lebanon
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Polycystic Ovary Syndrome
Evaluation of the Venous Thrombotic Biological Profile of Different PCOS Phenotypes: French Cross-sectional Study
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder of women of childbearing age. PCOS can be individualized into several phenotypes, taking into account in particular the presence of hyperandrogenism, insulin…
- Trial name
- Hemo-PCOS (NCT06339567)
- Testing
- Thrombotic profile
- Where
- France
- Volunteers
- 352 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Polycystic Ovary Syndrome
A Reduced Carbohydrate Diet Intervention for Polycystic Ovary Syndrome (PCOS)
Polycystic ovary syndrome (PCOS) affects 5-10% of women of reproductive age, and is associated with infertility, risk for obesity and type 2 diabetes, and impaired quality of life.
- Trial name
- NCT01028989
- Testing
- Reduced Glycemic Load Diet, Standard Diet
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Polycystic Ovarian Syndrome
Effects of Fasting Mimicking Diet (FMD) in Women With Polycystic Ovary Syndrome (PCOS)
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in reproductive-aged women, affecting 6-21% (depending on the applied diagnostic criteria) of this population worldwide.
- Trial name
- NCT05196568
- Testing
- Fasting mimicking diet
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Salento
Subfertility, Assisted Reproduction
Evaluation of the Role of Follicular Sensitivity Index in the Prediction of Pregnancy in Women Undergoing ICSI/IVF Without Polycystic Ovarian Syndrome
1000 women with infertility who are already decided to be treated with ICSI will be subjected to full history taking and clinical examination.
- Trial name
- NCT02158026
- Where
- 2 sites in Egypt
- Volunteers
- 1,000 people
- Sponsor
- Cairo University
Polycystic Ovary Syndrome, PCOS
Insulin Differences Between African-American and Caucasian Female Adolescents With Polycystic Ovary Syndrome (PCOS)
The purpose of this research study is to see if there are differences between African-American and Caucasian girls with Polycystic Ovary Syndrome (PCOS) in how their bodies respond to a type of sugar, called glucose, the body's…
- Trial name
- NCT02052479
- Testing
- Frequently Sampled Intravenous Glucose Tolerance Test (FSIVGTT)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Nationwide Children's Hospital
Polycystic Ovary Syndrome, Vitamin D Deficiency
30000 IU Per Week Vitamin D Treatment in PCOS Patients
This is a human, II/b phase, multicentre, randomised, double blind, placebo-controlled study to assess the safety and the efficacy of a weekly administered dose of 30,000 IU vitamin D (colecalciferol) in deficient patients…
- Trial name
- NCT04840238
- Testing
- Cholecalciferol
- Where
- 8 sites in Hungary
- Volunteers
- 115 people
- Sponsor
- Semmelweis University
Polycystic Ovary Syndrome, Exercise
The Effects of High-intensity and Moderate-intensity Exercise on Polycystic Ovary Syndrome
This study will investigate the impact of high- and moderate-intensity exercise on the cardiometabolic and brain health of women with Polycystic Ovary syndrome (PCOS).
- Conditions
- Polycystic Ovary Syndrome, Exercise, Cerebrovascular Circulation
- Trial name
- NCT05394935
- Testing
- High-Intensity Exercise, Moderate-Intensity Exercise
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cardiff Metropolitan University
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