Clinical trials: Polyethylene Glycol With Ascorbic Acid
Bowel Preparation Solution
PEG-Asc Vs. SPMC for Bowel Preparation in Capsule-based Procedures
This clinical research study is designed to find out which of two different types of bowel preparation works best for people undergoing capsule-based endoscopy procedures.
- Trial name
- NCT07206329
- Testing
- Polyethylene Glycol plus Ascorbic Acid (PEG-Asc), Sodium Picosulfate with Magnesium Citrate (SPMC)
- Where
- Portugal
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Unidade Local de Saúde do Alto Ave, EPE
Bowel Preparation
Effectiveness of Bisacodyl Suppository Agent for Dose Reduction of Low Dose PEG
Proper bowel cleansing before colonoscopy is an important factor to increase the detection rate of lesions. Low volume polyethylene glycol (PEG) plus ascorbic (PEG-Asc) has reduced the dosage of previous bowel preparation agent…
- Trial name
- NCT03849196
- Testing
- 2L PEG-Asc, Bisacodyl 10Mg Suppository, 1L PEG-Asc
- Where
- South Korea
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Colon Cancer, Colon Disease
Real Word Evidence With 1L Polyethylene Glycol (PEG)+ Ascorbic Acid in Iberia
A retrospective study to evaluate the effectiveness and safety of 1L polyethylene glycol (PEG)+ Ascorbic acid given for bowel preparation before colonoscopy.
- Conditions
- Colon Cancer, Colon Disease, Colon Cleansing
- Trial name
- NCT05174845
- Testing
- 1L PEG + ASCORBIC ACID
- Where
- 12 sites in Portugal, Spain
- Volunteers
- 13,393 people
- Sponsor
- Norgine
Healthy
Comparison of Polyethylene Glycol With Ascorbic Acid and Oral Sulfate Solution for Bowel Preparation
Colonoscopy is considered by many the preferred mode of screening for colorectal cancer (CRC). The effectiveness of any CRC screening program is critically dependent on an adequate bowel preparation.
- Trial name
- NCT02551198
- Testing
- HAPREP®, SUCLEAR®
- Where
- South Korea
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- National Cancer Center, Korea
Bowel Disease, Colon Adenoma
Comparison of Low Volume PEG-Asc and Lower Volume PEG-Asc With Bisacodyl
Recently a low-volume polyethylene glycol containing ascorbic acid (PEG-Asc) formulation has proven as safe and effective as traditional 4-L PEG solutions for colonoscopy preparation.
- Trial name
- NCT02980562
- Testing
- Polyethylene Glycols, Bisacodyl
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Colonoscopy Preparation
Colon Cleansing Quality of Polyethylene Glycol Compared With Polyethylene Glycol Plus Ascorbic Acid.
The purpose of the study is to assess whether a low volume polyethylene glycol (PEG) plus ascorbic acid based bowel preparation for colonoscopy is not inferior to a large volume polyethylene glycol preparation in subjects with…
- Trial name
- REPREP1 (NCT02073552)
- Testing
- Polyethylene glycol 4000, Macrogol 3350 plus ascorbic acid
- Where
- Spain
- Volunteers
- 472 people
- Sponsor
- Fundación Canaria Rafael Clavijo para la Investigación Biomédica
Colon Cleansing for Colonoscopy
Sodium Picosulphate/Magnesium Citrate and Low-volume PEG -Ascorbic Acid as Preparation for Colonoscopy
Adequate bowel cleansing is essential for effective colonoscopy. Acceptance of colon preparation affects the quality of colon cleansing.
- Trial name
- NCT01603654
- Testing
- sodium picosulphate magnesium citrate, low-volume PEG -ascorbic acid
- Where
- 3 sites in Italy
- Volunteers
- 300 people
- Sponsor
- ASST Fatebenefratelli Sacco
Colorectal Cancer, Colon Adenoma
A Randomized Prospective Trial Comparing Low-volume Bowel Preparation Methods
Colonoscopy is a common screening method to detect polyps and CRC. With the early detection of CRC through screening colonoscopy, patients could have better therapeutic effects and outcomes.
- Trial name
- NCT02250196
- Testing
- PEG-Asc, SPMC 2
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Korea University Anam Hospital
Colonoscopy
Comparison Between OSS and 2L PEG/Asc for Bowel Preparation of Elderly People
For evaluation of the usefulness of oral sulfate solution (OSS) for bowel preparation of elderly people, investigators compare the efficacy, tolerability and safety between OSS and 2L polyethylene glycol (PEG) with ascorbic acid…
- Trial name
- NCT03520361
- Testing
- Oral sulfate solution (OSS), 2L PEG/Asc
- Where
- South Korea
- Volunteers
- 198 people
- Sponsor
- KangWon National University Hospital
Cathartic Colon
Oral Sulfate Solution (SUPREP) Versus Polyethylene Glycol (PEG) Plus Ascorbic Acid
The aims of the present study is to compare oral sulfate solution (OSS) with low-dose polyethylene glycol plus ascorbic acid (2-L PEG/Asc) for bowel cleansing efficacy.
- Trial name
- NCT02761213
- Testing
- Oral sulfate solution (OSS), 2-L PEG/Asc
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bo-In Lee
Colonoscopy, Colon Polyp
The Effect of 1L Polyethylene Glycol Plus Ascorbic Acid With Prepackaged Low-Residue Diet for Bowel Preparation
Background 2L polyethylene glycol plus ascorbic acid (PEGA) is known to be as effective as standard 4L polyethylene glycol for bowel preparation. However, the volume of this regimen is still large.
- Conditions
- Colonoscopy, Colon Polyp, Bowel Preparation Solutions
- Trial name
- NCT03329339
- Testing
- 1 L PEG with ascorbic acid with prepackaged, low residue diet
- Volunteers
- 200 people
- Sponsor
- Seoul National University Bundang Hospital
Stasis; Colon
Comparison Between Coolprep and Picolyte for Bowel Cleansing
The investigators will compare with PEG+ascorbic acid and picosulfate+magnesium citrate about bowel preparation, patient's satisfaction, side effects to identify effectiveness of new bowel preparation drug.
- Trial name
- NCT01774175
- Volunteers
- 250 people
- Sponsor
- Gachon University Gil Medical Center
Colorectal Cancer
Effect of Simethicone on Bowel Preparation for Colonoscopy
Optimal bowel preparation is essential for colonoscopy efficacy and safety. Mucosal visualization during colonoscopy is often limited by residual stool, bubbles, bile, intraluminal fluid, and debris, which increase the risk of…
- Trial name
- NCT02548403
- Testing
- PEG-Asc, PEG-Asc with simethicone
- Where
- South Korea
- Volunteers
- 260 people
- Sponsor
- Korea University Anam Hospital
Bowel Preparation, Sodium Picosulfate and Magnesium Citrate
Combination Method Using Sodium Picosulfate and Magnesium Citrate and PEG With Ascorbic Acid for Bowel Preparation
The aim of this study is to compare the efficacy depending on the order of the sequential combination method using sodium picosulfate and magnesium citrate (PMC) and PEG with ascorbic acid for bowel preparation.
- Conditions
- Bowel Preparation, Sodium Picosulfate and Magnesium Citrate, Polyethylene Glycol With Ascorbic Acid
- Trial name
- NCT02979223
- Testing
- sodium picosulfate and magnesium citrate, polyethylene glycol with ascorbic acid
- Where
- South Korea
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- National Cancer Center, Korea
Bowel Preparation, Colonoscopy
Bowel Preparation for Colonoscopy in the Elderly
The success of colonoscopy is closely related to the quality of colonic preparation. However, data regarding colonoscopy preparations in the elderly (65 years older) are scarce.
- Trial name
- NCT02290093
- Testing
- Standard full-volume PEG, Split-dose full-volume PEG, Split-dose low-volume PEG
- Where
- 3 sites in South Korea
- Volunteers
- 230 people
- Sponsor
- Kyunghee University Medical Center
Diabetes Mellitus, Colonic Diseases
Improvement of Tolerance of Bowel Cleansing Before Colonoscopy in Diabetic Patients
This trial will compare the tolerance to 2 different methods for colon cleansing before colonoscopy in diabetic patients.
- Trial name
- iDIMEPREP (NCT02297399)
- Testing
- PEG-ascorbate 2L, PEG 4L
- Where
- 2 sites in Spain
- Volunteers
- 158 people
- Sponsor
- Parc de Salut Mar
Ulcerative Colitis
Tolerability and Efficacy of Sodium Picosulfate/Magnesium Citrate Versus PEG/Ascorbic Acid in Ulcerative Colitis Patients
Ulcerative colitis is a chronic condition that results in the inflammation of the colon and rectum. Patients suspected to have ulcerative colitis are diagnosed via colonoscopy.
- Trial name
- NCT03581149
- Testing
- Sodium Picosulfate/Magnesium Citrate Laxative, 2L polyethylene glycol/ascorbic acid
- Where
- Lebanon
- Volunteers
- 68 people
- Sponsor
- American University of Beirut Medical Center
Ulcerative Colitis
Comparison of 4L Polyethylene Glycol and 2L Polyethylene Glycol With Ascorbic Acid in Inactive UC Patients
The purpose of this study is to compare preference of the patients, efficacy of preparation, and safety between 4 L polyethylene glycol and 2 L of polyethylene glycol with ascorbic acid in patients with inactive ulcerative…
- Trial name
- 2SCANI (NCT01929668)
- Testing
- polyethylene glycol, Ascorbic Acid
- Where
- South Korea
- Volunteers
- 114 people
- Sponsor
- Kyungpook National University Hospital