Clinical trials: Polyethylene Glycols
Ulcerative Colitis
Comparison of 4L Polyethylene Glycol and 2L Polyethylene Glycol With Ascorbic Acid in Inactive UC Patients
The purpose of this study is to compare preference of the patients, efficacy of preparation, and safety between 4 L polyethylene glycol and 2 L of polyethylene glycol with ascorbic acid in patients with inactive ulcerative…
- Trial name
- 2SCANI (NCT01929668)
- Testing
- polyethylene glycol, Ascorbic Acid
- Where
- South Korea
- Volunteers
- 114 people
- Sponsor
- Kyungpook National University Hospital
Melanoma, Neoplasm Metastasis
ADI-PEG in Patients With Metastatic Melanoma
This is a study to determine the safety and toxicity of increasing doses of arginine deiminase combined to polyethylene glycol (ADI-PEG) in patients with nonresectable metastatic melanoma.
- Trial name
- NCT00029900
- Testing
- ADI PEG
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- FDA Office of Orphan Products Development
Anemia, Kidney Disease, Chronic
A Retrospective Observational Study of Hemoglobin Levels in Patients With Renal Anemia Treated With Mircera (Methoxy Polyethylene Glycol-Epoetin Beta)
This retrospective observational study will evaluate the hemoglobin levels in patients with renal anemia over 6 months treatment with Mircera (methoxy polyethylene glycol-epoetin beta).
- Trial name
- NCT01379963
- Where
- 17 sites in Greece
- Volunteers
- 780 people
- Sponsor
- Hoffmann-La Roche
Genital Herpes
A Study to Investigate the Efficacy, Safety and Tolerability of PEG in Patients With Genital Herpes
The aim of this study is therefore to investigate the efficacy of the PEG-formulation to reduce the frequency and duration of genital herpes recurrences, to assess its safety and tolerability and to investigate its effect on…
- Trial name
- NCT01765114
- Testing
- PEG-Formulation
- Where
- Switzerland
- Volunteers
- 8 people
- Sponsor
- Devirex AG
Constipation
Efficacy and Safety of Polyethylene Glycol 3350 (PEG 3350) for Relief of Constipation (MK-8114-005)
The purpose of this study is to evaluate the complete resolution of constipation in participants taking PEG 3350 compared to those taking PEG 4000, based on analysis of the number of bowel movements from self-reported bowel…
- Trial name
- NCT02292459
- Testing
- Polyethylene Glycol 3350 Powder for Solution (PEG 3350), Polyethylene Glycol 4000 Powder for Solution (PEG 4000)
- Sponsor
- Bayer
Bowel Preparation
Efficacy and Safety of Polyethylene Glycol Compared With Sodium Picosulphate for Bowel Preparation Before Colonoscopy
Patients intended for ambulatory colonoscopy will be randomized into 2 groups
- Trial name
- NCT01093274
- Testing
- Sodium Picosulphate, Polyethylene Glycol
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Rabin Medical Center
Bowel Preparation Before Colonoscopy
Improved Bowel Cleansing Method for Colonoscopy Based on High Risk Population of Bowel Preparation
The purpose of this study is to observe the difference in bowel preparation quality between compound sodium picosulfate#CSP combined with lactulose and polyethylene glycol electrolyte#PEG combined with lactulose in high-risk…
- Trial name
- NCT05498714
- Testing
- PEG+lactulose, CSP＋lactulose
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Renmin Hospital of Wuhan University
Colonoscopy Preparation
Bowel Preparation for Colonoscopy in Children
The primary objective of this study is to determine whether Miralax results in a more efficacious preparation as compared to senna for pediatric colonoscopy.
- Trial name
- NCT01140295
- Testing
- polyethylene glycol, senna
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Children's Hospital of Philadelphia
Cancer
A Study Comparing Pegylated Filgrastim and Filgrastim in Support for Chemotherapy
Neutropenia is one of the most frequent adverse effects of chemotherapy, and the main factor to limit the dosage and delay the schedule of chemotherapy.
- Trial name
- NCT01285219
- Testing
- pegylated filgrastim and filgrastim, filgrastim and pegylated filgrastim
- Volunteers
- 337 people
- Sponsor
- Chinese Academy of Medical Sciences
Constipation, Surgical Procedure, Unspecified
Pre-operative Polyethylene Glycol 3350 for Minimally Invasive Urogynecologic Surgery
The goal of this clinical trial is to test the use of a laxative before surgery in women having surgery to fix pelvic prolapse that do not have constipation.
- Conditions
- Constipation, Surgical Procedure, Unspecified, Prolapse; Female
- Trial name
- NCT06159777
- Testing
- Polyethylene Glycol 3350
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University Hospitals Cleveland Medical Center
Colonoscopy
Effectiveness of Gum Chewing on Polyethylene Glycol Related Intake Adherence, GI Side Effects and Bowel Preparation
Problem statement An Experimental Study to assess the effectiveness of Gum Chewing on Polyethylene Glycol (PEG) Related Intake Adherence, GI Side Effects and Bowel Preparation among Patients Undergoing Colonoscopy at ILBS, New…
- Trial name
- NCT05328219
- Testing
- Chewing gums with PEG solution, Standard of care
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Constipation
Randomized, Double-Blinded, Placebo-Controlled Trial of Laxatives for Children With Urge Syndrome
HYPOTHESIS: Is MiraLAX an effective treatment of pediatric urinary urge syndrome? OBJECTIVE: Polyethylene glycol (PEG) is common first-line therapy for urinary symptoms despite minimal evidence-based support.
- Trial name
- NCT00765557
- Testing
- MiraLAX
- Volunteers
- 138 people
- Sponsor
- University of Texas Southwestern Medical Center
Hepatic Encephalopathy
PEG (Polyethylene Glycol)Versus Lactulose For Treatment Of Overt Hepatic Encephalopathy
The current standard of care for patients with HE includes non-absorbable disaccharides(lactulose);The chemical name for lactulose is 4-O-β-D-galactopyranosyl-D-fructofuranose.The exact mode of action by lactulose is thought to…
- Trial name
- NCT03100513
- Testing
- Lactulose, Polyethylene Glycol
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sherief Abd-Elsalam
Bowel Preparation Before Colonoscopy
Improved Bowel Preparation Method for Colonoscopy Based on Different Risk Stratification
The purpose of this study is to evaluate the efficacy of polyethylene glycol（PEG） combined with lactulose for bowel preparation before colonoscopy in low-risk patients and high-risk patients.
- Trial name
- NCT04582942
- Testing
- PEG, PEG+lactulose
- Where
- China
- Volunteers
- 2,028 people, healthy volunteers welcome
- Sponsor
- Renmin Hospital of Wuhan University
Healthy
Comparison of Polyethylene Glycol With Ascorbic Acid and Oral Sulfate Solution for Bowel Preparation
Colonoscopy is considered by many the preferred mode of screening for colorectal cancer (CRC). The effectiveness of any CRC screening program is critically dependent on an adequate bowel preparation.
- Trial name
- NCT02551198
- Testing
- HAPREP®, SUCLEAR®
- Where
- South Korea
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- National Cancer Center, Korea
HIV Infections
The Safety and Effectiveness of a Type of Interleukin-2 Plus Zidovudine Plus Thymosin in HIV-Positive Patients With and Without Symptoms of Infection
To determine the safety of thymosin alpha 1 given twice weekly in a regimen of daily oral zidovudine (AZT) and biweekly polyethylene glycolated interleukin-2 (PEG IL-2).
- Trial name
- NCT00001036
- Testing
- Thymalfasin, Interleukin-2, Polyethylene Glycolated, Zidovudine
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Dry Eye
Bilateral, Masked Comparison of PEG-400 Based Artificial Tear and Systane for the Treatment of Dry Eye Signs, Symptoms and Visual Quality
To evaluate and compare the effects of PEG-400 based artificial tear and Systane tears in mild-moderate dry eye patients. TBUT, Visual impact and subjective evaluations will be assessed in this month long trial.
- Trial name
- NCT00622037
- Testing
- PEG-400 based artificial tear, Systane
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bp Consulting, Inc
Kidney Transplantation, Anemia
Correcting Anemia and Native Vitamin D Supplementation in Kidney Transplant Recipients
The purpose of this study is to evaluate the effect of anemia correction and vitamin D supplementation in kidney transplant recipients.
- Conditions
- Kidney Transplantation, Anemia, Vitamin D Deficiency, Renal Insufficiency, Chronic
- Trial name
- CANDLE-KIT (NCT01817699)
- Testing
- High Hb target, cholecalciferol
- Where
- Japan
- Volunteers
- 161 people
- Sponsor
- CANDLE-KIT Trial Study Group
Polyethylene Glycols, Children, Only
Polyethylene Glycol Safety in Children
The primary objective is to measure levels of selected PEG 3350 components and metabolites in the blood and urine of children who are already taking PEG 3350 compared to children who are not taking PEG 3350.
- Trial name
- NCT05424757
- Testing
- PEG 3350
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Colonic Polyps
Panchromoendoscopy Using Oral Indigo Carmine Mixed With Polyethylene Glycol Prep
This study first is designed to see what dose of indigo carmine ingested orally mixed with the standard colonoscopy prep is needed to provide adequate staining of the right colon.
- Trial name
- NCT01901510
- Testing
- Chromoendoscopy (Indigo Carmine), Control
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Mayo Clinic