Clinical trials: Polyethylene Glycols
Bowel Preparation, Colonoscopy
Bowel Preparation for Colonoscopy in the Elderly
The success of colonoscopy is closely related to the quality of colonic preparation. However, data regarding colonoscopy preparations in the elderly (65 years older) are scarce.
- Trial name
- NCT02290093
- Testing
- Standard full-volume PEG, Split-dose full-volume PEG, Split-dose low-volume PEG
- Where
- 3 sites in South Korea
- Volunteers
- 230 people
- Sponsor
- Kyunghee University Medical Center
Colonoscopy, Hospitalized Patients
1L- vs. 4L-PEG for Bowel Preparation Among Inpatients.
Background and aims: Inpatients are at high risk for inadequate colon cleansing. Experts recommend 4L-polyethylene-glycol (PEG) solution because of its effectiveness and safety profile.
- Conditions
- Colonoscopy, Hospitalized Patients, Bowel Preparation
- Trial name
- NCT04310332
- Testing
- 1L-PEG, 4L-PEG
- Where
- 10 sites in Italy
- Volunteers
- 1,004 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Colonoscopy
The Efficacy Side Effects and the Tolerance of Polyethylene Glycol 3350 as a Bowel Prep in Children
Bowel preparation solutions containing Polyethylene Glycol is a commonly used preparation of the colon for colonoscopy in children.
- Trial name
- NCT01164410
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- The Cleveland Clinic
Constipation
Preference of Tegaserod vs. PEG 3350 in Patients With Constipation
To determine whether female patients have a preference for tegaserod of PEG 3350 relative to dosage form, convenience, ease of administration and taste
- Trial name
- NCT00171522
- Testing
- Tegaserod and Polyethylene Glycol 3350
- Where
- 14 sites in United States
- Volunteers
- 52 people
- Sponsor
- Novartis
Anemia
A Study of Methoxy Polyethylene Glycol-Epoetin Beta (Mircera) for the Treatment of Chronic Renal Anemia in Participants With Diabetic Nephropathy
This single arm, open label study will assess the efficacy, safety and tolerability of methoxy polyethylene glycol-epoetin beta for the treatment of chronic renal anemia in participants with chronic kidney disease (CKD) secondary…
- Trial name
- NCT01191983
- Testing
- Methoxy polyethylene glycol-epoetin beta [Mircera]
- Where
- 14 sites in India
- Volunteers
- 102 people
- Sponsor
- Hoffmann-La Roche
Type 2 Diabetes
A PK/PD Study of Polyethylene Glycol Loxenatide in Patients With Type 2 Diabetes
Polyethylene Glycol Loxenatide (PEX168) is a new human glucagon-like peptide 1 (GLP-1) analogue that created on the basis of the Exenatide and modified by polyethylene glycol (PEG).
- Trial name
- NCT01965509
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Slow Transit Constipation, Pharmacotherapy
Efficacy and Safety of Lubiprostone in the Treatment of Slow Transit Constipation
Lubiprostone has established efficacy and a favorable safety profile in chronic constipation and irritable bowel syndrome with constipation (IBS-C).
- Trial name
- STOPS 03 (NCT07277907)
- Testing
- Lubiprostone, Polyethylene glycol (PEG )
- Where
- 20 sites in China
- Volunteers
- 346 people
- Sponsor
- Third Military Medical University
Bowel Preparation Solution, Colonoscopy
Comparison of Bowel Preparation Using 2 Liter Polyethylene Glycol Regimen Plus Elobixibat Versus 4-Liter Polyethylene Glycol Regimen
Comparison of bowel preparation using 2 liter polyethylene glycol regimen plus elobixibat Versus 4-Liter polyethylene glycol regimen.
- Trial name
- NCT06436833
- Testing
- 2-Liter polyethylene glycol plus elobixibat, 4-Liter polyethylene glycol
- Where
- Thailand
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Peripheral Nerve Injuries
Evaluating the Safety and Efficacy of Polyethylene Glycol (PEG) Mediated Fusion (PEG Fusion)
The overall objective of this study is to determine the safety of PEG fusion when used with primary repair or reconstruction in patients with an acute upper extremity peripheral nerve injury.
- Trial name
- NCT04789044
- Testing
- NTX-001
- Where
- 7 sites in United States
- Volunteers
- 40 people
- Sponsor
- Major Extremity Trauma Research Consortium
HIV Infections
The Safety and Effectiveness of a Type of Interleukin-2 Plus Zidovudine Plus Thymosin in HIV-Positive Patients With and Without Symptoms of Infection
To determine the safety of thymosin alpha 1 given twice weekly in a regimen of daily oral zidovudine (AZT) and biweekly polyethylene glycolated interleukin-2 (PEG IL-2).
- Trial name
- NCT00001036
- Testing
- Thymalfasin, Interleukin-2, Polyethylene Glycolated, Zidovudine
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Fissure in Ano
Pediatrics Anal Fissures Treatment With Polyethylene Glycol
To evaluate whether effectively treating anal fissure-associated constipation using oral PEG alone can eliminate the inconvenience of add topical agent such as DTZ.
- Trial name
- NCT02419534
- Testing
- Polyethylene glycol, Polyethylene glycol with Diltiazem
- Where
- Saudi Arabia
- Volunteers
- 46 people
- Sponsor
- King Saud University
Bowel Disease
Plenvu 1 - Questionnaire Study Exploring Patients Preference in Bowel Preparation Timings for Morning Colonoscopy
Questionnaire study exploring patients preference in bowel preparation timings for morning colonoscopy.
- Trial name
- NCT04456790
- Where
- United Kingdom
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Portsmouth Hospitals NHS Trust
Anemia
A Study for Monthly Methoxy Polyethylene Glycol-Epoetin Beta Treatment in Patients With Chronic Renal Anaemia
This open-label single-arm study will evaluate the efficacy, safety and tolerability of methoxy polyethylene glycol epoetin beta on long-term maintenance of haemoglobin levels in patients with chronic renal anaemia.
- Trial name
- NCT01066000
- Testing
- methoxy polyethylene glycol-epoetin beta [Mircera]
- Where
- 12 sites in Indonesia
- Volunteers
- 33 people
- Sponsor
- Hoffmann-La Roche
Bowel Preparation, Colonoscopy
Low Volume PEG With Low Residue Test Meals Versus High Volume Split-dose PEG Bowel Preparation
Morning only low volume PEG with low reside meals may enhance patient tolerability and have similar bowel cleansing efficacy compared to standard method using high volume split-dose PEG with standard diet.
- Trial name
- LOWPEG (NCT01568814)
- Testing
- Low volume PEG, high volume PEG
- Where
- South Korea
- Volunteers
- 188 people
- Sponsor
- Inje University
Bowel Preparation
Comparison of Split-dose and Single-dose Bowel Preparation Regimens Using Polyethylene Glycol Electrolyte(PEG)
The goal of this quasi-experimental study was to compare the effect of single-dose and split-dose 3L compound polyethylene glycol electrolyte powder (PEG) regimen on the quality, comfort and tolerability of bowel preparation in…
- Trial name
- PEG (NCT06551883)
- Testing
- different bowel preparation regime, traditional bowel preparation regime
- Where
- China
- Volunteers
- 101 people
- Sponsor
- Tongji Hospital
Colonoscopy
Effectiveness of Gum Chewing on Polyethylene Glycol Related Intake Adherence, GI Side Effects and Bowel Preparation
Problem statement An Experimental Study to assess the effectiveness of Gum Chewing on Polyethylene Glycol (PEG) Related Intake Adherence, GI Side Effects and Bowel Preparation among Patients Undergoing Colonoscopy at ILBS, New…
- Trial name
- NCT05328219
- Testing
- Chewing gums with PEG solution, Standard of care
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Colonoscopy
Testing How Well Magnesium Citrate Capsules Work as Preparation for a Colonoscopy
This study compares a colonoscopy preparation composed of magnesium citrate capsules to a preparation of polyethylene glycol solution.
- Trial name
- NCT03247595
- Testing
- Magnesium Citrate Capsules, Polyethylene Glycol 3350, Dulcolax Tablets
- Where
- 2 sites in United States
- Volunteers
- 62 people
- Sponsor
- LifeBridge Health
Colonoscopy
Morning-Only 4 L PEG vs Split Dose Prep for Afternoon Colonoscopies, Endoscopist-Blinded Prospective Study
Comparison of quality of preparation of colonoscopy in patients taking same day 4L preparation vs. 4 L split dose preparation in patients scheduled for an afternoon colonoscopy procedure.
- Trial name
- NCT02643316
- Testing
- Same day 4 L preparation (Polyethylene Glycol), Split dose 4 L preparation (Polyethylene Glycol)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Type 2 Diabetes Mellitus, Colonoscopy
Abnormal Blood Sugar Tests in Diabetic Patients During Colonoscopy Preparation
Type 2 diabetes is rapidly increasing globally and has been associated with an increased risk of colorectal cancer. Therefore, the numbers of diabetic patients who will undergo colonoscopic screening are expected to grow…
- Trial name
- NCT03109951
- Testing
- Colonoscopy preparation using polyethylene glycol
- Where
- South Korea
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Catholic Kwandong University
Colorectal Disorders
The Use of Osmotic Laxatives Versus Macrogol for Bowel Preparation in Patients Undergoing Colonoscopy
The gold standard of colorectal examination is colonoscopy. One of the main purposes of colonoscopy is detecting bowel neoplasms. Right now there are several methods the bowel preparation for the colonoscopy.
- Trial name
- CLEAN (NCT04225793)
- Testing
- Eziklen®, MoviPrep
- Where
- Russia
- Volunteers
- 98 people
- Sponsor
- Russian Society of Colorectal Surgeons