Clinical trials: Polymorphism
Mitral Valve Prolapse
Mitral Valve Prolapse (MVP) - France Study
This prospective nation-wide (France) study aims to search for susceptibility genes in MVP using a genome wide analysis and comparing results obtained in 1000 patients with MVP and 1000 non-MVP subjects.
- Trial name
- MVP-France (NCT00799565)
- Testing
- catch of blood
- Where
- 26 sites in France
- Volunteers
- 1,179 people, healthy volunteers welcome
- Sponsor
- French Cardiology Society
Weight Management, Diet Conditions
A to Z Study Follow-up: Collection of DNA Data From Buccal Swabs
The goal of this study is to determine the association between genotypes and diet. The weight and weight loss data are already available from the previously completed study called: A to Z Study - Benefits and Risks of Alternative…
- Conditions
- Weight Management, Diet Conditions, Dietary Recommendations, Overweight Management
- Trial name
- NCT00866151
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Interleukin Genetics, Inc.
Healthy, Omega 3
Observing Metabolism of EPA With Consideration of Genetics And Sex
The goal of this clinical study is to learn how fast EPA is converted to other molecules, including DHA, with consideration of biological sex and genetics in healthy humans.
- Conditions
- Healthy, Omega 3, Metabolism, Lipids
- Trial name
- OMEGA (NCT06975241)
- Testing
- EPA 2.4g/day
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Abiraterone Acetate, Gene Polymorphism
Effects of Metabolic Enzymes and Transporter Gene Polymorphisms on the Pharmacokinetics and Metabolism of Oral Abiraterone Acetate in Healthy Chinese Adults
1. To explore the relationship between the changes of plasma concentration of abiraterone acetate after taken orally on fasting or postprandial and gene polymorphism. 2.
- Conditions
- Abiraterone Acetate, Gene Polymorphism, Pharmacokinetic, Metabolic Analysis
- Trial name
- NCT04735913
- Testing
- Abiraterone acetate tablets
- Where
- China
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Zhongnan Hospital
Polymorphism, Genetic, Bacterial Infections
The Association of Gene Polymorphisms With Invasive Bacterial Infections in Neonates and Young Infants
Invasive bacterial infections (IBIs) are globally significant, with high mortality rates, particularly within the critical 0-3 month age bracket.
- Conditions
- Polymorphism, Genetic, Bacterial Infections, Infant
- Trial name
- NCT06985160
- Testing
- Specific single nucleotide polymorphisms
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ege University
Healthy
Impact of Genetic Polymorphism on Drug-Drug Interactions Involving CYP2D6
CYP2D6 is characterized by a huge variability in the general population, mainly because of genetic polymorphism and drug-drug interactions (DDIs). CYP2D6 genotype is known to have an impact on the extent of DDIs.
- Trial name
- NCT03054220
- Testing
- Dextromethorphan 5 MG, Tramadol 10 mg, Duloxetine 60mg
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Jules Desmeules