Clinical trials: Polyp, Colonic
Colon Polyp, Colon Neoplasm
Effect of Enhanced Interactive Text Messages and Phone Instruction on the Quality of Bowel Preparation for Colonoscopy.
Efficacy Evaluation of Enhanced Bowel Preparation Instructions in Elective Colonoscopy.
- Trial name
- NCT04898426
- Testing
- Enhanced bowel preparation instruction
- Where
- Australia
- Volunteers
- 500 people
- Sponsor
- Griffith Base Hospital
Colorectal Polyp, Colorectal Cancer
Assessment of the Blink (First) Impression Regarding the Presence of Cancer Within Colorectal Polyps
Colorectal cancer (CRC) is a leading cause of death in the Western world. It can be effectively prevented by removal of pre-malignant polyps during colonoscopy.
- Conditions
- Colorectal Polyp, Colorectal Cancer, Colono
- Trial name
- NCT05699954
- Testing
- Presence of Blink impression features for cancer in colorectal polyps
- Where
- Belgium
- Volunteers
- 191 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Colorectal Adenoma, Colorectal Polyp
EndoRings Colonoscopy vs Standard Colonoscopy
The study aims to compare the results between a standard colonoscopy to a colonoscopy with an attachment on the distal end of the colonoscope.
- Conditions
- Colorectal Adenoma, Colorectal Polyp, Colon Cancer
- Trial name
- NCT03418662
- Testing
- EndoRings device
- Where
- United States
- Volunteers
- 592 people, healthy volunteers welcome
- Sponsor
- Indiana University
Colon Polyps
Colorectal Polyp Discrimination Using High-Definition Narrow Band Imaging
The investigators seek to compare the accuracy of the existing colonoscope model to determine the magnitude of the improvement the investigators can expect in polyp discrimination as neoplastic or non-neoplastic.
- Trial name
- NCT01354873
- Where
- United States
- Volunteers
- 556 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Colorectal Neoplasms, Colorectal Cancer
Bile Acids and Microbiome in Early Colorectal Carcinogenesis
Currently colorectal cancer pathogenesis is mainly explained by the adenoma-carcinoma sequence theory that was proposed more than half a century ago.
- Conditions
- Colorectal Neoplasms, Colorectal Cancer, Colorectal Polyp, Microbiome
- Trial name
- NCT06502704
- Where
- Lithuania
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vilnius University
Familial Adenomatous Polyposis
Safety Study for the Use of Rapamycin in Children With Familial Adenomatous Polyposis
The hypothesize of this research is that rapamycin is effective and well-tolerated in teenagers with familial adenomatous polyposis (FAP).
- Trial name
- RAPA-4-PAF (NCT06308445)
- Testing
- Rapamycin
- Where
- 4 sites in France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Toulouse
Colonoscopy, Colonic Polyps
Study of AQUAVAN® Injection (AQUAVAN; Fospropofol Disodium) for Sedation During Colonoscopy
Very often, patients receive sedative medication before a diagnostic, therapeutic, or surgical procedure to help them relax, keep them calm, and to relieve them from pain. This is called procedural sedation.
- Trial name
- NCT00125424
- Testing
- AQUAVAN® (fospropofol disodium) Injection, Midazolam HCl
- Where
- 20 sites in United States
- Volunteers
- 125 people
- Sponsor
- Eisai Inc.
Colon Polyps, Adenomatous Polyps
Prospective Study for Evaluating Colon Polyp Histology With in Vivo Probe Based Confocal Laser Endomicroscopy
Chromoendoscopy (that involves spraying of dyes over the colonic mucosa) combined with magnification has been utilized for polyp histology identification.
- Conditions
- Colon Polyps, Adenomatous Polyps, Colon Cancer
- Trial name
- NCT01214031
- Testing
- Confocal laser endomicroscopy (CLE)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Midwest Biomedical Research
Multiple Polyps Right Colon, Large Polyp Right Colon
Megachannel Device for Advanced Colonoscopy
Megachannel is a newly developed colonic access system allowing rapid and multiple passes of the colonoscope to the right colon.
- Conditions
- Multiple Polyps Right Colon, Large Polyp Right Colon, Suspected Polyp Right Colon
- Trial name
- NCT00987896
- Testing
- Colonoscopy with Megachannel™ device loaded
- Where
- Austria
- Volunteers
- 41 people
- Sponsor
- Medical University of Vienna
Colonic Polyps
Evaluation of Computer-assisted, Non-cathartic CT Colonography
The purpose of this study is to evaluate the performance of a non-cathartic, computer-assisted form of CT Colonography (Virtual Colonoscopy) for detection of pre-cancerous colon polyps in a group of asymptomatic screening…
- Trial name
- ncCTC (NCT01200303)
- Testing
- non-cathartic CTC
- Where
- 3 sites in United States
- Volunteers
- 605 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Polyp of Large Intestine, Colonic Polyps
Efficacy and Safety of a New Polypectomy Snare for Cold-polypectomy for Small Colorectal Polyps
Colorectal cancer is a major cause of morbidity and mortality in Western countries. Scientific studies have shown that endoscopic polypectomy is efficacious in preventing CRC incidence and mortality.
- Conditions
- Polyp of Large Intestine, Colonic Polyps, Colon Nos Polypectomy Tubular Adenoma, Complications
- Trial name
- NCT02245854
- Testing
- Exacto™
- Where
- 3 sites in Italy
- Volunteers
- 250 people
- Sponsor
- Istituto Clinico Humanitas
Colorectal Polyps
Accuracy and Sustainability of SCALE-EYE Evaluation for Measuring Reliable Polyp Size
A multicenter, randomized, parallel group, endoscopist blinded study to assess the diagnostic performance and sustainability of SCALE-EYE in a screening and surveillance colonoscopy population.
- Trial name
- ASSEMBLE (NCT07005453)
- Testing
- SCALE-EYE (1), SCALE-EYE (2)
- Where
- 3 sites in Netherlands
- Volunteers
- 241 people
- Sponsor
- Erasmus Medical Center
FAP, Familial Adenomatous Polyposis
Investigation of β-hydroxybutyrate Supplementation as Chemoprevention in Familial Adenomatous Polyposis
The aim of this study is to evaluate the potential of BHB supplementation as a novel strategy to impede the development and progression of intestinal adenomas in individuals with FAP, thus potentially reducing the need for…
- Trial name
- BHB-FAP (NCT06578637)
- Testing
- R-1,3-Butanediol (10G-A), R-1,3-Butanediol (20G-A), R-1,3-Butanediol (30G-A)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Artificial Intelligence, Enteroscope
A Clinical Trial of the Effectiveness and Safety of Software Assisting Diagnose the Intestinal Polyp Digestive Endoscopy by Analysis of Colonoscopy Medical Images From Electronic Digestive Endoscopy Equipment
A clinical trial of the effectiveness and safety of intestinal polyp digestive endoscopy-assisted diagnosis software used in the analysis of colonoscopy medical images generated by electronic digestive endoscopy equipment.
- Conditions
- Artificial Intelligence, Enteroscope, Intestinal Polyposis, Adenomatous
- Trial name
- NCT05687318
- Testing
- DeFrame
- Where
- China
- Volunteers
- 337 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Acute Leukemia, Adenomatous Polyposis
Familial Investigations of Childhood Cancer Predisposition
NOTE: This is a research study and is not meant to be a substitute for clinical genetic testing. Families may never receive results from the study or may receive results many years from the time they enroll.
- Conditions
- Acute Leukemia, Adenomatous Polyposis, Adrenocortical Carcinoma, AML
- Trial name
- SJFAMILY (NCT03050268)
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- St. Jude Children's Research Hospital
Colonic Polyps
Artificial Intelligence in the Characterization of Colorectal Polyps
Current guidelines recommend resection and histopathological analyses of all colorectal polyps. Real-time optical diagnosis can obviate non-neoplastic polyp resection ("diagnose-and-leave-behind") and histopathological analyses…
- Trial name
- NCT04749277
- Testing
- CAD EYE® (Fujifilm, Europe, Gesellschaft mit beschränkter Haftung, Dusseldorf, Germany)
- Where
- Portugal
- Volunteers
- 197 people
- Sponsor
- Unidade Local de Saúde de Coimbra, EPE
Colon Cancer
Cancer Control Following Polypectomy
This study evaluates strategies for the surveillance of post-polypectomy patients for the control of bladder cancer
- Trial name
- NCT00591279
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Neoplasms, Colorectal
Green Tea Extracts for the Prevention of Colorectal Adenomas and Colorectal Cancer
Experimental studies have shown the chemopreventive properties of green tea extract (GTE) on colorectal cancer. And colorectal adenomas are precursors to colorectal cancers.
- Trial name
- NCT02321969
- Testing
- GTE (green tea extract)
- Volunteers
- 176 people
- Sponsor
- Seoul National University Hospital
Colonic Adenoma, Colonic Polyp
Endocuff With or Without AI-assisted Colonoscopy
Colonoscopy is considered the gold standard for diagnosis of colonic polyps. However, it was reported that colonoscopy could still miss colonic polyps. Many attempts have been made to improve the detection rate of colonoscopy.
- Conditions
- Colonic Adenoma, Colonic Polyp, Colonic Cancer
- Trial name
- NCT05133544
- Testing
- Endocuff with AI, AI alone
- Where
- Hong Kong
- Volunteers
- 656 people
- Sponsor
- The University of Hong Kong
Adenomatous Polyposis Coli, Familial Adenomatous Polyposis
Cold Atmospheric Plasma for the Endoscopic Treatment of Duodenal Polyps in Patients With Familial Adenomatous Polyposis
The objective of this study is to investigate the feasibility for the treatment of precancerous peri-ampullary FAP polyps in the duodenum using low-thermal argonplasma.
- Conditions
- Adenomatous Polyposis Coli, Familial Adenomatous Polyposis, Duodenal Adenoma
- Trial name
- coldAPC (NCT06435533)
- Testing
- low energy argonplasma coagulation
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf