Clinical trials: Polyp, Colonic
Quality of Bowel Preparation for the Colon Capsule, Colon Capsule Completion Rates
Improving Bowel Preparation for the Colon Capsule
Colon capsule endoscopy is a technology that has been developed as a noninvasive method of examining the large bowel. The biggest limitation to its use has been finding a bowel preparation that will both clean the colon…
- Conditions
- Quality of Bowel Preparation for the Colon Capsule, Colon Capsule Completion Rates, Colon Capsule Polyp Detection
- Trial name
- NCT01655095
- Testing
- PEG, Prucalopride, Picosalax
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Queen's University
Colon Adenoma, Colonic Polyp
Linked Color Imaging (LCI) for Colorectal Adenoma Detection
Linked color imaging (LCI) is newly developed image-enhancing endoscopy technology that differentiates the red color spectrum more effectively than white light imaging thanks to its optimal pre-process composition of light…
- Trial name
- NCT03690297
- Testing
- Linked Color Imaging
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- Valduce Hospital
Familial Adenomatous Polyposis (FAP)
Efficacy of Vitamin B1 in Familial Adenomatous Polyposis Patients.
This study aimed to investigate the efficacy of vitamin B1 in patients with familial adenomatous polyposis, and to determine the inhibitory effect of vitamin B1 on the size and number of colorectal adenomas by administering oral…
- Trial name
- VitB1; FAP (NCT06649825)
- Testing
- Vitamin B1
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Shanghai Zhongshan Hospital
Colon Cancer, Colon Sessile Serrated Adenoma/Polyp
Narrow Band Imaging Versus White Light for Colonoscopy Serrate Lesions Detection
Colorectal cancer (CRC) is a leading cause of cancer death and its' incidence is rising in most European countries. Colonoscopy has been shown to reduce CRC incidence, however its effectiveness depends on the sensitivity to…
- Trial name
- NCT02876133
- Testing
- narrow band imaging withdrawal, white light withdrawal
- Where
- 3 sites in Portugal
- Volunteers
- 987 people, healthy volunteers welcome
- Sponsor
- Hospital Beatriz Ângelo
Colorectal Neoplasm
Prevalence and Spectrum of Cancer Susceptibility Among Patients with Advanced Colorectal Polyps
The study is being conducted to determine the prevalence and risk factors for germline cancer susceptibility genetic mutations among patients with advanced colorectal polyps.
- Trial name
- NCT04160832
- Testing
- Multi-Cancer Cancer Panel
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Colorado, Denver
Colonic Polyp, Colonic Neoplasms
Combined Forward and Retroflexion Withdrawal in the Detection of Polyps and Adenoma During Colonoscopy
Colonoscopy is the standard of care for the detection of colorectal polyps and adenoma, and colorectal cancer detection. Despite a meticulous evaluation of the colonic mucosa during colonoscopy, a substantial number of colorectal…
- Conditions
- Colonic Polyp, Colonic Neoplasms, Colonic Adenoma
- Trial name
- NCT03901651
- Testing
- Colonoscopy with Retroview scope combing forward and retroflexed withdrawal technique, Colonoscopy with standard colonoscope and forward withdrawal technique
- Where
- Ecuador
- Volunteers
- 203 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Polyps
Evaluation of an Endoscopic Suturing System for Tissue Apposition in Colonic Polypectomy
The purpose of this study is to show that the surgical site in the bowel wall can be sewn closed in the colon or intestine, with a new sewing device after removal of a benign polyp according to standard of care.
- Trial name
- NCT00553436
- Testing
- Tissue Apposition System (TAS) Device
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Ethicon Endo-Surgery
Colorectal Cancer, Adenoma
G-Eye Advanced Colonoscopy For Increased Polyp Detection Rate-randomized Tandem Study With Different Endoscopist
The purpose of this study is to compare the adenoma detection rate of G-EYE™ high definition colonoscopy with that of standard high definition colonoscopy.
- Trial name
- NCT02066064
- Testing
- Standard Colonoscopy, G-EYE(TM) Colonoscopy
- Where
- Germany
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Smart Medical Systems Ltd.
Colorectal Neoplasms, Colonic Polyps
Clinical Validity Verification on Diagnostic Assistance for Presence and Severity of Colorectal Cancer and Polyps Using Artificial Intelligence-based Medical Device Software Endoscopic Imaging Assistance
This completed retrospective study evaluated the clinical performance of ENAD-CADx-01, an artificial intelligence-based medical device software intended to assist healthcare professionals in characterizing colorectal lesions in…
- Conditions
- Colorectal Neoplasms, Colonic Polyps, Hyperplastic Polyps, Sessile Serrated Lesions
- Trial name
- NCT07744607
- Where
- South Korea
- Volunteers
- 1,114 people
- Sponsor
- Ainex Corporation
Colorectal Cancer, Colorectal Adenomas
Water-aided Colonoscopy vs Air Insufflation Colonoscopy in Colorectal Cancer Screening
The degree of protection afforded by colonoscopy against proximal colorectal cancer (CRC) appears to be related to the quality of the procedure, and the incomplete removal of lesions has been shown to increase the subsequent risk…
- Conditions
- Colorectal Cancer, Colorectal Adenomas, Colorectal Polyps, Pain
- Trial name
- NCT02041507
- Testing
- Air insufflation method., Water Immersion method., Water Exchange method.
- Where
- 4 sites in United States, Czechia and 1 more
- Volunteers
- 1,224 people
- Sponsor
- Presidio Ospedaliero Santa Barbara
Colonic Polyp, Colonic Adenoma
Detection Of Colonic Polyps In India: Diagnostic Colonoscopy
Colorectal carcinoma (CRC) is the third most common cancer in male and female worldwide. In India, it is the fourth most common cause of cancer in males and third most common cancer in female.
- Conditions
- Colonic Polyp, Colonic Adenoma, Colonic Neoplasms
- Trial name
- DoCPI (NCT04512729)
- Testing
- Colonoscopy
- Where
- India
- Volunteers
- 4,000 people
- Sponsor
- Asian Institute of Gastroenterology, India
Colorectal Cancer, Adenoma Colon
Liquid Biopsy and Machine Learning for Early Colorectal Cancer, Adenomas, Lynch Cancers, and Residual Disease Detection
This is an multicenter study that will test the diagnostic accuracy of a blood test (i.e., a liquid biopsy) for the diagnosis of colorectal cancer (CRC), advanced adenomas (AAs), as well as Lynch-syndrome associated cancers.
- Conditions
- Colorectal Cancer, Adenoma Colon, Adenoma Colon Polyp, Colon Adenoma
- Trial name
- BEACON (NCT07450612)
- Testing
- BEACON
- Where
- 4 sites in Italy
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- San Raffaele University
Colonic Polyp
Characterization of Colorectal Neoplasia
This is a post-marketing, single-arm, prospective study investigating the use of GI Genius CADx device in the real-time characterization of colorectal polyps (i.e. prediction of their histology during the colonoscopy).
- Trial name
- CHANGE (NCT04884581)
- Testing
- GI Genius CADx device
- Where
- Italy
- Volunteers
- 165 people
- Sponsor
- Nuovo Regina Margherita Hospital
Familial Adenomatous Polyposis
Colorectal Adenoma Canceration in FAP
The current internationally accepted treatment method for familial adenomatous polyposis is prophylactic total colorectal resection combined with endoscopic follow-up.
- Trial name
- NCT04531930
- Testing
- surgery, enhanced colonoscopy, self choosed methods
- Where
- China
- Volunteers
- 124 people
- Sponsor
- Changhai Hospital
Colorectal Cancer
Clinical Validation of Polydeep: an Artificial Intelligence-based Computer-aided Polyp Detection (CADe) and Characterization (CADx) System
This study is a clinical validation of Polydeep, a computer-aided polyp detection (CADe) and characterization (CADx) system. Polydeep Advance 1 is an unicentric prospective diagnostic tests trial with a paired study design.
- Trial name
- NCT05514301
- Testing
- Sensitivity of Polydeep vs high experienced endoscopists for colorectal polyp detection
- Where
- Spain
- Volunteers
- 205 people
- Sponsor
- Fundacin Biomedica Galicia Sur
Colon Polyp
Microbiome Test for the Detection of Colorectal Polyps
The main goal of this trial is to validate a new method for colorectal polyp screening based on stool microbiome signatures. 600 Individuals who are scheduled / planned to undergo a colonoscopy will be recruited for this study…
- Trial name
- NCT05060757
- Testing
- biotax
- Where
- 2 sites in Israel
- Volunteers
- 600 people
- Sponsor
- Biotax Labs LTD
Polyp of Colon
The Non-Optical Resect and Discard Study (NORD)
Eliminating the need for conventional histopathological assessment of diminutive colon polyps - The Non-Optical Resect and Discard (NORD) study
- Trial name
- NORD (NCT04032912)
- Testing
- iScan
- Where
- Canada
- Volunteers
- 1,200 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Duodenal Adenomas, Familial Adenomatous Polyposis
CryoBalloon Ablation for Treatment of Duodenal Adenomas
This multicenter prospective non-randomized interventional study (clinical trial) that will assess the safety and efficacy of cryoballoon ablation treatment using the C2 Cryoballoon device (Pentax Medical Corporation) as an…
- Trial name
- C2D2 (NCT03847636)
- Testing
- CryoBalloon ablation
- Where
- 4 sites in United States
- Volunteers
- 33 people
- Sponsor
- Johns Hopkins University
Colorectal Cancer Screening, Colon Adenomatous Polyp
Ambient Lighting During Colonoscopy and Its Effect on Adenoma Detection Rate and Eye Fatigue
A retrospective and prospective study to determine if the use of ambient lighting during screening colonoscopy is well tolerated and if ambient lighting will help physicians maintain adenoma detection rates while decreasing…
- Trial name
- NCT04441242
- Testing
- Ambient lighting, Low lighting
- Where
- United States
- Volunteers
- 1,109 people
- Sponsor
- Wake Forest University Health Sciences
Familial Adenomatous Polyposis
Visualization of the Papilla Through Use of the NuView Device in Patients With FAP
The goal of this observational study is to test the NuView device in participants with familial adenomatous polyposis (FAP). The main question it aims to answer is: can the papilla be visualized using a forward-facing endoscope…
- Trial name
- NuView (NCT05657145)
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Vanderbilt University Medical Center