Clinical trials: Polyp Endometrium
Infertility, Abnormal Uterine Bleeding (AUB)
Evaluation of the Uterine Cavity After Operative Hysteroscopy
This study will focus on evaluation of the uterine cavity after operative hysteroscopy using three dimensional transvaginal ultrasonography and office hysteroscopy to detect and residual or recurrent abnormalities or intrauterine…
- Conditions
- Infertility, Abnormal Uterine Bleeding (AUB), Intrauterine Adhesion, Submucous Leiomyoma of Uterus
- Trial name
- NCT06924437
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Endometrial Polyp
The Effect of Levonorgestrel Intrauterine System in Preventing Endometrial Polyps Recurrence
The goal of this clinical trial is to determine whether the LNG-IUS is more effective to that of expectant in preventing endometrial polyp recurrence after hysteroscopic polypectomy.
- Trial name
- NCT06620939
- Testing
- Levonorgestrel Intrauterine System (LNG-IUS)
- Volunteers
- 558 people
- Sponsor
- Zhang Jian
Fibroid Uterus, Polyp Uterus
Comparison of Operative Hysteroscopy Performed in the Operating Room Versus Outpatient Settings
This is an observational prospective monocentric study which aims to compare operative hysteroscopies performed in the operating room under general or loco-regional anesthesia and those performed outside the operating room…
- Conditions
- Fibroid Uterus, Polyp Uterus, Retained Products of Conception
- Trial name
- NCT07146659
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Endometrial Polyp, Endometrial Diseases
The Use of Ethinylestradiol/Dienogest in Random Start Rapid Endometrial Preparation
The presence of a thin endometrium plays an important role in enabling the best conditions for hysteroscopic surgery. Recently, for this purpose, many studies have evaluated the effect of preoperative administration of a variety…
- Trial name
- NCT06316206
- Testing
- Ethinylestradiol/Dienogest 0.03mg/2mg
- Where
- 2 sites in Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Abnormal Uterine Bleeding, Postmenopausal Bleeding
Use of Nitrous Oxide During Office Hysteroscopy
The goal of this clinical trial is to assess the use of inhaled nitrous oxide during office hysteroscopy. The main questions it aims to answer are: Does it reduce pain during the procedure? Does it increase the success rate? Does…
- Conditions
- Abnormal Uterine Bleeding, Postmenopausal Bleeding, Endometrial Polyps, Retained Products of Conception
- Trial name
- NCT07074795
- Testing
- Inhalation of Nitrous Oxide (N₂O) during Office Operative Hysteroscopy, inhalation of ambient air during office hysteroscopy
- Where
- Israel
- Volunteers
- 400 people
- Sponsor
- Maaynei Hayesha Medical Center
Endometrial Polyp
Hand Driven Versus Motor Driven Hysteroscopic Tissue Removal System for Polypectomy: Long-term Results
In this study, a comparison is made between two types of polyp resection methods (hand driven and motor driven morcellation). More specifically, the effects of the resection on symptoms such as abnormal uterine bleeding, and on…
- Trial name
- NCT05337605
- Where
- Netherlands
- Volunteers
- 87 people
- Sponsor
- University Hospital, Ghent
Endometrial Polyp, Endometrial Diseases
The Use of Drospirenone/Estetrol in Random Start Rapid Endometrial Preparation
The presence of a thin endometrium plays an important role in enabling the best conditions for hysteroscopic surgery. Recently, for this purpose, many studies have evaluated the effect of preoperative administration of a variety…
- Trial name
- NCT06316180
- Testing
- drospirenone/estetrol 3mg/14.2mg
- Where
- 2 sites in Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Uterine Polyp, Uterine Bleeding
Pharmacological Preparation of the Cervix for Hysteroscopy
Pain accompanying office hysteroscopy is the most common reason for its discontinuation. Urogenital atrophy may cause technical difficulties in passage through the cervical canal, further increasing the pain.
- Conditions
- Uterine Polyp, Uterine Bleeding, Endometrium; Senility
- Trial name
- NCT05783479
- Testing
- estradiol, Hyaluronic acid
- Where
- Poland
- Volunteers
- 96 people
- Sponsor
- Jagiellonian University
Abnormal Uterine Bleeding
Studies on the H Pipelle, a New Device for Endometrial Sampling at Hysteroscopy
The investigators have developed a novel instrument for taking endometrial biopsies at no touch (vaginoscopic) hysterectomy which avoids the need to instrument the vagina with speculums and tenaculums, and also avoids the…
- Trial name
- NCT00755651
- Testing
- Endometrial biopsy
- Where
- United Kingdom
- Volunteers
- 180 people
- Sponsor
- Royal Free Hampstead NHS Trust
Large Intrauterine Polyps, Smaller Type 0 and 1 Myomas
The Hysteroscopic Morcellator (HM).
Rationale: The hysteroscopic morcellator (HM) is a novel technique for removal of intrauterine polyps, myomas and placental tissue. It withholds some technical advantages over resectoscopy.
- Conditions
- Large Intrauterine Polyps, Smaller Type 0 and 1 Myomas, Residual Placental Tissue
- Trial name
- HM (NCT01537822)
- Testing
- Hysteroscopic morcellator, Resectoscope
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 253 people
- Sponsor
- University Hospital, Ghent
Endometrial Polyps
Endometrial Polypectomy Performed With Bipolar Electrode Versapoint vs Microscissors or Graspers
Hysteroscopy today is considered the gold standard for the diagnosis and treatment of endometrial polyps. Several hysteroscopic systems to resect endometrial polyps are currently available.
- Trial name
- NCT02590666
- Testing
- Bipolar Polypectomy, Mechanical Polypectomy, Bipolar electrode
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Transcervical Resection of Endometrium, Transcervical Resection of Fibroids
Comparing Two Types of Sedation to Gynaecological Patients
The primary endpoint is to investigate the difference in pain between patients who receive deep sedation with spontaneous breathing versus patients who receive general anesthesia.
- Conditions
- Transcervical Resection of Endometrium, Transcervical Resection of Fibroids, Transcervical Resection of Polyp
- Trial name
- NCT01412632
- Testing
- Remifentanil, propofol and citanest
- Where
- Denmark
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Myoma;Uterus, Polyp Uterus
Paracervical Block Versus Transcervical Block in Outpatient Procedural Hysteroscopy
Hysteroscopy is a minimally invasive, diagnostic and therapeutic gynecological surgical technique and the gold standard in the study of the uterine cavity.
- Trial name
- NCT05967936
- Testing
- Bupivacaine Injection
- Where
- Canada
- Volunteers
- 242 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Uterine Leiomyomas, Endometrial Polyps
Symphion® System In-Office Study
The purpose of this study is to determine the safety and feasibility of using the Symphion system in an office setting.
- Trial name
- NCT02520414
- Testing
- Symphion® Bipolar Hysteroscopic Tissue Resection System
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Minerva Surgical, Inc.
Retained Products of Conception, Hysteroscopy
Predictors of Successful Office Operative Hysteroscopy Using a Mini-Resectoscope
The goal of this observational study is to identify predictors of successful removal of benign intrauterine pathology using a mini-resectoscope during office operative hysteroscopy without anesthesia in adult women with suspected…
- Conditions
- Retained Products of Conception, Hysteroscopy, Endometrial Polyp Benign, Endometrial Polyp
- Trial name
- NCT07875985
- Testing
- Office Operative Hysteroscopy Using the Karl Storz Mini-Resectoscope Without Anesthesia
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Shaare Zedek Medical Center
Asherman Syndrome, Endometrial Polyp
Efficiency of INTERCOAT (Oxiplex/AP Gel) in Preventing Intrauterine Adhesion Formation in Hysteroscopic Surgery
The study purpose is to examine the influence of INTERCOAT in prevention of intra-uterine adhesions formation after any hysteroscopic surgery.
- Conditions
- Asherman Syndrome, Endometrial Polyp, Uterine Myoma
- Trial name
- NCT01637974
- Testing
- INTERCOAT administration
- Where
- Israel
- Volunteers
- 130 people
- Sponsor
- Carmel Medical Center
Endometrial Polyps, Retained Products of Conception
Impact of Different Saline Pressures During Hysteroscopy on Visibility, Feasibility and Patients' Discomfort
Hysteroscopy is a minimally invasive diagnostic and therapeutic procedure for various intrauterine conditions. It is performed with an optic device while entering liquid media to the uterus to allow visualization.
- Conditions
- Endometrial Polyps, Retained Products of Conception, Lysis of Intrauterine Adhesions, Removal of Retained Intrauterine Device
- Trial name
- NCT06620978
- Testing
- Low pressure: Operative hysteroscopy without anesthesia with normal Saline medium in low pressure.., High pressure: Operative hysteroscopy without anesthesia with normal Saline medium in High pressure.
- Volunteers
- 100 people
- Sponsor
- Assaf-Harofeh Medical Center
Polyps Uterus
Bipolar 15 Charrières Office Resectoscope : Polypectomy Without Anesthesia
This study aimed to the feasibility of polypectomy without anesthesia using a 15 Ch. resectoscope in women with uterine polyps.
- Trial name
- HSC (NCT04331652)
- Testing
- Polypectomy without anesthesia or analgo-sedation
- Where
- France
- Volunteers
- 13 people
- Sponsor
- Hopital Foch
Infertility, Polyp Uterus
HYALOBARRIER® GEL ENDO Versus no HYALOBARRIER® GEL ENDO Following Operative Hysteroscopy for Improving Reproductive Outcome in Women With Intrauterine Pathology Wishing to Become Pregnant
To compare the costs and effects of HYALOBARRIER® GEL ENDO versus no HYALOBARRIER® GEL ENDO for increasing the chance of conception leading to live birth measured at 30 weeks after randomization in women wishing to become…
- Conditions
- Infertility, Polyp Uterus, Myoma;Uterus, Adhesion
- Trial name
- AGNOHSTIC (NCT03880435)
- Testing
- Hyalobarrier® gel endo
- Where
- Belgium
- Volunteers
- 419 people
- Sponsor
- University Hospital, Ghent
Endometrial Polyps
Morcellator Versus Resectoscope in the Treatment of Uterine Polyps by Hysteroscopy
Intrauterine pathologies are currently treated by hysteroscopic resection. In this surgical procedure, the intrauterine pathology is resected by a transcervical approach in several fragments using a mono or bipolar cove after…
- Trial name
- RESMO (NCT02472197)
- Testing
- Hysteroscopic morcellation, Standard hysteroscopic resection
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Strasbourg, France