Clinical trials: Polyp of Large Intestine
Colonic Polyp
Computer Assisted Measurement of Colorectal Polyps
Adenomas are polyps of the colorectum that have the potential to develop into colon cancer. However, some adenomas never become malignant tumors, or if so, progression from adenoma into cancer takes a long time.
- Trial name
- NCT02970760
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- Technical University of Munich
Colorectal Polyp, Colonoscopy
Synergistic Effect of G-Eye Balloon for Behind the Folds Visualization With CADe (Discovery System) on Adenoma Detection Rate.
Colonoscopy is the gold standard for colorectal screening. The diagnostic accuracy of colonoscopy highly depends on the quality of inspection of the colon during the procedure.
- Conditions
- Colorectal Polyp, Colonoscopy, Artificial Intelligence, Adenoma
- Trial name
- DiscoveryIII (NCT05220345)
- Testing
- colonoscopy assisted by both balloon-Behind The Folds visualizing and Computer assisted detection (CADe)
- Where
- Netherlands
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Colon Polyp, Adenoma
Six Versus Twelve Month Index Follow-up After Large Colon Polyp Resection
The study will compare the use of a 6-month follow-up vs a 12-month follow-up after the removal of a large non-pedunculated polyp 20-50mm in size and without high grade dysplasia.
- Conditions
- Colon Polyp, Adenoma, Serrated Polyp, Recurrence, Local Neoplasm
- Trial name
- STARLING (NCT07198945)
- Testing
- 6-month follow-up, 12-month follow-up
- Where
- 10 sites in United States, Canada and 1 more
- Volunteers
- 546 people
- Sponsor
- Indiana University
Polyp of Large Intestine
EFficacy of Prophylactic Clip Application in Decrease of Immediate Postpolypectomy Bleeding and Delayed Postpolypectomy Bleeding After Colonoscopic Removal for a Large Pedunculated Polyps
The aim of this study is to evaluate the efficacy of prophylactic clip application after colonoscopic removal for a large pedunculated polyp (> 1cm) in preventing immediate postpolypectomy bleeding (IPPB) and delayed…
- Trial name
- NCT01437631
- Testing
- prophylactic clip application
- Where
- South Korea
- Volunteers
- 137 people
- Sponsor
- Asan Medical Center
Colonic Polyps/Colonoscopy/Colorectal Neoplasms
Comparison of Cold and Hot Snare Resection for Colorectal Polyps Sized 10-19mm.
Patients who met the criteria for removal of 10-19mm colorectal polyps using cold snare or hot snare were included in the study, signed by endoscopic treatment written informed consent for surgery, patients with detailed tracking…
- Trial name
- NCT04451512
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Colorectal Neoplasms, Colorectal Polyp
MS Versus NICE for Colorectal Lesions
OBJECTIVE: Our study aimed to compare a recently-developed endoscopic classification with an established one for colorectal lesions in a randomised trial between 2013 and 2015.
- Trial name
- NCT02963207
- Testing
- Modified Sano's classification, NICE classification
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- Lyell McEwin Hospital
Colorectal Polyps
AI-Assisted Real-Time Endoscopic Characterization of Diminutive Colorectal Polyps in Non-Academic Hospitals
To validate the feasibility of promoting colorectal diminutive polyp "predict, resect, and discard" and "diagnose and leave" strategies for non-experts in general hospitals through CADx system.
- Trial name
- NCT07362524
- Testing
- AI-Assisted Real-time Endoscopic Diagnosis System
- Where
- 2 sites in China
- Volunteers
- 363 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Colorectal Polyp, Colorectal Cancer
Computer-aided Detection During Screening Colonoscopy
Nowadays, colonoscopy is considered the gold standard for the detection of lesions in the colorectal mucosa. However, around 25% of polyps may be missed during the conventional colonoscopy.
- Conditions
- Colorectal Polyp, Colorectal Cancer, Colorectal Adenoma
- Trial name
- NCT05734820
- Testing
- HD- colonoscopy, HD-colonoscopy assisted by AI
- Where
- Ecuador
- Volunteers
- 312 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Polyps, Adenoma Colon
Early DiAgnosis Real-Time Healthcare System for CANcer Trial
The purpose of the study is to assess whether the AI characterisation system of the CADDIE device improves the endoscopists accuracy in the optical diagnosis of diminutive colorectal polyps in the bowel during colonoscopy.
- Conditions
- Polyps, Adenoma Colon, Colorectal Polyp, Colon Polyp
- Trial name
- EARTHSCAN (NCT05064124)
- Testing
- CADDIE - Computer Aided Detection and Diagnosis for Intelligent Endoscopy
- Where
- United Kingdom
- Volunteers
- 420 people
- Sponsor
- University College, London
10-20 mm Pedunculated Colorectal Polyp
Investigation of Cold Snare Polypectomy for Removing 10-20 mm 0-Ip Colorectal Polyp
This is a multicenter, single-arm feasibility study conducted across multiple hospitals in Taiwan. The goal of this trial is to evaluate whether cold snare polypectomy is a feasible and safe method for removing 10-20 mm…
- Trial name
- NCT07114380
- Testing
- Cold snare polypectomy
- Where
- 5 sites in Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Adenomatous Polyps
A Comparison of the Resection Rate of Cold Snare Polypectomy for Large (10-15 mm) and Small (5-9 mm) Colorectal Polyps
Colorectal cancer remains the third most common cause of death from cancer worldwide. Colonoscopy allows removal of adenomatous polyps is the best colorectal cancer screening, according to the adenoma-carcinoma sequence.
- Trial name
- CSP (NCT03647176)
- Testing
- Cold snare polypectomy
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Yuqi He
Adenomatous Polyps
A Comparison of the Resection Rate for Hot and Cold Snare Polypectomy of Colorectal Polyps (10-15 Mm)
Colorectal cancer (CRC) has become the third most common malignant tumor and is the second leading cause of cancer related deaths worldwide. Adenomatous polyps of the colon are possible precursor lesions for CRC.
- Trial name
- COLDSNAP-2 (NCT04816292)
- Testing
- Active Comparator: Hot Snare Polypectomy, Experimental: Cold Snare Polypectomy
- Where
- Germany
- Volunteers
- 850 people
- Sponsor
- Technical University of Munich
Colorectal Cancer, Colorectal Polyp
Feasibility and Safety of MiWEndo-assisted Colonoscopy
The study involves the planned use of a new microwave-based device during colonoscopy procedures in a small group of patients to assess the preliminary safety of its use and lack of normal clinical practice modification.
- Conditions
- Colorectal Cancer, Colorectal Polyp, Colorectal Adenoma, Colorectal Neoplasms
- Trial name
- MiWEndo1 (NCT05477836)
- Testing
- MiWEndo-assisted colonoscopy
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- MiWEndo Solutions S.L.
Colorectal Neoplasms, Colorectal Polyp
A Prospective Investigation of the ColubrisMX ELS System
This study is a prospective, single-arm, open-label, multi-center, feasibility study to evaluate the safety and efficacy of the ColubrisMX ELS System in patients undergoing transanal endoluminal procedures, specifically…
- Conditions
- Colorectal Neoplasms, Colorectal Polyp, Colorectal Adenoma, Colorectal Adenomatous Polyp
- Trial name
- NCT04192565
- Testing
- ColubrisMX Endoluminal Surgical (ELS) System
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- ColubrisMX
Colorectal Polyps
Virtual Chromoendoscopy for Distal Polyps
To assess the accuracy of predicting histology with virtual chromoendoscopy for distal colorectal polyps according to the ASGE PIVI statement.
- Trial name
- NCT02217449
- Testing
- Prediction of histology
- Where
- Germany
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Colorectal Polyps
Discard:Characterisation of Colonic Polyps in Vivo
Prospective study of accuracy of colonic polyp characterisation in vivo using high resolution white light endoscopy, narrow band imaging and chromoendoscopy.
- Trial name
- DISCARD (NCT00888771)
- Where
- United Kingdom
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Colorectal Polyps
Virtual Colonoscopy (VC) for Primary Colorectal Screening
This study involves a primary VC screening for colorectal polyps. The research hypothesis is that VC screening, including surveillance of sub-cm polyps, is a safe and effective approach.
- Trial name
- NCT00204867
- Testing
- CTC surveillance
- Where
- United States
- Volunteers
- 272 people
- Sponsor
- University of Wisconsin, Madison
Colorectal Cancer
Real-Time Characterizations of Diminutive Colorectal Polyps Using Narrow Band Imaging
Colorectal cancer is the second leading cause of cancer related death in the United States. Colonoscopy is the most commonly performed screening procedure and diminutive polyps (<5mm) are the most commonly found polyps during…
- Trial name
- NCT02441998
- Testing
- Education intervention: Training in Narrow Band Imaging
- Volunteers
- 26 people
- Sponsor
- University of Michigan
Colorectal Polyp, Inflammation
Impact of Dietary Intervention on Inflammation and Microbiome Composition Post-Colonoscopy
This study aims to investigate the impact of various healthy diets, specifically a modified plant-based Mediterranean diet, on the gut microbiome and overall well-being post-colonoscopy.
- Conditions
- Colorectal Polyp, Inflammation, Dietary Intervention, Microbiota
- Trial name
- NCT06603519
- Testing
- Modified Plant-Based Mediterranean Diet
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Colorectal Polyps
Evalution of Optical Enhancement With Magnification for Polyop Histology
When a polyp is found, it woulf be recorded by a white-light and OE1 model with magnification for assessing and predicting its histology. After that, its really histology will be reported by an pathologist.
- Trial name
- NCT02929641
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shandong University