Clinical trials: Polypectomy
Colonic Polyps
Biopsy Forceps Versus Cold Snare for the Resection of Small Colonic Polyps
The purpose of this study is to evaluate and compare the incomplete resection rates for small colon polyps less than or equal to 6 mm in size using two conventional polypectomy tools, jumbo cold biopsy forceps and cold snare.
- Trial name
- NCT02239549
- Testing
- Jumbo cold forceps polypectomy, Cold snare polypectomy
- Where
- United States
- Volunteers
- 419 people, healthy volunteers welcome
- Sponsor
- San Diego Veterans Healthcare System
Surveillance Colonoscopy
Post-polypectomy Surveillance Interval In High-risk Subjects After Screening Colonoscopy
With many countries initiating population colorectal cancer (CRC) screening, including Hong Kong, more robust guidance for surveillance interval is required to maximize subject's benefit with optimal use of resources.
- Trial name
- NCT04034563
- Testing
- 1) Risk of metachronous advanced neoplasia at 3-year, beyond 3 years surveillance colonoscopy
- Where
- 2 sites in Hong Kong
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Endometrial Polyps
Comparative Study of Endometrial Polypectomy Performed With Bipolar Electrode Versapoint and Laser Diode. A Randomised Controlled Trial.
Hysteroscopy today is considered the gold standard for the diagnosis and treatment of endometrial polyps. In recent years we have used the bipolar energy for resection of polyps by hysteroscopy, becoming a routine clinical…
- Trial name
- NCT02126397
- Testing
- polyps resection with Laser Diode, polyps resection with bipolar electrode
- Where
- 2 sites in Spain
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Isabel Bejerano Blázquez
Colorectal Cancer, Colorectal Neoplasms
Early Detection of Advanced Adenomas and Colorectal Cancer
This study aims to develop a highly sensitive, specific, and cost-effective blood assay for early detection of colorectal adenomas and cancer, using advanced machine learning and state-of-the-art biological analyses.
- Conditions
- Colorectal Cancer, Colorectal Neoplasms, Colorectal Polyp, Colorectal Adenocarcinoma
- Trial name
- AACRC (NCT06342440)
- Testing
- DENEB
- Where
- 6 sites in United States, China and 3 more
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Colonic Polyp
Effect of Epinephrine on Post-polypectomy Pain
Epinephrine is widely used in endoscopic mucosal resection of large polyps to prevent post-polypectomy bleeding. No previous studies looked at increase in immediate post-polypectomy pain with the use of epinephrine.
- Trial name
- NCT04065451
- Testing
- Epinephrine
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Indiana University
Polyp of Large Intestine
Cold Snare Polypectomy Vs. Cold Forceps Polypectomy Using Narrow-band Imaging Endoscopy for Removal of Diminutive Colorectal Polyps
The purpose of this study is to compare cold snare polypectomy and cold forceps polypectomy using narrow-band imaging endoscopy for removal of diminutive colorectal polyps.
- Trial name
- NCT02201147
- Testing
- Cold biopsy polypectomy, Cold snare polypectomy
- Where
- South Korea
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Soonchunhyang University Hospital
Colorectal Polyp, Colorectal Cancer
Detection of Endoscopic Resection Scars and Delineation of Recurrence is Trainable
Colorectal cancer is prevented by colonoscopy and polypectomy. Failure to recognize the endoscopic resection scar after Endoscopic Mucosal Resection (EMR) risks unrecognized recurrent or residual adenoma (RRA), which may…
- Trial name
- SCAR (NCT06193356)
- Testing
- Learning tool
- Where
- Belgium
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Colorectal Polyps
Comparison of Two Types of Biopsy Forceps for Obtaining Cold Biopsy Polypectomy for Small Sessile Colorectal Polyps Less Than 6 mm in Diameter
The purpose of this study is to evaluate the efficacy of the new RJ4 compare with the standard RJ3 biopsy forceps for performing polypectomy for small colorectal polyps.
- Trial name
- NCT00855790
- Testing
- evaluate the effectiveness of the RJ4 biopsy forcep versus the RJ3 biopsy forcep
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Florida
Colonic Polyp
Impact of Augmented Reality in Polypectomy Skills Acquisition in Simulation-based Endoscopy Training
Simulation-based training (SBT) is a safe and effective strategy for improving skills development in gastrointestinal endoscopy.
- Trial name
- NCT03826069
- Testing
- Augmented reality-based curriculum, Conventional Simulation Curriculum
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Colonoscopy, Polypectomy
Comparison of Jumbo and Hot Biopsy Forceps
Cold forceps polypectomy and hot biopsy forceps electrocauterization (HBF) are still widely used methods for endoscopic resection of diminutive colorectal polyps (DCPs)(polyps smaller than 5 mm).
- Trial name
- NCT02188316
- Testing
- Jumbo forceps, Hot biopsy forceps
- Where
- Turkey (Türkiye)
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Camlıca Erdem Hospital
Colon Polyps
A Pilot Randomized Trial of Polypectomy Techniques for 4-6 mm Colonic Polyps
Complete polypectomy is one of the major factors for effectiveness of colonoscopy to prevent colon cancer. Given the prevalence of the 4-6 mm polyp, and the concern about interval cancers at polypectomy sites, there is a clear…
- Trial name
- NCT04666194
- Testing
- Cold forceps, Cold snare, Hot snare
- Where
- 3 sites in United States
- Volunteers
- 353 people, healthy volunteers welcome
- Sponsor
- Indiana University
Colorectal Polyp
Assessment of Endoscopic Tip Control Using a Novel Score Based on the Snare Tip Soft Coagulation of Polypectomy Margin Defects
Colorectal cancer is the third most common malignancy worldwide and the second leading cause of cancer related death with approximately 880 792 deaths every year (9,2% of the global yearly 9.6 million cancer deaths).
- Trial name
- NCT05660317
- Testing
- Tip control score
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Colorectal Cancer, Colorectal Polyp
Accuracy for Predicting Deep Submucosal Invasion
The main aim of this study is to determine whether the assessment of the invasive pattern based on NBI with dual focus/magnification or BLI with magnification ± chromoendoscopy (NBI+CE) for predicting deep invasion is…
- Trial name
- NBIBLI (NCT03748667)
- Testing
- White light endoscopy (WLE), NBI/BLI +/- chromoendoscopy (NBIBLI +/- CE)
- Where
- 14 sites in United States, Japan and 1 more
- Volunteers
- 426 people, healthy volunteers welcome
- Sponsor
- Althaia Xarxa Assistencial Universitària de Manresa
Endometrial Polyps
Endometrial Polypectomy Performed With Bipolar Electrode Versapoint vs Microscissors or Graspers
Hysteroscopy today is considered the gold standard for the diagnosis and treatment of endometrial polyps. Several hysteroscopic systems to resect endometrial polyps are currently available.
- Trial name
- NCT02590666
- Testing
- Bipolar Polypectomy, Mechanical Polypectomy, Bipolar electrode
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Colon Disease, Gastric Disease
Feasibility Trial to Evaluate the Ability of the SuMO Tissue Access and Resection System
This feasibility trial will evaluate the ability of the SuMO Tissue Access and Resection System (Apollo Endosurgery, Austin, Texas).
- Trial name
- SUMO (NCT01322737)
- Testing
- Tissue Access and Resection System
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Colon Cancer, Colon Polyp
Quad Resection (Hot Snare vs Cold Snare vs Hot EMR vs Cold EMR)
The study will compare the use of cold snare, hot snare, cold EMR, and hot EMR for polyp resection. Although previous studies have compared two of the potential resection methods, no previous study has evaluated all four of the…
- Conditions
- Colon Cancer, Colon Polyp, Colon Adenoma
- Trial name
- NCT03462706
- Testing
- Cold Snare, Hot Snare, Cold EMR
- Where
- United States
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Indiana University
Colon Cancer
Cancer Control Following Polypectomy
This study evaluates strategies for the surveillance of post-polypectomy patients for the control of bladder cancer
- Trial name
- NCT00591279
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Colorectal Adenoma, Colorectal Lesions
Cold Snare Versus Cold Forceps Polypectomy for Small Lesions
The goal of this clinical trial is to compare the efficacy and the safety of a new device for cold forceps polypectomy (CFP)- a special jumbo forceps- to cold snare polypectomy (CSP) for small colorectal lesions, without adding…
- Trial name
- Cold-SNAPS (NCT06970808)
- Testing
- Sampling from the resection margins
- Where
- Italy
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Azienda USL Modena
Polyp Colorectal, Endoscopic Mucosal Resection
Structured TXI-RDI Integration for Endoscopic Resection
The goal of this clinical research study is to learn whether two advanced imaging tools, called Texture and Color Enhancement Imaging (TXI) and Red Dichromatic Imaging (RDI), can make the removal of large colon polyps safer…
- Trial name
- STRIkER (NCT07474844)
- Testing
- Texture and Color Enhancement Imaging (TXI) and Red Dichromatic Imaging (RDI), High Definition White Light Endosocopy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Colo-rectal Cancer, Polyp of Colon
Evaluation of EverLift in the Performance of Polypectomy for Polyps 4-9mm
The focus of the study is to evaluate impact of submucosal injection of EverLift in achieving complete resection during polypectomy of polyps 4-9mm during colonoscopy.
- Conditions
- Colo-rectal Cancer, Polyp of Colon, Adenomatous Polyp of Colon
- Trial name
- NCT04551014
- Testing
- Use of EverLift, Without use of EverLift
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Stanford University