Clinical trials: Polypectomy
Post Polypectomy Bleeding in Anticoagulated Patients, Gastrointestinal Hemorrhage
Hemorrhage Following Small Polyp Resection in the Colon in Anticoagulated Patients
One of the well-known of complications post colonic polypectomy is bleeding usually occuring in the 2-week period following the procedure. Patients treated with oral anticoagulation (e.g.
- Trial name
- NCT02375646
- Testing
- Warfarin, LMW Heparin
- Volunteers
- 286 people
- Sponsor
- Hadassah Medical Organization
Colo-rectal Cancer, Polyp of Colon
Evaluation of Cold Forcep and Cold Snare Polypectomy for Polyps Less Than or Equal to 3mm in Size During Colonoscopy
The focus of the study is to evaluate impact of cold forcep and cold snare in achieving complete resection during polypectomy of polyps <=3mm during colonoscopy.
- Conditions
- Colo-rectal Cancer, Polyp of Colon, Adenomatous Polyp of Colon
- Trial name
- NCT04551001
- Testing
- Cold forcep polypectomy, Cold snare polypectomy
- Where
- United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Stanford University
Colonic Polyp
Injured Submucosal Arteries After CSP for 10-19 mm Nonpedunculated Colorectal Polyps.
Cold polypectomy has the advantages of simple operation, less time-consuming and fewer complications. Guidelines have recommended cold snare polypectomy (CSP) to resect small polyps sized <9 mm.
- Trial name
- NCT05930041
- Testing
- Experimental CSP, Active Comparator HS-EMR
- Where
- Japan
- Volunteers
- 124 people
- Sponsor
- Showa Inan General Hospital
Pedunculated Colorectal Polyps, Haemorrhage
Underwater Endoscopic Mucosal Resection Versus Metal Clips With Hot Snare Polypectomy for Resection of Big Pedunculated Colorectal Polyps
Endoscopic resection of pedunculated polyps mainly focuses on how to prevent bleeding, and also needs to pay attention to the convenience of resection and the integrity of resection, which means that different endoscopic…
- Trial name
- NCT06097637
- Testing
- underwater endoscopic mucosal resection, hot snare polypectomy
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Ningbo No. 1 Hospital
Polyp Gallbladder
Management Strategy of Polypoid Lesions of the Gallbladder
We retrospectively review a single-center cohort of gallbladder polyps from January 2015 to May 2020. Univariate and multivariable analyses were performed to extract potential risky factors of neoplastic polyps.
- Trial name
- NCT04762797
- Testing
- Non
- Where
- China
- Volunteers
- 672 people
- Sponsor
- Peking Union Medical College Hospital
Gastric Polyps, Intestinal Polyps
Recurrence After Gastric and Intestinal Polyp Resection
This is a retrospective and prospective cohort study designed to evaluate the recurrence rate and identify risk factors after endoscopic resection of gastric and intestinal polyps.
- Conditions
- Gastric Polyps, Intestinal Polyps, Colon Polyps, Colorectal Polyps
- Trial name
- RAGIP (NCT07314554)
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- LanZhou University
Polyp of Large Intestine, Colonic Polyps
Efficacy and Safety of a New Polypectomy Snare for Cold-polypectomy for Small Colorectal Polyps
Colorectal cancer is a major cause of morbidity and mortality in Western countries. Scientific studies have shown that endoscopic polypectomy is efficacious in preventing CRC incidence and mortality.
- Conditions
- Polyp of Large Intestine, Colonic Polyps, Colon Nos Polypectomy Tubular Adenoma, Complications
- Trial name
- NCT02245854
- Testing
- Exacto™
- Where
- 3 sites in Italy
- Volunteers
- 250 people
- Sponsor
- Istituto Clinico Humanitas
Sinusitis, Nasal Polyps
Pilot Study of The EPIC Trial
Chronic sinusitis is one of the most common chronic diseases in North America, with over 5% of the Canadian population affected by the disease. Until now, treatment with surgery has been performed only in the operating room.
- Trial name
- NCT02533206
- Testing
- Endoscopic Polypectomy Performed in Clinic, Functional Endoscopic Sinus Surgery (FESS)
- Where
- 5 sites in Canada
- Volunteers
- 20 people
- Sponsor
- Ottawa Hospital Research Institute
Endoscopic Polypectomy
Prospective Study on Polypectomy Complications: SPoC.
Colonoscopy has been shown to reduce both the colo-rectal cancer incidence and mortality, due to its capability to detect and remove precancerous lesions.
- Trial name
- NCT02007395
- Volunteers
- 5,170 people
- Sponsor
- Valduce Hospital
10-20 mm Pedunculated Colorectal Polyp
Investigation of Cold Snare Polypectomy for Removing 10-20 mm 0-Ip Colorectal Polyp
This is a multicenter, single-arm feasibility study conducted across multiple hospitals in Taiwan. The goal of this trial is to evaluate whether cold snare polypectomy is a feasible and safe method for removing 10-20 mm…
- Trial name
- NCT07114380
- Testing
- Cold snare polypectomy
- Where
- 5 sites in Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Colorectal Cancer, Lymph Node Metastasis
Multicentric Study About Pathological Risk Factors for Lymph Node Metastasis in Malignant Colorectal Polyps
Colorectal cancer screening showed an increased incidence of malignant colorectal polyps pT1 after endoscopic excision. Their management is not yet standardized, for the presence of histological features increasing early lymph…
- Conditions
- Colorectal Cancer, Lymph Node Metastasis, Colorectal Polyp
- Trial name
- POST-1 (NCT03588416)
- Where
- Italy
- Volunteers
- 615 people
- Sponsor
- Dario Parini
Colonic Polyps
Cold Snare,Hot Snare and APC Polypectomy for the Complete Removal of Small Left Sided Colon Polyps
Given the limited existing data regarding the advantages and limitations of the existing techniques in the removal of colonic polyps the investigators designed a prospective study in order to compare cold snare vs hot snare vs…
- Trial name
- NCT02479893
- Testing
- polypectomy
- Where
- Greece
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Evangelismos Hospital
Polyp of Colon
Prevention of Post-Polypectomy Colorectal Bleeding by Clips in Patients on Anticoagulants
This observational study aims to retrospectively determine if clips can prevent post-polypectomy bleeding in adults who have received restarted anticoagulants after a colorectal polypectomy, using a large, single-center patient…
- Trial name
- PiCAnt (NCT07007598)
- Testing
- Hemostatic clip
- Where
- Germany
- Volunteers
- 10,000 people
- Sponsor
- Helios Kliniken Schwerin
Colonic Polyp, Sedation Complication
A Comparison of Remimazolam Besylate and Propofol Sedation in Patients Undergoing Colonoscopic Polypectomy
The goal of this prospective, randomized, controlled study is to compare remimazolam besilat/sufentanyl and propofol/sufentanyl in patients during colonoscopic polypectomies procedures.
- Trial name
- Bypro (NCT07456111)
- Testing
- Remimazolam besylate, Propofol
- Where
- Croatia
- Volunteers
- 90 people
- Sponsor
- Clinical Hospital Centre Zagreb
Colorectal Cancer
Endoscopic Versus Surgical Treatment for T1 Colorectal Cancer
The implementation of population screening programs for colorectal cancer (CRC) has led to a considerable increase in the prevalence T1 CRC originating on polyps amenable by endoscopy.
- Trial name
- EpiT1 (NCT04150081)
- Testing
- Surgery or Endoscopic treatment
- Where
- Spain
- Volunteers
- 1,400 people
- Sponsor
- Hospital Clinic of Barcelona
Colorectal Adenoma With Mild Dysplasia, Colorectal Adenoma With Severe Dysplasia
Piecemeal Versus En Bloc Resection of Large Rectal Adenomas
Currently, colonoscopy is the safest way to detect bowel tumors and polyps, since these can be biopsied and removed in one working process.
- Conditions
- Colorectal Adenoma With Mild Dysplasia, Colorectal Adenoma With Severe Dysplasia, Colorectal Adenomatous Polyp, Colorectal Low Grade Intraepithelial Neoplasia
- Trial name
- PERLA (NCT02238938)
- Testing
- en-bloc resection, piecemeal resection
- Where
- 6 sites in Germany, United Kingdom
- Volunteers
- 110 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Colon Polyps, Polypectomy
Clinical Study to Compare Cold Snare Underwater Polypectomy to Cold Snare Conventional Polypectomy for Colon Polyps [COLDWATER Study]
Colon cancer is internationally the third cause of deaths from a malignant disease. Screening colonoscopy in adults >45 years of age aims at the early diagnosis and treatment colon polyps that are precancerous lesions.
- Trial name
- COLDWATER (NCT05273697)
- Testing
- Underwater Cold Snare Polypectomy, Conventional Cold Snare Polypectomy
- Where
- Greece
- Volunteers
- 396 people
- Sponsor
- National and Kapodistrian University of Athens
Post-polypectomy Bleeding, Colorectal Polyp
Argon Plasma Coagulation and Clip for the Prophylaxis of Post-polypectomy Bleeding After Hot Snare Polypectomy
Discuss the efficacy and safety of argon plasma coagulation （APC）in comparison with clip closure for preventing colorectal post-procedure bleeding（PPB） after hot snare polypectomy（HSP）; analyze the risk factors and the…
- Trial name
- APC、HSP (NCT05250518)
- Testing
- argon plasma coagulation, clip closure
- Where
- China
- Volunteers
- 1,017 people
- Sponsor
- Renmin Hospital of Wuhan University
Colonic Polyp
Impact of Augmented Reality in Polypectomy Skills Acquisition in Simulation-based Endoscopy Training
Simulation-based training (SBT) is a safe and effective strategy for improving skills development in gastrointestinal endoscopy.
- Trial name
- NCT03826069
- Testing
- Augmented reality-based curriculum, Conventional Simulation Curriculum
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Colorectal Polyp
Assessing Endoloop-assisted Polypectomy in Patients With Antiplatelet Therapy
The aims of this study were to examine: 1) safety and feasibility of antiplatelet therapy interruption 7 days prior to polypectomy in patients with long-term antiplatelet therapy; 2) safety and feasibility of endoloop assisted…
- Trial name
- NCT01800656
- Testing
- Endoloop-assisted "ligate and let go" colorectal polypectomy, Endoloop-assisted snare colorectal polypectomy
- Volunteers
- 36 people
- Sponsor
- Dr Milutin Bulajic