Clinical trials: Polypectomy
Colon Polyps
Safety of Endoscopic Resection of Large Colorectal Polyps: A Randomized Trial.
The effectiveness of colonoscopy in reducing colorectal cancer mortality relies on the detection and removal of neoplastic polyps.
- Trial name
- NCT01936948
- Testing
- Clip closure
- Where
- United States
- Volunteers
- 928 people
- Sponsor
- White River Junction Veterans Affairs Medical Center
Polyp of Large Intestine
Cold Snare Polypectomy Vs. Cold Forceps Polypectomy Using Narrow-band Imaging Endoscopy for Removal of Diminutive Colorectal Polyps
The purpose of this study is to compare cold snare polypectomy and cold forceps polypectomy using narrow-band imaging endoscopy for removal of diminutive colorectal polyps.
- Trial name
- NCT02201147
- Testing
- Cold biopsy polypectomy, Cold snare polypectomy
- Where
- South Korea
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Soonchunhyang University Hospital
Colon Polyp
A First-in-human Clinical Trial Evaluating a Novel Colonic Intraluminal Endoscopic Support Structure (CIESS)
The aim of the first-in-human clinical trial is to evaluate the feasibility of performing colonoscopic polypectomy with a novel colonic intraluminal endoscopic support structure (CIESS) in-situ
- Trial name
- NCT07311590
- Testing
- Colonic Intraluminal Endoscopic Support Structure
- Volunteers
- 4 people
- Sponsor
- JurongHealth
Polyp of Colon, Gastrointestinal Bleeding
Polypectomy With Hot vs Cold Snare in Small Colonic Lesions
Colonoscopy is the technique of choice for the diagnosis and prevention of colorectal cancer (CRC). The identification and extirpation of adenomas decreases the incidence of CRC by up to 76%.
- Conditions
- Polyp of Colon, Gastrointestinal Bleeding, Colonic Adenoma
- Trial name
- Polypech-c (NCT03783156)
- Testing
- hot snare, cold snare
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Hospital del Rio Hortega
Endometrial Polyp
The Effect of Levonorgestrel Intrauterine System in Preventing Endometrial Polyps Recurrence
The goal of this clinical trial is to determine whether the LNG-IUS is more effective to that of expectant in preventing endometrial polyp recurrence after hysteroscopic polypectomy.
- Trial name
- NCT06620939
- Testing
- Levonorgestrel Intrauterine System (LNG-IUS)
- Volunteers
- 558 people
- Sponsor
- Zhang Jian
Colorectal Neoplasms
Underwater Resection of Non-pedunculated Colorectal Lesions
The aim of this study is to compare the efficacy of underwater resection (polypectomy) versus conventional polypectomy techniques for small and large colorectal lesions identified during colonoscopy.
- Trial name
- NCT02889679
- Testing
- Underwater resection, Conventional (gas distended colon) resection, Standard polypectomy
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- VA Northern California Health Care System
Colorectal Cancer, Colorectal Neoplasms
Early Detection of Advanced Adenomas and Colorectal Cancer
This study aims to develop a highly sensitive, specific, and cost-effective blood assay for early detection of colorectal adenomas and cancer, using advanced machine learning and state-of-the-art biological analyses.
- Conditions
- Colorectal Cancer, Colorectal Neoplasms, Colorectal Polyp, Colorectal Adenocarcinoma
- Trial name
- AACRC (NCT06342440)
- Testing
- DENEB
- Where
- 6 sites in United States, China and 3 more
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Polyp Colorectal
The Clinical Effect of Normal Diet and Absolute Diet on Post-polypectomy Patients: an Open-label, Randomized Controlled Trial
There is no evidence to prove the impact of post-procedural diet on post-polypectomy bleeding (PPB) or delayed perforation. No relevant study has been conducted and it is yet to be determined if absolute diet is necessary for…
- Trial name
- NCT03989791
- Testing
- absolute diet, normal diet
- Volunteers
- 406 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Safety Issues
Safety of Propofol Sedation ( > 200 mg) for Colonoscopy.
This study examines that the use of >200 mg of propofol sedation enables patients to drive home safely after outpatient colonoscopy.
- Trial name
- NCT05213208
- Testing
- Propofol
- Where
- Japan
- Volunteers
- 300 people
- Sponsor
- Showa Inan General Hospital
Colonic Polyps, Surveillance
Large Overuse of Post-polypectomy Surveillance Colonoscopy
In colorectal cancer screening era a huge burden of medical resources has been applied to surveillance. Although the adherence to post-polipectomy recommendations is a advocated as a mainstay for quality assurance colonoscopy…
- Conditions
- Colonic Polyps, Surveillance, Colonoscopy
- Trial name
- NCT01458093
- Testing
- colonoscopy
- Where
- Italy
- Volunteers
- 7,081 people
- Sponsor
- Valduce Hospital
Colorectal Cancer, Colorectal Polyp
Predicting Risk for Post-polypectomy Colorectal Cancer
This originated as an observational study of Kaiser Permanente Northern California (KPNC) patients with a history of adenoma diagnosed by colonoscopy who received a subsequent surveillance colonoscopy between 2014 and 2019.
- Conditions
- Colorectal Cancer, Colorectal Polyp, Colorectal Adenoma, Neoplasm, Colorectal
- Trial name
- PREDICT (NCT05606081)
- Testing
- Logistic regression risk model
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Gastroenterology
A Randomized Clinical Trial of Shenbai Granules in Reducing Recurrence of Colorectal Adenoma
This study evaluates Shenbai Granules in Prevention of Colorectal Adenomatous Polyp Recurrence After Colonoscopy.Half of participants will receive Shenbai Granules,while the other half will receive a placebo.
- Trial name
- NCT03616444
- Testing
- Shenbai Granules
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Jiangsu Famous Medical Technology Co., Ltd.
Polyp of Colon
Linked Color Imaging Versus White Light Endoscopy for the Evaluation of Scars of Non-pedunculated Polyps. LCI Scar Study.
Careful inspection and evaluation of the post-polipectomy scars of polyps greater than 20 mm looking for residual polyp is mandatory. LCI has demonstrated to improve polyp and adenoma detection rate in previous studies.
- Trial name
- LCIScar (NCT04899700)
- Testing
- Linked Color Imaging, White light endoscopy
- Where
- 2 sites in Spain
- Volunteers
- 173 people
- Sponsor
- Hospital Clinic of Barcelona
Colonic Polyp, Intestinal Polyp
Cold Snare Polypectomy Versus Hot Snare Polypectomy for Diminutive and Small Colorectal Polyps
Background:The optimal technique for removal of diminutive or small colorectal polyps is debatable. Objective:To compare the complete resection rates of cold snare polypectomy (CSP) and hot snare polypectomy (HSP) for the removal…
- Trial name
- CSPVsHSP (NCT02717598)
- Testing
- cold snare polypectomy, hot snare polypectomy
- Where
- China
- Volunteers
- 198 people
- Sponsor
- Wulumuqi General Hospital of Lanzhou Military Command
Polyps
Thin Wire Versus Thick Wire Snare for Cold Snare Polypectomy of Diminutive Polyps
Cold snare polypectomy (CSP) is now common practice and has proven to be a safe and effective technique for removal of diminutive polyps. Both thick and thin wire snares are now commonly used for CSP.
- Trial name
- NCT02581254
- Testing
- Thin Wire Snare, Thick Wire Snare
- Where
- Australia
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- Western Sydney Local Health District
Colorectal Polyp
Compare Bleeding Risk Between Cold and Hot Snaring Polypectomy for Small Colorectal Polyp: a Randomized Control Trial
In this randomized control trial the investigators aim to compare the bleeding complication between cold snaring and hot snaring polypectomy with a large sample size.
- Trial name
- NCT03373136
- Testing
- Polypectomy
- Where
- Taiwan
- Volunteers
- 4,270 people
- Sponsor
- National Taiwan University Hospital
Colorectal Polyp
Assessing Endoloop-assisted Polypectomy in Patients With Antiplatelet Therapy
The aims of this study were to examine: 1) safety and feasibility of antiplatelet therapy interruption 7 days prior to polypectomy in patients with long-term antiplatelet therapy; 2) safety and feasibility of endoloop assisted…
- Trial name
- NCT01800656
- Testing
- Endoloop-assisted "ligate and let go" colorectal polypectomy, Endoloop-assisted snare colorectal polypectomy
- Volunteers
- 36 people
- Sponsor
- Dr Milutin Bulajic
Colo-rectal Cancer, Polyp of Colon
Evaluation of Cold Forcep and Cold Snare Polypectomy for Polyps Less Than or Equal to 3mm in Size During Colonoscopy
The focus of the study is to evaluate impact of cold forcep and cold snare in achieving complete resection during polypectomy of polyps <=3mm during colonoscopy.
- Conditions
- Colo-rectal Cancer, Polyp of Colon, Adenomatous Polyp of Colon
- Trial name
- NCT04551001
- Testing
- Cold forcep polypectomy, Cold snare polypectomy
- Where
- United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Stanford University
Colorectal Cancer
Efficacy of the Third Eye Retroscope Auxiliary Imaging System
The purpose of this study is to demonstrate efficacy of the Avantis Third Eye Retroscope auxiliary imaging system. The primary objective of this study is to assess the degree to which incorporating the Third Eye Retroscope…
- Trial name
- NCT00657371
- Testing
- Third Eye Retroscope Auxiliary Imaging System
- Where
- 7 sites in United States
- Volunteers
- 288 people
- Sponsor
- M.D. Anderson Cancer Center
Cold Snare Resection, Hot Snare Resection
Efficacy and Safety Research of Cold Snare Polypectomy and Hot Snare Polypectomy in the Treatment of 4-9 mm Diameter Colorectal 0-Isp and 0-Ip Polyps: a Prospective, Multicenter, Randomized Controlled Study(FAST -REST Study)
This study will evaluate the efficacy and safety of cold snare polypectomy(CSP) and hot snare polypectomy(HSP) in the treatment of colorectal 4-9mm 0-Isp and 0-Ip polyps, and compare the complete resection rate, postoperative…
- Conditions
- Cold Snare Resection, Hot Snare Resection, Polyps of Colon
- Trial name
- NCT06658561
- Testing
- cold snare polypectomy, hot snare polypectomy
- Where
- China
- Volunteers
- 982 people
- Sponsor
- Ruijin Hospital