Clinical trials: Polypharmacy Patients
Medication Adherence, Medication Compliance
Connected Healthcare for Individuals Living at Home With Chronic Conditions
Managing and taking medications as prescribed can be a difficult task. This is especially true for older adults living at home with chronic conditions while managing multiple prescribed medications.
- Conditions
- Medication Adherence, Medication Compliance, Medication Nonadherence, Hypertension
- Trial name
- NCT04339296
- Testing
- Spencer
- Where
- Canada
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Alberta Health Services, Calgary
Hypertension
Reduction Of Dietary Salt Intake To Control Systolic Blood Pressure In Hypertensive Older Patients
REPRESS is an open label, pragmatic, multicenter, randomized controlled phase III trial with blinded endpoint with 1:1 (intervention to control arm) allocation ratio.
- Trial name
- REPRESS (NCT05976477)
- Testing
- educational intervention
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- Mario Negri Institute for Pharmacological Research
Medication Adherence, Patient Compliance
Efficacy of a Intervention to Reduce Medication Errors and Improve Adherence
The purpose of this study is to demonstrate that an intervention based on the motivational interview directed to patients with polypharmacy to improve the Therapeutic Adherence and to reduce the errors of Medication in major…
- Trial name
- ATEM-AP (NCT01291966)
- Testing
- Motivational interview
- Where
- Spain
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Reina Sofia de Cordoba
Polypharmacy, Multiple Chronic Conditions
Protocol for a Multi-site Pilot Study of the OptiMed Clinical Trial
Background: Optimal medication management is one of the essential preconditions for polymedicated home-dwelling older adults with multiple chronic conditions to remain at home and preserve their quality of life and autonomy.
- Trial name
- OptiMed (NCT06688591)
- Testing
- Intervention programme to optimise medication management and prevent MRPs
- Volunteers
- healthy volunteers welcome
- Sponsor
- HES-SO Valais-Wallis
Polypharmacy
Measuring the Impact of an Interdisciplinary Polypharmacy Clinic Within a Patient-centered Medical Home
Title: Measuring the impact of an interdisciplinary polypharmacy clinic within a patient-centered medical home Objectives: The primary objective of this project will be to track the types of interventions made in an…
- Trial name
- NCT02077725
- Testing
- interdisciplinary polypharmacy clinic visit
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ohio State University
Frail Elderly Syndrome
Subjective Factors of Polymedication in the Elderly: a Qualitative Study of the Perceptions of Patients, Relatives and Referent Physicians.(DOSAGE)
The DOSAGE Study is a qualitative transversal study aiming to describe and understand the subjective factors of polymedication in the elderly population (75 years old and more), defined as 10 simultaneous drugs.
- Trial name
- DOSAGE (NCT03309228)
- Testing
- individual interviews
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Healthy
Rationalisation of Polypharmacy in the Elderly by the RASP Instrument
The aim of this study is to determine whether a clinical pharmacist using the RASP list (RASP = Rationalisation of home medication by an adjusted STOPP-list in older patients; STOPP = Screening Tool of Older Persons' potentially…
- Trial name
- RASP (NCT01513265)
- Testing
- Pharmaceutical care plan, mostly based on the RASP
- Where
- Belgium
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Fall, Fall Injury
A Clinical Decision Support System and Patient Portal for Preventing Medication-related Falls in Older Patients
Falls in older adults represents a growing public health challenge. The use of certain medication is recognized as an important modifiable risk factor for falls.
- Conditions
- Fall, Fall Injury, Fall Patients, Accidental Fall
- Trial name
- ADFICE_IT (NCT05449470)
- Testing
- CDSS, Patient Portal
- Where
- 10 sites in Netherlands
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Caregivers of Multi-pathological and Polypharmacy Adults
Safe Use of Medication at Home by Caregivers. Experimental Study
Experimental study to test the effectiveness of a psychoeducational intervention using virtual reality, aimed at caregivers of multi-pathological and polypharmacy persons to promote safer medication use at home.
- Trial name
- NCT05247801
- Testing
- Psychoeducational intervention for safe medication use at home + Medication dosing device, Medication dosing device
- Where
- Spain
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Universidad Miguel Hernandez de Elche
Frailty, Cognitive Impairment
Orthopedic Procedures and Postoperative Delirium in Older Adults in the Czech Republic
This multicenter, prospective, non-interventional observational study (ORTOPODCZ) investigates the association between preoperative cognitive impairment and postoperative delirium (POD) in older adults undergoing elective total…
- Conditions
- Frailty, Cognitive Impairment, Older Adults, Hip Arthroplasty
- Trial name
- ORTOPODCZ (NCT07432009)
- Where
- 7 sites in Czechia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Tomas Bata Hospital, Czech Republic
Polypharmacy, Adverse Drug Reaction
Deprescribing of Symptomatic Medications in Rehabilitative or Subacute Care Patients
Deprescribing is a systematic method of withdrawing potentially inappropriate or unnecessary medications and is warranted in the elderly due to the high prevalence of polypharmacy.
- Trial name
- NCT03354845
- Testing
- Deprescribing intervention
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bright Vision Hospital
Dementia, Potentially Inappropriate Medication Use
e-ALIGN: A Patient Portal-based Intervention to Align Medications With What Matters Most
The overarching goal of this study is to pilot an intervention in which older adults with mild cognitive impairment and dementia and the older adult's care partners are identified in primary care and provided with educational…
- Conditions
- Dementia, Potentially Inappropriate Medication Use, Mild Cognitive Impairment (MCI)
- Trial name
- e-ALIGN (NCT07454824)
- Testing
- e-ALIGN Patient-Portal Deprescribing
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Comorbidity, Medication Therapy Management
Effectiveness of a Medication Wallet Card
This study evaluates whether or not the use of a medication wallet card in patients over 70 taking 5 or more medications promotes self-efficacy with regards to coping with illness, understanding medications, and staying healthy.
- Conditions
- Comorbidity, Medication Therapy Management, Polypharmacy
- Trial name
- NCT02820129
- Testing
- Medication Wallet Card, Reminder Card
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- McMaster University
Psychiatric Disorder
Using Pharmacogenetics to Identify Patients With Polypharmacy at Risk of Medication Adverse Effects
The Researchers are trying to learn more about how individuals break down and process medications based on their genes. The Researchers want to find out whether subjects will have fewer side effects if they take different…
- Trial name
- NCT03748355
- Testing
- Pharmacogentic Analysis
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic