Clinical trials: Polyphenols
Oxidative Stress
Absorption Kinetics of Polyphenols in Angel's Plant (Angelica Keiskei)
The absorption kinetics of polyphenols in angel's plant (Angelica keiskei), which is a dark green leafy vegetable rich in antioxidant nutrients, will be determined in older adults in this pilot study.
- Trial name
- NCT00721643
- Testing
- angel's plant (Angelica keiskei)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Tufts University
Blood Glucose
A Pilot Study Evaluating Oat Polyphenols on Post-prandial Glucose Response
The trial will use a two period acute double-blind cross-over design to compare the effects of a serving of oatmeal containing high or low amounts of avenanthramides (AV) on post-prandial blood glucose response in healthy adults.
- Trial name
- NCT04260425
- Testing
- Serving of oatmeal made from low avenanthramides oats and water, Serving of oatmeal made from high avenanthramides oats and water
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Body Weight
Effect of Polyphenol-rich Dark Chocolate on Body Weight in Overweight and Obese Adults
The aim of this study is to investigate if dark chocolate rich in polyphenols decreases body weight/ body fat in the overweight and obese adult population.
- Trial name
- NCT01749852
- Testing
- Polyphenol-rich Dark chocolate
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Queen Margaret University
Muscle Recovery
Investigating the Efficacy of Low or High Dose Tart Cherry on Recovery From Exercise Induced Muscle Damage and Establishing Its Molecular Mechanisms of Action
To determine the dose-response effects of 10-day tart cherry product consumption (0, 30 ml, and 60 ml) on knee extensor isometric strength 24-h and 48-h after muscle damaging exercise and to elucidate the mechanisms of action for…
- Trial name
- NCT04725149
- Testing
- 500 ml base solution, 500 ml containing 30 ml tart cherry concentrate diluted with water and base solution, 500 ml containing 60 ml tart cherry concentrate diluted with water only
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Polyphenolic Compounds and Metabolism
Acute Effects of Grape Seed Extract on Insulin Sensitivity and Oxidative Stress and Inflammation Markers.
The proposed study aims to investigate that consumption of grape seed extract (GSE) would improve antioxidant status and impaired insulin action following consumption of a pro-oxidative high carbohydrate, high fat (HCHF) meal in…
- Trial name
- GSE2 (NCT01995643)
- Testing
- Active Capsule
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Healthy Nutrition
Effect of the Intake of Corbella Extra Virgin Olive Oil on the Microbiota-gut-brain Axis in Healthy Adults (HEVOOC)
The consumption of the improved extra virgin olive oil (EVOO) of the Corbella variety could have a beneficial effect on the microbiota-intestine-brain axis (MGBA).
- Trial name
- HEVOOC (NCT05898113)
- Testing
- EXTRA VIRGIN OLIVE OIL, OLIVE OIL LOW POLYPHENOL
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Obesity
Grape Polyphenols and Second-meal Effect
The aim of this is study is to evaluate the effects of a single intake of grapes (a polyphenol-rich food) in postprandial metabolism in subjects with obesity, including a first intake (high-fat breakfast) after overnight fasting…
- Trial name
- GRAPESECOND (NCT03741218)
- Where
- Spain
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- National Research Council, Spain
Inflammation, Heart Failure
Beer, Marathon, Genetics, Inflammation and the Cardiovascular System: Be-MaGIC-Trial
The purpose of the study is to determine the myocardial function and vascular adaptation after strenuous exercise in association with consumption of polyphenols.
- Conditions
- Inflammation, Heart Failure, Sudden Cardiac Death
- Trial name
- Be-MaGIC (NCT00933218)
- Testing
- polyphenols (non-alcoholic beer), beverage without polyphenols
- Where
- Germany
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Endothelial Function
Dose-dependent Effects of Blueberry Polyphenols on Endothelial Function in Healthy Individuals
The purpose of this study is to assess the impact of acute blueberry polyphenol intake on endothelial function of healthy volunteers.
- Trial name
- BB2 (NCT01829542)
- Testing
- Freeze-dried blueberry powder dissolved in water, Control
- Where
- United Kingdom
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Reading
Postprandial Hypoglycemia, Age-Related Memory Disorders
The Scottish Fruit Study
The purpose of this study is to determine if new varieties of fruits grown in Scotland which can adapt better to climate change namely, honeyberries and cherries, have the same health benefits as established fruits such as…
- Trial name
- NCT05513404
- Testing
- Honeyberry, Cherry, Raspberry
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Obesity
Enhancing Efficacy of Mango Polyphenols in Lean and Obese
The objective of this research is to determine beneficial impact of mango phytochemicals in lean and obese individuals for cognitive function and gut health.
- Trial name
- NCT04970589
- Testing
- Mango, Probiotics
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Oxidative Stress, Physical Activity
Effect of the Combination of Pterostilbene Cocrystal With Silybin and Nicotinamide Riboside on Exercise-Induced Oxidative Stress
This study aims to evaluate the effects of the dietary supplement ccPT-SIL-NR, which contains pterostilbene (ccPT), silybin (SIL), and nicotinamide riboside (NR), on oxidative stress markers after a high-intensity exercise…
- Conditions
- Oxidative Stress, Physical Activity, Antioxidant Effect
- Trial name
- PT-SILAOX (NCT07024966)
- Testing
- Pterostilbene-silybin-nicotinamide riboside, Control Group
- Where
- Spain
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Fundació Eurecat
Healthy Control
Metabolism of Bioactive Dietary Polyphenol Preparation (BDPP)
This study will characterize the clinical pharmacology of a select bioactive polyphenol-rich preparation (Bioactive Dietary Polyphenol Preparation, BDPP) comprised of a select Concord grape juice (CGJ), a select grape seed…
- Trial name
- NCT04421079
- Testing
- Trans-resveratrol, Concord grape juice, Grape seed polyphenol extract
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai