Clinical trials: Polyphenols
Stress, Psychological, Gut Bacteria
Polyphenols, Prebiotics, the Gut Microbiome and Stress
The aim of this study is to evaluate how different combinations of prebiotics and polyphenols affect the gut microbiota and perceived cognitive state.
- Trial name
- NCT05528575
- Testing
- Blueberry, cranberry, green tea extract, cocoa, GOS, Inulin, RS2, prebiotics and polyphenols
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Reading
Endotoxemia, Metabolic Syndrome
Effect of Cranberry and Agaves Extract on Microbiota and Intestinal Health
The growing prevalence of obesity and type 2 diabetes (T2D) is a major public health problem. Recent studies have clearly established that the gut microbiota plays a key role in the investigator's propensity to develop obesity…
- Conditions
- Endotoxemia, Metabolic Syndrome, Glucose Metabolism Disorders, Insulin Resistance
- Trial name
- Phenulin (NCT03800277)
- Testing
- Cranberry, Agaves
- Where
- Canada
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Laval University
Overweight and Obesity
Evaluation of Fiit-ns® in Health-related Quality of Life Improvement in Overweight and Obese Subjects
The purpose of this study is to evaluate the effects of a 16-week supplementation with a polyphenol-rich extract, Fiit-ns®, on improvement of health-related quality of life (HR-QOL) of overweight and obese volunteers, as compared…
- Trial name
- NCT03423719
- Testing
- Fiit-ns®
- Where
- Spain
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Fytexia
Healthy Non-smoker
Matrix on Fruit Constituent Bioavailability
Primary objective is to evaluate the influence of matrix on the bioavailability of key phytochemical constituents in fruits and their subsequent effect on chronic disease risk factors.
- Trial name
- FRT (NCT01908634)
- Testing
- Milk-based Strawberry Beverage without meal, Water-Based Strawberry Beverage without meal, Milk-based strawberry Beverage with meal
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Endothelial Function
Dose-dependent Effects of Blueberry Polyphenols on Endothelial Function in Healthy Individuals
The purpose of this study is to assess the impact of acute blueberry polyphenol intake on endothelial function of healthy volunteers.
- Trial name
- BB2 (NCT01829542)
- Testing
- Freeze-dried blueberry powder dissolved in water, Control
- Where
- United Kingdom
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Reading
Skin Aging
Effect of Oligopin® on Skin Ageing
Extrinsic or exogenous ageing is caused by repetitive exposure of the skin to harmful agents, while primary cause the exposure to ultraviolet (UV) radiation, known as photoageing, including solar effect.
- Trial name
- OLIGOSKIN (NCT04141059)
- Testing
- Oligopin
- Where
- Spain
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Technological Centre of Nutrition and Health, Spain
Type II Diabetes Mellitus
Effects of a Spiced Meat Patty on Inflammation in Men With Type 2 Diabetes
Polyphenols belong to the largest group of secondary metabolites produced by plants, mainly, in response to biotic or abiotic stresses such as infections, wounding, UV irradiation, exposure to ozone, pollutants, and other hostile…
- Trial name
- NCT01076829
- Testing
- Spice polyphenols
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Healthy Ageing
Effect of Polyphenol-rich Cocoa Products on Cognitive Function
This project aims to investigate whether consumption of cocoa polyphenols has an impact on cognitive function in individuals aged 50 to 60 years of age and if such an improvement is a result of an improvement in risk factors…
- Trial name
- NCT02996578
- Testing
- polyphenol rich chocolate bar, polyphenol rich cocoa powder, low polyphenol content chocolate bar
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Queen Margaret University
Inflammation
Banana Cultivars and Exercise Performance and Recovery
In a previous study at the Appalachian State University (ASU) Human Performance Laboratory at the North Carolina Research Campus (NCRC), investigators showed that cyclists ingesting about one-half of a banana with water every 15…
- Trial name
- NCT02994628
- Testing
- Water, Mini banana, Cavendish banana
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Healthy
Comparing the Effect of Whey and Soy Protein on the Absorption of Pomegranate Polyphenols in the Human Body
This study is comparing the quantity of active metabolites from consuming pomegranate juice in three different preparations. People who participate in this study will come in to the Center for a screening visit, which includes a…
- Trial name
- NCT02233478
- Testing
- Pomegranate Juice, Soybean Flour Protein, Soy Isolate Protein
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Healthy Adult, Cognitive Measures
Multivitamin Intervention and Cognitive Function
The purpose of this trial is to learn how a multivitamin combined blueberry polyphenol supplement (Vitals+) influences cognitive function in healthy adults.
- Trial name
- NCT06795789
- Testing
- Vitals+ (combined multivitamin and polyphenol supplement)
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Braincare Limited
Photoaging
Effects of Mango Intake on Skin Health and Gut Microbiome Changes in Postmenopausal Women
Mangos are a rich source of nutrients such as carotenoids, vitamin C and fiber, as well as polyphenols and phenolic acids such as mangiferin, ellagic acid, and gallotannins.
- Trial name
- NCT04869852
- Testing
- Food
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Healthy
Gut Microbial Metabolism of Polyphenols and Cardiovascular Health (StratiPol) (Stratification Study)
There is increasing interest in the effects of various food derived polyphenols on cardiovascular health. Several studies have demonstrated improvements in vascular function after intake of polyphenol rich foods.
- Trial name
- StratiPol (NCT03573414)
- Testing
- raspberry powder, milled flaxseed and soy milk
- Where
- United Kingdom
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- King's College London
Cardiovascular Diseases
Cardiovascular Benefits of Acai Polyphenols in Volunteers at Risk of Metabolic Syndrome
The purpose of this study is to carry out a randomized double blind controlled trial in 30 male subjects to investigate the effect of acai consumption on acute changes in vascular function, and to other cardiovascular markers.
- Trial name
- AF1 (NCT02292329)
- Testing
- Acai puree, frozen blended it with banana, Control Macronutrient matched
- Where
- United Kingdom
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Reading
Cognitive Performance, Mood
Effects on Cognitive Functions and Mood of Food Products Rich in Polyphenols
The purpose of this study is to investigate effects of a selected food product rich in polyphenol on cognitive performance and mood.
- Conditions
- Cognitive Performance, Mood, Cardiometabolic Risk Markers
- Trial name
- NCT02243956
- Testing
- Flavanol rich food product
- Where
- Sweden
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Lund University
Pre-hypertension, Hypertension
The Effects of Polyphenol-rich Berry Juice on Blood Pressure in Hypertensive Subjects
The purpose of this study is to investigate the effects of berry juices containing different levels of polyphenols on blood pressure and other cardiovascular risk factors.
- Trial name
- NCT01568983
- Testing
- Mana-juice, Optijuice
- Where
- Norway
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Healthy
Effects of Polyphenols Supplementation on Cycling Endurance
Endurance performance during high intensive exercises is mainly determined by the capacity of the aerobic metabolism. It generally induces muscle fatigue defined as the reversible decline in skeletal muscle contractile…
- Trial name
- NCT03214276
- Testing
- Vinitrox polyphenols
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Burgundy
Obesity, Overweight
The Effect of Citric Flavonoid on Endothelial Function
This randomized, double-blind, placebo-controlled, parallel study aims to determine the 6-week and acute effects of daily administration of a citrus flavonoid on cardiovascular and intestinal health as assessed by investigation…
- Trial name
- NCT02228291
- Testing
- Capsule containing citrus flavonoid
- Where
- Netherlands
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Inflammatory Disorder of the Cardiovascular System
Polyphenols Supplementation on Prostaglandin E2 in Women - Randomized Clinical Trial
The aim of this study was to evaluate the effect of polyphenol supplementation on plasma levels of prostaglandin E2 in women during the reproductive period.
- Trial name
- NCT02567617
- Testing
- Polyphenols
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Lipid Metabolism, Diabetes
Tea Extract, Blood Lipid and Dietary Fat
There are numerous factors known to determine the relative rate of lipid metabolism at rest between and within individuals, including: biological sex, endogenous carbohydrate availability, training status and, in particular…
- Trial name
- NCT03324191
- Testing
- Tea beverage, Tea extract (medium concentration), Tea extract (high concentration)
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Bath