Clinical trials: Polyps
Smell Loss, Chronic Rhinosinusitis (CRS)
Cognitive and Immunologic Profiles of Patients With Olfactory Dysfunction After Smell Training
A research study to assess the baseline olfactory function, mental health status, clinical severity, and immunological profile in patients with smell loss.
- Trial name
- CIPOD (NCT07681973)
- Testing
- Smell Training
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Polyps
Experience and Enhancement: Improving Colonoscopic Polyp Detection
The study looks at 2 hypotheses in 2 patient groups: 1. Are more experienced endoscopists better at detecting subtle lesions (polyps) on the lining of the colon (large bowel) than less experienced endoscopists? 2.
- Trial name
- NCT00237276
- Testing
- colonoscopy
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- London North West Healthcare NHS Trust
Colorectal Polyp
The Impact of Repeated Colonoscopic Insert Method on the Detection Rate of Adenomas in the Sigmoid Colon
Colorectal cancer (CRC) is a malignant tumour originating from the colorectal mucosal epithelium, with rising incidence and mortality rates.
- Trial name
- NCT06186778
- Testing
- secondary colonoscopy, conventional colonoscopy
- Where
- China
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Jianning Yao
Polyps, Cardiovascular Diseases
Lifestyle and Dietary Pattern in Relation to Precursor Lesions of Colorectal Cancer and Cardiometabolic Diseases
The association between lifestyle and dietary patterns with precursor lesions of colorectal cancer and cardiometabolic diseases is still unclear.
- Trial name
- NCT03708952
- Where
- 2 sites in China
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Colon Adenomas, Colon Polyps
Impact of Computer-aided Detection System on the Right Colon Adenoma Miss Rate
This is a prospective, multicenter randomized controlled trial designed to determine whether the use of computer-aided detection system could reduce the miss rates of adenomas, SSLs, and polyps in the proximal colon during tandem…
- Conditions
- Colon Adenomas, Colon Polyps, Sessile Serrated Lesion
- Trial name
- NCT07308743
- Testing
- Computer-aided detection-assisted colonoscopy, Conventional white-light colonoscopy
- Where
- China
- Volunteers
- 686 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Chronic Rhinosinusitis, Endoscopic Sinus Surgery
Perioperative Oral Steroids for Chronic Rhinosinusitis Without Polyps (CRSsNP)
While oral steroids have been shown to be effective in the management of patients with chronic rhinosinusitis with polyps, its role in treating chronic rhinosinusitis without polyps (CRSsNP) is ambiguous.
- Conditions
- Chronic Rhinosinusitis, Endoscopic Sinus Surgery, Chronic Rhinosinusitis Without Polyps, Oral Steroids
- Trial name
- NCT02748070
- Testing
- Prednisone, Flonase
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Stanford University
Colonic Adenomatous Polyps
Effectiveness and Safety of the Colonoscopy With "Visualization" Balloon
Colonoscopy has become the "gold standard" in detection of colonic polyps and colon cancer. However, colonoscopy causes significant abdominal discomfort and abdominal pain during and after the procedure, requiring intravenous…
- Trial name
- NCT02117232
- Testing
- Visualization balloon, Traditional CO2 insufflation colonoscopy
- Where
- United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Mercy Medical Center
Colorectal Neoplasms
Third Eye Retroscope Randomized Clinical Evaluation
The Third Eye® Retroscope® is a device that can be inserted through the instrument channel of a standard colonoscope to provide an additional, retrograde (or backward) view that reveals areas behind folds and flexures in the…
- Trial name
- TERRACE (NCT01044732)
- Testing
- Third Eye Retroscope
- Where
- 9 sites in United States, Belgium and 3 more
- Volunteers
- 448 people, healthy volunteers welcome
- Sponsor
- Avantis Medical Systems
Colorectal Polyps
Virtual Chromoendoscopy for Distal Polyps
To assess the accuracy of predicting histology with virtual chromoendoscopy for distal colorectal polyps according to the ASGE PIVI statement.
- Trial name
- NCT02217449
- Testing
- Prediction of histology
- Where
- Germany
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Adenoma Colon, Polyp of Colon
Computer-aided Detection of Colorectal Polyps
In this observational pilot study, we assess the diagnostic performance of an artificial intelligence sytem for automated detection of colorectal polyps.
- Trial name
- NCT04359355
- Testing
- Artificial Intelligence System for Detection of colorectal polyps
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Colon Polyp
Seoul National University Hospital Gangnam-Real Time Optical Diagnosis Program 2: Gangnam-READI2
Accurate optical diagnosis of colorectal polyps could allow a "resect and discard" strategy based on the results of the optical biopsy.
- Trial name
- NCT04350840
- Testing
- feedback
- Where
- South Korea
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Colo-rectal Cancer, Polyp of Colon
Computer Aided Detection of Polyps During Colonoscopy Procedures
The focus of the study is to evaluate impact on Adenomas Per Colonoscopy (APC) with a Computer Aided Detection (CAD) software assisting the gastroenterologist during a colonoscopy procedure.
- Conditions
- Colo-rectal Cancer, Polyp of Colon, Adenomatous Polyps
- Trial name
- NCT04195646
- Testing
- EndoVigilant CAD Software
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- EndoVigilant Inc
Colorectal Cancer, Polyp
Performance Evaluation of the NaviAid™ G-Eye System
The purpose of this study is to compare the additional diagnostic yield obtained by performing NaviAid™ G-Eye procedure vs. the diagnostic yield obtained by performing standard colonoscopy procedure.
- Conditions
- Colorectal Cancer, Polyp, Adenoma
- Trial name
- NCT01552200
- Testing
- Group A-Standard Colonoscopy, then NaviAid™ G-Eye procedure, Group B-NaviAid™ G-Eye procedure, then Standard Colonoscopy
- Where
- 4 sites in Germany, Israel
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Smart Medical Systems Ltd.
Nasal Polyps
Retrospective Study for Recurrent Nasal Polyposis
A retrospective study for patients with recurrent nasal polypi operated at Otorhinolaryngology Department, Sohag University Hospital will be carried out.
- Trial name
- NCT04804488
- Testing
- nasal polyp surgery
- Where
- Egypt
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Sohag University
Polyps Colorectal, Colonoscopy
Optical Diagnosis of Neoplasia Using Artificial Intelligence
Computer-aided diagnosis (CADx) for colonoscopy aims to enhance optical diagnosis but often underperforms when used alongside humans due to under-reliance on AI.
- Conditions
- Polyps Colorectal, Colonoscopy, Optical Biopsy, Colorectal Cancer Control and Prevention
- Trial name
- FAIR (NCT07158203)
- Testing
- CADx simultaneously, CADx delayed
- Where
- 2 sites in Norway, Spain
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Fundacin Biomedica Galicia Sur
Cancer Diagnosis, Liver Cancer, Adult
Raman Spectroscopy-Based Deep Learning Model for Early Pan-Cancer Early Diagnosis
The goal of this observational study is to explore whether a Raman-based, deep learning-assisted approach can be used to develop an effective method for early pan-cancer screening.
- Conditions
- Cancer Diagnosis, Liver Cancer, Adult, Cancer Screening, Colorectal Cancer (CRC)
- Trial name
- NCT06822413
- Testing
- No Interventions
- Where
- 4 sites in China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Colorectal Cancer (CRC), Colorectal Cancer and Pre-cancer Polyps
Examination of the Large Intestine With Camera Capsule in Patients With Blood Stream Infection With Gut-associated Bacteria
The goal of this observational study is to diagnose colorectal cancer or precancerous tumors in participants over the age of 18 hospitalized with blood stream infection with anaerobic gut-associated bacteria.
- Conditions
- Colorectal Cancer (CRC), Colorectal Cancer and Pre-cancer Polyps, Blood Stream Infection, Anaerobic Infection
- Trial name
- AB-care (NCT06919068)
- Testing
- Colon capsule endoscopy
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Bowel Preparation Scale, Adenoma Detection Rate
Comparison Between 3-L and 4-L Polyethylene Glycol in Bowel Preparation
High quality bowel preparation is essential for successful colonoscopy. This study aimed to assess the impact of the dose of Polyethylene Glycol(PEG) on the quality of bowel preparation.
- Trial name
- NCT03356015
- Testing
- 4L Polyethylene Glycol, 3L Polyethylene Glycol
- Where
- China
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Colonic Polyp, Colonic Neoplasms
Validation of Aer-O-Scope Colonoscope System Cecal Intubation
61 subjects (male or female) between the ages of 45 and 75 will undergo colonoscopy. The primary outcome is Cecal Intubation
- Conditions
- Colonic Polyp, Colonic Neoplasms, Colonic Diseases, Colon Adenoma
- Trial name
- NCT03949777
- Testing
- Aer-O-Scope Colonoscopy
- Where
- Israel
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- GI View Ltd.
Healthy, Chronic Rhinosinusitis With Nasal Polyps
Study Of PF-06817024 In Healthy Subjects, In Patients With Chronic Rhinosinusitis With Nasal Polyps And in Patients With Atopic Dermatitis
The purpose of this study is to evaluate safety, tolerability, pharmacokinetics, and pharmacodynamics of PF-06817024 in healthy volunteers, in participants with chronic rhinosinusitis, with nasal polyps and in participants with…
- Conditions
- Healthy, Chronic Rhinosinusitis With Nasal Polyps, Atopic Dermatitis
- Trial name
- NCT02743871
- Testing
- PF-06817024
- Where
- 20 sites in United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Pfizer