Clinical trials: Polyunsaturated Fatty Acids
Anorexia Nervosa
Study of Food Aversion in Patients With Anorexia Nervosa
This study uses a meal-challenge protocol to assess if patients with anorexia nervosa show a differential metabolism in response to food in comparison to healthy controls.
- Trial name
- NCT03100656
- Testing
- A breakfast sandwich
- Where
- 2 sites in United States, Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Type2 Diabetes
Fish, Polyunsaturated Fatty Acids Intake and Type 2 Diabetes
The role of fishery diet and polyunsaturated fatty acids (PUFA) in the development of type 2 diabetes (T2D) is heavily debated but evidence from large populations in China is scant.
- Trial name
- NCT03259321
- Volunteers
- 15,100 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Memory Impairment, Age-related Cognitive Decline
Development of an Innovative Health Ingredient From Marine By-products for the Healthy Aging
This interventional, randomised, placebo-controlled and double-blind study aims to evaluate the effect of a dietary supplementation with a blue fish hydrolysate derived from marine by-products, containing peptides and n-3…
- Trial name
- BRAINBOOSTER (NCT04910399)
- Testing
- Blue fish hydrolysate
- Where
- 2 sites in France
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Abyss Ingredients
Breast Milk Collection
Analysis of Lipids in Human Milk At Different Gestational Ages
Various studies have shown that the milk of a preterm infant differs from that of a term infant in the composition of micronutrients, vitamins, macronutrients, carbohydrates and proteins.
- Trial name
- NCT05989009
- Testing
- Breastfeeding
- Where
- 2 sites in Italy
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ospedale Buon Consiglio Fatebenefratelli
Hypertriglyceridemia
Effect of Consuming n-3 Polyunsaturated Fatty Acids Rich Foods on Triglyceride Concentration and Lipoprotein Composition
Hypertriglyceridemia is one of the most prevalent lipid profile disorders and is linked to a large proportion of mortality in Mexico and around the world.
- Trial name
- SALVIMEX (NCT07004777)
- Testing
- Isocaloric diet including chia and pumpkin seeds, Isocaloric diet
- Where
- Mexico
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Migraine, Omega-3 Polyunsaturated Fatty Acids
Omega-3 Fatty Acid in the Prevention of Migraine
To understand the clinical efficacy for omega-3 PUFAs migraine prevention.To uncover the underlying biochemical or neurophysiological mechanisms by which omega-3 PUFAs for migraine prevention.
- Trial name
- NCT04572789
- Testing
- Omega-3 polyunsaturated fatty acids, omega-6 PUFAs
- Where
- Taiwan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Kuang Tien General Hospital
Cardiovascular Diseases, Vasodilation
Effects of n-3 Polyunsaturated Fatty Acids and Antioxidants on Postprandial Hyperlipidemia and Vascular Function in Men
Diet has long been used as a way to provide enough nutrients to an individual in order to meet metabolic requirements. However, recent scientific advancements have suggested that beyond meeting nutrition needs, diet may also be…
- Trial name
- NCT00296595
- Testing
- Nutrition
- Where
- Canada
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Laval University
Atopic Dermatitis
The Effects of Polyunsaturated Fatty Acids (PUFA) on Allergic/Atopic Dermatitis
This clinical trial will study the effects of PUFA supplementation during pregnancy and lactation period on fatty acid composition in human milk and plasma of the mothers and the clinical outcome of atopic dermatitis in infants…
- Trial name
- NCT01936194
- Testing
- DHA+EPA, High Olive Oil, DHA
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mead Johnson Nutrition
Hypertension, Lipid Metabolism Disorders
Alpha-linolenic Acid and Blood Pressure
Rationale: Increased intakes of n-3 long chain polyunsaturated fatty acids eicosapentanoic acid (EPA) and docosahexaenoic acid (DHA), mainly found in fatty fish, are recommended for the prevention of coronary heart disease.
- Trial name
- VASALA (NCT02243969)
- Testing
- Flaxseed oil, high oleic sunflower oil (HOSF)
- Where
- Netherlands
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Cardiovascular Disease, Blood Pressure
Effect of Pumpkin Seeds on the Dietary Fatty Acid Intake and Blood Pressure in Women
The purpose of this study is to determine if the inclusion of 1.5 ounces of pumpkin seeds per day in the diet of women will alter dietary fatty acid intake or blood pressure.
- Trial name
- PSS1 (NCT01928966)
- Testing
- Pumpkin Seeds
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Texas Woman's University
Short Chain Fatty Acids Concentration in Stools, Gut Microbiota Diversity and Composition
Effects Of Dietary Fats on Gut Microbiota Composition and Metabolic Activity in Healthy Adults
This study will investigate how adding a specific type of dietary fat to daily meals for two weeks affects the gut bacteria and their activity.
- Conditions
- Short Chain Fatty Acids Concentration in Stools, Gut Microbiota Diversity and Composition, Blood Lipid Profiles, Inflammation Biomarkers
- Trial name
- NCT07550023
- Testing
- Butter, Coconut oil, Extra Virgin Olive Oil
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Muscle Strength, Cognitive Function
Fish Oil T Cell Function
The purpose of the study is to examine the effect of dietary n-3 polyunsaturated fatty acid supplementation on subjects' pan CD4+ T cell function, cognition, and muscle function.
- Trial name
- NCT02775084
- Testing
- Fish Oil, Olive Oil
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Polyunsaturated Fatty Acid (PUFA) Status
The Influence of Fish Consumption on Polyunsaturated Fatty Acid (PUFA) Status
Polyunsaturated fatty acids (PUFA) are important for health, for example for the immune system, heart health and the brain. PUFA are found in fish, nuts and oils; including these foods in the diet provides the body with PUFA.
- Trial name
- iFish (NCT03765580)
- Testing
- Fish, Control
- Where
- United Kingdom
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Anxiety, Depression
Effects of a High EPA Multinutrient Supplement on Negative Affect in Young Adults.
This is a 12-week-long, randomised, double-blind, placebo-controlled trial exploring the efficacy of a high-EPA multinutrient supplement in the management of sub-clinical anxiety and depression.
- Trial name
- NutriMOOD (NCT04844034)
- Testing
- High-EPA multinutrient supplement.
- Where
- United Kingdom
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of Roehampton
Diabetic Peripheral Neuropathy
Corneal Nerves Function and Structure
Peripheral neuropathy affects about 50% of the diabetic population and there is no treatment other than good blood glucose control, which is ineffective in subjects with type 2 diabetes.
- Trial name
- NCT04222660
- Testing
- Blackmores Omega Daily (4 1g capsules per day)
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Healthy
Screening of Healthy Adults for Genetic Variations That Control Fatty Acid Processing
The purpose of this research study is to screen healthy African American and Caucasian persons for specific differences in genes that control how fats are processed in the body.
- Trial name
- NCT01516125
- Where
- United States
- Volunteers
- 458 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Residual Disease, Aggressive Periodontitis
Omega-3 Fatty Acids Plus Low-dose Aspirin Daily Supplementation in Surgical Therapy to Treat Aggressive Periodontitis
The aim of this randomized controlled clinical trial of superiority will be to evaluate the effect of 3 g of omega-3 polyunsaturated fatty acids and 100 mg of aspirin daily supplementation over a period of 180 days as adjunct to…
- Trial name
- NCT03093207
- Testing
- Open flap debridement, Omega-3 polyunsaturated fatty acids, Aspirin
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Obesity, Overfeeding
Overeating Different Fats and Influence on Muscle Mass and Body Fat Accumulation
To investigate metabolic and molecular response to fatty acid-specific overfeeding in overweight subjects, in relation to changes in ectopic fat, lean tissue mass and insulin sensitivity
- Conditions
- Obesity, Overfeeding, Muscle Mass, Body Composition
- Trial name
- LIPOGAIN-2 (NCT02211612)
- Testing
- PUFA-group, SFA-group
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Nursing Women
Effect of n-3 Polyunsaturated Fatty Acids Supplementation on Human Milk Composition of Lactating Women
We propose to measure the LCPUFA human milk (linolenic acid, linoleic acid, docosahexaenoic acid, arachidonic acid) according to fatty acids nature and quantities consumed by lactating women
- Trial name
- Oméga 3 (NCT01288313)
- Testing
- nutritional intervention
- Where
- 4 sites in France
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Fibromyalgia, Systemic Lupus Erythematosus
Membrane Polyunsaturated Fatty Acid Content in Fibromyalgia and Systemic Lupus Erythematosus (SLE)
Polyunsaturated omega-3 fatty acids (ω3 PUFAs) are essential nutrients. Studies indicate that the incidence of Major Depression (MD) is inversely related to the consumption of fish (which are rich in ω3-PUFAs) and to the…
- Trial name
- NCT01460680
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center