Clinical trials: Polyuria
Nocturia
The Effect of Combined Systematized Behavioural Modification Education Program (SyBeMeP) With DDAVP in Patients With Nocturia
In patients with nocturia, combinational treatment of DDAVP and SyBeMeP might show better outcomes. Systemic video instruction might prove to be beneficial by helping patients have better understanding on treatment and replacing…
- Trial name
- NCT01576900
- Testing
- SyBeMeP (Systemized Behavioural Modification education Program)
- Where
- South Korea
- Volunteers
- 124 people
- Sponsor
- Seoul National University Hospital
Nocturnal Polyuria
A Cross-Functional, Population-Representative, Web-Based, Epidemiologic Study to Estimate the Prevalence and Burden of Nocturia Due to Nocturnal Polyuria in the US
To estimate the prevalence of nocturia due to nocturnal polyuria (NP) in the US and describe the demographic and clinical characteristics as well as the burden of illness in participants with nocturia due to NP.
- Trial name
- NCT04125186
- Testing
- Baseline EpiNP survey, Bladder diary, Testing of EpiNP baseline survey, bladder diary and a qualitative interview
- Where
- United States
- Volunteers
- 10,190 people
- Sponsor
- Ferring Pharmaceuticals
ADPKD
HYDROchlorothiazide to PROTECT Polycystic Kidney Disease Patients and Improve Their Quality of Life
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by progressive formation of renal cysts which ultimately lead to a loss of renal function.
- Trial name
- HYDRO-PROTECT (NCT05373264)
- Testing
- Hydrochlorothiazide 25 mg
- Where
- 25 sites in Austria, Belgium and 5 more
- Volunteers
- 300 people
- Sponsor
- University Medical Center Groningen
Obstructive Sleep Apnea
This Research Project Studies the Relationship Between OSA and Nocturia.
The main goal of the study is to explore the relationship between obstructive sleep apnoea and nocturia.
- Trial name
- NCT06239883
- Testing
- Voiding diary
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- University Hospital Ostrava
Diabetes Insipidus
Copeptin After a Subcutaneous Stimulation With Glucagon in Adults
This study is to evaluate copeptin values after the subcutaneous injection of glucagon in adults (healthy volunteers and patients with diabetes insipidus or primary polydipsia).
- Trial name
- Glucacop (NCT04550520)
- Testing
- Glucagon
- Where
- Switzerland
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Nocturia
Prevalence and Risk Factors Nocturnal Polyuria in Female OAB
Nocturnal polyuria may decrease the treatment efficacy of overactive bladder syndrome (OAB); and adjuvant medication, such as desmopressin, may be needed for the treatment of nocturnal polyuria.
- Trial name
- NCT03810027
- Testing
- Bladder diary
- Volunteers
- 1,071 people
- Sponsor
- National Taiwan University Hospital
Arginine Vasopressin Deficiency, Primary Polydipsia
Copeptin Measurement After Mannitol and Hypertonic Saline for the Diagnosis of Polyuria-polydipsia Syndrome
The aim of this study is to evaluate whether a new test using mannitol infusion can diagnose the cause of polyuria-polydipsia syndrome as accurately as the current standard test (hypertonic saline infusion) and to compare which…
- Trial name
- COMPASS (NCT07569861)
- Testing
- Mannitol, Hypertonic Saline
- Where
- Switzerland
- Volunteers
- 144 people
- Sponsor
- University Hospital, Basel, Switzerland
Parkinson Disease
Effect of Desmopressin on the Nocturnal Micturition Frequency in Patients With Parkinson Disease
This study will be conducted to study the effect of Desmopressin on the nocturnal micturition frequency in patients with idiopathic Parkinson syndrome.
- Trial name
- DEPOPA (NCT00806468)
- Testing
- Desmotabs
- Where
- Germany
- Volunteers
- 1 people
- Sponsor
- Johannes Gutenberg University Mainz
Nephrogenic Diabetes Insipidus
Pharmacologic Treatment of Congenital Nephrogenic Diabetes Insipidus
The purpose of this research study is to determine if two investigational medications will be more effective in decreasing urine output than the currently available and routinely used medications in patients with congenital…
- Trial name
- NCT00478335
- Testing
- sildenafil, calcitonin, hydrochlorothiazide/amiloride
- Where
- 2 sites in United States, Denmark
- Volunteers
- 4 people
- Sponsor
- University of Colorado, Denver
Patients Who Had the Urine Volume at Nighttime More Than One Third of Total Daily Urine Volume (NPU) and Voided More Than Two Times at Nighttime (Nocturia)
Necessity for Repetitive Education of Behavioral Modification
Few studies have reported the efficacy of repetitive education for behavioral modification as the first-line therapy for patients with nocturnal polyuria (NPU).
- Trial name
- NCT01280279
- Testing
- education for behavioral modification
- Where
- South Korea
- Volunteers
- 104 people
- Sponsor
- Seoul National University Hospital
Nocturnal Enuresis
Biomarkers in Urine for Children With Monosymptomatic Nocturnal Enuresis and Nocturnal Polyuria
The aim of the study is to identify protein markers in relation to the enuresis related nocturnal polyuria by using mass spectrometry on nocturnal urine samples.
- Trial name
- NCT04049019
- Testing
- Urine collection through a collecting device (Uridome®) for maximum 1 week, Urine collection
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Nocturia, Polyuria
Food and Salt Handling in Diuresis
Understanding the impact of food/nutrients on body fluid metabolism is important for improving diagnosis and treatment of nocturia, polyuria in relation to lifestyle interventions.
- Trial name
- NCT04526340
- Testing
- Blood sample, Bio-impedance measurement (BIA), Ingestion of testing nutrient/food capsules
- Where
- Belgium
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Lower Limb Lymphedema, Urogenital Cancer
Lymphoedema and Nocturia/ Nocturnal Polyuria After Pelvic Lymph Node Dissection for Urogenital Cancer
After the treatment of urogenital cancer, a person may develop lymphoedema of the leg(s) and/ or midline region. Lymphoedema is the result of a dysfunction in the lymphatic system and is characterized by excessive retention of…
- Trial name
- UroLymph (NCT05266157)
- Testing
- Manual lymph drainage, Usual care
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Nocturia
Trial of Desmopressin Orally Disintegrating Tablets (ODT) for Nocturia Due to Nocturnal Polyuria in Japanese Male Subjects
The purpose of this trial is to demonstrate efficacy of desmopressin ODT against placebo for the treatment of male subjects with nocturia due to nocturnal polyuria, during 12 weeks of treatment.
- Trial name
- NCT02904759
- Testing
- Desmopressin
- Where
- Japan
- Volunteers
- 342 people
- Sponsor
- Ferring Pharmaceuticals
Nocturia
Desmopressin Melt Therapy in Nocturnal Polyuria Patients: Pharmacodynamic Study
The objective of this study is to find out what the pharmacodynamic (PD) characteristics of desmopressin melt are in nocturia patients (compared to healthy volunteers and children).
- Trial name
- NCT01439997
- Testing
- Desmopressin
- Where
- Belgium
- Volunteers
- 5 people
- Sponsor
- University Hospital, Ghent
Nocturia
Bioavailability of [14C]-SK-1404 ADME & IV Microtracer Study
The primary objectives of the study are: To determine the absolute bioavailability of SK-1404 To assess the mass balance recovery after a single oral (PO) dose of carbon-14 (14C)-SK-1404 To provide plasma, urine and faecal…
- Trial name
- NCT02878096
- Testing
- [14C]-SK-1404
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Sanwa Kagaku Kenkyusho Co., Ltd.
Nocturnal Polyuria
Desmopressin Melt Therapy in Patients With Nocturnal Polyuria: a Pharmacokinetic/Dynamic Study
The objective of this study is to find out what the pharmacokinetic/dynamic (PK/PD) characteristics of desmopressin melt are in nocturia patients (compared to healthy volunteers and children).
- Trial name
- NCT01435083
- Testing
- Desmopressin
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- University Hospital, Ghent
Lower Urinary Tract Symptoms
Prevalence and Risk Factor of NP in Women With LUTS
The knowledge of prevalence and risk factors of nocturnal polyuria might be important for the treatment of women with lower urinary tract symptoms (LUTS).
- Trial name
- NCT04104100
- Volunteers
- 3,000 people
- Sponsor
- National Taiwan University Hospital
Nocturia
Desmopressin in the Treatment of Mixed Nocturia With Nocturnal Polyuria and Low Nocturnal Bladder Capacity
Nocturia is defined as waking one or more times to void during the period between going to bed with the intention of sleeping and waking with the intention of arising.The pathophysiology of nocturia is multifactorial and can be…
- Trial name
- NCT00902655
- Testing
- Desmopressin
- Where
- 6 sites in South Korea
- Volunteers
- 103 people
- Sponsor
- Samsung Medical Center
Nocturia
Trial Investigating the Long Term Safety and Tolerability of Desmopressin Orally Disintegrating Tablets (ODT) for Nocturia Due to Nocturnal Polyuria in Japanese Subjects
Demonstrate the safety and tolerability of desmopressin ODT during long-term treatment of subjects with nocturia due to nocturnal polyuria, for up to 1 year
- Trial name
- NCT03051009
- Testing
- Desmopressin ODT 25 μg, Desmopressin ODT 50 μg
- Where
- Japan
- Volunteers
- 503 people
- Sponsor
- Ferring Pharmaceuticals