Clinical trials: Poor Memory
Brain Neoplasms, Malignant, Brain Neoplasms, Benign
Pioglitazone Hydrochloride in Preventing Radiation-Induced Cognitive Dysfunction in Treating Patients With Brain Tumors
RATIONALE: Pioglitazone hydrochloride may be effective treatment for cognitive dysfunction caused by radiation therapy. PURPOSE: This phase I trial is studying the side effects and best dose of pioglitazone hydrochloride in…
- Conditions
- Brain Neoplasms, Malignant, Brain Neoplasms, Benign, Malignant Meningioma, Glioblastoma Multiforme
- Trial name
- NCT01151670
- Testing
- pioglitazone
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Wake Forest University Health Sciences
Multiple Sclerosis, Cognitive Dysfunction
HOBSCOTCH-MS-Efficacy Trial
The purpose of this study is to assess the ability of the home-based intervention, HOBSCOTCH-MS to improve the quality of life and cognitive function in Service Members, Veterans and civilians who have multiple sclerosis with…
- Conditions
- Multiple Sclerosis, Cognitive Dysfunction, Memory Disorders, Memory Impairment
- Trial name
- NCT06951919
- Testing
- Home Based Self- management and Cognitive Training Changes lives in Multiple Sclerosis (HOBSCOTCH-MS)
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Mild Cognitive Impairment, Cognitive Decline
Exercise in Adults With Mild Memory Problems
This study evaluates the effects of physical exercise on cognition, functional status, brain atrophy and blood flow, and cerebrospinal fluid biomarkers of Alzheimer's disease in adults with a mild memory impairment.
- Conditions
- Mild Cognitive Impairment, Cognitive Decline, Memory Impairment
- Trial name
- EXERT (NCT02814526)
- Testing
- Aerobic exercise, Stretching/balance/range of motion exercise
- Where
- 14 sites in United States
- Volunteers
- 296 people
- Sponsor
- Alzheimer's Disease Cooperative Study (ADCS)
Alzheimer Disease, Caregivers of Alzheimer's Disease or Memory Problem Patients
Psychological Counseling Program for Alzheimer's Patients' Caregivers
Purpose: To investigate the effects of a psychological counseling program (PsychoCP) applied to caregivers of Alzheimer's patients on perceived stress, psychological well-being and care burden.
- Conditions
- Alzheimer Disease, Caregivers of Alzheimer's Disease or Memory Problem Patients, Perceived Stress, Well-Being (Psychological Flourishing)
- Trial name
- PsychoCP (NCT06755476)
- Testing
- Psychological Counseling Program
- Volunteers
- 80 people
- Sponsor
- Aydan Akkurt Yalçıntürk
Mild Cognitive Impairment, Memory Disorders
Cognitive Training and Neuroplasticity in Mild Cognitive Impairment
The purpose of this study is to evaluate if systematic cognitive training can improve cognitive performance in participants (55 and older) with memory loss.
- Conditions
- Mild Cognitive Impairment, Memory Disorders, Memory Impairment, Cognitive Impairment
- Trial name
- CogTraining (NCT03205709)
- Testing
- Computerized Cognitive Training, Crossword Puzzles
- Where
- 2 sites in United States
- Volunteers
- 107 people
- Sponsor
- New York State Psychiatric Institute
Memory Deficits, Schizophrenia
Cognitive Enhancement on Working Memory in Patients With Schizophrenia
The investigators plan to investigate the effect of enhancement on working memory (WM) in patients of chronic schizophrenia and determine the predictive factors of effective treatment.
- Conditions
- Memory Deficits, Schizophrenia, Neurostimulator; Complications
- Trial name
- CEWMPS (NCT03872310)
- Testing
- STARSTIM
- Where
- Taiwan
- Volunteers
- 28 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Healthy, Amusia, Congenital
Auditory Deficits in Congenital Amusia (AMUSIE CONGENITALE)
The project studies auditory deficits in congenital amusia at the behavioral and neurophysiological levels. The auditory processes investigated are pitch discrimination, short-term memory, sound-induced emotions.
- Trial name
- NCT03094624
- Testing
- Neuropsychological and neurophysiological tests, Experiment 1, Experiment 2
- Where
- France
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Memory Impairment
Vilazodone for Corticosteroid-Induced Memory Impairment
The purpose of this study is to examine whether vilazodone attenuates the memory and mood effects of corticosteroids on the human hippocampus in 24 healthy controls.
- Trial name
- NCT01828515
- Testing
- Vilazodone, Hydrocortisone
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Memory Impairment
Reversing Corticosteroid Induced Memory Impairment
Medically stable outpatients receiving chronic oral corticosteroid therapy were enrolled in a 48-week randomized, double-blind, placebo-controlled, parallel-group, trial of lamotrigine.
- Trial name
- NCT01142310
- Testing
- Lamotrigine
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Texas Southwestern Medical Center
Intra Cerebral Hemorrhage, ICH - Intracerebral Hemorrhage
REpeated ASSEssment of SurvivorS in Intracerebral Hemorrhage Study
The investigators propose to perform serial detailed cognitive, motor, behavioral, and blood collection follow-up using longitudinal structured telephone interviews of an anticipated 350 ICH survivors enrolled in Minimally…
- Conditions
- Intra Cerebral Hemorrhage, ICH - Intracerebral Hemorrhage, ICH, Hemorrhage
- Trial name
- ICH03 (NCT05611918)
- Where
- 26 sites in United States
- Volunteers
- 350 people
- Sponsor
- Johns Hopkins University
ADHD
Modulation of Frontoparietal Dynamics Underlying Adolescent Working Memory Deficits
The purpose of this study is to test whether a single session of brain stimulation (called repetitive transcranial magnetic stimulation [rTMS]) can improve the brain activity underlying 'working memory.' Working memory is the…
- Trial name
- NCT05119660
- Testing
- Intermittent Theta Burst Stimulation
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bradley Hospital
Memory Deficit
Protocol Memory Deficit in Patients With Obstructive Sleep Apnea Syndrome
The main objective of this study is to evaluate the evolution of memory deficit (verbal episodic memory, procedural memory, working memory, short-term memory) in Sleep Apnea Obstructive Syndrome (SAOS) patients after treatment by…
- Trial name
- NCT00464659
- Testing
- Effective CPAP
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Grenoble
Schizophrenia, Schizoaffective Disorder
Brain Health and Exercise in Schizophrenia
To determine the effects of aerobic exercise on hippocampal volumes and severity of psychotic symptoms in a population of psychosis patients compared to healthy age/gender matched volunteers.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Poor Memory
- Trial name
- PEHP (NCT01392885)
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- BC Mental Health and Addictions Research Institute
Stroke, Gait, Unsteady
A Novel Ballet-inspired Low-impact At-home Workout Programme for Adults with Stroke
To explore the feasibility of a novel ballet-inspired low-impact at-home workout programme for community-dwelling stroke survivors in Hong Kong.
- Conditions
- Stroke, Gait, Unsteady, Balance; Distorted, Memory Impairment
- Trial name
- NCT04460794
- Testing
- Ballet-inspired workouts, Usual care
- Where
- Hong Kong
- Volunteers
- 32 people
- Sponsor
- Chinese University of Hong Kong
Dementia, Alzheimer Disease
The Healthy Patterns Sleep Study
The Healthy Patterns Study intervention is a home-based activity intervention designed to improve symptoms of circadian rhythm disorders (CRD) and quality of life (QOL) in home-dwelling persons with dementia.
- Conditions
- Dementia, Alzheimer Disease, Circadian Rhythm Disorders, Circadian Rhythm Sleep Disorder
- Trial name
- NCT03682185
- Testing
- Attention-Control Condition, Timed Activity Intervention
- Where
- United States
- Volunteers
- 421 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Traumatic Brain Injury, Insomnia
CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms
This study is a prospective two-arm, single blind randomized controlled trial design to compare the clinical effectiveness of telemedicine-delivered, 6-session, standardized cognitive behavioral therapy for insomnia (CBT-I) and…
- Conditions
- Traumatic Brain Injury, Insomnia, Depression, Post-traumatic Stress
- Trial name
- NCT05663034
- Testing
- Mindfulness-based treatment for insomnia (MBTI), Cognitive behavioral therapy for insomnia (CBT-I)
- Where
- 5 sites in United States
- Volunteers
- 360 people
- Sponsor
- Johns Hopkins University
Memory Deficits, tACS
tACS Improves Memory in Elders With Subjective Memory Complaints
Subjective memory complaints (SMC), the main cognitive component of which is event memory, is a predictor of Alzheimer's disease in elderly people.
- Trial name
- NCT05569902
- Testing
- active tACS
- Where
- Iran
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Tehran
T1DM, Sleep Disorders, Circadian Rhythm
Influence of Circadian Clock on Hormonal, Metabolic, Neurocognitive Markers in Adolescents With and Without Diabetes
Type 1 diabetes mellitus (T1DM), makes its appearance during childhood and youth, but management implications last till late adulthood.
- Conditions
- T1DM, Sleep Disorders, Circadian Rhythm, ADHD, Memory Impairment
- Trial name
- NCT04054934
- Testing
- Reversed Circadian Rhythm, Normal Circadian Rhythm
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Alzheimer Disease
Memory Impairment Study (Mild Cognitive Impairment Study)
The National Institute on Aging (NIA) is launching a nationwide treatment study targeting individuals with mild cognitive impairment (MCI), a condition characterized by a memory deficit, but not dementia.
- Trial name
- NCT00000173
- Testing
- Donepezil, Vitamin E
- Where
- 72 sites in United States, Canada
- Sponsor
- National Institute on Aging (NIA)
Alzheimer Disease
A Study to Evaluate Efficacy and Safety of Intravenous Sabirnetug in Participants With Early Alzheimer's Disease (ALTITUDE-AD)
The primary purpose of this study is to evaluate the efficacy of sabirnetug infusions administered once every four weeks (Q4W) in slowing cognitive and functional decline as compared to placebo in participants with early…
- Trial name
- ALTITUDE-AD (NCT06335173)
- Testing
- sabirnetug
- Where
- 68 sites in United States, Canada and 3 more
- Volunteers
- 542 people
- Sponsor
- Acumen Pharmaceuticals