Clinical trials: Poor Memory
Stroke (CVA) or TIA, Memory Impairment
Investigating the Efficacy of ApplTree on Prospective Memory in Stroke
After a stroke, people can experience memory problems, including difficulty remembering to do things in the future - termed "prospective memory".
- Trial name
- NCT05658315
- Testing
- ApplTree smartphone application
- Volunteers
- 6 people
- Sponsor
- NHS Greater Glasgow and Clyde
Alzheimer's Disease, Mild Cognitive Impairment
Study of Nasal Insulin to Fight Forgetfulness - Long-acting Insulin Detemir - 120 Days (SL120)
The study will examine the effects of intranasally administered long-acting insulin detemir on cognition in persons with Alzheimer's disease (AD) or amnestic mild cognitive impairment (aMCI).
- Trial name
- SL120 (NCT01595646)
- Testing
- Saline, Insulin detemir, Insulin
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- Wake Forest University Health Sciences
Providing Care for People With Memory Problems
Building Better Caregivers: Development and Evaluation
The program consists of a 6-week small-group workshop for caregivers of people with memory problems. The goal of the study is to evaluate in a one year longitudinal study, program effectiveness in reducing caregiver stress…
- Trial name
- NCT02205671
- Testing
- Building Better Caregivers Small-group Workshop
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Stanford University
Mild Cognitive Impairment
Memory Training Versus Yogic Meditation Training in Older Adults With Mild Cognitive Impairment
The purpose of this pilot study is to test whether 6 months of supervised weekly Kundalini yoga classes and a brief daily meditation homework assignment can improve memory and thinking in older adults with mild memory complaints…
- Trial name
- NCT01983930
- Testing
- Kundalini yoga and meditation, Memory Training
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- University of California, Los Angeles
HIV Positive
Thinking and Memory Problems in People With HIV
Background: People with human immunodeficiency virus (HIV) can sometimes develop thinking and memory problems. These problems can vary widely, from few symptoms to severe problems with memory and concentration.
- Trial name
- NCT01875588
- Where
- United States
- Volunteers
- 1,150 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Lyme Disease
Lyme Disease Patients With Memory Problems
The main purpose of this study is to see if a device known as Transcranial Direct Current Stimulator (tDCS) is helpful in reducing persistent symptoms after Lyme disease treatment.
- Trial name
- NCT03500770
- Testing
- Transcranial Direct Current Stimulator
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Spaulding Rehabilitation Hospital
Alzheimer Disease, Mild Cognitive Impairment
Quality Improvement and Clinical Utility PrecivityAD2(TM) Clinician Survey
There is a major unmet need for timely, non-invasive, and low-burden evaluation of patients presenting with mild cognitive impairment (MCI) and dementia.
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Dementia, Cognitive Decline
- Trial name
- QUIP II (NCT06025877)
- Testing
- PrecivityAD2(TM) blood test
- Where
- 9 sites in United States
- Volunteers
- 400 people
- Sponsor
- C2N Diagnostics
Dementia, Falls
A Study of Why People With Early Memory Problems Fall or Almost Fall
The purpose of this study is to identify the factors that are associated with falls and near falls in community-dwelling older adults with early-stage dementia.
- Conditions
- Dementia, Falls, Near-Falls
- Trial name
- NCT00434889
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Healthy
A Study in Healthy Men to Test Whether BI 409306, BI 425809 or Lamotrigine Can Reverse the Memory Problems Caused by Ketamine
The main objective of this trail is to investigate if and to what extent BI 409306, BI 425809 and lamotrigine attenuate ketamine induced cognitive deficits.
- Trial name
- NCT04602221
- Testing
- Lamotrigine, BI 409306, BI 425809
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Boehringer Ingelheim
Traumatic Brain Injury, Severe Traumatic Brain Injury
Efficacy of Pharmacological Treatment of Working Memory Impairment After Traumatic Brain Injury: Evaluation With fMRI
This study is designed to examine the effects of a wake-promoting agent (Modafinil) on working memory (WM) in persons with moderate to severe TBI utilizing a double blinded placebo controlled methodology.
- Trial name
- NCT00489892
- Testing
- Modafinil
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Kessler Foundation
Subjective Memory Impairment
Effect of Skate Skin Extract on Cognitive Function in Adults
The investigators conduct a randomized, double-blind, placebo-controlled study to investigate the effects of Skate Skin extract on cognitive function in adults with subjective memory impairment for 12 weeks.
- Trial name
- NCT03849391
- Testing
- Skate group
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Pusan National University Yangsan Hospital
COVID Long-Haul, COVID-19
Neural and Cognitive Consequences of COVID-19 Survival
The novel coronavirus SARS-CoV-2 infection, COVID, continues to rage throughout the world with 115,000,000 confirmed cases and over 2,500,000 deaths (as of Mar 3, 2021).
- Conditions
- COVID Long-Haul, COVID-19, COVID-19 Pandemic, Brain Fog
- Trial name
- NCT06208943
- Testing
- cross-sectional MRI and EEG assessments (NO INTERVENTION)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- San Francisco Veterans Affairs Medical Center
Dementia
Compassion Pilot Intervention Study to Enhanced Integrated Care for People With Severe Memory Problems
The investigators developed the theory-driven 'Compassion Intervention', an integrated, interdisciplinary approach to address existing gaps in end-of-life care for people with advanced dementia.
- Trial name
- NCT02840318
- Testing
- Compassion Intervention
- Where
- United Kingdom
- Volunteers
- 41 people
- Sponsor
- University College, London
Hypertension, Cognitive Decline
Remote Monitoring and Virtual Collaborative Care For Hypertension Control To Prevent Cognitive Decline
This purpose of this study is to examine an aggressive method of blood pressure control that involves home blood pressure monitoring and management of medications by a team of clinical pharmacists in coordination with a primary…
- Trial name
- vCCC (NCT04585880)
- Testing
- Virtual Collaborative Care Clinic
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Kansas Medical Center
Sedentary Time, Insomnia
mPATH for Low-income Older Adults
Although empirical research suggests that physical activity interventions benefit cognition and sleep in older adults in general, the possible benefit of physical activity is understudied in low-income older adults.
- Conditions
- Sedentary Time, Insomnia, Cognitive Decline
- Trial name
- NCT05935241
- Testing
- mPATH, Attention Control
- Where
- United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Memory Impairment
Age-related Longitudinal Changes in Aviator Performance
Our overall goal has been twofold: 1) to evaluate whether there are significant age-related changes in flight simulator performance near age 60, and 2) to assess whether there is an alternative model that can explain longitudinal…
- Trial name
- NCT01364753
- Where
- United States
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Stanford University
Rehabilitation, Working Memory
The Neural Substrates for Working Memory Training
This study aims to conduct a contrast study on the characteristics of functional and structural connectivity of neural networks of working memory in patients with acquired brain injury versus normal controls, using resting-state…
- Trial name
- WMT (NCT03012269)
- Testing
- Working memory training
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- China Rehabilitation Research Center
Early Memory Loss, Mild Cognitive Impairment
NAC-003 P.L.U.S. Program (Progress Through Learning Understanding & Support)
This study will be an observational study in which patients who have been prescribed CerefolinNAC® are invited to participate in surveys regarding their experiences with CerefolinNAC®.
- Conditions
- Early Memory Loss, Mild Cognitive Impairment, Alzheimer's Disease, Vascular Dementia
- Trial name
- NCT01370954
- Testing
- CerefolinNAC®
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Pamlab, Inc.
HIV-1-infection, Aging, Premature
Mental Ability Challenge Study in Adults With and Without HIV
It is estimated that by 2016, nearly 50% of HIV-positive individuals in the US will be aged 50 or older, and up to 60% of those will experience some degree of cognitive impairment as they age.
- Conditions
- HIV-1-infection, Aging, Premature, Cognitive Impairment, Memory Impairment
- Trial name
- NCT03244488
- Testing
- Scopolamine Injectable Product, Mecamylamine Pill
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Alzheimer's Disease, Mild Cognitive Impairment
Study of Nasal Insulin to Fight Forgetfulness - Short-Acting Insulin Aspart
This pilot clinical trial will examine the effects of intranasal insulin aspart on cognition, daily function, blood and cerebral spinal fluid markers of Alzheimer's disease, and amyloid deposition in the brain.
- Trial name
- SNIFF-Quick (NCT02462161)
- Testing
- Insulin aspart
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Wake Forest University Health Sciences