Clinical trials: Poor Ovarian Response
In Vitro Fertilization
Prediction of Ovarian Response
The purpose of this study is to evaluate if there is an association between the endocrine and ultrasonographic markers of ovarian reserve and the IVF outcome and to determine which markers contribute to the prediction of poor…
- Trial name
- NCT00557687
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Aristotle University Of Thessaloniki
Infertility, Poor Ovarian Response
Treatment of Poor Ovarian Responders With Corifollitropin Alfa Followed by hpHMG in a Short GnRH Agonist Protocol
The purpose of the present study is to examine the level of ovarian response and the pregnancy rates among poor ovarian responders treated with a novel treatment protocol with 150μg corifollitropin alfa followed by 300IU hMG in a…
- Trial name
- NCT01732068
- Testing
- Triptorelin, Corifollitropin alfa, hpHMG
- Where
- Belgium
- Volunteers
- 51 people
- Sponsor
- Universitair Ziekenhuis Brussel
Complications; Artificial Fertilization, Introduction of Embryo in Embryo Transfer
Growth Hormone (GH) in in Vitro Fertilization (IVF) Poor-responder Patients
Experimental study to evaluate if rGH addition to a standard controlled ovarian stimulation treatment improves ovarian response in women with previous poor ovarian response.
- Trial name
- FUNDEX001 (NCT01298960)
- Testing
- Somatropin
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Fundacion Dexeus
Infertility
Follicular Activation in Poor Responders
This study aims to assess whether activation of primordial follicles through ovarian cortex fragmentation may increase the number of antral follicles present in the ovary of patients with diminished ovarian reserve.
- Trial name
- FAPPOR (NCT02354963)
- Testing
- In vitro fragmentation of the ovarian tissue
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- César Díaz García
Poor Ovarian Reserve
Autologous Intraovarian Platelet Rich Plasma Treatment in Women With Poor Ovarian Response
Reproductive age women diagnosed with poor ovarian response (POR) based on Bologna criteria with a history of at least two prior failed ICSI cycle will be recruited for the study.
- Trial name
- NCT04797377
- Testing
- Autologous ovarian PRP injection
- Where
- Bulgaria
- Volunteers
- 66 people
- Sponsor
- Nadezhda Women's Health Hospital
Infertility
Luteal Phase Commencing of Growth Hormone
Commencing of growth hormone in luteal phase when follicular cohort for the next cycle is being gathered may increase mature oocytes in poor responder
- Trial name
- NCT00561769
- Testing
- Norditropin pen
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Gulhane School of Medicine
Subfertility, Female, Ovulation Disorder
Low Dose GnRHa Early Luteal Phase Down Regulation Versus GnRHa Ultra-short Protocol for Poor Ovarian Response
The management of the poor responder patients is very difficult. Currently, there is no any standard treatment for poor responder patients.
- Trial name
- NCT02940535
- Testing
- Diphereline (Triptorelin embonate), Decapeptyl (Triptorelin), human menopausal gonadotropin
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Navy General Hospital, Beijing
Infertility
Conversion of in Vitro Fertilization Cycles to Intrauterine Inseminations in Patients With a Poor Ovarian Response to Stimulation
The purpose of this study is to compare the efficiency of conversion to IUI and IVF in patients with a poor ovarian response to stimulation
- Trial name
- ConFIRM (NCT03362489)
- Testing
- IVF / IVF-ICSI, IUI
- Where
- 32 sites in France, Guadeloupe
- Volunteers
- 462 people
- Sponsor
- University Hospital, Angers
Poor Response to Ovulation Induction
Effect of LH Supplementation on the Endometrial Gene Expression Profile in Poor Ovarian Responders
This is a prospective randomized open-label cross-over study. Poor responder patients will undergo two ovarian stimulation cycles.
- Trial name
- NCT05405686
- Testing
- Lutropin alfa, Follitropin alfa, Endometrial biopsy
- Sponsor
- CRG UZ Brussel
Poor Ovarian Response
A Trial Study on Acupuncture Treatment of Poor Ovarian Response
The trial was completed by Shaanxi Provincial Hospital of Traditional Chinese Medicine and Northwest Women and Children's Hospital.
- Trial name
- NCT03830697
- Testing
- Acupuncture intervention
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Shaanxi Hospital of Traditional Chinese Medicine
Poor Responders
New Approach for Ovarian PRP Injection for Poor Responders
New Approach For Ovarian PRP Injection for poor responders
- Trial name
- NCT06663930
- Where
- Egypt
- Volunteers
- 21 people
- Sponsor
- Bassem Ayman Mahmoud Assaf
GH, Poor Ovarian Reserve Based on POSEIDON
To Explore the Effect of GH on Outcomes of IVF and Telomerase Activity of Granulosa Cells in Women With POR
It is still a big difficult clinical problem for patients with poor ovarian reserve undergoing in vitro fertilization. The decrease in both quality and quantity of egg are the main cause for poor clinical prognosis.
- Trial name
- NCT04384744
- Testing
- growth hormone
- Volunteers
- 40 people
- Sponsor
- Guangzhou First People's Hospital
Infertility, Female
GnRh Antagonist Protocol With Delayed Start Stimulation in Patients With Poor Ovarian Response
The main outcome measures are the number of dominant follicles (≥13 mm) on the day of hCG trigger and the number of mature (MII) oocytes collected after conventional versus delayed-start ovarian stimulation protocol.
- Trial name
- NCT03134690
- Testing
- delayed start, Conventional
- Where
- Iran
- Volunteers
- 120 people
- Sponsor
- Royan Institute
Infertility
Follicle Activation by Inhibition of the Hippo Pathway
The aim of this project is to activate recruitment and growth of resting primordial follicles in the ovaries of women with diminished ovarian reserve, in attempt to increase the chance to become pregnant, either naturally or…
- Trial name
- NCT02792569
- Testing
- Biopsy of ovarian cortical tissue
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Anders Nyboe Andersen
Poor Ovarian Response
A Randomized Controlled Study of Different Trigger Modes of Antagonist Regimen in Patients With Low Ovarian Reserve
Assisted reproductive technology (ART), especially controlled ovarian stimulation (COS), significantly increased clinical pregnancy rates among infertile patients.
- Trial name
- NCT04717752
- Testing
- Ovidrel, Troprilin
- Where
- China
- Volunteers
- 310 people
- Sponsor
- Nanjing University
Female Infertility Due to Diminished Ovarian Reserve
Microflare Protocol in Poor Responders
The effect of use of the microflare down regulation protocol on the outcome of the IVF/ICSI cycles in poor responders
- Trial name
- NCT02185326
- Testing
- Growth hormone (Norditropin, Novo nordisk)
- Where
- Egypt
- Volunteers
- 145 people
- Sponsor
- Woman's Health University Hospital, Egypt
Poor Ovarian Response
Ovarian PRP Injection in Women With POR
Patients with poor ovarian response (POR）is considered one of most challenging tasks in artificial reproductive treatment (ART).
- Trial name
- NCT05601193
- Testing
- autologous platelet-rich plasma
- Where
- China
- Volunteers
- 390 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Poor Ovarian Response
Effect of Recombinant Human Growth Hormone Injection on the Clinical Outcome of POR in Patients Undergoing IVF/ET
Observe the clinical efficacy and safety of Recombinant Human Growth Hormone Injection assisted in the treatment of the patients with poor ovarian response in vitro fertilization and embryo transfer.
- Trial name
- NCT02801591
- Testing
- Conventional ovarian stimulation proctol without rhGH
- Where
- 2 sites in China
- Volunteers
- 240 people
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Women With Poor Ovarian Response
GnRH Agonist Triggering Supplemented With Hcg in Women With Poor Ovarian Response
During the last decades, owing to the growing tendency of women to delay childbearing plans because of career and personal priorities, fertility specialists today are seeing more and more women with poor ovarian reserve and with…
- Trial name
- NCT02144818
- Testing
- Ovitrel, Decapeptyl
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Ovarian Response
The Effects of Coenzyme Q10 Pretreatment on Ovarian Function and Assisted Reproductive Outcomes in Patients With Ovarian Hyporesponsiveness.
This prospective, randomized, double-blind, controlled study will be conducted at Tangdu Hospital, Air Force Medical University. It plans to enroll 128 patients with poor ovarian response for a 2-year study.
- Trial name
- NCT07260773
- Testing
- Coenzyme Q10
- Volunteers
- 128 people
- Sponsor
- Tang-Du Hospital