Clinical trials: Population Medicine
Diabetes Mellitus, Type 2
A Study Comparing SHR-3167 With Insulin Degludec in Adults With Type 2 Diabetes Currently Treated With Basal Insulin
The purpose of this study is to evaluate efficacy and safety of once-weekly SHR-3167 and once-daily Insulin Degludec in participants with Type 2 diabetes that has been treated with basal insulin.
- Trial name
- NCT07913061
- Testing
- SHR-3167, insulin degludec
- Where
- 2 sites in China
- Volunteers
- 680 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Tardive Dyskinesia, Schizophrenia
Extract of Ginkgo Biloba and Tardive Dyskinesia
The purpose of this study is to determine whether Extract of Ginkgo Biloba is effective in the treatment on Tardive dyskinesia
- Trial name
- EGBTD (NCT00672373)
- Testing
- Extract of Ginkgo Biloba (EGb-761 capsules)
- Where
- China
- Volunteers
- 157 people
- Sponsor
- Beijing HuiLongGuan Hospital
Type 2 Diabetes Mellitus
Phase 2 Study To Evaluate Safety And Efficacy Of Investigational Drug - PF04937319 In Patients With Type 2 Diabetes
B1621007 is designed to study the safety and efficacy of PF-04937319 in patients with type 2 diabetes
- Trial name
- NCT01475461
- Testing
- PF-04937319 - 3mg, PF-04937319 - 20mg, PF-04937319 - 50mg
- Where
- 63 sites in United States, Hungary and 6 more
- Volunteers
- 345 people
- Sponsor
- Pfizer
Cancer
Mindfulness-Based Art Therapy for Cancer Patients
The purpose of this study is to determine whether cancer patients who receive the mindfulness-based art therapy (MBAT) program demonstrate improvement in health-related quality of life, a reduction in stress-related symptoms, and…
- Trial name
- NCT00034970
- Testing
- Mindfulness-based at therapy
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Sarcopenia
A 24-week Off-drug Extension Study in Sarcopenic Elderly Who Completed Treatment in the 6-month Core Study
This extension study was a 24-week off-drug follow-up of the core CBYM338E2202 (NCT ) study and the main objective was to determine the long-term durability of bimagrumab (BYM338) effect after a 6-month treatment period.
- Trial name
- NCT02468674
- Testing
- bimagrumab
- Where
- 30 sites in United States, Australia and 10 more
- Volunteers
- 160 people
- Sponsor
- Novartis Pharmaceuticals
Type 2 Diabetes Mellitus
A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus
The purpose of this study is to evaluate the efficacy, safety, and tolerability of elecoglipron compared with oral semaglutide in adults with T2DM and increased cardiovascular risk that is inadequately managed alone or on stable…
- Trial name
- Eluminate-2 (NCT07662213)
- Testing
- Elecoglipron, Semaglutide
- Where
- 210 sites in United States, Argentina and 13 more
- Volunteers
- 1,200 people
- Sponsor
- AstraZeneca
Schizophrenia
Adjunctive SPD489 to Antipsychotic Medication in Clinically Stable Adults With Persistent Predominant Negative Symptoms of Schizophrenia
The primary purpose of this study is to determine whether SPD489 40 mg, 100 mg, and 160 mg are effective and safe in the treatment of Negative Symptoms of Schizophrenia (NSS).
- Trial name
- NCT01738698
- Testing
- SPD489 40mg, SPD489 100mg, SPD489 160mg
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Shire
Chronic Disease
A Population-based Cohort in Northern Spain
Cantabria Cohort stems from a research and action initiative lead by researchers from Valdecilla Research Institute (IDIVAL), Marqués de Valdecilla University Hospital and University of Cantabria, supported by the regional…
- Trial name
- COHORTE (NCT05852678)
- Testing
- cohort
- Where
- Spain
- Volunteers
- 22,000 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Marqués de Valdecilla
HIV Infections
Strategies to Improve the HIV Care Continuum Among Key Populations in India
This clinical trial will compare the effectiveness of integrated care centers vs. integrated care centers plus HIV patient treatment incentives for achieving HIV treatment targets among people who inject drugs and men who have…
- Trial name
- NCT02969915
- Testing
- Incentives, Integrated Care Centers
- Where
- India
- Volunteers
- 2,314 people
- Sponsor
- Johns Hopkins University
Diabetes Mellitus, Type 2
Out-Patient Study in Patients With Type 2 Diabetes Mellitus Who Are Taking no Diabetes Medication or Metformin Only
This study is a placebo-controlled study in patients with Type 2 Diabetes Mellitus who are either taking no diabetes medication or who are taking metformin only.
- Trial name
- NCT00518115
- Testing
- Albiglutide (GSK716155) or exenatide
- Where
- 163 sites in United States, Chile and 1 more
- Volunteers
- 361 people
- Sponsor
- GlaxoSmithKline
Psoriatic Arthritis
Efficacy and Safety Study of Apremilast to Treat Active Psoriatic Arthritis (PsA)
The purpose of this study is to determine whether apremilast is safe and effective in the treatment of patients with psoriatic arthritis who have not been previously treated with DMARDs.
- Trial name
- PALACE4 (NCT01307423)
- Testing
- Apremilast 20mg, Apremilast 30mg
- Where
- 118 sites in United States, Australia and 16 more
- Volunteers
- 529 people
- Sponsor
- Amgen
Hereditary Cancer Syndromes
Increasing Uptake of Cascade Testing in Families With Familial Cancer Syndromes: A Randomized Controlled Trial of a Registry-aided Model.
The purpose of this study is to compare the uptake rates of a patient-initiated model of cascade testing with a registry-aided model amongst relatives of patients identified to have a particular cancer predisposition gene.
- Trial name
- NCT07626814
- Testing
- Proband-dependent approach, Combination of the proband-dependent approach with additional registry-aided testing reminders
- Where
- Singapore
- Volunteers
- 545 people, healthy volunteers welcome
- Sponsor
- National Cancer Centre, Singapore
Hypertension, Primary Hypertension
Effectiveness of SMS Reminders of Blood Pressure-lowering Drugs Intake
By conducting the SPPA trial we try to find out, whether personalized Short Message Service (SMS) reminders of blood pressure-lowering medication can effectively increase patients' adherence to blood pressure-lowering medication.
- Conditions
- Hypertension, Primary Hypertension, Non-Adherence, Medication, Non-Adherence, Patient
- Trial name
- SPPA (NCT03105687)
- Testing
- SMS reminders of medicines intake
- Where
- 24 sites in Slovakia
- Volunteers
- 300 people
- Sponsor
- Comenius University
Epilepsy, Tonic-Clonic
Study Evaluating LAMICTAL Extended-Release Therapy Added To Current Seizure Treatments In Patients With Primary Generalized Tonic-Clonic Seizures (PGTC) Seizures
This study is being conducted to compare the efficacy and safety of LAMICTAL (lamotrigine) extended-release with placebo in the treatment of Primary Generalized Tonic-Clonic (PGTC) seizures.
- Trial name
- NCT00104416
- Testing
- lamotrigine (LAMICTAL) extended-release
- Where
- 146 sites in United States, Argentina and 9 more
- Volunteers
- 153 people
- Sponsor
- GlaxoSmithKline
Coronary Artery Disease, Myocardial Ischemia
BIOFLOW III Asia Registry Orsiro Stent System
Cliflical evaluation of th' Orsiro LESS 10 diabetic subjects requiring coronary revasculariza t ion with Drug Eluting Stefl ts (DES) .880 subjects will be enrolled in this registry.
- Conditions
- Coronary Artery Disease, Myocardial Ischemia, Diabetes Mellitus Type 1 or 2
- Trial name
- NCT01941290
- Where
- 19 sites in China, India and 3 more
- Volunteers
- 387 people
- Sponsor
- BIOTRONIK Asia Pacific Pte Ltd
Rheumatoid Arthritis
Evaluation of Effectiveness of Two Dosing Regimens of Fostamatinib Compared to Placebo in Patients With Rheumatoid Arthritis (RA) Who Are Taking Disease Modifying Anti-rheumatic Drug (DMARD) But Not Responding.
The purpose of the study is to evaluate the effectiveness of two dosing regimens of fostamatinib compared to placebo, in patients with rheumatoid arthritis (RA) who are taking disease modifying anti-rheumatic drug (DMARD) but not…
- Trial name
- OSKIRA - 2 (NCT01197534)
- Testing
- fostamatinib
- Where
- 149 sites in United States, Canada and 14 more
- Volunteers
- 913 people
- Sponsor
- AstraZeneca
Aging, Age Problem
Technologies for Participatory Medicine and Health Promotion in the Elderly Population
Introduction: The progressive aging of the population is a socio-demographic phenomenon experienced by most countries in the world in recent decades, especially in Japan and in many European Union countries.
- Trial name
- GERIATIC (NCT03504813)
- Testing
- Physical activities program, Relaxation training, Training of the pelvic floor
- Where
- Spain
- Volunteers
- 57 people
- Sponsor
- Universidade da Coruña
Rheumatoid Arthritis
Efficacy Confirmation Trial of CDP870 as add-on Medication to Methotrexate (MTX) in Japanese Rheumatoid Arthritis (RA)
The objective of this trial is to investigate the efficacy (American College of Rheumatology 20% : ACR20) superiority of two dose regiments of CDP870 versus placebo in combination with MTX in active RA patients who have an…
- Trial name
- NCT00791999
- Testing
- CDP870 400mg, CDP870 200mg, CDP870 100mg
- Where
- 8 sites in Japan
- Volunteers
- 316 people
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Glaucoma, Eye Diseases
KJ-TFC-004 Drug-drug Interaction Study
To assess the pharmacokinetic Interaction between Dorzolamide and Brimonidine in healthy male subjects.
- Conditions
- Glaucoma, Eye Diseases, Ocular Hypertension
- Trial name
- NCT02967614
- Testing
- [A], [B], [A]+[B](1)
- Where
- South Korea
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Kukje Pharma
Cervical Pain
Effect of Group Pilates and Yoga Exercise Classes for Chronic Cervical Pain
Exercise has been found to be effective in alleviating back and neck pain. Two exercise methods which are available in the community in a group format are Yoga and Pilates.
- Trial name
- Pilates/Yoga (NCT01999283)
- Testing
- Yoga Group Exercise, Pilates Group Mat Exercise
- Where
- 4 sites in United States
- Volunteers
- 88 people
- Sponsor
- Wayne State University
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