Clinical trials: Population Study
Anxiety, Stress
The Moving 2 Mindful (M2M) Study: Mindfulness Group + Ecological Momentary Intervention
This study will evaluate the feasibility and acceptability of Learning to BREATHE (a mindfulness intervention for adolescents) plus an ecological momentary intervention (Learning to Breathe Plus), and will examine the extent to…
- Trial name
- M2M (NCT03869749)
- Testing
- Learning to BREATHE Plus, Health and wellness
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Covid19 Vaccine
A Study to Evaluate Immunogenicity and Safety of MVC-COV1901 Compared With AZD1222 Against COVID-19 in Adults
The purpose of this study is to assess the immunogenicity and safety of MVC-COV1901 vaccine compared to AZD1222 in heathy adults.
- Trial name
- NCT05011526
- Testing
- MVC-COV1901, AZD1222
- Where
- 2 sites in Paraguay
- Volunteers
- 1,030 people, healthy volunteers welcome
- Sponsor
- Medigen Vaccine Biologics Corp.
Idiopathic Pulmonary Fibrosis
A Study to Evaluate the Safety, Tolerability and Blood Levels of GSK3915393 Administered to Healthy Participants of Chinese, Japanese and European Ancestry and to Assess Effects of GSK3915393 on Nintedanib
GSK3915393 is a new medicine which is being developed for a chronic lung disease called Idiopathic Pulmonary Fibrosis (IPF). This is a healthy participant study which has two parts.
- Trial name
- NCT06625489
- Testing
- Nintedanib, GSK3915393
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Hypertension
Study to Evaluate the Pharmacokinetics of CIN-107 in Subjects With Varying Degrees of Renal Function
This is a Phase 1, open-label, parallel-group study in subjects with varying degrees of renal function to assess the safety, tolerability, and Pharmacokinetics of a single 10 mg oral dose of CIN-107.
- Trial name
- NCT05470725
- Testing
- CIN-107
- Where
- 2 sites in United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Cardiorespiratory Fitness, Eye Disorders
Ralation Between Cardiorespiratory Fitness and Mean Corrected Intraocular Pressure
Objective: To investigate the association between cardiorespiratory fitness and mean corrected intraocular pressure (IOP) in a normotensive health check-up population, and to evaluate potential differences across age and sex…
- Trial name
- NCT07676747
- Testing
- Mean corrected intraocular pressure (IOP) of both eyes
- Where
- China
- Volunteers
- 2,921 people, healthy volunteers welcome
- Sponsor
- Sichuan Academy of Medical Sciences
Healthy
A Study in Healthy People to Measure the Amount of BI 655130 in the Blood After Injecting Different Doses Into Different Parts of the Body
The primary objective of this trial is to investigate the relative bioavailability of BI 655130 administered as two subcutaneous injections in the left and right periumbilical region compared to a single subcutaneous…
- Trial name
- NCT03617835
- Testing
- R - Low dose of BI 655130, T1 - Low dose of BI 655130, T2 - Low dose of BI 655130
- Where
- Belgium
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Streptococcus Group A
GAS Epi Study to Measure Age-Related Antibody Titers to J8 Vaccine
The purpose of this ongoing study (Part V) is to evaluate the cause, distribution, control, and results of group A streptococcus infections (GAS) in Fiji.
- Trial name
- NCT00264784
- Where
- Fiji
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Safety Issues
Protectivity and Safety of Quadrivalent Influenza HA Vaccine in Indonesian Population
This study is to assess protectivity and safety of Quadrivalent Influenza Vaccine in Indonesian Population
- Trial name
- NCT03336593
- Testing
- Quadrivalent Influenza Vaccine, Trivalent Influenza Vaccine
- Where
- 3 sites in Indonesia
- Volunteers
- 810 people, healthy volunteers welcome
- Sponsor
- PT Bio Farma
Healthy
Study to Assess Safety, Tolerability and Pharmacokinetics After Single Dose of AZD2516 to Japanese Healthy Subjects
The primary purpose of this study is to assess the safety and tolerability of AZD2516 following administration of a single dose to Japanese healthy subjects.
- Trial name
- NCT00972049
- Testing
- AZD2516
- Where
- Japan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Asthma, Chronic Obstructive Pulmonary Disease (COPD)
Lungs on Fire: Wildfire Smoke, Incident Diseases, Susceptible Populations, and Community Values in Canada
Wildfire smoke (WFS) is the leading climate-related risk in Canada and the main source of harmful air pollution. While short-term breathing problems caused by smoke are well known, there is limited knowledge on how repeated…
- Conditions
- Asthma, Chronic Obstructive Pulmonary Disease (COPD), Lung Cancer
- Trial name
- LoF (NCT07536178)
- Testing
- Woodsmoke (Lodgepole Pine) exposure, Filtered air exposure
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Leiomyoma
Study in Healthy Tubal Ligated Women to Evaluate Pharmacodynamics, Safety and Pharmacokinetics of BAY1002670
Effects of BAY1002670 on bleeding pattern: non-bleeding rate; on endometrium; on ovarian function; return of menstrual bleeding after treatment; safety and tolerability; PK/PD (pharmacokinetic/pharmacodynamic) relationship
- Trial name
- NCT01816815
- Testing
- BAY1002670
- Where
- 6 sites in Belgium, Germany and 1 more
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Bayer
Influenza
A Study of Exclusion Criteria in a University Population
Much of community transmission of seasonal and pandemic influenza occurs in younger individuals, because of their susceptibility and their social interaction patterns.Universities are places where transmission of influenza is…
- Trial name
- eX-FLU (NCT01472536)
- Testing
- Sequestration
- Where
- United States
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Hepatic Impairment
Safety and Pharmacokinetics/Pharmacodynamics of SHR3824 in Patients With Hepatic Impairment
Comparison of the pharmacokinetics/Pharmacodynamics of the SHR3824 in Patients With Mild, Moderate and Severe Hepatic Impairment Compared with Healthy Volunteers.
- Trial name
- NCT03160014
- Testing
- SHR3824
- Where
- China
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Insulin Resistance, Type 2 Diabetes Mellitus with Features of Insulin Resistance
NUTRITIONAL INTERVENTION STUDY to EVALUATE the EFFECT of ACHETA DOMESTICUS POWDER CONSUMPTION on GLUCOSE HOMEOSTASIS and INTESTINAL DYSBIOSIS in HEALTHY and PREDIABETIC POPULATION.
A nutritional intervention study is proposed to evaluate the association between the consumption of A. domesticus (insect protein) powder and the effect on insulin resistance and the microbiome, in order to generate personalized…
- Trial name
- DIBAN (NCT06622616)
- Testing
- EVALUATE THE EFFECT OF ACHETA DOMESTICUS POWDER CONSUMPTION ON GLUCOSE HOMEOSTASIS AND INTESTINAL DYSBIOSIS
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- María Isabel Espinosa
Healthy
A Pharmacokinetic Study of CVX-096 (PF-04856883) in Healthy Volunteers
The purpose of the study is to further evaluate the PK characteristics of PF-04856883.
- Trial name
- NCT01637285
- Testing
- PF-04856883
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Pfizer
Obesity
Safety and Efficacy of APD356 in the Treatment of Obesity
This is a research study of an investigational drug, APD356, a novel, selective 5-HT2c receptor agonist, in clinical development as a potential treatment for obesity.
- Trial name
- NCT00104507
- Testing
- APD356
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Eisai Inc.
Acne Vulgaris
Double-blind Placebo-controlled Trial of Generic Clindamycin/Benzoyl Peroxide Gel Versus Onexton Gel in Acne Vulgaris
Actavis has developed a generic formulation of clindamycin 1.2% and benzoyl peroxide 3.75% gel. This study is designed to evaluate the safety and efficacy of this formulation in subjects with Acne Vulgaris
- Trial name
- NCT02616614
- Testing
- Onexton, Clindamycin/benzoyl peroxide gel
- Where
- 17 sites in United States
- Volunteers
- 862 people, healthy volunteers welcome
- Sponsor
- Actavis Inc.
Respiratory Disease
Luftibus in the School: a Study on the Respiratory Health of Schoolchildren.
This study assessed the respiratory health of schoolchildren from the canton of Zurich by combining self-reported information on respiratory symptoms with lung function test results and air pollution measurements.
- Trial name
- LUIS (NCT03659838)
- Where
- Switzerland
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Healthy
A Safety and Pharmacokinetic Study Between HLX02 and Herceptin®(U.S. and German Sourced) in Healthy Chinese Male Subjects
Assessment of safety of HLX02 at different doses. Randomised, double-blind, parallel group Phase I study to compare PK profiles and to assess the safety and immunogenicity between HLX02 and Herceptin® (U.S. and German).
- Trial name
- NCT02581748
- Testing
- HLX02, Herceptin
- Where
- China
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Shanghai Henlius Biotech
Clinical Trial, Phase I
Study in Healthy Young Women to Investigate the Pharmacodynamics, Pharmacokinetics and Safety of Vilaprisan
This is a study in healthy women of reproductive age to investigate the pharmacodynamics (mainly ovarian activity), pharmacokinetics and safety of vilaprisan after daily oral administration of 4 different doses over 84 days…
- Trial name
- NCT02262663
- Testing
- Vilaprisan (BAY1002670)
- Where
- 2 sites in Germany
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bayer
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