Clinical trials: Population Study
Cancer Diagnosis
Evaluation of Multi-Cancer Early Detection Testing in a High-Risk Military Population: The Sentinel Study
The purpose of this research study is to evaluate the possible benefits of an investigational, but commercially available Galleri multi-cancer early detection (MCED) blood test which is designed to detect many types of cancer…
- Trial name
- NCT06523868
- Testing
- GRAIL Galleri
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Healthy
Multiple Oral Doses Of PH-797804 In Healthy Japanese Adult Subjects
Study A6631027 will evaluate the safety, tolerability and pharmacokinetics of PH-797804 when administered to healthy Japanese subjects once a day (QD) for 10 days.
- Trial name
- NCT01217918
- Testing
- 1 mg, 5 mg, 10 mg
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pfizer
Covid19
KBP-201 COVID-19 Vaccine Trial in Healthy Volunteers
This is an First In Human (FIH), observer-blinded, randomized, placebo-controlled, parallel group study to evaluate the safety and immunogenicity of KBP-COVID-19 plus CPG adjuvant vaccine in healthy adult subjects in 2 age…
- Trial name
- NCT04473690
- Testing
- Low Dose of KBP-COVID-19, High Dose of KBP-COVID-19
- Where
- 8 sites in United States, Canada
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- KBio Inc
Abnormal Labial Frenum Frenectomy, Frenectomy
Pain After Diode Laser Frenectomy in Children
This prospective single-group clinical study aims to evaluate postoperative pain following diode laser-assisted frenectomy in pediatric patients and to assess the agreement between different pediatric pain assessment scales.
- Trial name
- PED-FREN (NCT07706023)
- Testing
- Diode Laser-Assisted Frenectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Healthy
A Clinical Study Evaluating The Safety And Tolerability Of PF-04427429 In Healthy Adult Volunteers. The Pharmacokinetics And Pharmacodynamics Of PF-04427429 Will Also Be Investigated
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of PF-04472429 administered intravenously to healthy adult volunteers.
- Trial name
- NCT01165723
- Testing
- PF-04427429
- Where
- Belgium
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Pfizer
Type 2 Diabetes
Family Health Team High-Intensity Interval Training
With the rapid shift to virtual care, this pilot study aims to determine the feasibility of prescribing low-duration, interval-based training through virtual care.
- Trial name
- FHT HIIT (NCT04109235)
- Testing
- High-Intensity Interval Training Physical Activity (PA) Advice, Population-Based Physical Activity (PA) Advice
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Infraorbital Hollowing
A Study to Evaluate the Safety and Effectiveness of Injectable Gel for Correction of Infraorbital Hollowing in Chinese Population
A Multicenter, Evaluator-blinded, Randomized, No-treatment Controlled Study to Evaluate the Safety and Effectiveness of MAILI PRECISE With Lidocaine Injectable Gel for Correction of Infraorbital Hollowing in Chinese Population
- Trial name
- NCT06394076
- Testing
- Cross-linked sodium hyaluronate gel for injection containing lidocaine
- Where
- China
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Sinclair Pharmaceuticals Limited
Prediabetes
Effects of Blueberry Dry Powder on Glycemic Status in Subjects With Prediabetes
The purpose of the present study is to evaluate the effect of blueberry dry powder on glycemic status (fasting plasma glucose, 2h glucose concentration after the oral glucose tolerance test (OGTT), or HbA1c) in subjects with…
- Trial name
- NCT02023320
- Testing
- Low dose of blueberry dry powder, High dose of blueberry dry powder
- Where
- Japan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hiroshima University
NAFLD, Nonalcoholic Fatty Liver Disease
An Investigational Study to Evaluate Experimental Medication BMS-986036 in Participants With Different Levels of Kidney Function
This is an investigational study to evaluate the experimental medication BMS-986036 in participants with different levels of kidney function.
- Conditions
- NAFLD, Nonalcoholic Fatty Liver Disease, Nonalcoholic Steatohepatitis
- Trial name
- NCT03674476
- Testing
- BMS-986036
- Where
- 4 sites in Czechia, Hungary
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Severe Hepatic Impairment
An Open-Label, Single-Dose, Parallel-Group Study of the Pharmacokinetics and Safety of EQ143
Participants aged 18 to 75 years with severe hepatic impairment (Child-Pugh class C) who meet the full study eligibility criteria will be enrolled into the study.
- Trial name
- NCT05199610
- Testing
- aumolertinib
- Where
- 3 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- EQRx International, Inc.
Healthy
A Study of Single and Multiple Ascending Doses of TC-5214 in Japanese Healthy Elderly Male and Female Volunteers
The purpose of this study is to assess safety, tolerability and pharmacokinetics of TC-5214 in elderly healthy Japanese volunteers.
- Trial name
- NCT01392820
- Testing
- TC-5214
- Where
- Japan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
HIV (Human Immunodeficiency Virus)
Multimorbidity and Polypharmacy in People With HIV vs. the General Population in the Basque Country
People living with HIV now have a life expectancy similar to that of the general population, thanks to major advances in antiretroviral treatment.
- Trial name
- NCT07621224
- Testing
- No intervention
- Volunteers
- 12,546 people, healthy volunteers welcome
- Sponsor
- Biogipuzkoa Health Research Institute
Low Mood, Depressive Symptoms
The Effects of Bifidobacterium Longum 1714® in a Population With Low Mood
A randomised, double-blind, placebo-controlled clinical trial to evaluate the effect of 8 weeks of supplementation with Bifidobacterium longum 1714® strain on Beck's Depression Inventory-II Score in adults who experience low mood.
- Trial name
- NCT04925440
- Testing
- Bifidobacterium longum 1714® strain
- Where
- Ireland
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- PrecisionBiotics Group Ltd.
Coronary Syndrome, Acute, Coronary Artery Disease
A Study of Population and Sex-specific Troponin Cutoffs for Ruling Out Acute Myocardial Infarction
Acute myocardial infarction (MI) is defined as a rise and/or fall in cardiac troponins (cTn) with at least one value above the 99th percentile upper reference limit (URL) in the context of symptoms or clinical evidence of…
- Conditions
- Coronary Syndrome, Acute, Coronary Artery Disease, Myocardial Infarction
- Trial name
- DANSPOT (NCT05336435)
- Testing
- Implementation of the new population and sex-specific 99th percentile URL for cardiac troponin
- Where
- 22 sites in Denmark
- Volunteers
- 5,175 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Alzheimer Disease, Dementia
Cognitive Impairment Cohort Study of the Elderly Population in SheMountain
This study is a prospective observational study, which involves a cohort of 2000 all-sex and all-ethnic people aged 60 years and above with permanent residence in Tianma area, SheMountain Town, Songjiang District (suburban area)…
- Conditions
- Alzheimer Disease, Dementia, Neurodegenerative Diseases, Cognitive Impairment
- Trial name
- SheMountain (NCT05667935)
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Hypertension
Phase 1 PK Study to Evaluate the PK of CIN-107 in Subjects With Hepatic Impairment
The goal of this Phase 1, open-label, single-dose, parallel-group study is to evaluate the pharmacokinetics (PK) of a single 10-mg oral dose of baxdrostat in subjects with varying degrees of hepatic function.
- Trial name
- NCT05961397
- Testing
- baxdrostat
- Where
- 5 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy Volunteers
A Study to Evaluate the Pharmacokinetics of Dexlansoprazole 30 Milligram (mg) and 60 mg Delayed-release Capsules in Healthy Chinese Participants
The purpose of this study is to assess the pharmacokinetics after a single dose of dexlansoprazole 30 and 60 mg delayed-release capsules in healthy Chinese participants.
- Trial name
- NCT03316976
- Testing
- Dexlansoprazole
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Takeda
Acne
Efficacy Study of Cosmetic Product RV3278AET0943 Versus Non-treated Group in Adults With Oily and Acne Prone Skin
The aim of this study is to evaluate, at different times, the RV3278A - ET0943 cosmetic product efficacy after 8 weeks of application on the face (twice-daily application).
- Trial name
- NCT04873089
- Testing
- Cosmetic product
- Where
- France
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Pierre Fabre Dermo Cosmetique
Rabies, Healthy Volunteers
Study of Purified Vero Rabies Vaccine Compared With Two Reference Rabies Vaccines, Given in a Pre-exposure Regimen to Children and Adults and as Single Booster Dose to a Subset of Adults
The primary objective of this study is: To demonstrate the VRVg-2 is non-inferior to Verorab and Imovax Rabies vaccines in each age group (pediatric and adult populations) when administered as a 3-dose PrEP regimen, in terms of…
- Trial name
- VRV12 (NCT04127786)
- Testing
- Purified vero rabies vaccine - serum free - VRVg-2, Purified inactivated rabies vaccine - Verorab®, Purified inactivated rabies vaccine - Imovax® Rabies
- Where
- 4 sites in Thailand
- Volunteers
- 1,708 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
COVID-19
Safety, Tolerability and Immunogenicity of Recombinant COVID-19 Vaccine Betuvax-CoV-2
Randomized, double-blind, multicenter parallel-group clinical study of safety, tolerability and immunogenicity of the Betuvax-CoV-2 vaccine.
- Trial name
- Betuvax-CoV2 (NCT05270954)
- Testing
- Betuvax-CoV-2
- Where
- 3 sites in Russia
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Artgen Biotech
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