Clinical trials: Port Wine Stain
Infantile Hemangioma, Very Low Birth Weight Infants
Timolol for the Prevention of Proliferation of Infantile Hemangioma (TiPPIH Trial)
The purpose of this trial is to see if a topical beta blocker is effective in preventing the proliferation of infantile hemangioma.
- Trial name
- TiPPIH (NCT01434849)
- Testing
- topical 0.5% Timolol maleate
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Alice K. Gong
Infantile Hemangioma
Efficacy and Safety of Different Initial Doses of Oral Propranolol in the Treatment of Ulcerated Infantile Hemangioma
The main objective of this study was to determine the efficacy of different doses of propranolol in the treatment of ulcerattion infantile hemangioma (IH).
- Trial name
- NCT06798363
- Testing
- propranolol
- Where
- 3 sites in China
- Volunteers
- 32 people
- Sponsor
- West China Hospital
Hemangioma
A Study of CCCTC-binding Factor (CTCF) in Infantile Hemangiomas
The purpose of this study is to evaluate the genotype of CTCF, a proven transcription factor, in patients with infantile hemangiomas and to monitor tumor growth.
- Trial name
- NCT00974129
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yale University
Comparison of Efficacy of Sclerotherapy in Infantile Hemangioma
Efficacy of Intralesional Bleomycin Alone and in Combination With Dexamethasone in Infantile Haemangiomas
Objective: This study is intended to compare the outcome of intralesional bleomycin with dexamethasone versus the bleomycin alone in infantile haemangioma.
- Trial name
- hemangioma (NCT06080724)
- Testing
- Comparison of intralesional injection of bleomycin alone and combined with injection dexamethasone
- Where
- Pakistan
- Volunteers
- 114 people
- Sponsor
- King Edward Medical University
Infantile Hemangioma
Nadolol Versus Propranolol in Children With Infantile Hemangiomas
The purpose of this study is to assess the efficacy and safety of oral propranolol versus nadolol in patients with Infantile Hemangiomas (IH) in a randomized, controlled, double-blinded study.
- Trial name
- NCT02505971
- Testing
- Nadolol, Propranolol
- Where
- Canada
- Volunteers
- 74 people
- Sponsor
- The Hospital for Sick Children
Port-wine Stain
Evaluate the Port-wine Stain Birthmark Treatment Before and After Pulsed Dye Laser Treatment
Port-wine stain is a congenital, progressive vascular malformation of human skin involving post-capillary venules that occurs in an estimated 0.3% of children and can alter personality development and psychological in children.
- Trial name
- NCT01774552
- Testing
- Photo Acoustic Microscopy and Optical Coherence tomography
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Hemangioma, Vascular Anomalies
Genetic Basis of Hemangiomas
The purpose of this study is to determine if there are genes that are common in children with infantile hemangioma. This information will allow physicians to improve care for patients who have been diagnosed with this disease and…
- Trial name
- NCT00466375
- Testing
- Cheek cell samples or blood sample (4mL), Cheek cell sample or blood sample (4mL)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Medical College of Wisconsin
Hemangioblastomas, Von Hippel Lindau Disease
Bevacizumab (Avastin) in Unresectable/Recurrent Hemangioblastoma From Von-Hippel-Lindau Disease
Von Hippel-Lindau (VHL) disease is an inherited syndrome manifested by a variety of benign and malignant tumors. Hemangioblastomas are the most common lesion associated with VHL disease affecting 60-84% of patients with a mean…
- Trial name
- NCT01015300
- Testing
- Avastin
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Infantile Hemangioma
Nadolol for Proliferating Infantile Hemangiomas
The purpose of this study is to explore the efficacy and safety of Nadolol in hemangiomas of infancy. The secondary objective is to assess the feasibility of conducting a randomized controlled trial comparing nadolol with…
- Trial name
- NCT01010308
- Testing
- Nadolol
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- The Hospital for Sick Children
Vascular Lesion
Treatment of Vascular Lesions With a Tandem 532/1064 nm Laser
Dermatologists have for many years treated vascular lesions by a variety of modalities including cryosurgery, electrotherapy, dermabrasion and radiation.
- Trial name
- NCT00585338
- Testing
- Tandem 532/1064 nm Laser
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of California, Irvine
Port Wine Stains
Rapamycin Dose-Ranging Efficacy Study in Port Wine Stains
The goal of this clinical trial is to learn if the use of rapamycin cream can be used as a treatment together with pulsed dyed laser in treating port wine stain birthmarks.
- Trial name
- NCT07436611
- Testing
- Rapamycin cream, Pulsed dyed laser
- Where
- 2 sites in United States, Spain
- Volunteers
- 30 people
- Sponsor
- AFT Pharmaceuticals, Ltd.
Port Wine Stain
Dynamic Epidermal Cooling During Pulsed Dye Laser Treatment of Port Wine Stain Birthmark at High Fluences
The purpose of the study is to improve the efficacy of pulsed dye laser treatment of port wine stain birthmarks. Involvement in the protocol will involve formal documentation of the level of treatment pain, duration of…
- Trial name
- NCT00540371
- Testing
- Port wine stain Birthmark
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Hemangioma
Topical Timolol Gel for the Treatment of Infantile Hemangiomas
We plan to conduct a study, to see how safe and effective timolol maleate 0.5% gel-forming solution is for infantile hemangiomas (IH) and the response of hemangiomas to timolol maleate 0.5% .
- Trial name
- NCT02145884
- Testing
- timolol maleate 0.5% gel
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Rady Children's Hospital, San Diego
Infantile Hemangiomas
Ontogeny of Infantile Hemangiomas With Skin Imaging Modalities
A combined set of quantitative skin imaging methods will quantitatively describe the natural ontogeny and the response to standard treatments over time in patients with infantile hemangiomas.
- Trial name
- NCT02061735
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Melanoma
Treatment of Port Wine Stains in Children With Pulsed Dye Laser and Timolol Gel
Pulsed dye laser (PDL)is the gold standard treatment of port wine stains (PWS). However, many sessions are required and failure or relapses are not uncommon.
- Trial name
- NCT01272609
- Testing
- Timolol + LCP, LCP
- Where
- 10 sites in France
- Volunteers
- 25 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Infantile Hemangioma
Optical Tomographic Imaging of Infantile Hemangiomas
The investigators hypothesize that there are differences between infantile hemangiomas (IH) during the proliferating and involuting phases and in response to medical treatment that can be detected by optical tomography of these…
- Trial name
- NCT01673971
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Columbia University
Port-Wine Stain
Combined Pulsed Dye Laser and Topical Ranibizumab for Treatment of Port Wine Stain Birthmarks
The purpose of this study is to improve port wine stain therapeutic outcome in response to laser therapy. The researcher want to determine whether the combined use of pulsed dye laser therapy and topical ranibizumab will improve…
- Trial name
- NCT00667472
- Testing
- Ranibizumab, Pulsed Dye Laser
- Sponsor
- University of California, Irvine
Hippocampal Sclerosis, Dysembryoplastic Neuroepithelial Tumor
Exploration and Evaluation of Amygdalo-Hippocampectomy According to Prof. Coubes' Technique: An Anatomical, Clinical, and Educational Approach
The goal of this retrospective study is to evaluate the long-term clinical outcomes and complications associated with amygdalo-hippocampectomy using the surgical technique developed by Pr. Coubes (Montpellier, FRANCE).
- Conditions
- Hippocampal Sclerosis, Dysembryoplastic Neuroepithelial Tumor, Cortical Dysplasia, Ganglioglioma
- Trial name
- NCT06915649
- Testing
- Amygdalo-Hippocampectomy
- Where
- France
- Volunteers
- 3,504 people
- Sponsor
- University Hospital, Montpellier
Port-Wine Stain
Pilot Study to Evaluate the Effect of Multiple Passes on Port Wine Stain Treatments With the Cutera Excel V™ Laser.
Two limitations of single pulse, laser treatment of port-wine stains (PWS) are: (i) hemorrhage and purpura which may lead to post-treatment pigmentation and (ii) the necessity for repeated treatment sessions.
- Trial name
- NCT04103164
- Testing
- Cutera excel V™ Laser
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Hemangioma
A Clinical Trial of Pulsed-dye Laser Versus Timolol Topical Solution Versus Observation on the Growth of Hemangioma in Newborn
The purpose of this study is to find out if pulsed dye laser treatment or timolol maleate 0.5% gel can help infants who have a hemangioma.
- Trial name
- NCT01873131
- Testing
- topical timolol maleate, Pulsed dye laser
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital