Clinical trials: Port Wine Stains
Port-Wine Stain
Pathogenic Mechanisms of Port Wine Stain and Repository of Port Wine Stain Biopsy Samples
The purpose of this study is to investigate the pathogenic mechanisms of Port Wine Stain, collect biopsy samples and blood samples to characterize exosomes and metabolites from Port Wine Stain.
- Trial name
- NCT02051101
- Testing
- Biopsy sample from Port Wine Stain Birthmark
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Malignant Melanoma, Merkel Cell Carcinoma
Optical Biopsy of Human Skin in Conjunction With Laser Treatment
This study is to compare the ability of optical biopsy. Research can use light enters the skin, collected, analyzed by the computer, and a picture created for the pathologist to conventional histologic examination compare with…
- Conditions
- Malignant Melanoma, Merkel Cell Carcinoma, Basal Cell Carcinoma, Squamous Cell Carcinoma
- Trial name
- NCT00540566
- Testing
- Optical Biopsy imaging
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Telangiectases, Port Wine Stain
Evaluation and Optimization of the Technical and Clinical Performance of the Lumenis ONE Platform
The Intense Pulsed Light (IPL) technology, by selective phototermolysis, is used for eliminating, among other application, benign vascular lesions and unwanted leg veins. Light energy heats the deeper structures of the skin.
- Trial name
- NCT00247299
- Testing
- IPL Quantum Product manufactured by Luminis Ltd.
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Port-Wine Stain
Pilot Study to Evaluate the Effect of Multiple Passes on Port Wine Stain Treatments With the Cutera Excel V™ Laser.
Two limitations of single pulse, laser treatment of port-wine stains (PWS) are: (i) hemorrhage and purpura which may lead to post-treatment pigmentation and (ii) the necessity for repeated treatment sessions.
- Trial name
- NCT04103164
- Testing
- Cutera excel V™ Laser
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Port-wine Stain
Evaluate the Port-wine Stain Birthmark Treatment Before and After Pulsed Dye Laser Treatment
Port-wine stain is a congenital, progressive vascular malformation of human skin involving post-capillary venules that occurs in an estimated 0.3% of children and can alter personality development and psychological in children.
- Trial name
- NCT01774552
- Testing
- Photo Acoustic Microscopy and Optical Coherence tomography
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Port-Wine Stain
Treatment of Port Wine Stains Using Pulsed Dye Laser, Erbium Yag Laser and Topical Sirolimus
The purpose of this study is to improve the therapeutic outcome of laser therapy for port wine stains by using a combination treatment of the pulsed dye laser (PDL), erbium yag laser and topical sirolimus.
- Trial name
- NCT02214706
- Testing
- Sirolimus, Erbium yag laser, Pulsed Dye Laser
- Where
- Netherlands
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Port-Wine Stain
Measurement Skin Temperature During Pulsed Laser Exposure
Lasers are the treatment modality of choice for Port Wine Stain birthmarks.The epidermis is not totally spared due to partial absorption of energy therein by melanin that presents an optical barrier through which the light must…
- Trial name
- NCT00540917
- Testing
- cooling spray during laser treatment
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Port-Wine Stain, Rosacea
Skin Imaging to Inform Laser Treatments
The purpose of this study is to obtain information (such as lesion depth, depth of the most superficial part of the lesion, and the size and density of blood vessels) with the assistance of an imaging device, and use this…
- Conditions
- Port-Wine Stain, Rosacea, Telangiectasia, Angioma
- Trial name
- NCT04336163
- Testing
- Optical Coherence Tomography
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Port-Wine Stain
KTP Laser vs Pulsed Dye Laser for Port-Wine Stains
To compare the efficacy and safety of 532nm KTP laser and 585 nm pulsed dye laser for treating port-wine stains.
- Trial name
- NCT05771311
- Testing
- KTP, PDL
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Port Wine Stain
Dynamic Epidermal Cooling During Pulsed Dye Laser Treatment of Port Wine Stain Birthmark at High Fluences
The purpose of the study is to improve the efficacy of pulsed dye laser treatment of port wine stain birthmarks. Involvement in the protocol will involve formal documentation of the level of treatment pain, duration of…
- Trial name
- NCT00540371
- Testing
- Port wine stain Birthmark
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Rosacea, Vascular Diseases
Vbeam Pro Pulse Dye Laser for the Treatment of Vascular Conditions
This is a clinical study to evaluate the safety and performance of the Vbeam Pro Laser System for the treatment of vascular indications, including rosacea and port wine stain birthmarks.
- Conditions
- Rosacea, Vascular Diseases, Port-Wine Stain
- Trial name
- NCT07290426
- Testing
- Vbeam Pro Laser Treatment
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Candela Corporation