Clinical trials: Positron Emission Tomography
PET/CT
Evaluation of Attenuation Correction Accuracy in Positron Emission Tomography-Magnetic Resonance Imaging (PET-MRI)
The purpose of this research proposal is to establish a mechanism to develop tools that will allow the investigators to measure the impact of magnetic resonance (MR) acquisition correction sequences for attenuation correction on…
- Trial name
- NCT03423407
- Testing
- Positron Emission Tomography-Magnetic Resonance Imaging (PET-MRI)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Prostate Cancers
FACBC Positron Emission Tomography/Computed Tomography(PET/CT) Used in the Diagnosis of Primary Prostate Cancer
The purpose of this research project is to test if a compound (chemical substance) has a natural tendency to go to prostate cancer. This compound has a small amount of radioactivity attached to it and is called a radiotracer.
- Trial name
- NCT00917865
- Testing
- anti [18F]FACBC
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- David M. Schuster, MD
Prostate Cancer
Prostate Hypoxia FAZA
The purpose of this study is to look for low levels of oxygen (hypoxia) in prostate cancer using a special x-ray test called a positron emission tomography (PET)scan.
- Trial name
- NCT01567800
- Testing
- 18F-Fluoroazomycin Arabinoside (18F-FAZA)
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- University Health Network, Toronto
Atopic Dermatitis, Vascular Inflammation
Trial on Vascular Inflammation in Atopic Dermatitis
A total of 30 subjects with moderate to severe atopic dermatitis. Thirty subjects without AD matched for sex, age and coronary artery disease risk factor with the AD subjects will also be included.
- Conditions
- Atopic Dermatitis, Vascular Inflammation, Coronary Atherosclerosis
- Trial name
- NCT02926807
- Testing
- FDG-PET Scan, MDCT, biopsy and blood collection
- Where
- Canada
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Innovaderm Research Inc.
Cervical Cancer Squamous Cell
MRI FDG PET Imaging Cervix
The standard treatment for cervix cancer at Princess Margaret Hospital is external radiation with chemotherapy followed by internal radiation, called brachytherapy.
- Trial name
- NCT01899404
- Testing
- 18-FDG PET/CT, DWI, DCE-MRI
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- University Health Network, Toronto
Uterine Cancer
[18F]FES PET/.CT in Uterine Cancer
Women with known or suspected recurrent or metastatic uterine cancer may be eligible for this study. Patients may participate in this study if they are at least 18 years of age, most participants will be receiving care at the…
- Trial name
- NCT05916196
- Testing
- 18F-Fluoroestradiol
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Cushing Syndrome
Modified Desmopressin (mDesmo) Using Cold-Kit for PET/CT
The incidence of Cushing syndrome (CS) is 1.2-3.2 cases per million per year, of which adrenocorticotropic Hormone (ACTH)-dependent disease comprises approximately 70-80% of cases.
- Trial name
- Ga-68 mDesmo (NCT06962202)
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Amphetamine-Related Disorders, Amphetamine Abuse
Investigation of Serotonin Neurotransmission in MDMA Users Using Combinated Dexfenfluramine Challenge and PET Imaging
Illicit use of the psychostimulant "Ecstasy" (3,4-methylenedioxymethamphetamine, MDMA) is considered a major public health issue.
- Trial name
- DEXFEN_PET (NCT01296802)
- Testing
- dexfenfluramine
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Healthy Volunteers, Diabetes Mellitus, Type 1
Evaluation of 18 F-FP-DTBZ Pancreatic PET Scanning as a Tool to Measure Beta Cell Mass
Type 1 diabetes mellitus (T1DM) develops when there is impaired insulin production due to loss of insulin producing cells (beta cells).
- Trial name
- NCT02236754
- Testing
- 18 F-FP-DTBZ, PET Scanning
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Columbia University
Liver Fibrosis, Pulmonary Fibrosis
Imaging of Pathologic Fibrosis Using 68Ga-FAP-2286
This is a single arm prospective pilot trial that evaluates the ability of a novel imaging agent (68Ga-FAP-2286) to identify pathologic fibrosis in the setting of hepatic, cardiac and pulmonary fibrosis.
- Conditions
- Liver Fibrosis, Pulmonary Fibrosis, Myocardial Fibrosis
- Trial name
- NCT05180162
- Testing
- 68Ga-FAP-2286, Positron Emission Tomography (PET)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Thomas Hope
Prostate Cancer
Clinical Management Decisions for Recurrent Prostate Cancer Patients Based on [11C]Acetate PET Scan
When evaluating prostate cancer patients for recurrent disease, computed tomography (CT), and magnetic resonance imaging (MRI) are both highly sensitive methods for detecting lymph nodes, but are not specific as to whether the…
- Trial name
- NCT01777061
- Testing
- [11C]Acetate
- Where
- United States
- Sponsor
- Wendell Yap, MD
Cervical Dystonia, Dystonia
Cholinergic Receptor Imaging in Dystonia
Background: Dystonia is a movement disorder in which a person s muscles contract on their own. This causes different parts of the body to twist or turn. The cause of this movement is unknown.
- Conditions
- Cervical Dystonia, Dystonia, Movement Disorder, Focal Dystonia
- Trial name
- NCT02689466
- Testing
- [18F]FP-TZTP
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Melanoma (Skin)
Zr89 + PET Companion Trial
Study of Zirconium Zr 89 Crefmirlimab Berdoxa PET/CT as an imaging biomarker for assessing an early response to therapy in patients with advanced melanoma on immunotherapy and hydroxychloroquine.
- Trial name
- NCT05279027
- Testing
- Zirconium Zr 89 Crefmirlimab Berdoxa
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Indication for a PET CT Exam
Development of an Integrated Positron Emission Tomography/Magnetic Resonance (PET/MR) System, Accessories and Components
The PET/MR device components and accessories are under development in order to optimize, validate and improve the design including improving the quality of images.
- Trial name
- NCT01992354
- Testing
- PET MR Device
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- GE Healthcare
Cervical Cancer
Feasibility of Pet-scan at Day 1 of Brachytherapy for Patients With Cervical Cancer
Interventional, exploratory, prospective and monocentric study which aim to study the feasibility of brachytherapy using a PET-scan
- Trial name
- TEP-Curie (NCT03315351)
- Testing
- Brachytherapy, PET-scan
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Centre Oscar Lambret
Multiple Sclerosis
[18F]F-DED PET Imaging of Reactive Astrocytes in Multiple Sclerosis
Despite significant advancements in multiple sclerosis (MS) treatment over the past decade, a specific imaging biomarker for predicting disease progression remains lacking.
- Trial name
- F-DED PET MS (NCT07805473)
- Testing
- [18F]fluorodeprenyl-D2
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Parc de Salut Mar
Multiple Sclerosis
PET Study in Multiple Sclerosis
While both conventional and advanced MRI techniques offer important insights into MS pathophysiology, important aspects of this inflammatory disorder are undetectable with existing MRI technology.
- Trial name
- NCT03787446
- Where
- Canada
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Solid Tumours
An Open Label Study To Investigate the Pharmacokinetics and Pharmacodynamics of Repeat Escalating Doses of the Oral AKT Inhibitor GSK2141795 by 18F FDG PET Analysis in Subjects With Ovarian Cancer
The purpose of this study is to explore the potential dose response relationship between the pharmacokinetics of GSK2141795 and [18F] FDG PET pharmacodynamic markers of glucose metabolism in tumor tissue.
- Trial name
- NCT01266954
- Testing
- GSK2141795
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- GlaxoSmithKline
Takayasu Arteritis
Impact and Utility of PET Versus Clinical Score for the Assessment of Inflammatory Activity in Takayasu Arteritis
The purpose of this study is to demonstrate that [18F]FDG PET is a a better method than clinical and laboratory values for the identification and assessment of inflammatory activity in patients with Takayasu Arteritis (TA)…
- Trial name
- NCT01532167
- Where
- Mexico
- Volunteers
- 26 people
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
Cystic Fibrosis
Quantification of Pulmonary Neutrophil Activity in Cystic Fibrosis Using Radiolabeled Fluorodeoxyglucose and PET Imaging
It has been shown that neutrophils (a specific type of cell) are involved in inflammation in the lungs of CF patients. Neutrophil levels in CF patients have been measured by bronchoalveolar lavage (BAL), which samples cells in…
- Trial name
- NCT00023465
- Testing
- FDG-PET, spirometry, bronchoscopy with BAL
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- National Center for Research Resources (NCRR)
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