Clinical trials: Positron-Emission Tomography
Myocardial Infarction, No-Reflow Phenomenon
Ticagrelor and Clopidogrel on Reperfusion in Patients With AMI
The patients with acute myocardial infarction (AMI) present high mortality and morbidity rate,even treated with stenting in the blocked heart vessels. The appearance of no-reflow is common after re-opening of the blocked vessel.
- Trial name
- NCT02233790
- Testing
- Ticagrelor, Clopidogrel
- Where
- China
- Volunteers
- 600 people
- Sponsor
- First Hospital of China Medical University
Ovarian Cancer, Primary Peritoneal Cancer
Positron Emission Tomography/Computed Tomography (PET/CT) in Relapsed Ovarian Cancer (MK-0000-143)
This study will characterize FDG-PET (18F-Fluorodeoxyglucose-Positron Emission Tomography) as an early response marker in recurrent, platinum-sensitive ovarian cancer treated with platinum-based therapy.
- Conditions
- Ovarian Cancer, Primary Peritoneal Cancer, Fallopian Tube Cancer
- Trial name
- NCT00959582
- Testing
- Comparator: 18-F-FDG PET/CT and Volumetric CT
- Volunteers
- 42 people
- Sponsor
- Merck Sharp & Dohme LLC
Parkinson's Disease (PD), Parkinson's Disease
Open-label Study to Evaluate Brain α-Synuclein Deposition Using PET and [18F]MK-0947 in Parkinson's Disease
This clinical study is being conducted to learn more about a new imaging drug called [18F]MK-0947, which is designed to help doctors see changes in the brain related to Parkinson's disease (PD).
- Conditions
- Parkinson's Disease (PD), Parkinson's Disease, Parkinson's Disease (Disorder)
- Trial name
- NCT07348250
- Testing
- [18F]MK-0947
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Invicro
Cerebrovascular Accident, Perceptual Disorders
Effectiveness of Rehabilitation on the Recovery of Patients Post Right Stroke With Unilateral Spatial Neglect
Unilateral spatial neglect (USN) is believed to be a disorder of attention, characterized by impairment in the ability to perceive or respond to stimuli presented to the contralesional space, and which is not attributable to…
- Trial name
- NCT00305513
- Testing
- The phasic alerting treatment
- Where
- Israel
- Volunteers
- 6 people
- Sponsor
- Hadassah Medical Organization
Migraine
Positron Emission Tomography (PET) Study of Brain Calcitonin Gene-Related Peptide (CGRP) Receptor Occupancy After Telcagepant Administration (MK-0974-067)
The purpose of this study is to determine the receptor occupancy (RO) associated with telcagepant (MK-0974) administration based on displacement of [11C]MK-4232 from the CGRP receptors in the brain using PET.
- Trial name
- NCT01315847
- Testing
- telcagepant, [11C]MK-4232
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Huntington's Disease
Follow-up Measurement of Brain PDE10A Enzyme Levels in Huntington´s Disease Gene Expansion Carriers
The aim of this study is to measure longitudinally the availability of the PDE10A enzyme in HDGECs using the radioligand [18F]MNI-659.
- Trial name
- LONGPDE10 (NCT02956148)
- Testing
- Radioligand [18F]MNI-659
- Where
- 7 sites in Denmark, Netherlands and 2 more
- Volunteers
- 45 people
- Sponsor
- CHDI Foundation, Inc.
Abdominal Aortic Aneurysm
Endoprosthesis Treatment Effects on Human Abdominal Aorta Aneurysms (AAA) Metabolic Activity
The purpose of this study is to determine whether Positron Emission Tomography imaging can help to predict the evolutivity of AAA treated with endovascular prosthesis.
- Trial name
- AAAendo (NCT01253252)
- Testing
- [18F] Fluorodeoxyglucose PET Scan Imaging, CT scan, Blood sampling for biological investigations
- Where
- 7 sites in France
- Volunteers
- 45 people
- Sponsor
- Central Hospital, Nancy, France
Multiple Myeloma (MM)
A Clinical Trial Evaluating the Safety Tolerability, Radiation Absorption Dose, Distribution, PET Imaging and Histological Expression of 68Ga-NOTA-SCH001 in Patients With Multiple Myeloma
Multiple myeloma is the second most common hematologic malignancy in adults, and no curative treatment currently exists. With the development of monoclonal antibodies for tumor therapy, identifying tumor-specific biomarkers has…
- Trial name
- NCT06925958
- Testing
- Flow cytometry
- Volunteers
- 15 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Oncology, Prostate Cancer
A Study of [18]F-PSMA-1007 in Patients With Known or Suspected Metastatic Prostate Cancer
A [18]F-PSMA-1007 PET/CT or PET/MRI scan are nuclear medicine tests used to create pictures of the whole body that may show where cells that express Prostate-Specific Membrane Antigen (PSMA) are found.
- Trial name
- NCT05712174
- Testing
- [18]F-PSMA-1007
- Where
- Canada
- Volunteers
- 176 people
- Sponsor
- AHS Cancer Control Alberta
Lobular Metastatic Breast Cancer
89Zr-atezolizumab PET Scan and Lobular Breast Cancer
The exploratory single center feasibility ImaGelato study is conducted as an imaging side study to the Dutch GELATO trial (Assessing efficacy of carboplatin and atezolizumab in metastatic lobular breast cancer).
- Trial name
- ImaGelato (NCT04222426)
- Testing
- 89Zr-atezolizumab PET scans
- Where
- Netherlands
- Volunteers
- 1 people
- Sponsor
- University Medical Center Groningen
Colon Cancer
18F-FDG PET/CT and Molecular Tumor Characterisation for Staging and Follow-up of Colon Cancer
The investigators are investigating the usefulness of 18F-Fluordeoxyglucose Positron Emission Tomography/ Computed Tomography (18F-FDG PET/CT) for staging and follow-up of colon cancer.
- Trial name
- COLOPET1 (NCT01636674)
- Testing
- 18F-fluordeoxyglucose positron emission tomography/ computed tomography
- Volunteers
- 66 people
- Sponsor
- Naestved Hospital
Giant Cell Arteritis, Large Vessel Giant Cell Arteriitis
Longitudinal Imaging in Patients With Large Vessel Vasculitis to Predict Further Disease Course
Longitudinal imaging in patients with large vessel vasculitis to predict further disease course
- Trial name
- NCT04204876
- Testing
- Magnet Resonance Imaging (MRI), PET/CT analysis
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University Hospital, Basel, Switzerland
Prostate Cancer
ZD4054 With Positron Emission Tomography/Magnetic Resonance Imaging (PET/MRI) for Prostate Cancer
The purpose of this research study is to assess the effects of ZD4054 on prostate cancer that has spread to the bones by using new imaging techniques.
- Trial name
- NCT01119118
- Testing
- ZD4054
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Wisconsin, Madison
Carotid Artery Plaque
Carotid Plaque Assessment Using 18Fluorine (18F) -Sodium Fluoride Positron Emission Tomography (PET) /MR
Carotid plaque can lead to ischemic stroke. Treatment of asymptomatic carotid plaque, based on degree stenosis, is still controversial.
- Trial name
- CARTIS (NCT02726984)
- Testing
- 18F-sodium fluoride PET/MR
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Hospices Civils de Lyon
Cardiac Sarcoidosis
Feasibility and Accuracy of Hybrid Magnetic Resonance and Positron Emission Tomography With 18F-Fluorodeoxyglucose in Diagnosing Cardiac Sarcoidosis
The purpose and objectives of the study is to establish the feasibility of the simultaneous PET/MR in patients with cardiac sarcoidosis, determine relationships between various imaging biomarkers like extracellular volume (ECV)…
- Trial name
- NCT03923049
- Testing
- hybrid PET/MRI
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Alabama at Birmingham
Atherosclerosis
Effects on Atherosclerosis Regression of Ezetimibe or Ezetimibe Plus Simvastatin; Evaluated by Fluorodeoxyglucose Positron Emission Tomography (FDG-PET)
18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) is a promising tool for identifying and quantifying vascular inflammation within atherosclerotic plaques.
- Trial name
- NCT00926055
- Testing
- Ezetrol (Ezetimibe), Vytorin (Ezetimibe + Simvastatin)
- Where
- South Korea
- Volunteers
- healthy volunteers welcome
- Sponsor
- Korea University
Coronary Artery Disease
Rubidium-82 - An Alternative Radiopharmaceutical for Myocardial Imaging(Rb-ARMI)
Cardiovascular (CV) disease is the leading cause of death in Canada. Fifty percent of all Tc-99m used in nuclear medicine is for the diagnosis of coronary artery disease (CAD) with SPECT myocardial perfusion imaging (MPI).
- Trial name
- Rb-ARMI (NCT01128023)
- Testing
- Myocardial perfusion imaging using Rb-82 PET or Tc-99m or Tl SPECT
- Where
- Canada
- Volunteers
- 10,000 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Coronary Artery Disease
Magnetic Resonance Imaging (MRI) Viability: Comparison of Myocardial Viability by Positron Emission Tomography and MRI
The purpose of this study is to compare cardiac MRI with positron emission tomography (PET) with fluorodeoxyglucose (FDG) to determine if cardiac MRI images are as good as, or better, than PET with FDG.
- Trial name
- NCT00166179
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Emory University
Uterine Cancer
[18F]FES PET/.CT in Uterine Cancer
Women with known or suspected recurrent or metastatic uterine cancer may be eligible for this study. Patients may participate in this study if they are at least 18 years of age, most participants will be receiving care at the…
- Trial name
- NCT05916196
- Testing
- 18F-Fluoroestradiol
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Alzheimer Disease, Mild Cognitive Impairment
Brain Insulin Resistance in Mild Cognitive Impairment
Alzheimer´s disease (AD) is the most common cause of dementia. The most important risk factor for AD is old age; modifiable risk factors for AD include metabolic risk factors, i.e. diabetes, and obesity.
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Positron Emission Tomography
- Trial name
- COINS (NCT06116188)
- Testing
- FDG-PET study
- Where
- Finland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.