Clinical trials: Post COVID-19 Syndrome
Post-acute Corona Virus 19 (COVID-19) (Long COVID)
Phase 2 Study of RSLV-132 in Subjects With Long COVID
The purpose of this study is to assess the efficacy (decrease in profound fatigue), safety and pharmacokinetics of RSLV-132 in subjects with long Corona Virus (COVID) syndome
- Trial name
- NCT04944121
- Testing
- RSLV-132, Sodium Chloride 0.9%
- Where
- 5 sites in United States
- Volunteers
- 112 people
- Sponsor
- Resolve Therapeutics
COVID-19, Post Intensive Care Syndrome
Aerobic Exercise and Covid-19 Survivors With Post-Intensive Care Syndrome (Pics)
To investigate the effects of aerobic exercise program on physical activity, aerobic capacity, anxiety\& depression in Covid-19 survivors discharged from Intensive Care Unit.
- Trial name
- NCT05341648
- Testing
- Aerobic Exercise Training, Home Plan
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Post-Acute COVID-19 Syndrome, Lung Disease With Polymyositis
Efficacy and Safety of Longidaza® for the Treatment of Patients With Residual Changes in the Lungs After COVID-19
The goal of this clinical study is to evaluate the efficacy and safety of Longidaza®, lyophilisate for preparation of solution for injection, at a dose of 3000 IU compared to placebo in the treatment of adult patients with…
- Conditions
- Post-Acute COVID-19 Syndrome, Lung Disease With Polymyositis, Fibrosis, Lung Diseases, Interstitial
- Trial name
- NCT06383819
- Testing
- Longidaza®
- Where
- 30 sites in Russia
- Volunteers
- 392 people
- Sponsor
- NPO Petrovax
COVID-19, Long Haul
Covid-19 Long Haul Preventative and Health Promotion Care Clinical Trial Acceleration Program.
Investigators are conducting a study on alternative treatments for patients who have received an current or previous positive COVID-19 diagnosis with mild-serve symptoms or undiagnosable condition after testing positive for…
- Trial name
- NCT06441955
- Testing
- Ritonavir-Boosted Nirmatrelvir (Paxlovid), Physiological Evaluation, Moderna COVID-19 Vaccine
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Well- Konnect Healthcare Services and Research Firm
Post-COVID19 Condition
Plasma Exchange Therapy for Post- COVID-19 Condition: A Pilot, Randomized Double-Blind Study
PAX is a prospective, randomized (1:1), double-blind, placebo-controlled study, that have as a objective to evaluate the safety and tolerability of plasma exchange (PE) in patients with Post Acute Covid-19 Syndrome (PCC)…
- Trial name
- NCT05445674
- Testing
- Plasma Exchange Procedure
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia
COVID-19, Long COVID
Effectiveness of Transcranial Direct Current in Patients With Persistent COVID-19 With Headaches and Chronic Pain.
This study aims to verify the efficacy/effectiveness of treatment with transcranial direct current stimulation (TDCS) in patients with Long Covid who experience headaches, migraines, and chronic pain, such as arthralgia and…
- Conditions
- COVID-19, Long COVID, Long Covid19, SARS CoV 2 Infection
- Trial name
- NCT05780450
- Testing
- Transcranial Direct Current Therapy (tDCS)
- Where
- 2 sites in Spain
- Volunteers
- 87 people
- Sponsor
- Fundación Universidad Católica de Valencia San Vicente Mártir
Post-intensive Care Syndrome, COVID-19
Clinical and Functional Characteristics of Patients Admitted for Severe COVID-19 Pneumonia
This research protocol aims to evaluate the impact of severe COVID-19 pneumonia requiring invasive mechanical ventilation (IMV) on health-related quality of life (HRQoL), functional capacity, muscle strength, and nutritional…
- Trial name
- EQOL-COVID (NCT06727474)
- Testing
- Health-Related Quality of Life (HRQoL) with EQ-5D-3L
- Where
- Argentina
- Volunteers
- 51 people
- Sponsor
- Hospital Nacional Profesor Alejandro Posadas
Long COVID, Post COVID-19 Condition
Investigating the Effectiveness of Vimida
This randomized controlled trial (RCT) with 160 patients suffering from fatigue after COVID-19 infection aims to investigate the effectiveness of the unguided digital therapeutic vimida for reducing post-COVID-19 fatigue.
- Trial name
- InvidiCO (NCT06251518)
- Testing
- vimida
- Where
- Germany
- Volunteers
- 160 people
- Sponsor
- Gaia AG
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
The Effect of Acupuncture Therapy on Cognitive Function in Post-COVID-19 Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Background of study: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a common sequela after SARS-CoV-2 infection(COVID-19). Cognitive dysfunction is one of the most common debilitating symptoms in ME/CFS.
- Trial name
- NCT07357688
- Testing
- Acupuncture
- Where
- 2 sites in China
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Xi Wu
Long Covid
Validation of Biomarkers for Long COVID in the LIINC Viral Immunopathogenesis and Persistence Repeat Donor Cohort (VIPER)
The purpose of this study is to better understand the biological changes associated with Long COVID and to identify laboratory tests (biomarkers) that may help diagnose the condition and measure how it changes over time.
- Trial name
- VIPER (NCT07770022)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Post-COVID / Long-COVID, POST-Covid 19
Effects of Hydrotherapy During Post-COVID-19 Rehabilitation
This randomized controlled study evaluates the effects of cold water hydrotherapy as an adjunct to standard rehabilitation in patients with Post-COVID Syndrome.
- Conditions
- Post-COVID / Long-COVID, POST-Covid 19, Post COVID Syndrome, Post-COVID Condition
- Trial name
- HydroCoVital A (NCT07013903)
- Testing
- Standard rehabilitation plus cold water hydrotherapy, Standard rehabilitation only
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Schön Klinik Berchtesgadener Land
Covid19
Nebulized PL for Post-COVID-19 Syndrome
To evaluate and compare nebulized platelet lysate to placebo control of saline administered via handheld nebulizer 1x daily for eight weeks to determine effect on lung function in patients with post-COVID-19 ARDS syndrome.
- Trial name
- NCT04487691
- Testing
- Nebulized Platelet Lysate, Nebulized Sterile Saline
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Regenexx, LLC
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2), HIV
COVID-19 Recovery Study: Symptoms and Biomarkers of Long COVID-19 in People Living With and Without HIV
This observational study will prospectively characterize the long-term symptoms and side effects of COVID-19 in cohorts of people living with and without HIV.
- Trial name
- NCT04958889
- Testing
- No intervention
- Where
- United States
- Volunteers
- 392 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Covid19
Post Covid Syndrome: Clinical Pattern and Functional Assessment
Aim(s) of the Research : 1. Identify post covid symptoms 2. prevalance of post covid syndrome among survivours
- Trial name
- NCT04561141
- Volunteers
- 85 people
- Sponsor
- Assiut University
COVID-19
Mechanisms Underlying Long-term Fatigue and Exercise Intolerance Following COVID-19
The MEXICO study is an observational study that aims to identify underlying mechanisms contributing to exercise intolerance in the presence of persistent COVID-19 symptoms (Long COVID).
- Trial name
- MEXICO (NCT04914754)
- Where
- United Kingdom
- Volunteers
- 51 people
- Sponsor
- University College, London
Long Covid19, Neuropsychiatric Symptom
Acupuncture for Post COVID-19 Condition (Long COVID) Neuropsychiatric Symptoms
In this study, a 12-week pragmatic, randomized, double-blinded clinical trial will be conducted to evaluate the efficacy of acupuncture for the treatment of long Covid neuropsychiatric symptoms and provide reference for clinical…
- Conditions
- Long Covid19, Neuropsychiatric Symptom, Acupuncture
- Trial name
- NCT06633666
- Testing
- Acupuncture
- Where
- Hong Kong
- Volunteers
- 160 people
- Sponsor
- Hong Kong Baptist University
SARS-CoV-2 Acute Respiratory Disease, Myalgic Encephalomyelitis
Does a Technology Enabled Multi-disciplinary Team-based Care Model for the Management of Long COVID and Other Fatiguing Illnesses Improve Clinical Care of Patients and Represent a Sustainable Approach Within a Federally Qualified Health Center?
The primary objective of the present research is to determine the effectiveness of Family Health Center of San Diego's Long COVID and Fatiguing Illness Recovery Program (LC\&FIRP) on clinician- and patient-level outcomes.
- Conditions
- SARS-CoV-2 Acute Respiratory Disease, Myalgic Encephalomyelitis, Chronic Fatigue Syndrome, Post-acute Sequelae of SARS-COV-2 Infection
- Trial name
- LC&FIRP (NCT05167227)
- Testing
- Extension for Community Healthcare Outcomes
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Family Health Centers of San Diego
SARS-CoV Infection, COVID-19
Mitoquinone/Mitoquinol Mesylate as Oral and Safe Postexposure Prophylaxis for Covid-19
Adults who do not have major health, kidney, gastrointestinal disease will be randomized to receive oral mitoquinone/mitoquinol mesylate (Mito-MES) versus placebo to prevent the development and progression of COVID-19 after…
- Trial name
- NCT05886816
- Testing
- Mitoquinone/mitoquinol mesylate
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
COVID-19, Tuberculosis
Tuberculosis as a Risk Factor for a Worse Outcome Post-Sars-CoV-2 Infection
This study has two main objectives. First, the clinical characteristics and outcomes of hospitalized patients with symptomatic Covid-19 disease will be compared between persons with a history of past or current TB infection or…
- Conditions
- COVID-19, Tuberculosis, Post-acute COVID-19 Syndrome
- Trial name
- Co-TB (NCT05643781)
- Where
- South Africa
- Volunteers
- 157 people
- Sponsor
- The Aurum Institute NPC
COVID-19, Post COVID-19 Condition
Safety and Efficacy of Hyperbaric Oxygen Therapy for Long COVID Syndrome
Long COVID Syndrome (Long COVID), Post Acute COVID-19 Syndrome (PACS) or Post COVID-19 Syndrome (PCS) is defined as 'signs and symptoms that develop during or following an infection consistent with COVID-19, continue for more…
- Conditions
- COVID-19, Post COVID-19 Condition, Post COVID-19 Condition, Unspecified, Post COVID Condition
- Trial name
- HOT-LoCO (NCT04842448)
- Testing
- Hyperbaric oxygen
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Karolinska University Hospital