Clinical trials: Post Cataract Surgery
Cataract Surgery
Post-Market Study on the Safety and Effectiveness of the OpHLINE OVD in Cataract Surgery
This post-market clinical study was designed to assess the safety and effectiveness of the OpHLINE Ophthalmic Viscosurgical Device (OVD) as an adjunct in cataract surgery.
- Trial name
- NCT07343973
- Testing
- Cataract Surgery by Phacoemulsification with Posterior Chamber Intraocular Lens Implantation (OpHLINE 1.4%), Cataract Surgery by Phacoemulsification with Posterior Chamber Intraocular Lens Implantation (OpHLINE 2%), Cataract Surgery by Phacoemulsification with Posterior Chamber Intraocular Lens Implantation (OpHLINE 3%)
- Where
- 2 sites in Spain
- Volunteers
- 69 people
- Sponsor
- i+Med S.Coop.
Cataracts
Show Improved Vision With the HOYA AF-1 Aspheric Intraocular Lens After Cataract Surgery
The doctors participating in this study are looking to show improved vision with the HOYA AF-1 aspheric intraocular lens after cataract surgery.
- Trial name
- NCT01382641
- Testing
- Hoya AF-1 IOL, Revital vision
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Innovative Medical
Cataract
A Prospective Clinical Study Evaluating Dexycu vs Prednisolone Acetate 1%
This is a post-approval, open-label, randomized, self-controlled prospective clinical study to evaluate the safety and ocular efficacy of Dexycu in controlling postoperative ocular pain and inflammation associated with cataract…
- Trial name
- NCT04273282
- Testing
- Dexycu intracameral dexamethasone, Prednisolone Acetate
- Where
- 2 sites in United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Research Insight LLC
Cataract Extraction, Corneal Astigmatism
Assessment of Visual Performance in Patients With Low Levels of Astigmatism
To assess visual performance in patients with low levels (0.5-0.75 Diopters) of corneal astigmatism.
- Trial name
- NCT00842231
- Testing
- Visual performance measures
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Ocular Inflammation and Pain
Phase II Study Evaluating Safety/Efficacy of OTX-DP for Treatment of Ocular Inflammation and Pain After Cataract Surgery
To evaluate the safety and efficacy of OTX-DP as a sustained release drug (dexamethasone) depot when placed in the canaliculus of the eyelid for the treatment of ocular inflammation and pain in subjects who have undergone…
- Trial name
- NCT01666210
- Testing
- OTX-DP (Dexamethasone punctum plug)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Ocular Therapeutix, Inc.
Cataract
Nepafenac Opthalmic Suspension 0.1% Compared to Acular LS for Treatment of Inflammation After Cataract Surgery
The purpose of this study is to compare the effectiveness of Nepafenac Ophthalmic Suspension, 0.1% eye drops to Acular LS eye drops, used before and after cataract surgery, for treating inflammation in the eye.
- Trial name
- NCT00333255
- Testing
- Nepafenac Ophthalmic Suspension, 0.1%
- Where
- United States
- Volunteers
- 267 people
- Sponsor
- Alcon Research
Bilateral Cataract, Unilateral Cataract
Comparison of the Safety and Efficacy of Ophtesis Bio 3% With a Similar 3% Sodium Hyaluronate OVD
Prospective, randomized, subject/evaluator-masked post market clinical study at up to 2 sites at Gemini eye clinic in Czech Republic. Randomization will be done by the eye surgeon.
- Trial name
- NCT05832749
- Testing
- Ophtesis Bio 3% ophthalmic viscosurgical device, Healon Endocoat 3% ophthalmic viscosurgical device
- Where
- 3 sites in Czechia
- Volunteers
- 296 people
- Sponsor
- Gemini Eye Clinic
Cataract, Lens Opacities
Implantation of a Trifocal Hydrophobic IOL in Patients That Underwent Refractive Surgery
Controlled, open label, prospective Post Market Clinical Follow-Up, single-center clinical study to investigate visual performance after implantation of a trifocal IOL (PhysIOL Pod L GF) in patients that underwent refractive…
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- NCT04054427
- Testing
- IOL implantation experimental
- Volunteers
- healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Inflammation Corneal, Pain, Postoperative
OCS-01 in Treating Inflammation and Pain in Post-cataract Patients
The DX-216 trial is a randomized, double-masked, placebo (vehicle)-controlled study evaluating the efficacy and safety of two doses of OCS-01 compared to vehicle in the treatment of inflammation and pain following cataract…
- Trial name
- SKYGGN (NCT04130802)
- Testing
- OCS-01 - Dexamethasone Cyclodextrin Nanoparticle Ophthalmic Suspension 1.5% mg/mL
- Where
- 4 sites in United States
- Volunteers
- 153 people
- Sponsor
- Oculis
Cataracts, Inflammation
Difluprednate Pediatric Study for the Treatment of Inflammation Post-Cataract Surgery
The primary objective of this study was to compare the safety and efficacy of Durezol™ compared to Pred Forte™ for the treatment of inflammation following cataract surgery in a pediatric population 0 to 3 years of age.
- Trial name
- NCT01124045
- Testing
- Difluprednate ophthalmic emulsion, 0.05%, Prednisolone acetate ophthalmic suspension, 1.0%
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Alcon Research
Corneal Edema After Cataract Surgery
A Study to Investigate the Safety and Efficacy of Ripasudil (K-321) Eye Drops After Cataract Surgery
The purpose of this study is to assess the safety and efficacy of K-321 in subjects after cataract surgery
- Trial name
- NCT05528172
- Testing
- Ripasudil
- Where
- 45 sites in United States, Puerto Rico
- Volunteers
- 330 people
- Sponsor
- Kowa Research Institute, Inc.
Cataract
A Study to Evaluate the enVista® Aspire (EA) Intraocular Lens in Subjects Undergoing Cataract Extraction
A Study to Evaluate the enVista® Aspire (EA) intraocular lens in Subjects Undergoing Cataract Extraction
- Trial name
- NCT06333028
- Testing
- enVista Aspire EA IOLs
- Where
- 7 sites in United States
- Volunteers
- 82 people
- Sponsor
- Bausch & Lomb Incorporated
Cataract
Clinical Study to Evaluate the RxSight Light Adjustable Lens With the Light Delivery Device in Subjects With Preoperative Corneal Astigmatism
For patients undergoing cataract surgery, the purpose of this study is to evaluate a patient's far vision without glasses and quality of vision after implantation and UV treatment of the RxSight Light Adjustable Lens…
- Trial name
- NCT03771352
- Testing
- RxSight RxLAL
- Where
- 3 sites in Germany, United Kingdom
- Volunteers
- 55 people
- Sponsor
- RxSight, Inc.
Cataract Surgery
Assessment of a Hand-held Femtosecond Laser to Perform Anterior Capsulorhexis During Cataract Surgery (Post-market Study)
The goal of this observationnal study is to supplement the data collected in the pre-market study and confirm the rate of capsular ruptures due to Rx (reducing its related confidence interval).
- Trial name
- PMCF_SEQ_Rx (NCT07362043)
- Testing
- Cataract surgery with Rx, a handheld femtosecond laser for anterior capsulotomy (CE-marked device used as intended)
- Where
- France
- Volunteers
- 106 people
- Sponsor
- Helix Surgical
Cataract
Visual Outcomes After Bilateral Surgical Cataract Phacoemulsification: AcrySof Toric IOL Implantation Compared to Monofocal IOL Implantation
The objectives of this study are to assess and compare bilateral uncorrected distance visual acuity and distance spectacle independence post bilateral implantation of AcrySof Toric Intraocular Lenses (IOLs) and monofocal IOLs.
- Trial name
- NCT01192321
- Testing
- Toric T3 - T9, Monofocal
- Where
- France
- Volunteers
- 9 people
- Sponsor
- Alcon Research
Ocular Inflammation and Pain
Efficacy and Safety of APP13007 for Treatment of Inflammation and Pain After Cataract Surgery
This Phase 3 study will evaluate APP13007 in comparison to the matching vehicle placebo in a randomized, parallel-group, double-masked fashion.
- Trial name
- NCT04739709
- Testing
- APP13007, 0.05%
- Where
- 35 sites in United States, Puerto Rico
- Volunteers
- 378 people
- Sponsor
- Formosa Pharmaceuticals, Inc.
Cataract
Confirmatory Study Nepafenac 0.3%
The purpose of this study was to assess the safety and efficacy of an investigational eye drop intended for the prevention and treatment of inflammation (swelling and redness) and pain in the eye after cataract extraction.
- Trial name
- NCT01109173
- Testing
- Nepafenac Ophthalmic Suspension, 0.3%, Nepafenac Ophthalmic Suspension, 0.1%, Nepafenac Ophthalmic Suspension 0.3% Vehicle
- Where
- United States
- Volunteers
- 2,120 people
- Sponsor
- Alcon Research
Adverse Events
ReSure Sealant Post Approval Study
This is a prospective multicenter observational post-approval registry study that will collect post-approval data relative to the incidence of pre-specified Adverse Ocular Events for cataract surgery patients treated with the…
- Trial name
- Clinical PAS (NCT02310815)
- Testing
- ReSure Sealant
- Volunteers
- 626 people
- Sponsor
- Ocular Therapeutix, Inc.
Postoperative Ocular Inflammation, Postoperative Ocular Pain
A Phase 3 Study Evaluating the Safety and Efficacy of TRIESENCE® (Injectable Suspension) for the Treatment of Ocular Inflammation and Pain After Ophthalmic Surgery
This study is designed to evaluate the safety and efficacy of TRIESENCE® (triamcinolone acetonide injectable suspension) in patients undergoing ophthalmic procedures.
- Trial name
- NCT07832552
- Testing
- TRIESENCE (triamcinolone acetonide injectable suspension)
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Harrow Inc
Cataract, Surgery
Comparison of Visual Outcomes After Implantation of the Synthesis Plus and Synthesis Plus Toric
Prospective controlled monocentric study to determine the non-inferiority of the distance-corrected intermediate visual acuity at 66 cm of the SYNTHESIS PLUS TORIC with respect to the SYNTHESIS PLUS IOL.
- Conditions
- Cataract, Surgery, IOL
- Trial name
- DETPLUST (NCT05561478)
- Testing
- Implantation of Synthesis Plus IOL (control device), Implantation of Synthesis Plus Toric IOL (investigational device)
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Cutting Edge SAS