Clinical trials: Post Cataract Surgery
Corneal Endothelial Damage Following the Hard Nuclear Cataract Surgery
A Randomized Study of Gas Bubble Technique in Cataract Surgery
To investigate the efficiency and safety of using "Gas Bubble Technique" to reduce corneal endothelial damage in hard nucleus cataract patients.
- Trial name
- NCT06636279
- Testing
- Gas bubble technique
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Sichuan Provincial People's Hospital
Meibomian Gland Dysfunction
Evaluation of Dry Eye and Meibomian Gland Dysfunction After Cataract Surgery
Meibomian gland dysfunction (MGD) is a common and important disease has been investigated the pathophysiology, diagnosis, treatment modalities of MGD, however, the changes of MGD after the cataract surgery, the most popular…
- Trial name
- NCT01942642
- Volunteers
- 48 people
- Sponsor
- Yonsei University
Cataract
Evaluation of the Aspheric ReSTOR IOL After Routine Cataract Extraction
The purpose of this study is to evaluate the visual outcomes and patient satisfaction after bilateral implantation of the aspheric ReSTOR multifocal intraocular lens (IOL) and compare it to a historical control group of patients…
- Trial name
- NCT00720005
- Testing
- Aspheric Acrysof ReSTOR intraocular lens
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina
Cataract
Dropless vs. Standard Drops Contralateral Eye Study
To compare the use of an injectable compound containing an antibiotic and an anti-inflammatory at time of cataract surgery to standard of care that is the use 3 different topical medications to prevent inflammation and infection…
- Trial name
- NCT02515045
- Testing
- TriMoxiVanc, Moxifloxacin HCl 0.5%, Ilevro
- Where
- 4 sites in United States
- Volunteers
- 59 people
- Sponsor
- Carolina Eyecare Physicians, LLC
Cataract
Prediction of Pseudophakodonesis of Intraocular Lenses
Compare visual acuity of patients after cataract surgery with implantation of an IOL clinical outcome measure in eyes with and without pseudoexfoliation syndrome or history of ocular trauma.
- Trial name
- NCT03751462
- Testing
- Purkinjemeter
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Diabetic Macular Edema
The Effect of Intravitreal Ozurdex on DME After Cataract Surgery
The purpose of this study is to assess the efficacy and safety of OZURDEX (dexamethasone intravitreal implant) 0.7 mg administered immediately after phacoemulsification and intraocular lens implantation in type 1 or 2 diabetic…
- Trial name
- NCT01748487
- Testing
- dexamethasone intravitreal implant (OZURDEX)
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University Health Network, Toronto
Astigmatism
Rotational Stability After Nanoflex Collamer Toric Intraocular Lens Implantation in Astigmatic Patients
This study aims to assess the rotational stability of the new collameric Nanoflex toric intraocular lens (T-IOL) by STAAR inserted in astigmatic patients after cataract surgery.
- Trial name
- T-IOL (NCT02412215)
- Testing
- Phacoemulsification with toric Nanoflex IOL implantation, NanoFlex toric Intraocular Lens
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Turin, Italy
Cataract After, Astigmatism
Influence of Residual Astigmatism on Visual Acuity in Patients Undergoing Cataract Surgery With Trifocal Intraocular Lens Implantation
MAIN OBJECTIVE: To assess the influence of residual astigmatism on visual acuity in the different lens foci in patients operated on for cataracts with a trifocal intraocular lens implant.
- Conditions
- Cataract After, Astigmatism, IOL, Visual Acuity
- Trial name
- NCT04387721
- Testing
- Kind of trifocal IOL
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Enrique Ordiñaga-Monreal, OD, MSc
Endophthalmitis
OTX-14-002: Device Exposure Registry
The objective of the study is to collect post-approval data relative to the incidence of endophthalmitis for cataract surgery patients treated with the FDA-approved ReSure Sealant when used by a broad group of physicians under…
- Trial name
- NCT02309736
- Testing
- ReSure Sealant
- Sponsor
- Ocular Therapeutix, Inc.
Ocular Inflammation
Safety and Efficacy Study of rEV131 in the Treatment of Ocular Inflammation After Cataract Surgery
The purpose of this study is to evaluate the safety and effectiveness of three concentrations of rEV131, a new investigational anti-inflammatory agent, compared to placebo (an inactive substance) and an FDA approved…
- Trial name
- NCT00353964
- Testing
- rEV131, Prenisolone sodium phosphate 1.0%, rEV131 vehicle
- Where
- United States
- Sponsor
- Evolutec Group
Cataract
Meibomian Gland Dysfunction (MGD) and Tear Cytokines After Cataract Surgery According to Preoperative Meibomian Gland Status
To investigate the possible mechanisms by which cataract surgery aggravates meibomian gland dysfunction (MGD), the investigators evaluated the changes in tear cytokines and ocular surface parameters after cataract surgery…
- Trial name
- NCT02411487
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Yonsei University
Normal Cornea, Post Laser Refractive Surgery
Evaluation of RTVue in Corneal Measurement
The purpose of this study is to evaluate RTVue measurement of the cornea in various ocular conditions to include normal, pathology, post refractive surgery and cataract.
- Conditions
- Normal Cornea, Post Laser Refractive Surgery, Cornea Pathology, Cataract Surgery
- Trial name
- NCT01220193
- Where
- 2 sites in United States
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Optovue
Ocular Inflammation
Study to Compare Differing Dosing Regimens of ISV-303 (Bromfenac in DuraSite) to Xibrom and Vehicle in Post Cataract Surgery Volunteers
The purpose of this study is to evaluate the ocular safety, tolerability, and efficacy in topical administration of differing dosing regimens of ISV-303 compared to vehicle and Xibrom™ when dosed for 2 weeks in…
- Trial name
- NCT01190878
- Testing
- ISV-303, DuraSite Vehicle, Xibrom™
- Volunteers
- 169 people
- Sponsor
- Sun Pharmaceutical Industries Limited
Cataract, Presbyopia Correction
Evaluation Of Patient Satisfaction And Quality Of Vision After EDOF Or Trifocal IOL Implantation
Brief Summary of the Study The goal of this clinical study is to compare the quality of vision and patient satisfaction after cataract surgery using two different approaches to multifocal intraocular lenses (IOLs).
- Trial name
- TRIEDOF IOLS (NCT07295119)
- Testing
- Fusion EDOF IOL Implantation, Bilateral Trifocal IOL Implantation
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Cataract
Corneal Protect Used During Cataract Surgery
This randomized controlled subject- and examiner-masked study comprised patients scheduled for cataract surgery.The patients will be randomly assigned to receive either balanced salt solution（BSS）or hydroxypropyl…
- Trial name
- CPUDCS (NCT02363530)
- Testing
- Hydroxypropyl ethylcellulose (HPMC) 2% gel, BSS
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cataracts
Endothelial Cell Loss After Phacoemulsification Intra and Supracapsular
Cataract is the clouding of the lens of the eye, which initially prevents clear vision and eventually progresses to blindness if left untreated.
- Trial name
- PERCEPOLIS (NCT02535819)
- Testing
- Subluxation, Divide and Conquer
- Where
- France
- Volunteers
- 294 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Cataract
A Study to Evaluate Real World Outcomes of the enVista® Aspire (EA) and Aspire Toric (ETA) Intraocular Lens in Subjects Undergoing Cataract Extraction
A study to evaluate the real-world clinical performance of the enVista Aspire and Aspire Toric intraocular lens (IOL) models EA and ETA and to assess surgeon and subject satisfaction
- Trial name
- NCT06594185
- Testing
- enVista Aspire EA or Aspire Toric ETA IOLs
- Where
- 62 sites in United States
- Volunteers
- 335 people
- Sponsor
- Bausch & Lomb Incorporated
Cataract, Presbyopia
Comparative Analysis of the Visual Performance and Patient Satisfaction After Cataract Surgery With Implantation of a Medicontur Monofocal (877PAY) or a Medicontur Extended Depth of Focus (877PEY) IOL
The purpose of this multi-center, prospective, randomized, comparative clinical investigation was to evaluate and compare the visual performance at far, intermediate and near distances, the presence of photopic phenomena and…
- Conditions
- Cataract, Presbyopia, Ametropia
- Trial name
- NCT06642779
- Testing
- VFQ- 25 (Visual Function Questionnaire), Optical Biometry, Slit lamps / Fundoscopy / Biomicroscopy
- Where
- 3 sites in Hungary
- Volunteers
- 64 people
- Sponsor
- Medicontur Medical Engineering Ltd
Cataract, Refractive Errors
Comparison of Intraocular Lens Power Calculation Methods After Corneal Laser Refractive Surgery in Axial and Refractive Ammertropia
The study aims at determining the best biometry calculation formula to be used in IOL calculation of cataract patients how previously underwent laser refractive correction surgery
- Trial name
- NCT01979172
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- The National Eye Hospital, Cairo, Egypt
Age-Related Macular Degeneration
Size Progression of Macular Degeneration After Cataract Surgery
The purpose of this study was to find out if in patients with non-exudative age-related macular degeneration (AMD), randomly assigned to cataract surgery, any AMD size progression or progression to exudative AMD could be detected…
- Trial name
- NCT01165801
- Testing
- Cataract Surgery
- Where
- Austria
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery