Clinical trials: Post Cerebral Hemorrhage
Aneurismal Subarachnoid Hemorrhage, Hypopituitarism
Hypopituitarism After Aneurismal Subarachnoid Hemorrhage
Introduction: Almost 50% of patients die after aneurismal subarachnoid hemorrhage (aSAH). 30% of the survivors suffer from neurological handicap and need permanent care (Suarez et al.).
- Conditions
- Aneurismal Subarachnoid Hemorrhage, Hypopituitarism, Neuropsychological Deficits
- Trial name
- NCT00962559
- Where
- Germany
- Volunteers
- 26 people
- Sponsor
- Universitätsmedizin Mannheim
Intracerebral Hemorrhage, Subarachnoid Hemorrhage
Improving Outcomes for Patients With Life-Threatening Neurologic Illness
Background: While the intensive care of patients with life-threatening brain illnesses has advanced tremendously, a large number of therapies are still without proper scientific support.
- Conditions
- Intracerebral Hemorrhage, Subarachnoid Hemorrhage, Intraventricular Hemorrhage, Nontraumatic Haemorrhage
- Trial name
- REACH (NCT04189471)
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- University of Maryland, Baltimore
Aneurysmal Subarachnoid Hemorrhage
Effect of Antiplatelet Therapy on Cognition After Aneurysmal Subarachnoid Hemorrhage
Deficits in memory, executive function, and language are common cognitive sequelae of aneurysmal subarachnoid hemorrhage (aSAH).
- Trial name
- NCT04548401
- Testing
- Antiplatelet Drug
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Nanjing Medical University
Aneurysm, Ruptured, Hyperglycemia
Shunt-dependency After aSAH - Role of Early Hyperglycaemia in CSF and Blood
The goal of this study is to confirm the association of early increased glucose levels in cerebro-spinal fluid (CSF) and ventriculo-peritoneal-shunt (VPS)-dependency also evaluating the influence of blood glucose on VPS…
- Conditions
- Aneurysm, Ruptured, Hyperglycemia, Hydrocephalus
- Trial name
- HCP-Glc (NCT06486909)
- Testing
- Cerebrospinal Fluid (CSF) Sample, Blood Serum Sample
- Where
- 3 sites in Switzerland
- Volunteers
- 160 people
- Sponsor
- Isabel Hostettler
Subarachnoid Hemorrhage, Aneurysmal, Vasospasm, Cerebral
Early Warning of Delayed Cerebral Ischemia
The goal of this observational study is to learn about the possibility to predict clinical course of subarachnoid hemorrhage (SAH) patients by performing the retrospective analysis of clinical data available in early…
- Conditions
- Subarachnoid Hemorrhage, Aneurysmal, Vasospasm, Cerebral, Ischemia, Outcome, Fatal
- Trial name
- EWoDCI (NCT06006975)
- Testing
- Computed Tomography (CT) and Computed Tomography Angiography (CTA), Multimodal physiological monitoring
- Where
- Lithuania
- Volunteers
- 250 people
- Sponsor
- Vilnius University
Subarachnoid Hemorrhage, Aneurysmal, Cerebrovascular Disorders
Safety , Feasibility and Preliminary Efficacy of Remote Ischemic Conditioning in Patients With Aneurysmal Subarachnoid Hemorrhage After Aneurysm Clipping
This study was designed to evaluate the safety and efficacy of remote ischemic conditioning (RIC) in patients with aneurysmal subarachnoid hemorrhage (aSAH) following surgical clipping.
- Conditions
- Subarachnoid Hemorrhage, Aneurysmal, Cerebrovascular Disorders, Brain Diseases, Stroke
- Trial name
- NCT06819657
- Testing
- Remote Ischemic Conditioning Treatment Instrument, Guideline-based therapy
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Beijing Tiantan Hospital
Subarachnoid Hemorrhage, Cerebral Vasospasm
Use of Brain Oxygen Tension Level and Cleaved-tau Protein to Detect Vasospasm After SAH
The purpose of this study is to investigate if brain oxygen levels, levels of a specific protein in the cerebrospinal fluid and blood (Cleaved-tau protein), and brain blood flow can predict spasm of brain blood vessels after…
- Trial name
- NCT00582868
- Testing
- Licox Brain Oxygen Monitor, CSF, Whole blood
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Wisconsin, Madison
ICH - Intracerebral Hemorrhage
Effect of Cilostazol in Promoting Hematoma Clearance After Intracerebral Hemorrhage
Intracerebral hemorrhage (ICH) is a dangerous form of stroke with high mortality rate. Other than evacuating the hematoma with surgical procedures, there is no current effective internal medicine treatment.
- Trial name
- EPOCH (NCT06504576)
- Testing
- Pletaal 100mg/tab, Conventional internal medicine treatment
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Hemorrhage, Intracranial Hemorrhages
Restarting Anticoagulation After Traumatic Intracranial Hemorrhage
Primary Objective: To identify the optimal interval to restart oral anticoagulation after traumatic intracranial hemorrhage that will minimize thrombotic events and major bleeding by performing a response adaptive randomized…
- Conditions
- Hemorrhage, Intracranial Hemorrhages, Bleeding, Trauma
- Trial name
- Restart tICrH (NCT04229758)
- Testing
- Anticoagulants
- Where
- United States
- Volunteers
- 1,100 people
- Sponsor
- University of Texas at Austin
Inflammation, Coagulation and Hemorrhagic Disorders
Inflammation and Coagulation Factors for Predicting Cerebral Edema After SAH
Explore the role of Inflammation and coagulation factors in cerebrospinal fluid for predicting persistent cerebral edema after subarachnoid hemorrhage
- Conditions
- Inflammation, Coagulation and Hemorrhagic Disorders, Cerebral Edema
- Trial name
- NCT06009016
- Testing
- Inflammatory factors and coagulation factors level in cerebrospinal fluid after subarachnoid hemorrhage
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Liver Cirrhosis
Embolization of Large Spontaneous Portosystemic Shunts for the Prevention of Post-TIPS Hepatic Encephalopathy
The purpose of this study is to determine whether transjugular intrahepatic portosystemic shunt (TIPS) combined with large spontaneous portosystemic shunts embolization are effective in the prevention of hepatic encephalopathy…
- Trial name
- NCT02156232
- Testing
- TIPS, SPSS embolization
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Air Force Military Medical University, China
Stroke, Cerebro-vascular Accident
Studying Fatigue and Movement After Stroke
The goal of this observational study is to learn how neuromuscular fatigue develops after stroke and how changes in brain activity, muscle activity, and their interaction contribute to reduced motor performance in stroke…
- Conditions
- Stroke, Cerebro-vascular Accident, Ischemia Stroke, Hemorrhage Stroke
- Trial name
- NCT07594938
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Pulmonary Injury After Intracerebral Hemorrhage
Efficacy and Safety of Baricitinib in the Post-intracerebral Hemorrhage Pulmonary Injury
Some patients with intracerebral hemorrhage will develop severe lung injury such as respiratory distress syndrome. Baricitinib has been approved by the FDA for severe pneumonia caused by the coronavirus, and has been used in the…
- Trial name
- BRIGHT (NCT06548802)
- Testing
- Baricitinib
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Tianjin Medical University General Hospital
Subarachnoid Hemorrhage, Aneurysmal
Artificial Intelligence in Subarachnoid Hemorrhage
The overall aim of this study is to, with the help of computer/data scientist and machine learning processes, analyse collected heart rate variability data in order to evaluate whether specific patterns could be found in patients…
- Trial name
- AISAH (NCT04415736)
- Testing
- No intervention, observational study
- Where
- Sweden
- Volunteers
- 64 people
- Sponsor
- Göteborg University
Cerebral Hemorrhage
Prognostic Value of Plasma Thrombospondin-1 Levels After Acute Intracerebral Hemorrhage
The current study was designed to investigate the change of plasma thrombospondin-1 levels and assess the prognostic predictive effect of plasma thrombospondin-1 levels in the patients with acute intracerebral hemorrhage.
- Trial name
- NCT02465671
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Jinhua People's Hospital
Subarachnoid Hemorrhage, Aneurysmal, Cerebrocardiac Syndrome
Mechanisms of Brain-Heart Injury of Post-Intracranial Hemorrhage
Intracranial hemorrhage is a condition characterized by high mortality rates and suboptimal functional outcomes. It precipitates both direct brain injury and subsequent secondary injuries, including delayed cerebral ischemia…
- Conditions
- Subarachnoid Hemorrhage, Aneurysmal, Cerebrocardiac Syndrome, Mass Spectrometry, Heart Failure
- Trial name
- NCT06906432
- Testing
- Multi-disciplinary assessment
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Chronic Subdural Hematoma
High Concentration Oxygen Therapy for Pneumocephalus in Chronic Subdural Haematoma: A Prospective Observational Study
Normobaric oxygen therapy was shown to be effective in reducing post craniotomy pneumocephalus. Theoretical assessment of normobaric oxygen therapy in treating pneumocephalus has shown that a higher level of oxygen concentration…
- Trial name
- NCT05143216
- Testing
- Low concentration oxygen group: Room air (0-2Litre Oxygen via Nasal Canula), High concentration oxygen group: Room air (12-15Litre Oxygen via Non-rebreather Mask)
- Where
- Hong Kong
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Dr. David Yuen Chung CHAN
Intracerebral Hemorrhage, Acute Ischemic Stroke
Biologic Mechanisms of Early Exercise After Intracerebral Hemorrhage
This study aims to determine whether in-bed cycle ergometry, early in the hospital course after a brain hemorrhage could balance damaging and reparative inflammation in the brain.
- Trial name
- BEACH (NCT04027049)
- Testing
- Supine cycle ergometry of the lower extremities
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Johns Hopkins University
Atrial Fibrillation, Stroke
Rivaroxaban vs. Warfarin for Post Cardiac Surgery Atrial Fibrillation
This prospective, randomized, active-controlled, parallel arm study compares the safety and financial benefits of arterial thromboembolism prophylaxis with Warfarin vs.
- Conditions
- Atrial Fibrillation, Stroke, Bleeding
- Trial name
- NEW-AF (NCT03702582)
- Testing
- Rivaroxaban, Warfarin
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Intracerebral Hemorrhage
Amyloid Imaging and Cognitive Impairment After Intracerebral Hemorrhage
To evaluate Pet AV-45 Amyloid imaging in the etiological diagnosis of primary non traumatic intracerebral hemorrhage (Cerebral Amyloid Angiopathy and hypertension related hemorrhage).We hypothesize that patients with lobar…
- Trial name
- COGHIC-AV45 (NCT01619709)
- Testing
- Pet AV-45
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Toulouse