Clinical trials: Post Cerebral Hemorrhage
Acute Ischemic Stroke, Endovascular Thrombectomy
A Predictive Model and Scoring System for Severe Complications After Endovascular Thrombectomy
To establish a predictive model and scoring system for predicting severe complications after thrombectomy. This scoring system can be used to identify high-risk patients after endovascular thrombectomy, guide the early use of…
- Conditions
- Acute Ischemic Stroke, Endovascular Thrombectomy, Symptomatic Intracranial Hemorrhage, Malignant Cerebral Edema
- Trial name
- NCT06290076
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Xuanwu Hospital, Beijing
Aneurysmal Rupture
Characteristics of Signal Intensity Gradient in Subarachnoid Hemorrhage After Aneurysmal Rupture
10-20% of patients with subarachnoid hemorrhage die before they arrive at the hospital, and about 25% die within 24 hours. About 1% of patients are diagnosed with cerebral aneurysms in imaging tests for health checkups, and many…
- Trial name
- NCT05450939
- Testing
- Signal intensity gradient
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Chonbuk National University Hospital
Intracerebral Hemorrhage
Studying Anakinra to Reduce Secondary Brain Damage After Spontaneous Haemorrhagic Stroke
The goal of this clinical trial] is to determine if anakinra can ameliorate the formation of perihaematomal oedema in patients with spontaneous intracerebral haemorrhage (ICH).
- Trial name
- ACTION (NCT04834388)
- Testing
- Anakinra
- Where
- Netherlands
- Volunteers
- 75 people
- Sponsor
- Radboud University Medical Center
Subarachnoid Hemorrhage
Changes in Physical, Cognitive and Emotional Function 5 and 10 Years After Aneurysmal Subarachnoid Hemorrhage (aSAH)
The current study is a continuation of the study "Effect of early rehabilitation in patients with acute aSAH" which was approved by the Regional Committee for Medical Research Ethics, South-East Norway, archive number 2011/2189…
- Trial name
- NCT02795533
- Testing
- Clinical follow-up
- Where
- Norway
- Volunteers
- 112 people
- Sponsor
- Oslo University Hospital
Cerebral Ischemia
Safety and Effect of SANGUINATE™ Infusion in Patients at Risk of Delayed Cerebral Ischemia (DCI) Following Subarachnoid Hemorrhage (SAH)
Safety and effect of SANGUINATE on patients DCI following SAH.
- Trial name
- NCT02323685
- Testing
- SANGUINATE™
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Prolong Pharmaceuticals
Subarachnoid Hemorrhage, Vasospasm, Intracranial
The Factors Cause Vasospasm After Aneurysmal Subarachnoid Hemorrhage
Extensive research has shown that the big event that leads to the initiation of vasospasm is the release of oxyhemoglobin (blood breakdown product).Depletion of NO synthase (19,20,21) was also noted after SAH.CSF is produced from…
- Trial name
- NCT00745758
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Subarachnoid Hemorrhage
Deferoxamine to Prevent Delayed Cerebral Ischemia After Subarachnoid Hemorrhage
The investigators will test the central hypothesis that DFO treatment after SAH may improve cerebrovascular regulation, mitigate ischemic neural injury, and serve as an effective neuroprotectant against delayed ischemic injury…
- Trial name
- NCT02216513
- Testing
- desferrioxamine (DFO)
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Brigham and Women's Hospital
Stroke, Cerebrovascular Accident (CVA)
Investigating Central Contributions to Fatigue Using Non-invasive Brain Stimulation
The goal of this interventional study is to understand the contribution of the central components to the manifestation of neuromuscular fatigue in stroke survivors.
- Conditions
- Stroke, Cerebrovascular Accident (CVA), Ischemia Stroke, Hemorrhage Stroke
- Trial name
- NCT07613970
- Testing
- Transcranial alternating current stimulation (tACS)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Decompressive Craniectomy, Brain Injuries
Good Prognosis Factors After Decompressive Craniectomy : a Ten-year Retrospective Study
Decompressive craniectomy is a treatment of refractory intracranial hypertension after various etiologies : malignant ischemic stroke, traumatic brain injury, intraparenchymal hemorrhage, aneurysmal subarachnoid hemorrhage…
- Conditions
- Decompressive Craniectomy, Brain Injuries, Treatment Outcome
- Trial name
- NCT04682951
- Testing
- Decompressive Craniectomy
- Where
- France
- Volunteers
- 544 people
- Sponsor
- Central Hospital, Nancy, France
Subarachnoid Hemorrhage
Impact of Cardiac Complications on Outcomes of Patients After Subarachnoid Hemorrhage
Patients with subarachnoid haemorrhage frequently develop cardiac complications affecting their outcome
- Trial name
- NCT04177329
- Volunteers
- 50 people
- Sponsor
- Assiut University
Intracerebral Hemorrhage
Triple Antihypertensive Medication After Intracerebral Hemorrhage for Blood Pressure Control
Intracerebral hemorrhage (ICH) is the second most common form of stroke, with an incidence of around 3000 cases per year in Hong Kong.
- Trial name
- TRIACT (NCT07458880)
- Testing
- Exforge HCT® or Three Individual drug amlodipine + valsartan + hydrochlorothiazide
- Where
- 4 sites in Hong Kong
- Volunteers
- 140 people
- Sponsor
- The University of Hong Kong
Atrial Fibrillation, Stroke
Anticoagulation With Rivaroxaban in Cardioversion -The ARC Study
The purpose of this study is to determine that a new drug called "Rivaroxaban®" is effective in preventing patients from forming clots after their heart rhythm has been reset by the cardiologist with an electrical device.
- Conditions
- Atrial Fibrillation, Stroke, Thrombo-embolism, Bleeding
- Trial name
- ARC (NCT01747746)
- Testing
- Rivaroxaban, Warfarin and Enoxaparin
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Cook County Health
Cerebral Vasospasm After Subarachnoid Hemorrhage
Invasive Diagnostic and Therapeutic Management of Cerebral Vasospasm After Aneurysmatic Subarachnoid Hemorrhage
Cerebral vasospasm(CVS) after subarachnoid hemorrhage (SAH) results in a considerable amount of transient or even permanent neurological deficits and poor outcome of the patients.
- Trial name
- IMCVS (NCT01400360)
- Testing
- Combination of TBA and intraarterial application of vasodilators
- Where
- 5 sites in Germany
- Volunteers
- 92 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Intracerebral Hemorrhage, Motor Impairment
Fluoxetine for Motor Recovery After Acute Intracerebral Hemorrhage
This is a randomized, double-blind, placebo-controlled, multicenter clinical trial that will be carried out in Mexico. The purpose of this study is to test whether a 3-month treatment with fluoxetine enhances motor recovery in…
- Trial name
- FMRICH (NCT01737541)
- Testing
- Fluoxetine
- Where
- 4 sites in Mexico
- Volunteers
- 32 people
- Sponsor
- Universidad Autónoma de Aguascalientes
Post-Traumatic Subarachnoid Hemorrhage
Superior Cervical Sympathetic Block Versus Stellate Ganglion Block in Post-traumatic Subarachnoid Hemorrhage
Posttraumatic Subarachnoid hemorrhage (SAH) is a life-threatening neurological problem with a high mortality rate. Delayed cerebral ischemia (DCI) is the second-leading cause of death and disability in patients suffering from…
- Trial name
- NCT06134583
- Testing
- Superior cervical sympathetic block group, Stellate ganglion block group
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Neonatal Seizure, Hypoxic-Ischemic Encephalopathy
Neonatal Seizure Registry, GEnetics of Post-Neonatal Epilepsy
The NSR-GENE study is a longitudinal cohort study of approximately 300 parent-child trios from the Neonatal Seizure Registry and participating site outpatient clinics that aims to evaluate whether and how genes alter the risk of…
- Conditions
- Neonatal Seizure, Hypoxic-Ischemic Encephalopathy, Stroke, Intracranial Hemorrhage
- Trial name
- NSR-GENE (NCT05361070)
- Where
- 8 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of California, San Francisco
Atrial Fibrillation, Bleeding
HEAL-LAA Clinical Trial
The primary objective of this study is to collect real-world data on WATCHMAN FLX™ Pro Left Atrial Appendage Closure (LAAC) Device in patients with non-valvular atrial fibrillation.
- Conditions
- Atrial Fibrillation, Bleeding, Stroke
- Trial name
- HEAL-LAA (NCT05809596)
- Testing
- WATCHMAN FLX Pro LAAC Device
- Where
- 45 sites in United States
- Volunteers
- 949 people
- Sponsor
- Boston Scientific Corporation
Subarachnoid Hemorrhage
Short Duration Levetiracetam to Extended Course for Seizure Prophylaxis After aSAH
Our primary objective is to compare two treatment options for prevention of seizures following a subarachnoid hemorrhage and determine if a short-course regimen of levetiracetam is as efficacious in the prevention of in-hospital…
- Trial name
- DOPAST (NCT01137110)
- Testing
- Brief LEV, Extended LEV
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Washington University School of Medicine
Subarachnoid Hemorrhage
Ultra-early Tranexamic Acid After Subarachnoid Hemorrhage.
This is a multicenter, prospective, randomized, open-label trial with blinded endpoint (PROBE) assessment. Adult patients with the diagnosis of non-traumatic SAH, as proven by computed tomography (CT) within 24 hours after the…
- Trial name
- ULTRA (NCT02684812)
- Testing
- Tranexamic Acid
- Where
- Netherlands
- Volunteers
- 955 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Ischemic Stroke
Reperfusion Injury After Endovascular Stroke Treatment
Endovascular stroke treatment with mechanical thrombectomy (MT) has become the standard therapy for intracranial large vessel occlusion (LVO).
- Trial name
- DYNASTROKE (NCT05273216)
- Testing
- Transcranial Duplex Sonography, Brain MRI, Blood biomarkers
- Where
- 3 sites in Austria
- Volunteers
- 600 people
- Sponsor
- Medical University of Graz