Clinical trials: Post Coronary Bypass Surgery Patients
Frailty, Coronary Artery Disease
Funcional Recovery After Minithoracotomy or Sternotomy for CABG in Frail Patients
Frailty is a major predictor of adverse outcomes following coronary artery bypass grafting (CABG), being associated with increased postoperative complications, prolonged hospitalization, delayed functional recovery, and reduced…
- Conditions
- Frailty, Coronary Artery Disease, Coronary Artery Bypass Graft (CABG)
- Trial name
- MINIFRAGILE (NCT07742475)
- Testing
- Minimally Invasive Coronary Artery Bypass Grafting (MICS-CABG), Conventional Coronary Artery Bypass Grafting (Median Sternotomy)
- Volunteers
- 194 people
- Sponsor
- University of Sao Paulo General Hospital
Coronary Artery Bypass
Oropharyngeal Humidification After Extubation on Thirst
In patients who have undergone endotracheal intubation following cardiac surgery, symptoms such as thirst, dysphagia (difficulty swallowing), restlessness, nausea, and vomiting are frequently observed, and these conditions…
- Trial name
- NCT07397221
- Testing
- Oropharyngeal Humidification with Water Spray
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Muş Alparslan University
Coronary Artery Disease (CAD), Coronary Artery Bypass Graft Surgery (CABG)
Examining the Effects of Video-Assisted Discharge Education After Coronary Artery Bypass Graft Surgery on Patient Satisfaction and Anxiety
This study was conducted to examine the effects of standard and individualized video-assisted discharge education on patient satisfaction and anxiety levels following Coronary Artery Bypass Graft (CABG) surgery.
- Conditions
- Coronary Artery Disease (CAD), Coronary Artery Bypass Graft Surgery (CABG), Postoperative Discharge Education
- Trial name
- NCT07528859
- Testing
- video discharge education, individual video discharge training, discharge education
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass
A Comparison Between 5% Albumin and 6% Hydroxyethyl Starch 130/0.4 in Priming Solution for Cardiopulmonary Bypass and Post-bypass Maintenance Fluid in High-risk Patients
It is advantageous to use 5% human albumin (HA) in patients undergoing cardiopulmonary bypass (CPB), because preexposure of the synthetic surfaces of the CPB circuit to albumin decreases coagulopathy, platelet aggregation, immune…
- Trial name
- NCT01644084
- Testing
- Hydroxyethyl starch 130/0.4
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Yonsei University
Focus of Study, Coagulation Status of Cardiac Surgery Patient
Thromboelastography-derived Functional Fibrinogen Levels
This study hopes to determine if thromboelastography-derived functional fibrinogen (TEG-FF or FLEV) levels obtained during the rewarming phase of cardiopulmonary bypass can provide information on coagulation status sooner…
- Conditions
- Focus of Study, Coagulation Status of Cardiac Surgery Patient, Reducing Excess Blood Transfusion
- Trial name
- TEG-FF (NCT01992757)
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Pennsylvania
Kidney Failure, Chronic, Coronary Artery Disease
Prophylactic Effect of Nifedipine on Further Decline in Renal Function in Patients Undergoing Open-Heart Surgery
To compare renal function (51Cr-EDTA clearance) 48 hours post open-heart surgery (coronary bypass or valve surgery) in patients with impaired renal function after randomization to either nifedipine infusion at start of surgery…
- Trial name
- NCT00244530
- Testing
- Nifedipine
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- University of Oslo School of Pharmacy
Multivessel Coronary Artery Disease
Cost-effectiveness of PCI With Taxus vs CABG - 5 Years FUP
The objective of the present study is to analyze the cost-effectiveness of percutaneous coronary intervention (PCI) using TAXUS stents compared to the costs of coronary artery bypass surgery (CABG) in patients with multivessel…
- Trial name
- NCT01199419
- Testing
- comparison of PCI vs. CABG in multivessel disease
- Where
- Austria
- Volunteers
- 207 people
- Sponsor
- Medical University of Vienna
Cardiac Surgery
Catecholamine-O-Methyl-Transferase(COMT)-Polymorphism in Cardiac Surgery
Although clinical risk factors for postoperative development of vasodilatory shock and acute renal failure have been identified; there is a considerable proportion of patients undergoing cardiac surgery where this syndrome cannot…
- Trial name
- NCT00334009
- Where
- Australia
- Volunteers
- 250 people
- Sponsor
- Austin Health
Intracranial Embolism and Thrombosis, Postoperative Complications
TCD Detection of Gas and Solid Micro-Emboli in Patients Undergoing Coronary Artery Bypass Grafting (CABG): The Influence of Proximal Anastomosis Technique
The purpose of this study is to test the hypothesis that using three different techniques to anastomose coronary grafts to the aorta: partial occlusion, single cross clamp, or using the Heartstring anastomotic device, will change…
- Trial name
- NCT00294814
- Testing
- Proximal anastomosis using Heartstring anastomotic device
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Rambam Health Care Campus
Chronic Coronary Syndrome, Atrial Fibrillation
SGLT2 Inhibitor TrEatment iN Patients Awaiting cOronary arTery bYpass Surgery to Reduce Post-opErative AF
The goal of this randomized, double-blinded, controlled clinical trial is to investigate if treatment with an sodium-glucose cotransporter-2 inhibitor (SGLT2) during the unique time window before coronary artery bypass surgery…
- Trial name
- STENOTYPE (NCT05852704)
- Testing
- Dapagliflozin 10mg Tab
- Where
- 8 sites in Czechia, Denmark and 1 more
- Volunteers
- 800 people
- Sponsor
- Region Örebro County
Post-operative Atrial Fibrillation, CABG
Empagliflozin to Prevent Post-Operative Atrial Fibrillation
This is an interventional, double-blind, placebo controlled, multicenter, randomized clinical trial with allocation sequence concealment and blinded endpoint adjudication.
- Trial name
- EMPOAF (NCT06124937)
- Testing
- Empagliflozin 10 MG
- Where
- 2 sites in Iran
- Volunteers
- 492 people
- Sponsor
- Rajaie Cardiovascular Medical and Research Center
Coronary Arterial Disease (CAD), Coronary Artery Bypass Graft (CABG)
Comparison of Oxygen Reserve Index and Spirometry in Predicting Respiratory Complications After Coronary Artery Bypass Surgery
Coronary artery disease (CAD) is one of the most common cardiac conditions, primarily caused by atherosclerosis. Studies have shown that environmental factors such as lifestyle, diet, genetics, and air pollution contribute to the…
- Conditions
- Coronary Arterial Disease (CAD), Coronary Artery Bypass Graft (CABG), Postoperative Pulmonary Complication
- Trial name
- NCT07063277
- Testing
- Preoperative Evaluation with ORI and Spirometry
- Where
- Turkey (Türkiye)
- Volunteers
- 142 people
- Sponsor
- Ankara Bilkent Sehir Hastanesi
Acute Kidney Injury
Study to Prevent Acute Kidney Injury After Cardiac Surgery Involving Cardiopulmonary Bypass
The objective of the study is to assess the safety and efficacy of ANG-3777 in preventing AKI compared to placebo when administered to patients at risk for developing acute kidney injury (AKI) following cardiac surgical…
- Trial name
- NCT02771509
- Testing
- ANG-3777
- Where
- 40 sites in United States, Brazil and 2 more
- Volunteers
- 275 people
- Sponsor
- Angion Biomedica Corp
Coronary Artery Disease
Dynamic Arterial Elastance for Prediction of Vasopressor Requirement After Anesthesia Induction in Elective On-Pump CABG
This study aims to determine whether dynamic arterial elastance (EaDyn), measured after anesthesia induction, can predict the need for vasopressor treatment in patients undergoing elective on-pump coronary artery bypass graft…
- Trial name
- NCT07871201
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Elzem SEN
Coronary Artery Disease, Anemia
Clinical and Chemical Outcomes Following Cardiac Surgery: The Post-Operative Effects of MUF
It is hypothesized that on-line modified ultrafiltration (MUFF) post-cardiopulmonary bypass will result in improved patient outcomes over the 12-hour post-operative period as compared to control and off-line MUFF.
- Trial name
- MUF (NCT01864395)
- Testing
- Centrifugation Method, Online MUF, Offline MUF
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- University of Saskatchewan
Telehealth, Coronary Artery Bypass Surgery
The Effectiveness of a Telehealth Program on Cardiac Symptom Distress, Self-care and Quality of Life of Patients With Coronary Artery Disease After Coronary Artery Bypass Surgery: A Randomized Study
The goal of this randomized trial is to compare the outcomes of a telehealth program with conventional discharge care for patients aged 18 years and older with coronary artery disease following coronary artery bypass surgery.
- Trial name
- NCT06648291
- Testing
- QOCA EKG Device, Usual Care
- Where
- Taiwan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Acute Respiratory Distress Syndrome
Extravascular Lung Water and Pulmonary Vascular Permeability After Minimally Invasive Cardiac Surgery
The use of cardiopulmonary bypass (CPB) combined with one lung ventilation (OLV) allows to perform minimally invasive cardiac surgery (MICS) through small incisions.
- Trial name
- NCT02155387
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital Freiburg
Post-discharge Outcomes
Retrospective Observational Study of Patients Who Have Undergone Coronary Artery Bypass Graft (CABG) and/or Cardiac Valve Surgery
This study is a retrospective chart abstraction for subjects who were enrolled in REN-004. As a retrospective study, all data will be abstracted from the medical records.
- Trial name
- NCT07009340
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Renibus Therapeutics, Inc.
Hemostatic Disorders
Blood Products Transfusion in Cardiac Surgery After the Implementation of a Coagulation Monitoring System at Patient Bedside: Thromboelastometry Versus Standard Transfusion Protocol
Main objective: Determine whether by introducing thromboelastograph, the investigators reduced the number of packed red cells received by each patient (median) compared to the usual protocol, in which the indication for…
- Trial name
- ROTEM-2010 (NCT01919840)
- Testing
- Group ROTEM, Group C
- Volunteers
- 49 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Peak Expiratory Flow Rate, Coronary Artery Bypass Graft Surgery
Additional Effects of Flutter With Conventional Chest Physiotherapy on Peak Expiratory Flow Rate and Chest Expansion in Post CABG Patients With COPD
Flutter therapy is an oscillating positive expiratory pressure (OPEP) technique that combines positive expiratory pressure with airway oscillations to facilitate mobilization and clearance of respiratory secretions.
- Conditions
- Peak Expiratory Flow Rate, Coronary Artery Bypass Graft Surgery, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT07875049
- Testing
- Conventional Chest Physiotherapy, Flutter device with conventional chest physiotherapy
- Where
- Pakistan
- Volunteers
- 84 people
- Sponsor
- Foundation University Islamabad