Clinical trials: Post Discharge
Opiate Dependence
Outcomes of Opioid Addicted Prisoners With Extended-Release Injectable Naltrexone
This study is a collaboration between the University of Pennsylvania, the Philadelphia Prison System, and the North East Treatment Center (NETSteps).
- Trial name
- OAPXRNTX (NCT02617628)
- Testing
- extended release naltrexone
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Laceration of Skin, Anxiety
IN Midazolam vs IN Dexmedetomidine vs IN Ketamine During Minimal Procedures in Pediatric ED
Pain in young children has been universally under-recognized due to their inability to describe or localize pain. Improvements in pharmacological interventions are necessary to optimize patient and family experience and allow for…
- Conditions
- Laceration of Skin, Anxiety, Discharge Time
- Trial name
- NCT05934669
- Testing
- Intranasal Midazolam, Intranasal Dexmedetomidine, Intranasal Ketamine
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Post Mastectomy Lymphedema
Effect of Resisted Deep Breathing and Myofascial Release in Postmastectomy
This study aims to determine the combined effect of resisted deep breathing and Myofascial release on pain, respiratory efficiency, chest mobility and lymph edema in Postmastectomy.
- Trial name
- NCT07576270
- Testing
- Resisted Deep Breathing, Myofascial release
- Where
- Pakistan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Anxiety, Post Procedural Discharge
Effect of the Pecha-Kucha Method on the Discharge Readiness and Anxiety Levels
H1a: Between the women receiving discharge training with the PechaKucha method by using smartphones and the women taking the routine discharge training in the early postpartum period, there is a statistically significant…
- Conditions
- Anxiety, Post Procedural Discharge, PechaKucha Method
- Trial name
- NCT04696991
- Testing
- The postpartum discharge education with PechaKucha Method.
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Aysegul Durmaz
Healthy
Pharmacokinetics of Extended-Release Test- and Reference Formulations of AZD0837
The aims of this study are to evaluate the pharmacokinetics, safety and tolerability of the oral doses of the extended-release test- and reference formulations of AZD0837 in healthy volunteers both in fasting and fed conditions.
- Trial name
- NCT00878618
- Testing
- AZD0837
- Where
- Sweden
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Subarachnoid Hemorrhage, Lymphatic System Disorder
Radiological Changes of Glymphatic-meningeal Lymphatic Drainage System After Subarachnoid Hemorrhage
Subarachnoid hemorrhage (SAH) is a common and extremely critical disease in neurosurgery. The mortality rate within 30 days of the onset of SAH is as high as 50%, and about 15% of SAH patients die without reaching the hospital.
- Conditions
- Subarachnoid Hemorrhage, Lymphatic System Disorder, Meningeal Lymphatic Vessels
- Trial name
- NCT06444438
- Testing
- subarachnoid hemorrhage
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Hip Osteoarthritis, Bleeding
Closed Suction Drainage After Revision Hip Arthroplasty
Prospective, randomized trial. 40 patients who underwent revision hip arthroplasty, divided in to two groups with or without drainage. All patients was assessed with ultrasonography on 3rd day after surgery.
- Trial name
- NCT04486040
- Testing
- Drainage, No-drainage
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Prof A Gruca Teaching Hospital
Premature Baby 26 to 32 Weeks, Premature Babies
Effects of a Treatment Program Based on the Bobath Concept After Hospital Discharge in Children Born Very Preterm
INTRODUCTION: This project is presented as a continuation of the one approved in 2019 (Code: UALBIO2019/013). Early Intervention is defined as all interventions, including prevention, carried out with children aged 0-6 years…
- Conditions
- Premature Baby 26 to 32 Weeks, Premature Babies, Neurodevelopment Treatment, Neurodevelopment
- Trial name
- NCT07254780
- Testing
- Bobath, Early Intervention, Ordinary care
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad de Almeria
Premature - Weight 1000g-2499g or Gestation of 28-37weeks, Premature Birth
Evaluation of the Health Effects of the Air Purifier in Preterm Infants After Discharge
Participant's baby was born prematurely and had underdeveloped lungs at birth. Most premature infants require mechanical ventilation after birth, which increases the risk of lung injury and may lead to varying degrees of…
- Trial name
- NCT07236996
- Testing
- air purifier
- Where
- Taiwan
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Healthy
Study to Evaluate Pharmacokinetics of Dipyridamole in Three New Formulations of Asasantin ER in Healthy Female and Male Subjects
The objective of this study was to compare the pharmacokinetics of dipyridamole in three different Asasantin ER batches (test) containing different amounts of retarding lacquers to the existing commercial product at steady state…
- Trial name
- NCT02273544
- Testing
- Asasantin ER (new formulation - low), Asasantin ER (new formulation - medium), Asasantin ER (new formulation - high)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Pain
Assessment of the Pharmacokinetics of a Sustained Release Formulation of a Tramadol/Acetaminophen Combination
1. Objective: To evaluate the pharmacokinetic profiles of an SR 75 mg tramadol/650 mg acetaminophen formulation compared with an immediate release (IR) 37.5 mg tramadol/325 mg acetaminophen formulation after a single dose and at…
- Trial name
- NCT01880125
- Testing
- Tramadol HCI/Acetaminophen
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Yungjin Pharm. Co., Ltd.
Drainage, Laparoscopic Cholecystectomy
The Efficacy and Safety of Using Prophylactic Abdominal Drainage After Cholecystectomy
Investigators want to assess the safety and efficacy of using abdominal drainage with not using any drainage, by estimating different outcomes after laparoscopic cholecystectomy for different reasons.
- Conditions
- Drainage, Laparoscopic Cholecystectomy, Acute Cholecystitis
- Trial name
- NCT05267860
- Testing
- Prophylactic Drain
- Where
- Syria
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- University of Aleppo
Peritonsillar Abscess
Assessing the Necessity of Prescribing Antibiotics (Clavulin or Clindamycin Versus Placebo) Post-peritonsillar Abscess Drainage
This study aims to look at the necessity for prescribing antibiotics post-drainage of peritonsillar abscesses (PTA). This will be a single-blinded randomized-control trial with two arms - patients receiving placebo versus those…
- Trial name
- PTA (NCT01715610)
- Testing
- Clavulin, Clindamycin
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Melatonin
Effects of Melatonin and Massage After Third Molar Surgery
Lymphatic drainage massage is an important practice, especially for reducing edema. It is a very gentle, monotonous, slow, rhythmic massage applied to the skin surface.
- Trial name
- NCT06812026
- Testing
- no melatonin and massage, receive melatonin, receiving lymphatic drainage
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Insomnia
Residual Effects of Zolpidem Tartrate Extended Release and Eszopiclone Vs Placebo
Investigation of Psychomotor and Cognitive Residual Effects of Single Oral Doses of Zolpidem Tartrate Extended Release 12.5 mg and Eszopiclone 3 mg Compared to Placebo in Healthy Young Volunteers, Using Flurazepam 30 mg as an…
- Trial name
- NCT00283790
- Testing
- zolpidem tartrate
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Sanofi
Pharmacokinetics
A Single Dose, Cross-over Bioequivence Study Comparing Galantamine IR (Immediate Release) Table and Galantmine OS (Oral Solution) in Healthy Volunteers
The purpose of this open-label, single dose, two-treatment, two-period, cross-over study is to evaluate the pharmacokinetic profile and tolerability of galantamine oral solution and galantamine tablet.
- Trial name
- NCT00645554
- Testing
- Galantamine oral solution
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Xian-Janssen Pharmaceutical Ltd.
Attention Deficit Hyperactivity Disorder (ADHD)
A Long Term Post-Marketing Study on the EffIcacy and Safety of Osmotic Release Oral System (OROS) Methylphenidate on the Cognitive Functions of Attention Deficit Hyperactivity Disorder (ADHD) Participants
The purpose of this long term post-marketing study is to evaluate the effectiveness and safety of osmotic release oral system methylphenidate hydrochloride (OROS-MPH) in participants with Attention Deficit Hyperactivity Disorder…
- Trial name
- NCT01933880
- Testing
- Osmotic Release Oral System Methylphenidate Hydrochloride (OROS-MPH), No intervention
- Where
- 6 sites in China
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Xian-Janssen Pharmaceutical Ltd.
Post Procedural Discharge
Enhanced Recovery for Patients Undergoing Radical Cystectomy.
Investigators hypothesize that with the use of enhanced recovery of surgery (ERAS), the postoperative hospital stay after radical cystectomy is reduced, and also postoperative complications are decreased.
- Trial name
- NCT05210673
- Testing
- ERAS, Non ERAS pathway
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Opiate Addiction
Buprenorphine Maintenance for Opioid-Addicted Persons in Jail and Post-Release
The purpose of the study is to determine the feasibility of providing buprenorphine maintenance to opioid-dependent offenders in a jail setting and of transitioning those patients to buprenorphine maintenance in the community…
- Trial name
- NCT00367302
- Testing
- buprenorphine, methadone
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- National Development and Research Institutes, Inc.
Depressive Disorder
Repeat Dose Study of Controlled-Release Paroxetine Tablets and Immediate-Release Paroxetine Tablets in Healthy Japanese Male Subjects
The primary purpose of this study is to compare the steady-state pharmacokinetic profile of paroxetine CR (controlled-release) at the dosage of 25mg/day using the proposed final market tablet of CR 25mg in Japan with that of…
- Trial name
- NCT01000857
- Testing
- Paroxetine CR and Paroxetine IR
- Where
- Japan
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline