Clinical trials: Post Discharge
Pharmacokinetics
A Single Dose, Cross-over Bioequivence Study Comparing Galantamine IR (Immediate Release) Table and Galantmine OS (Oral Solution) in Healthy Volunteers
The purpose of this open-label, single dose, two-treatment, two-period, cross-over study is to evaluate the pharmacokinetic profile and tolerability of galantamine oral solution and galantamine tablet.
- Trial name
- NCT00645554
- Testing
- Galantamine oral solution
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Xian-Janssen Pharmaceutical Ltd.
Subarachnoid Hemorrhage, Lymphatic System Disorder
Radiological Changes of Glymphatic-meningeal Lymphatic Drainage System After Subarachnoid Hemorrhage
Subarachnoid hemorrhage (SAH) is a common and extremely critical disease in neurosurgery. The mortality rate within 30 days of the onset of SAH is as high as 50%, and about 15% of SAH patients die without reaching the hospital.
- Conditions
- Subarachnoid Hemorrhage, Lymphatic System Disorder, Meningeal Lymphatic Vessels
- Trial name
- NCT06444438
- Testing
- subarachnoid hemorrhage
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Healthy
Study to Evaluate Different Extended Release (ER)-Formulations and Multiple Ascending Dosing of AZD3241
The aims of the study are to assess the safety, tolerability and pharmacokinetics of ER tablets of AZD3241 following multiple ascending doses administered to healthy male and female subjects including the effect of food.
- Trial name
- NCT00914303
- Testing
- AZD3241
- Where
- Sweden
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy
BIOAVAILABILITY OF Glimepiride/Extended Release Metformin (GLI/METXR): High Fat Diet Study
Objective: The purpose of this study is to evaluate the effect of food intake in bioavailability (BA) of the combination Glimepiride/ extended release Metformin GLI/METXR (4/850mg) in healthy Mexican volunteers.
- Trial name
- GLMT13 (NCT01437813)
- Testing
- Glimepiride/ Extended release Metformin
- Where
- Mexico
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Laboratorios Silanes S.A. de C.V.
Pain Disorders
Crossover, Single Dose Randomized, Bioequivalence of Ketoprofen Lysine Salt Immediate Release vs Oral Solution
Objectives: The objective of the study was to investigate the bioequivalence between two formulations containing ketoprofen lysine salt (KLS) when administered as single oral doses in two consecutive study periods to healthy male…
- Trial name
- NCT02350296
- Testing
- KSL 40 mg, OKi® 80 mg
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dompé Farmaceutici S.p.A
Opioid Use
Discharge Opioid Education to Decrease Opioid Use After Cesarean
Background: The number of opioid overdose deaths in the United States has quadrupled in 15 years, a dramatic manifestation of the current opioid abuse epidemic.
- Trial name
- NCT03678870
- Testing
- Opioid Education Handout
- Where
- United States
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Depressive Disorder
Single Dose Study of Controlled-Release Paroxetine Tablets in Healthy Japanese Male Subjects
The primary purpose of this study is to to assess the pharmacokinetics of paroxetine after single doses of paroxetine CR at the dose levels of 12.5, 25 and 50mg in healthy Japanese male volunteers.
- Trial name
- NCT00938184
- Testing
- Paroxetine 12.5 milligrams tablet, Paroxetine 25 milligrams tablet, Paroxetine 50 milligrams tablet
- Where
- Japan
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Laceration of Skin, Anxiety
IN Midazolam vs IN Dexmedetomidine vs IN Ketamine During Minimal Procedures in Pediatric ED
Pain in young children has been universally under-recognized due to their inability to describe or localize pain. Improvements in pharmacological interventions are necessary to optimize patient and family experience and allow for…
- Conditions
- Laceration of Skin, Anxiety, Discharge Time
- Trial name
- NCT05934669
- Testing
- Intranasal Midazolam, Intranasal Dexmedetomidine, Intranasal Ketamine
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Drug Counseling
Effect of Pharmacist Provided Drug Information Services After Hospital Discharge
Objective: The aim of this study is to evaluate if offering drug counseling from a hospital pharmacy increases patient satisfaction and sense of security regarding drug treatment after hospital discharge.
- Trial name
- NCT03829995
- Testing
- Drug counseling
- Where
- Denmark
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Region Hovedstadens Apotek
Healthy, Pharmacokinetics of Tamsulosin Hydrochloride
A Study to Compare How Tamsulosin is Absorbed to the Body After Administration of Two Types of Tamsulosin Formulation Under Fed and Fasted Conditions in Chinese Healthy Subjects
The purpose of this study is to investigate the relative bioavailability of two types of prolonged release formulation of tamsulosin hydrochloride in Chinese healthy subjects. The safety of tamsulosin formulation is also compared.
- Trial name
- NCT02138773
- Testing
- Tamsulosin formulation-A, Tamsulosin formulation-B
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma China, Inc.
Depressive Disorder
A Repeat Dose Pharmacokinetic Study Of Paroxetine CR Tablet In Healthy Chinese Subjects
The study was designed to assess the steady-state pharmacokinetic profile of paroxetine after 14 day repeated daily dosing of the controlled release tablet formulation (25 mg) in healthy Chinese subjects.
- Trial name
- NCT00406432
- Testing
- Paroxetine Controlled Release Tablet
- Where
- China
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Sports Physical Therapy
PNF Stretching Compared to SMR on Hamstrings
The use of stretching techniques in the sports world is frequent and widely used for its many effects. One of the main benefits is the gain in flexibility, range of motion and facilitation of the sporting performance.
- Trial name
- NCT05134883
- Testing
- PNF, SMR
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Attention Deficit Hyperactivity Disorder (ADHD)
A Long Term Post-Marketing Study on the EffIcacy and Safety of Osmotic Release Oral System (OROS) Methylphenidate on the Cognitive Functions of Attention Deficit Hyperactivity Disorder (ADHD) Participants
The purpose of this long term post-marketing study is to evaluate the effectiveness and safety of osmotic release oral system methylphenidate hydrochloride (OROS-MPH) in participants with Attention Deficit Hyperactivity Disorder…
- Trial name
- NCT01933880
- Testing
- Osmotic Release Oral System Methylphenidate Hydrochloride (OROS-MPH), No intervention
- Where
- 6 sites in China
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Xian-Janssen Pharmaceutical Ltd.
Burn Scar
Comparison of Length Gain Between Square Flap and Z-plasty in Post Burn Contracture Release
the purpose of this study is to compare the gain in length after postburn contracture release using two different techniques, the more commonly practised z - plasty and relatively newer technique, square flap
- Trial name
- NCT04690543
- Testing
- z-plasty, square flap
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Dentofacial Deformities, Edema
Lymphatic Drainage Massage and Melatonin in Post-Orthognathic Surgery Pain and Edema
Lymphatic drainage massage is one of the most essential techniques for reducing edema. It is a very gentle, monotonous, slow, rhythmic massage applied to the skin's surface.
- Conditions
- Dentofacial Deformities, Edema, Pain
- Trial name
- NCT07062757
- Testing
- no intervention, lymphatic drainage massage, oral melatonin tablet
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Obesity, Morbid, Bariatric Surgery Candidate
Comparison of the Effect of Traditional Method and Eras Protocol in Obesity Surgery
This study was conducted to compare the effectiveness of care based on the "Accelerated Recovery After Surgery (ERAS) Protocol" and the traditional method in bariatric surgery and demonstrate the difference the two methods based…
- Conditions
- Obesity, Morbid, Bariatric Surgery Candidate, Obesity Adult Onset, Obesity Associated Disorder
- Trial name
- NCT05790317
- Testing
- Surgical Procedure with ERAS Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Hypoparathyroidism
Predicting Risk Factors of Postoperative Hypocalcemia After Total Thyroidectomy
With increasing economic pressures to shorten the length of hospital stay, there has been much recent interest in studying risk factors for the development of postoperative hypocalcemia.
- Trial name
- NCT04372225
- Testing
- analysis of hypocalcemia
- Where
- France
- Volunteers
- 477 people, healthy volunteers welcome
- Sponsor
- Aix Marseille Université
Mental Illness
Recovery Bridge: Peer Intervention to Bridge Transition Post Discharge
The time following discharge from psychiatric hospitalization is a high-risk period and has been associated with a range of negative outcomes including high rates of hospital readmission and suicide.
- Trial name
- NCT05758376
- Testing
- Recovery Bridge
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Manual Lymphatic Drainage, Swedish Massage
Comparison of Acute Effect of Different Manual Techniques on Muscle Fascia Stiffness
There are studies investigating the effect of different massage methods on muscle fascia stiffness but the results do not support each other.
- Conditions
- Manual Lymphatic Drainage, Swedish Massage, Muscle Fascia Stiffness
- Trial name
- NCT04324775
- Testing
- Exercise + Manual Lymphatic Drainage, Exercise + Swedish massage
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Marmara University
Trauma, Injury Traumatic
Trauma Follow-Up Prediction (Project 2: Aim 1)
Traumatic injury and inadequate follow-up care are a significant cause of morbidity and 10% of all deaths in sub-Saharan Africa (SSA).
- Conditions
- Trauma, Injury Traumatic, Injuries
- Trial name
- NCT05430165
- Testing
- Standard mHealth screening (triage) tool
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- Mefire Alain Chichom